All Stories

  1. How far have we come with contextual data integration in drug discovery?
  2. Family B G Protein-coupled Receptors and their Ligands: From Structure to Function
  3. Alamandine reverses hyperhomocysteinemia-induced vascular dysfunction via PKA-dependent mechanisms
  4. Understanding Corticotropin Releasing Factor Receptor (CRFR) Activation Using Structural Models
  5. Cyclic MOG 35 – 55 ameliorates clinical and neuropathological features of experimental autoimmune encephalomyelitis
  6. Pharmacometabolomics Informs Quantitative Radiomics for Glioblastoma Diagnostic Innovation
  7. How to Break a Ring: Exploring the Mechanisms of SAS-6 Oligomerisation
  8. Cyclic citrullinated MBP87–99 peptide stimulates T cell responses: Implications in triggering disease
  9. Exploring new scaffolds for angiotensin II receptor antagonism
  10. Fragmentation Patterns of Aromatic 2,5-diketopiperazines Using Liquid chromatography/Mass Spectrometry
  11. In silico studies reveal the mechanisms behind the antioxidant and anti-inflammatory activities of hydroxytyrosol
  12. Computational approaches in target identification and drug discovery
  13. Review cyclic peptides on a merry-go-round; towards drug design
  14. Functional elements of the gastric inhibitory polypeptide receptor: Comparison between secretin- and rhodopsin-like G protein-coupled receptors
  15. Structural-Functional Analysis of the Third Transmembrane Domain of the Corticotropin-releasing Factor Type 1 Receptor
  16. Insights into AT1Receptor Activation through AngII Binding Studies
  17. Ligand Binding Determinants for Angiotensin II Type 1 Receptor from Computer Simulations
  18. Modeling of G Protein-Coupled Receptors Using Crystal Structures: From Monomers to Signaling Complexes
  19. Conformational studies of immunodominant myelin basic protein 1–11 analogues using NMR and molecular modeling
  20. Conformational Analysis of Aliskiren, a Potent Renin Inhibitor, Using High-Resolution Nuclear Magnetic Resonance and Molecular Dynamics Simulations
  21. Towards non-peptide ANG II AT1 receptor antagonists based on urocanic acid: rational design, synthesis and biological evaluation
  22. Structural elucidation of Leuprolide and its analogues in solution: insight into their bioactive conformation
  23. Design and Synthesis of a Cyclic Double Mutant Peptide (cyclo(87−99)[A91,A96]MBP87−99) Induces Altered Responses in Mice after Conjugation to Mannan: Implications in the Immunotherapy of Multiple Sclerosis
  24. Citrullination of Linear and Cyclic Altered Peptide Ligands from Myelin Basic Protein (MBP87−99) Epitope Elicits a Th1 Polarized Response by T Cells Isolated from Multiple Sclerosis Patients: Implications in Triggering Disease
  25. Peptides as Therapeutic Agents or Drug Leads for Autoimmune, Hormone Dependent and Cardiovascular Diseases
  26. Cyclic Peptides in Disease
  27. Round and Round we Go: Cyclic Peptides in Disease