All Stories

  1. Management of Tuberculosis: Are the Practices Homogeneous in High-Income Countries?

    Article • Frontiers in Public Health, September 2020, Frontiers

    Professor Miguel Viveiros

  2. Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil

    Article • Scientific Reports, July 2020, Springer Science + Business Media

    Professor Miguel Viveiros

  3. Epidemic and pandemic viral infections: impact on tuberculosis and the lung

    Article • European Respiratory Journal, June 2020, European Respiratory Society (ERS)

    DELIA Goletti, Professor Miguel Viveiros

  4. Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis: a new strategy to revisit mycobacterial targets and repurpose old drugs

    Article • Expert Review of Anti-infective Therapy, May 2020, Taylor & Francis

    Professor Miguel Viveiros

  5. ABC Efflux Transporters and the Circuitry of miRNAs: Kinetics of Expression in Cancer Drug Resistance

    Article • International Journal of Molecular Sciences, April 2020, MDPI AG

    Professor Miguel Viveiros

  6. Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy)acetamide-based antituberculosis agents

    Article • European Journal of Medicinal Chemistry, April 2020, Elsevier

    Professor Miguel Viveiros

  7. The role of mini-bronchoalveolar lavage fluid in the diagnosis of pulmonary tuberculosis in critically ill patients

    Article • BMC Infectious Diseases, March 2020, Springer Science + Business Media

    Professor Miguel Viveiros

  8. First insights into circulating XDR and pre-XDR Mycobacterium tuberculosis in Southern Brazil

    Article • Infection Genetics and Evolution, March 2020, Elsevier

    Professor Miguel Viveiros

  9. Using genomics to understand the origin and dispersion of multidrug and extensively drug resistant tuberculosis in Portugal

    Article • Scientific Reports, February 2020, Springer Science + Business Media

    Professor Miguel Viveiros

  10. Emergence of multidrug-resistant Mycobacterium tuberculosis of the Beijing lineage in Portugal and Guinea-Bissau: a snapshot of moving clones by whole-genome sequencing

    Article • Emerging Microbes & Infections, January 2020, Taylor & Francis

    Professor Miguel Viveiros

  11. Detection of Drug Resistant Mycobacterium Tuberculosis Strains Using Kit SIRE Nitratase®: a Multicenter Study

    Article • Brazilian Archives of Biology and Technology, January 2020, FapUNIFESP (SciELO)

    Professor Miguel Viveiros

  12. The Contribution of Efflux Pumps in Mycobacterium abscessus Complex Resistance to Clarithromycin

    Article • Antibiotics, September 2019, MDPI AG

    Professor Miguel Viveiros

  13. Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum

    Article • Frontiers in Microbiology, September 2019, Frontiers

    Professor Miguel Viveiros

  14. In silico and in vitro evaluation of tetrahydropyridine compounds as efflux inhibitors in Mycobacterium abscessus

    Article • Tuberculosis, September 2019, Elsevier

    Professor Miguel Viveiros

  15. Genetic Diversity and Molecular Epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil

    Article • American Journal of Tropical Medicine and Hygiene, August 2019, American Society of Tropical Medicine and Hygiene

    Professor Miguel Viveiros

  16. Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs

    Article • Genome Medicine, June 2019, Springer Science + Business Media

    Professor Miguel Viveiros

  17. Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections

    Article • Pharmaceutics, May 2019, MDPI AG

    Professor Miguel Viveiros

  18. Tuberculosis care for migrant patients in Portugal: a mixed methods study with primary healthcare providers

    Article • BMC Health Services Research, April 2019, Springer Science + Business Media

    Professor Miguel Viveiros

  19. Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance

    Article • BMC Genomics, March 2019, Springer Science + Business Media

    Professor Miguel Viveiros

  20. Modifications on C6 and C7 positions of 3-phenylquinolone efflux pump inhibitors led to potent and safe anti-mycobacterial treatment adjuvants

    Article • ACS Infectious Diseases, March 2019, American Chemical Society (ACS)

    Professor Miguel Viveiros

  21. Insights on the Mycobacterium tuberculosis population structure associated with migrants from Portuguese-speaking countries over a three-year period in greater Lisbon, Portugal: Implications at the public health level

    Article • Infection Genetics and Evolution, March 2019, Elsevier

    Professor Miguel Viveiros

  22. Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus

    Article • Frontiers in Genetics, January 2019, Frontiers

    Professor Miguel Viveiros

  23. Tetrahydropyridine derivative as efflux inhibitor in Mycobacterium abscessus

    Article • Journal of Global Antimicrobial Resistance, January 2019, Elsevier

    Professor Miguel Viveiros

  24. Large expert-curated database for benchmarking document

    Article • Database, January 2019, Oxford University Press (OUP)

    Dr Daniel Prieto, Dr James A.L. Brown, Professor Amanda G Thrift, Docent Kutty Selva Nandakumar, Professor Miguel Viveiros, MD Diego A. Valera-Cornejo, Dr Soroush Safaei, Dr Carmen San Martín, Piero Carninci, Dr Florian Rehfeldt, Dr Yoichi Watanabe, Kazuki Ide, Mr Alvin Wong, Dr Adrian Meule, Dr Maurizio Petrelli, Dr Christine McGarrigle, Dr Tristan Reddan, Dr Nicola Roberts, Professor Stefan Lorkowski, Dr Cyrille Goarant, Dr Emma C Hobbs, Dr. Saurab Sharma, Ph.D., Dr Farid Rahimi, Prof. Iseult Lynch, Mirella Walker, Dr Luca Galluzzi, Sophie Ohlsson, Professor Tullio Florio, Dr Rabea A Gadelkareem, Dr Azubuike Christian Ukubuiwe, Prof Gajendra PS Raghava, Prof Jun Shen

  25. A case report of disseminated Mycobacterium colombiense infection in an HIV patient

    Article • International Journal of Mycobacteriology, January 2019, Medknow

    Professor Miguel Viveiros

  26. Regulation of ABCB1 activity by microRNA-200c and microRNA-203a in breast cancer cells: the quest for microRNAs’ involvement in cancer drug resistance

    Article • January 2019, OAE Publishing

    Professor Miguel Viveiros

  27. Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence

    Article • Frontiers in Microbiology, December 2018, Frontiers

    Professor Miguel Viveiros

  28. Advances in the molecular diagnosis of tuberculosis: From probes to genomes

    Article • Infection Genetics and Evolution, November 2018, Elsevier

    Professor Miguel Viveiros

  29. Innovative Implementation of Antibiotic Stewardship supported by a Clinical Decision System

    Article • European Journal of Public Health, November 2018, Oxford University Press (OUP)

    Professor Miguel Viveiros

  30. Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation

    Article • Science Advances, October 2018, American Association for the Advancement of Science

    Professor Miguel Viveiros

  31. Adjuvant therapies against tuberculosis: discovery of a 2-aminothiazole targeting Mycobacterium tuberculosis energetics

    Article • Future Microbiology, September 2018, Future Medicine

    Professor Miguel Viveiros

  32. Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data

    Article • BMC Genomics, August 2018, Springer Science + Business Media

    Professor Miguel Viveiros

  33. Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

    Article • Frontiers in Microbiology, July 2018, Frontiers

    Professor Miguel Viveiros

  34. Participatory-Implementation of an antibiotic stewardship programme supported by an innovative surveillance and clinical decision-support system

    Article • Journal of Hospital Infection, July 2018, Elsevier

    Professor Miguel Viveiros

  35. Antimicrobial and Efflux Inhibitor Activity of Usnic Acid Against Mycobacterium abscessus

    Article • Planta Medica, June 2018, Thieme Publishing Group

    Professor Miguel Viveiros

  36. Fighting antibiotic resistance in Portuguese hospitals: Understanding antibiotic prescription behaviours to better design antibiotic stewardship programmes

    Article • Journal of Global Antimicrobial Resistance, June 2018, Elsevier

    Professor Miguel Viveiros

  37. Activity of Rifabutin and Hemi-synthetic Derivatives Against Mycobacterium abscessus

    Article • Medicinal Chemistry, May 2018, Bentham Science Publishers

    Professor Miguel Viveiros, Andrea von Groll

  38. Contribution of efflux to colistin heteroresistance in a multidrug resistant Acinetobacter baumannii clinical isolate

    Article • Journal of Medical Microbiology, May 2018, Society for General Microbiology

    Professor Miguel Viveiros

  39. Emergence of High-Level Colistin Resistance in an Acinetobacter baumannii Clinical Isolate Mediated by Inactivation of the Global Regulator H-NS

    Article • Antimicrobial Agents and Chemotherapy, April 2018, ASM Journals

    Professor Miguel Viveiros

  40. Author Correction: Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis

    Article • Nature Genetics, April 2018, Springer Science + Business Media

    Professor Miguel Viveiros, Dr Saad Alghamdi

  41. 4.10-P12Perspectives of health care providers in Portugal on the provision of care to migrant patients with TB or HIV-TB co-infection

    Article • European Journal of Public Health, April 2018, Oxford University Press (OUP)

    Professor Miguel Viveiros

  42. Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains

    Article • Antibiotics, March 2018, MDPI AG

    Professor Miguel Viveiros

  43. Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries

    Article • Infection Genetics and Evolution, March 2018, Elsevier

    Professor Miguel Viveiros

  44. First report on antimicrobial resistance and molecular characterization of Salmonella enterica serotype Typhi isolated from human specimens in Luanda, Angola

    Article • Journal of Global Antimicrobial Resistance, February 2018, Elsevier

    Professor Miguel Viveiros

  45. Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis

    Article • Nature Genetics, January 2018, Nature

    Professor Miguel Viveiros, Dr Saad Alghamdi, Dr. Jaime Robledo

  46. Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally

    Article • Scientific Reports, January 2018, Nature

    Professor Miguel Viveiros

  47. Insights on the Mechanism of Action of INH-C10 as an Antitubercular Prodrug

    Article • Molecular Pharmaceutics, November 2017, American Chemical Society (ACS)

    Professor Miguel Viveiros

  48. Active antimicrobial efflux in Staphylococcus epidermidis: building up of resistance to fluoroquinolones and biocides in a major opportunistic pathogen

    Article • Journal of Antimicrobial Chemotherapy, November 2017, Oxford University Press (OUP)

    Professor Miguel Viveiros

  49. Role of Alanine Racemase Mutations in Mycobacterium tuberculosisd-Cycloserine Resistance

    Article • Antimicrobial Agents and Chemotherapy, October 2017, ASM Journals

    Professor Miguel Viveiros, Kurt Krause

  50. HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality

    Article • PLoS ONE, September 2017, PLOS

    Professor Miguel Viveiros

  51. Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium

    Article • European Journal of Medicinal Chemistry, September 2017, Elsevier

    Professor Miguel Viveiros

  52. Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery

    Article • Journal of Medicinal Chemistry, August 2017, American Chemical Society (ACS)

    Professor Miguel Viveiros

  53. Synthesis and Biological Evaluation of Hybrid 1,5- and 2,5-Disubstituted Indoles as Potentially New Antitubercular Agents

    Article • Medicinal Chemistry, July 2017, Bentham Science Publishers

    Professor Miguel Viveiros, Dr. Vasyl Kovalishyn, Dr Maria M B Marques, Filomena Martins

  54. Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus

    Article • Memórias do Instituto Oswaldo Cruz, June 2017, FapUNIFESP (SciELO)

    Professor Miguel Viveiros

  55. Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis

    Article • Frontiers in Microbiology, April 2017, Frontiers

    Professor Miguel Viveiros

  56. Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli

    Article • PeerJ, April 2017, PeerJ

    Professor Miguel Viveiros

  57. Política de Investigação Científica para a Saúde em Portugal: II – Factos e Sugestões

    Article • Acta Médica Portuguesa, March 2017, Ordem dos Medicos

    Professor Miguel Viveiros

  58. In vitro and in silico analysis of the efficiency of tetrahydropyridines as drug efflux inhibitors in Escherichia coli

    Article • International Journal of Antimicrobial Agents, March 2017, Elsevier

    Professor Miguel Viveiros

  59. Política de Investigação Científica para a Saúde em Portugal: I - Enquadramento Europeu e Nacional

    Article • Acta Médica Portuguesa, February 2017, Ordem dos Medicos

    Professor Miguel Viveiros

  60. Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola

    Article • Scientific Reports, February 2017, Nature

    Professor Miguel Viveiros

  61. Thioridazine: A Non-Antibiotic Drug Highly Effective, in Combination with First Line Anti-Tuberculosis Drugs, against Any Form of Antibiotic Resistance of Mycobacterium tuberculosis Due to Its Multi-Mechanisms of Action

    Article • Antibiotics, January 2017, MDPI AG

    Professor Miguel Viveiros

  62. The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs

    Article • Genome Medicine, December 2016, Springer Science + Business Media

    Professor Miguel Viveiros

  63. Genetic diversity, transmission dynamics, and drug resistance of Mycobacterium tuberculosis in Luanda, Angola

    Article • International Journal of Mycobacteriology, December 2016, Elsevier

    Professor Miguel Viveiros

  64. An Experimental Model for the Rapid Screening of Compounds with Potential Use Against Mycobacteria

    Article • Assay and Drug Development Technologies, November 2016, Mary Ann Liebert Inc

    Professor Miguel Viveiros

  65. Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives

    Article • Clinical Microbiology and Infection, November 2016, Elsevier

    Professor Miguel Viveiros, Paolo Miotto

  66. Beyond extensively drug-resistant tuberculosis in lisbon, portugal: a case of linezolid resistance acquisition presenting as an iliopsoas abscess

    Article • International Journal of Antimicrobial Agents, September 2016, Elsevier

    Professor Miguel Viveiros

  67. Plasmid-Borne Antimicrobial Resistance ofStaphylococcus aureusIsolated in a Hospital in Lisbon, Portugal

    Article • Microbial Drug Resistance, June 2016, Mary Ann Liebert Inc

    Professor Miguel Viveiros

  68. Prevention and Control of Antimicrobial Resistant Healthcare-Associated Infections: The Microbiology Laboratory Rocks!

    Article • Frontiers in Microbiology, June 2016, Frontiers

    Professor Miguel Viveiros

  69. Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages

    Article • BMC Genomics, February 2016, Springer Science + Business Media

    Professor Miguel Viveiros

  70. Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis

    Article • PLoS ONE, February 2016, PLOS

    Professor Elsa Anes, Professor Miguel Viveiros

  71. Fluorimetric Methods for Analysis of Permeability, Drug Transport Kinetics, and Inhibition of the ABCB1 Membrane Transporter

    Article • January 2016, Springer Science + Business Media

    Professor Miguel Viveiros

  72. Efflux Pumps in Mycobacteria: Antimicrobial Resistance, Physiological Functions, and Role in Pathogenicity

    Article • January 2016, Springer Science + Business Media

    Professor Miguel Viveiros

  73. Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium

    Article • ACS Infectious Diseases, December 2015, American Chemical Society (ACS)

    Professor Miguel Viveiros

  74. Impact of efflux in the development of multidrug resistance phenotypes in Staphylococcus aureus

    Article • BMC Microbiology, October 2015, Springer Science + Business Media

    Professor Miguel Viveiros

  75. The Role of Efflux Pumps in Schistosoma mansoni Praziquantel Resistant Phenotype

    Article • PLoS ONE, October 2015, PLOS

    Professor Miguel Viveiros, Professor Emanuel Carrilho

  76. Multidrug-Resistant Mycobacterium tuberculosis of the Latin American Mediterranean Lineage, Wrongly Identified as Mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), Causing Active Tuberculosis in South Brazil

    Article • Journal of Clinical Microbiology, September 2015, ASM Journals

    Dr Elis Regina Dalla Costa, Professor Miguel Viveiros

  77. Rational Design and Synthesis of Thioridazine Analogues as Enhancers of the Antituberculosis Therapy

    Article • Journal of Medicinal Chemistry, August 2015, American Chemical Society (ACS)

    Professor Miguel Viveiros

  78. Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences

    Article • Genome Medicine, May 2015, Springer Science + Business Media

    Professor Miguel Viveiros

  79. Direct Detection by the Xpert MTB/RIF Assay and Characterization of Multi and Poly Drug-Resistant Tuberculosis in Guinea-Bissau, West Africa

    Article • PLoS ONE, May 2015, PLOS

    Professor Miguel Viveiros

  80. Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil

    Article • Frontiers in Microbiology, April 2015, Frontiers

    Professor Miguel Viveiros

  81. Enhancing activity of antibiotics against Staphylococcus aureus: Zanthoxylum capense constituents and derivatives

    Article • Phytomedicine, April 2015, Elsevier

    Professor Miguel Viveiros

  82. Genomic diversity of drug-resistant Mycobacterium tuberculosis isolates in Lisbon Portugal: Towards tuberculosis genomic epidemiology

    Article • International Journal of Mycobacteriology, March 2015, Medknow

    Professor Miguel Viveiros

  83. Measuring Efflux and Permeability in Mycobacteria

    Article • January 2015, Springer Science + Business Media

    Professor Miguel Viveiros

  84. Rapid identification of veterinary-relevant Mycobacterium tuberculosis complex species using 16S rDNA, IS6110 and Regions of Difference-targeted dual-labelled hydrolysis probes

    Article • Journal of Microbiological Methods, December 2014, Elsevier

    Professor Miguel Viveiros

  85. Revisiting susceptibility testing in MDR-TB by a standardized quantitative phenotypic assessment in a European multicentre study

    Article • Journal of Antimicrobial Chemotherapy, November 2014, Oxford University Press (OUP)

    Professor Miguel Viveiros

  86. Zanthoxylum capense constituents and derivatives: Effects on the activity of antibiotics against Staphylococcus aureus strains

    Article • Planta Medica, October 2014, Thieme Publishing Group

    Professor Miguel Viveiros

  87. Nested and Multiplex Real-Time PCR Using Dual-Labeled Probes: Detecting and Discriminating Mycobacterium tuberculosis Complex Members in Cultures and Animal Tissues

    Article • October 2014, Springer Science + Business Media

    Professor Miguel Viveiros

  88. Standing of nucleic acid testing strategies in veterinary diagnosis laboratories to uncover Mycobacterium tuberculosis complex members

    Article • Frontiers in Molecular Biosciences, October 2014, Frontiers

    Professor Miguel Viveiros

  89. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains

    Article • Nature Communications, September 2014, Nature

    Professor Miguel Viveiros

  90. Relatedness of Mycobacterium avium subspecies hominissuis clinical isolates of human and porcine origins assessed by MLVA

    Article • Veterinary Microbiology, September 2014, Elsevier

    Professor Miguel Viveiros

  91. Design, synthesis and biological evaluation of novel isoniazid derivatives with potent antitubercular activity

    Article • European Journal of Medicinal Chemistry, June 2014, Elsevier

    Professor Miguel Viveiros, Dr. Vasyl Kovalishyn

  92. PolyTB: A genomic variation map for Mycobacterium tuberculosis

    Article • Tuberculosis, May 2014, Elsevier

    Professor Julian Parkhill, Professor Miguel Viveiros

  93. Gold nanoprobes for multi loci assessment of multi-drug resistant tuberculosis

    Article • Tuberculosis, May 2014, Elsevier

    Dr Pedro Viana Baptista, Professor Miguel Viveiros

  94. GidB mutation as a phylogenetic marker for Q1 cluster Mycobacterium tuberculosis isolates and intermediate-level streptomycin resistance determinant in Lisbon, Portugal

    Article • Clinical Microbiology and Infection, May 2014, Elsevier

    Professor Miguel Viveiros

  95. Membrane transport systems and the biodegradation potential and pathogenicity of genus Rhodococcus

    Article • Frontiers in Physiology, April 2014, Frontiers

    Prof. Carla CCR de Carvalho, Professor Miguel Viveiros

  96. Spectinamides: a challenge, a proof, and a suggestion

    Article • Trends in Microbiology, April 2014, Elsevier

    Professor Miguel Viveiros

  97. Assessment of the BD MGIT TBc Identification Test for the Detection ofMycobacterium tuberculosisComplex in a Network of Mycobacteriology Laboratories

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Professor Miguel Viveiros

  98. Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting

    Article • BMC Genomics, January 2014, Springer Science + Business Media

    Professor Miguel Viveiros

  99. Enhanced Detection of Tuberculous Mycobacteria in Animal Tissues Using a Semi-Nested Probe-Based Real-Time PCR

    Article • PLoS ONE, November 2013, PLOS

    Professor Miguel Viveiros

  100. QSAR Based Design of New Antitubercular Compounds: Improved Isoniazid Derivatives Against Multidrug-Resistant TB

    Article • Current Pharmaceutical Design, November 2013, Bentham Science Publishers

    Professor Miguel Viveiros

  101. Generation and biological evaluation of the products formed from the exposure of Phenothiazine to a 266nm laser beam

    Article • June 2013, SPIE

    Professor Miguel Viveiros

  102. Activity of the efflux pump inhibitor SILA 421 against drug-resistant tuberculosis

    Article • International Journal of Antimicrobial Agents, May 2013, Elsevier

    Professor Miguel Viveiros, Professor Joern Bolstad Christensen

  103. Description of plasmid pSM52, harbouring the gene for the Smr efflux pump, and its involvement in resistance to biocides in a meticillin-resistant Staphylococcus aureus strain

    Article • International Journal of Antimicrobial Agents, May 2013, Elsevier

    Professor Miguel Viveiros

  104. Multidrug Efflux Pumps in Staphylococcus aureus: an Update

    Article • The Open Microbiology Journal, March 2013, Bentham Science Publishers

    Professor Miguel Viveiros

  105. A Simple Method for Assessment of MDR Bacteria for Over-Expressed Efflux Pumps

    Article • The Open Microbiology Journal, March 2013, Bentham Science Publishers

    Professor Miguel Viveiros

  106. High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations

    Article • Journal of Antimicrobial Chemotherapy, March 2013, Oxford University Press (OUP)

    Professor Miguel Viveiros

  107. Resistance to Antimicrobials Mediated by Efflux Pumps in Staphylococcus aureus

    Article • Antibiotics, March 2013, MDPI AG

    Professor Miguel Viveiros

  108. Correction: Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus

    Article • BMC Microbiology, January 2013, Springer Science + Business Media

    Professor Miguel Viveiros

  109. Isothermal DNA amplification coupled to Au-nanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis

    Article • Journal of Nanobiotechnology, January 2013, Springer Science + Business Media

    Professor Miguel Viveiros, Dr Pedro Viana Baptista

  110. Role of the Mmr Efflux Pump in Drug Resistance in Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, November 2012, ASM Journals

    Professor Miguel Viveiros

  111. From multidrug-resistant to extensively drug-resistant tuberculosis in Lisbon, Portugal: the stepwise mode of resistance acquisition

    Article • Journal of Antimicrobial Chemotherapy, October 2012, Oxford University Press (OUP)

    Professor Miguel Viveiros

  112. Inhibitors of mycobacterial efflux pumps as potential boosters for anti-tubercular drugs

    Article • Expert Review of Anti-infective Therapy, September 2012, Taylor & Francis

    Professor Miguel Viveiros

  113. Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex

    Article • Infection Genetics and Evolution, June 2012, Elsevier

    Professor Miguel Viveiros

  114. Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections

    Article • International Journal of Antimicrobial Agents, May 2012, Elsevier

    Professor Miguel Viveiros

  115. Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis

    Article • PLoS ONE, April 2012, PLOS

    Dr Pedro Viana Baptista, Professor Miguel Viveiros

  116. Gold on paper–paper platform for Au-nanoprobe TB detection

    Article • Lab on a Chip, January 2012, Royal Society of Chemistry

    Dr Pedro Viana Baptista, Professor Miguel Viveiros

  117. Genetic response of Salmonella enterica serotype Enteritidis to thioridazine rendering the organism resistant to the agent

    Article • International Journal of Antimicrobial Agents, January 2012, Elsevier

    Professor Séamus Fanning, Professor Miguel Viveiros

  118. Synthesis and thermochemical study of quinoxaline-N-oxides: enthalpies of dissociation of the N-O bond

    Article • October 2011, Wiley

    José Gomes, Professor Miguel Viveiros

  119. Ethidium bromide efflux by Salmonella: modulation by metabolic energy, pH, ions and phenothiazines

    Article • International Journal of Antimicrobial Agents, August 2011, Elsevier

    Professor Séamus Fanning, Professor Miguel Viveiros

  120. Direct Modification of Bioactive Phenothiazines by Exposure to Laser Radiation

    Article • Recent Patents on Anti-Infective Drug Discovery, May 2011, Bentham Science Publishers

    Professor Séamus Fanning, Professor Miguel Viveiros

  121. Antibacterial properties of compounds isolated from Carpobrotus edulis

    Article • International Journal of Antimicrobial Agents, May 2011, Elsevier

    Dr Andrea Vasas, Professor Miguel Viveiros

  122. Effective Therapy with the Neuroleptic Thioridazine as an Adjunct to Second Line of Defence Drugs, and the Potential that Thioridazine Offers for New Patents that Cover a Variety of “New Uses”

    Article • Recent Patents on Anti-Infective Drug Discovery, May 2011, Bentham Science Publishers

    Professor Miguel Viveiros

  123. Inhibition of Drug Efflux in Mycobacteria with Phenothiazines and Other Putative Efflux Inhibitors

    Article • Recent Patents on Anti-Infective Drug Discovery, May 2011, Bentham Science Publishers

    Professor Miguel Viveiros

  124. Role of calcium in the efflux system of Escherichia coli

    Article • International Journal of Antimicrobial Agents, May 2011, Elsevier

    Professor Miguel Viveiros

  125. Thioridazine: Alternative and Potentially Effective Therapy of the XDRTB Patient

    Article • Letters in Drug Design & Discovery, February 2011, Bentham Science Publishers

    Professor Miguel Viveiros

  126. Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance

    Article • BMC Microbiology, January 2011, Springer Science + Business Media

    Professor Miguel Viveiros

  127. Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus

    Article • BMC Microbiology, January 2011, Springer Science + Business Media

    Professor Miguel Viveiros

  128. Inhibition of efflux pumps in meticillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina

    Article • International Journal of Antimicrobial Agents, January 2011, Elsevier

    Professor Miguel Viveiros

  129. Identification of the plasmid-encoded qacA efflux pump gene in meticillin-resistant Staphylococcus aureus (MRSA) strain HPV107, a representative of the MRSA Iberian clone

    Article • International Journal of Antimicrobial Agents, December 2010, Elsevier

    Professor Miguel Viveiros

  130. Physiological characterisation of the efflux pump system of antibiotic-susceptible and multidrug-resistant Enterobacter aerogenes

    Article • International Journal of Antimicrobial Agents, October 2010, Elsevier

    Professor Miguel Viveiros

  131. Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis

    Article • Nanotechnology, September 2010, Institute of Physics Publishing

    Dr Pedro Viana Baptista, Professor Miguel Viveiros

  132. Quinazoline derivatives are efficient chemosensitizers of antibiotic activity in Enterobacter aerogenes, Klebsiella pneumoniae and Pseudomonas aeruginosa resistant strains

    Article • International Journal of Antimicrobial Agents, August 2010, Elsevier

    Professor Miguel Viveiros

  133. Identification of nontuberculous mycobacteria in clinical samples using molecular methods: a 3-year study

    Article • Clinical Microbiology and Infection, August 2010, Elsevier

    Professor Miguel Viveiros

  134. Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!

    Article • International Journal of Antimicrobial Agents, June 2010, Elsevier

    Professor Miguel Viveiros

  135. Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections

    Article • Expert Review of Anti-infective Therapy, April 2010, Taylor & Francis

    Professor Miguel Viveiros

  136. Identification of Efflux-Mediated Multi-drug Resistance in Bacterial Clinical Isolates by Two Simple Methods

    Article • January 2010, Springer Science + Business Media

    Professor Miguel Viveiros

  137. Evaluation of Efflux Activity of Bacteria by a Semi-automated Fluorometric System

    Article • January 2010, Springer Science + Business Media

    Professor Miguel Viveiros

  138. The role of efflux pumps in macrolide resistance in Mycobacterium avium complex

    Article • International Journal of Antimicrobial Agents, December 2009, Elsevier

    Professor Miguel Viveiros

  139. An AcrAB-mediated multidrug-resistant phenotype is maintained following restoration of wild-type activities by efflux pump genes and their regulators

    Article • International Journal of Antimicrobial Agents, December 2009, Elsevier

    Professor Miguel Viveiros

  140. pH Modulation of Efflux Pump Activity of Multi-Drug Resistant Escherichia coli: Protection During Its Passage and Eventual Colonization of the Colon

    Article • PLoS ONE, August 2009, PLOS

    Professor Séamus Fanning, Professor Miguel Viveiros

  141. SILA 421, an inhibitor of efflux pumps of cancer cells, enhances the killing of intracellular extensively drug-resistant tuberculosis (XDR-TB)

    Article • International Journal of Antimicrobial Agents, May 2009, Elsevier

    Professor Miguel Viveiros

  142. Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli

    Article • Journal of Biological Engineering, January 2009, Springer Science + Business Media

    Prof. Carla CCR de Carvalho, Professor Miguel Viveiros

  143. New Methods for the Identification of Efflux Mediated MDR Bacteria, Genetic Assessment of Regulators and Efflux Pump Constituents, Characterization of Efflux Systems and Screening for Inhibitors of Efflux Pumps

    Article • Current Drug Targets, September 2008, Bentham Science Publishers

    Professor Miguel Viveiros

  144. Promising Therapy of XDR-TB/MDR-TB with Thioridazine an Inhibitor of Bacterial Efflux Pumps

    Article • Current Drug Targets, September 2008, Bentham Science Publishers

    Professor Miguel Viveiros

  145. Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide

    Article • Journal of Antimicrobial Chemotherapy, June 2008, Oxford University Press (OUP)

    Professor Miguel Viveiros

  146. Demonstration of intrinsic efflux activity of Escherichia coli K-12 AG100 by an automated ethidium bromide method

    Article • International Journal of Antimicrobial Agents, May 2008, Elsevier

    Professor Miguel Viveiros

  147. The TB laboratory of the future: macrophage-based selection of XDR-TB therapeutics

    Article • Future Microbiology, April 2008, Future Medicine

    Professor Miguel Viveiros

  148. Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis

    Article • Journal of Antimicrobial Chemotherapy, March 2008, Oxford University Press (OUP)

    Professor Miguel Viveiros, Dirk Wagner

  149. Potential role of non-antibiotics (helper compounds) in the treatment of multidrug-resistant Gram-negative infections: mechanisms for their direct and indirect activities

    Article • International Journal of Antimicrobial Agents, March 2008, Elsevier

    Professor Séamus Fanning, Professor Miguel Viveiros

  150. Enhanced Killing of Intracellular Pathogenic Bacteria by Phenothiazines and the Role of K+ Efflux Pumps of the Bacterium and the Killing Macrophage

    Article • Anti-Infective Agents in Medicinal Chemistry, January 2008, Bentham Science Publishers

    Professor Miguel Viveiros

  151. Phenothiazines as Anti-Multi-Drug Resistant Tubercular Agents

    Article • Infectious Disorders - Drug Targets, September 2007, Bentham Science Publishers

    Professor Miguel Viveiros

  152. Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps

    Article • Journal of Antimicrobial Chemotherapy, April 2007, Oxford University Press (OUP)

    Professor Miguel Viveiros

  153. Antibiotic Stress, Genetic Response and Altered Permeability of E. coli

    Article • PLoS ONE, April 2007, PLOS

    Professor Miguel Viveiros, Dr Jean-Marie PAGES

  154. Prolonged exposure of methicillin-resistant Staphylococcus aureus (MRSA) COL strain to increasing concentrations of oxacillin results in a multidrug-resistant phenotype

    Article • International Journal of Antimicrobial Agents, March 2007, Elsevier

    Professor Miguel Viveiros

  155. In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis

    Article • International Journal of Antimicrobial Agents, March 2007, Elsevier

    Professor Miguel Viveiros

  156. Antibacterial activity of ergosterol peroxide againstMycobacterium tuberculosis: dependence upon system and medium employed

    Article • Phytotherapy Research, January 2007, Wiley

    Professor Miguel Viveiros

  157. "Non-Antibiotics": Alternative Therapy for the Management of MDRTB and MRSA in Economically Disadvantaged Countries

    Article • Current Drug Targets, July 2006, Bentham Science Publishers

    Professor Miguel Viveiros

  158. Reserpine, Ouabain and the Calcium Channel Blocker Verapamil, Cause Intracellular Killing of Staphylococcus aureus

    Article • Research Journal of Microbiology, March 2006, Science Alert

    Professor Miguel Viveiros

  159. Direct Application of the INNO-LiPA Rif.TB Line-Probe Assay for Rapid Identification of Mycobacterium tuberculosis Complex Strains and Detection of Rifampin Resistance in 360 Smear-Positive Respiratory Specimens from an Area of High Incidence of Multid...

    Article • Journal of Clinical Microbiology, September 2005, ASM Journals

    Professor Miguel Viveiros

  160. Inducement and Reversal of Tetracycline Resistance in Escherichia coli K-12 and Expression of Proton Gradient-Dependent Multidrug Efflux Pump Genes

    Article • Antimicrobial Agents and Chemotherapy, August 2005, ASM Journals

    Professor Miguel Viveiros

  161. Gamma delta T cell responses associated with the development of tuberculosis in health care workers

    Article • FEMS Immunology & Medical Microbiology, March 2005, Oxford University Press (OUP)

    Professor Miguel Viveiros

  162. Exogenous Re-infection by Multiple Exposures to Mycobacterium tuberculosis Contributes to Subsequent Development of Active Tuberculosis

    Article • American Journal of Immunology, January 2005, Science Publications

    Professor Miguel Viveiros

  163. Inhibition of the Carpobrotus edulis methanol extract on the growth of phagocytosed multidrug-resistant Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus

    Article • Fitoterapia, January 2005, Elsevier

    Professor Miguel Viveiros

  164. Since phenothiazines alter antibiotic susceptibility of microorganisms by inhibiting efflux pumps, are these agents useful for evaluating similar pumps in phenothiazine-sensitive parasites?

    Article • International Journal of Antimicrobial Agents, September 2003, Elsevier

    Professor Miguel Viveiros

  165. Phenothiazines alter resistance of methicillin-resistant strains of Staphylococcus aureus (MRSA) to oxacillin in vitro

    Article • International Journal of Antimicrobial Agents, September 2003, Elsevier

    Professor Miguel Viveiros

  166. Mycobacterial efflux pumps and chemotherapeutic implications

    Article • International Journal of Antimicrobial Agents, September 2003, Elsevier

    Professor Miguel Viveiros

  167. Foreword

    Article • International Journal of Antimicrobial Agents, September 2003, Elsevier

    Professor Miguel Viveiros

  168. Clinical Concentrations of Thioridazine Kill Intracellular Multidrug-Resistant Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, March 2003, ASM Journals

    Professor Miguel Viveiros

  169. Carpobrotus edulis methanol extract inhibits the MDR ef?ux pumps, enhances killing of phagocytosed S. aureus and promotes immune modulation

    Article • Phytotherapy Research, January 2003, Wiley

    Professor Miguel Viveiros

  170. Isoniazid-Induced Transient High-Level Resistance in Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, September 2002, ASM Journals

    Professor Miguel Viveiros

  171. Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed Staphylococcus aureus

    Article • International Journal of Antimicrobial Agents, July 2002, Elsevier

    Professor Miguel Viveiros

  172. Chlorpromazine has intracellular killing activity against phagocytosed Staphylococcus aureus at clinical concentrations

    Article • Journal of Infection and Chemotherapy, January 2002, Elsevier

    Professor Miguel Viveiros

  173. Phenothiazines: potential alternatives for the management of antibiotic resistant infections of tuberculosis and malaria in developing countries

    Article • Tropical Medicine & International Health, December 2001, Wiley

    Professor Miguel Viveiros

  174. Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy

    Article • Journal of Antimicrobial Chemotherapy, May 2001, Oxford University Press (OUP)

    Professor Miguel Viveiros

  175. Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines

    Article • International Journal of Antimicrobial Agents, March 2001, Elsevier

    Professor Miguel Viveiros

  176. Comparative in vitro activity of phenothiazines against multidrug-resistant Mycobacterium tuberculosis

    Article • International Journal of Antimicrobial Agents, September 2000, Elsevier

    Professor Miguel Viveiros

  177. Structural and functional analysis of the gene cluster encoding carotenoid biosynthesis in Mycobacterium aurum A+

    Article • FEMS Microbiology Letters, June 2000, Oxford University Press (OUP)

    Professor Miguel Viveiros

  178. Structural and functional analysis of the gene cluster encoding carotenoid biosynthesis in Mycobacterium aurum A+

    Article • FEMS Microbiology Letters, June 2000, Oxford University Press (OUP)

    Professor Miguel Viveiros

  179. Growth increments and biomineralization process in cephalopod statoliths

    Article • Journal of Experimental Marine Biology and Ecology, May 2000, Elsevier

    Professor Miguel Viveiros

  180. Mycobacteriophage D29 contains an integration system similar to that of the temperate mycobacteriophage L5

    Article • Microbiology, August 1997, Society for General Microbiology

    Professor Miguel Viveiros

  181. Pesquisa de infecção micobacteriana em hemoculturas de doentes com SIDA, usando o sistema BACTEC 460TB

    Article • Revista Portuguesa de Pneumologia, November 1996, Elsevier

    Professor Miguel Viveiros

  182. Improving on the LJ slope - automated liquid culture.

    Article • CABI Publishing

    Professor Miguel Viveiros

  183. Therapy of the XDR-TB patient with thioridazine - an old drug with new applications.

    Article • CABI Publishing

    Professor Miguel Viveiros