All Stories

  1. Terpenoids and phenolics of Micromeria persica
  2. HPLC-Based Activity Profiling for GABAA Receptor Modulators in Murraya exotica
  3. HPLC-based activity profiling for pharmacologically and toxicologically relevant natural products – principles and recent examples
  4. Bryophyllum pinnatum – Reverse Engineering of an Anthroposophic Herbal Medicine
  5. Pharmacokinetics and In Vitro Blood-Brain Barrier Screening of the Plant-Derived Alkaloid Tryptanthrin
  6. HPLC-Based Activity Profiling for hERG Channel Inhibitors in the South African Medicinal Plant Galenia africana
  7. Identification of two new phenathrenones and a saponin as antiprotozoal constituents of Drypetes gerrardii
  8. Identification of dehydroabietc acid from Boswellia thurifera resin as a positive GABAA receptor modulator
  9. Comprehensive analysis of Cirsium spinosissimum Scop., a wild alpine food plant
  10. Mechanism of Chemical Degradation and Determination of Solubility by Kinetic Modeling of the Highly Unstable Sesquiterpene Lactone Nobilin in Different Media
  11. Development and validation of a LC–MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood–brain barrier models
  12. Quantification of the Antiplasmodial Alkaloid Carpaine in Papaya (Carica papaya) Leaves
  13. Bioactive Sesquiterpene Coumarins from Ferula pseudalliacea
  14. Combined Use of Extract Libraries and HPLC-Based Activity Profiling for Lead Discovery: Potential, Challenges, and Practical Considerations
  15. Natural Products as Potential Human Ether-a-Go-Go-Related Gene Channel Inhibitors – Outcomes from a Screening of Widely Used Herbal Medicines and Edible Plants
  16. HPLC-based activity profiling for antiplasmodial compounds in the traditional Indonesian medicinal plant Carica papaya L
  17. Efficient Modulation of γ-Aminobutyric Acid Type A Receptors by Piperine Derivatives
  18. Planta Medica Letters
  19. Natural Products as Potential Human Ether-A-Go-Go-Related Gene Channel Inhibitors – Screening of Plant-Derived Alkaloids
  20. Planta Medica Letters
  21. ChemInform Abstract: Irigermanone, a Noriridal with Unprecedented Methylketone Function, from Iris germanica
  22. Editorial – Planta Medica Abstract Issue
  23. Manoyloxide Sesterterpenoids from Salvia mirzayanii
  24. Gram-scale purification of dehydroevodiamine from Evodia rutaecarpa fruits, and a procedure for selective removal of quaternary indoloquinazoline alkaloids from Evodia extracts
  25. Ethnoveterinary herbal remedies used by farmers in four north-eastern Swiss cantons (St. Gallen, Thurgau, Appenzell Innerrhoden and Appenzell Ausserrhoden)
  26. Structure-Activity Relationship Study of Sesquiterpene Lactones and Their Semi-Synthetic Amino Derivatives as Potential Antitrypanosomal Products
  27. Antitrypanosomal isoflavan quinones from Abrus precatorius
  28. HPLC-Based Activity Profiling for GABAA Receptor Modulators in Adenocarpus cincinnatus
  29. Special Issue in Honor of Professor Otto Sticher
  30. Chemical Composition of the Bark of Tetrapterys mucronata and Identification of Acetylcholinesterase Inhibitory Constituents
  31. Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators
  32. Antitrypanosomal structure–activity-relationship study of synthetic cynaropicrin derivatives
  33. Irigermanone, a Noriridal with Unprecedented Methylketone Function, from Iris germanica
  34. Ethnobotanical survey on wild alpine food plants in Lower and Central Valais (Switzerland)
  35. Zwischen Empirie und Evidenz - (Re)Aktivierung der Veterinärphytotherapie
  36. Antileishmanial activity of 12-methoxycarnosic acid from Salvia repens Burch. ex Benth. (Lamiaceae)
  37. Antitrypanosomal Isothiocyanate and Thiocarbamate Glycosides from Moringa peregrina
  38. Phytochemical profiling of Curcuma kwangsiensis rhizome extract, and identification of labdane diterpenoids as positive GABAA receptor modulators
  39. Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood–brain barrier model for drug permeability studies
  40. Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei
  41. Two New Flavonol Glycosides and a Metabolite Profile of Bryophyllum pinnatum, a Phytotherapeutic Used in Obstetrics and Gynaecology
  42. Antitrypanosomal Triterpenoid with an ε-Lactone E-Ring from Salvia urmiensis
  43. Antiprotozoal Screening of 60 South African Plants, and the Identification of the Antitrypanosomal Germacranolides Schkuhrin I and II
  44. Natural Products-Based Lead Discovery by HPLC Activity Profiling
  45. Antiprotozoal Isoflavan Quinones from Abrus precatorius ssp. africanus
  46. Anti-protozoal activity of aporphine and protoberberine alkaloids from Annickia kummeriae (Engl. & Diels) Setten & Maas (Annonaceae)
  47. Case Study of the Swiss Flora for Prior Phytochemical and Biological Investigations
  48. Abietane Diterpenoids from Salvia sahendica – Antiprotozoal Activity and Determination of Their Absolute Configurations
  49. Bisabololoxide derivatives from Artemisia persica, and determination of their absolute configurations by ECD
  50. Comprehensive analysis of Phyteuma orbiculare L., a wild Alpine food plant
  51. Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with bioassays
  52. Epilepsy in the Renaissance: A survey of remedies from 16th and 17th century German herbals
  53. Development and full validation of an UPLC-MS/MS method for the determination of an anti-allergic indolinone derivative in rat plasma, and application to a preliminary pharmacokinetic study
  54. Disesquiterpene and sesquiterpene coumarins from Ferula pseudalliacea, and determination of their absolute configurations
  55. Library-based Discovery of DYRK1A/CLK1 Inhibitors from Natural Product Extracts
  56. ChemInform Abstract: Hydrangenone, a New Isoprenoid with an Unprecedented Skeleton from Salvia hydrangea.
  57. Pharmacokinetics of Valerenic Acid in Rats after Intravenous and Oral Administrations
  58. Cynaropicrin: The First Plant Natural Product with In Vivo Activity against Trypanosoma brucei
  59. Metabolite Profiling of the Leaves of the Brazilian Folk Medicine Sideroxylon obtusifolium
  60. HPLC-based Activity Profiling - Discovery of Sanggenons as GABA A Receptor Modulators in the Traditional Chinese Drug Sang bai pi ( Morus alba Root Bark)
  61. Discovery of GABA A Receptor Modulator Aristolactone in a Commercial Sample of the Chinese Herbal Drug “ Chaihu ” ( Bupleurum chinense Roots) Unravels Adulteration by Nephrotoxic Aristolochia manshuriensis Roots
  62. Traditional Use of Herbal Remedies in Livestock by Farmers in 3 Swiss Cantons (Aargau, Zurich, Schaffhausen)
  63. Library-Based Discovery and Characterization of Daphnane Diterpenes as Potent and Selective HIV Inhibitors in Daphne gnidium
  64. Identification of GABA A receptor modulators in Kadsura longipedunculata and assignment of absolute configurations by quantum-chemical ECD calculations
  65. Hydrangenone, a New Isoprenoid with an Unprecedented Skeleton from Salvia hydrangea
  66. Triterpenoids with Rare Carbon Skeletons from Salvia hydrangea: Antiprotozoal Activity and Absolute Configurations
  67. Antitrypanosomal sesquiterpene lactones from Saussurea costus
  68. Profiling of isoflavonoids in Iris germanica rhizome extracts by microprobe NMR and HPLC–PDA–MS analysis
  69. Antiplasmodial and Antitrypanosomal Activity of Pyrethrins and Pyrethroids
  70. Identification and Characterization of GABAA Receptor Modulatory Diterpenes from Biota orientalis That Decrease Locomotor Activity in Mice
  71. Positive GABAA Receptor Modulators from Acorus calamus and Structural Analysis of (+)-Dioxosarcoguaiacol by 1D and 2D NMR and Molecular Modeling
  72. HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes
  73. Renaissance remedies: Antiplasmodial protostane triterpenoids from Alisma plantago-aquatica L. (Alismataceae)
  74. hERG Channel Inhibitors in Extracts of Coptidis Rhizoma
  75. Antiplasmodial and Antitrypanosomal Activity of Tanshinone-Type Diterpenoids from Salvia miltiorrhiza
  76. In vitro Screening of Traditional South African Malaria Remedies against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani , and Plasmodium falciparum
  77. Flash chromatography on cartridges for the separation of plant extracts: Rules for the selection of chromatographic conditions and comparison with medium pressure liquid chromatography
  78. Phyteumosides A and B: New Saponins with Unique Triterpenoid Aglycons from Phyteuma orbiculare L.
  79. Pharmacokinetics of α‐mangostin in rats after intravenous and oral application
  80. HPLC-based activity profiling for GABAA receptor modulators from the traditional Chinese herbal drug Kushen (Sophora flavescens root)
  81. Flavone 8‐C‐Glycosides from Haberlea rhodopensisFriv. (Gesneriaceae)
  82. Malaria in the renaissance: Remedies from European herbals from the 16th and 17th century
  83. Telemetry as a Tool to Measure Sedative Effects of a Valerian Root Extract and Its Single Constituents in Mice
  84. Separation and detection of all phosphoinositide isomers by ESI-MS
  85. 70th Birthday of Prof. Dr. rer. nat. Dr. h. c. Adolf Nahrstedt
  86. Ginkgo Biloba Extract Ameliorates Oxidative Phosphorylation Performance and Rescues Aβ-Induced Failure
  87. Oleanane Saponins and Glycerogalactolipids from the Leaves of Guapira graciliflora
  88. Antiplasmodial Lanostanes from the Ganoderma lucidum Mushroom
  89. HPLC-Based Activity Profiling for GABAA Receptor Modulators: A New Dihydroisocoumarin from Haloxylon scoparium
  90. Chemical and Pharmacological Characterization of Herbal Extracts by Profiling Approaches
  91. HPLC-Based Activity Profiling: Discovery of Piperine as a Positive GABAA Receptor Modulator Targeting a Benzodiazepine-Independent Binding Site
  92. HPLC-profiling for antiplasmodial compounds—3-Methoxycarpachromene from Pistacia atlantica
  93. Total Synthesis and Neuritotrophic Activity of Farinosone C and Derivatives
  94. Oleanane saponins from Guapira graciliflora
  95. A comprehensive metabolite profiling of Isatis tinctoria leaf extracts
  96. Regulation of secretases by all‐trans‐retinoic acid
  97. Composition ofIndigo naturalis
  98. Bicyclononane Aldehydes and Antiproliferative Constituents fromAmomum tsao-ko
  99. Medicinal herbs for the treatment of rheumatic disorders—A survey of European herbals from the 16th and 17th century
  100. Effects of Leuzea carthamoides on Human Breast Adenocarcinoma MCF-7 Cells Determined by Gene Expression Profiling and Functional Assays
  101. Albert Hofmann (1906 – 2008) – an Obituary
  102. Glucosinolate Pattern inIsatis tinctoriaandI. indigoticaSeeds
  103. Editorial
  104. Seasonal Changes and Effect of Harvest on Glucosinolates in Isatis leaves
  105. HPLC-Based Activity Profiling Approach for the Discovery of GABA A Receptor Ligands using an Automated Two Microelectrode Voltage Clamp Assay on Xenopus Oocytes
  106. Promotion of cell death or neurite outgrowth in PC-12 and N2a cells by the fungal alkaloid militarinone A depends on basal expression of p53
  107. Goji-Saft, ein neuer Wundertrank für Langlebigkeit und Wohlbefinden? Eine Übersicht zu Inhaltsstoffen, Pharmakologie, Wirkversprechen und Nutzen
  108. Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7
  109. Plants traditionally used in age related brain disorders—A survey of ethnobotanical literature
  110. Extraction and analysis of intact glucosinolates—A validated pressurized liquid extraction/liquid chromatography–mass spectrometry protocol for Isatis tinctoria, and qualitative analysis of other cruciferous plants
  111. Identification of TLC Markers and Quantification by HPLC-MS of Various Constituents in Noni Fruit Powder and Commercial Noni-Derived Products
  112. Comment on Comparison of Protective Effects between Cultured Cordyceps militaris and Natural Cordyceps sinensis against Oxidative Damage
  113. Morinda citrifolia (Noni) Fruit - Phytochemistry, Pharmacology, Safety
  114. Anti-Inflammatory and Neurotrophic Alkaloids from Higher Plants and Fungi
  115. Quantification of Active Principles and Pigments in Leaf Extracts of Isatis tinctoria by HPLC/UV/MS
  116. Noni-Frucht(Morinda citrifolia)- Novel Food oder Phytopharmakon? Eine Übersicht zu Sicherheit, Pharmakologie, Wirkversprechen und Nutzen
  117. Noniosides E - H, New Trisaccharide Fatty Acid Esters from the Fruit ofMorinda citrifolia(Noni)
  118. Quantitative Analysis of Anti-inflammatory and Radical Scavenging Triterpenoid Esters in Evening Primrose Seeds
  119. Are Extraction Methods in Quantitative Assays of Pharmacopoeia Monographs Exhaustive? A Comparison with Pressurized Liquid Extraction
  120. P1–403: Modulation of secretases by all–trans retinoic acid is directed by cPKCs
  121. Anti-arthritic activity of a lipophilic woad ( Isatis tinctoria ) extract
  122. Anti-Inflammatory and Antiallergic Activityin vivoof LipophilicIsatis tinctoriaExtracts and Tryptanthrin
  123. Unravelling the Potential of Natural Products – Biological Profiling of Extracts and New Molecules
  124. (+)-N-Deoxymilitarinone A, a Neuritogenic Pyridone Alkaloid from the Insect Pathogenic Fungus Paecilomyces farinosus
  125. Method Development Spurs Scientific Progress
  126. Flavone C-Glycosides from Isatis tinctoria Leaves
  127. Farinosones A−C, Neurotrophic Alkaloidal Metabolites from the Entomogenous Deuteromycete Paecilomyces farinosus
  128. HPLC-based bioactivity profiling of plant extracts: a kinetic assay for the identification of monoamine oxidase-A inhibitors using human recombinant monoamine oxidase-A
  129. Militarinone A induces differentiation in PC12 cells via MAP and Akt kinase signal transduction pathways
  130. Editorial
  131. HPLC-Based Activity Profiling of Salvia miltiorrhiza for MAO A and iNOS Inhibitory Activities
  132. Tryptanthrin Content inIsatis tinctoriaLeaves - A Comparative Study of Selected Strains and Post-Harvest Treatments
  133. Supercritical carbon dioxide extraction of marigold at high pressures: comparison of analytical and pilot‐scale extraction
  134. Quantitative Analysis of Anti-inflammatory and Radical Scavenging Triterpenoid Esters in Evening Primrose Oil
  135. Rapid analysis of nucleotide-activated sugars by high-performance liquid chromatography coupled with diode-array detection, electrospray ionization mass spectrometry and nuclear magnetic resonance
  136. The Elusive Indigo Precursors in Woad (Isatis tinctoria L.) – Identification of the Major Indigo Precursor, Isatan A, and a Structure Revision of Isatan B
  137. Analysis of aspartyl peptide degradation products by high-performance liquid chromatography and high-performance liquid chromatography-mass spectrometry
  138. Ultraviolet A Induces Generation of Squalene Monohydroperoxide Isomers in Human Sebum and Skin Surface Lipids In Vitro and In Vivo
  139. Novel Tetramic Acids and Pyridone Alkaloids, Militarinones B, C, and D, from the Insect Pathogenic Fungus Paecilomyces militaris
  140. A simple method for preparation of d-rhamnose
  141. Inhibitory Activity of Tryptanthrin on Prostaglandin and Leukotriene Synthesis
  142. Constituents in Evening Primrose Oil with Radical Scavenging, Cyclooxygenase, and Neutrophil Elastase Inhibitory Activities
  143. Occurrence of Stable Foam in the Upper Rhine River Caused by Plant-Derived Surfactants
  144. ChemInform Abstract: Militarinone A, a Neurotrophic Pyridone Alkaloid from Paecilomyces militaris.
  145. ANALYSIS OF NUCLEOTIDE ACTIVATED CARBOHYDRATES BY ION-PAIR HPLC COUPLED ON-LINE TO DAD, ESI-MS AND NMR DETECTION
  146. New Steroidal Glycosides from Balanites aegyptiaca
  147. Quantitative Determination of the Dual COX-2/5-LOX Inhibitor Tryptanthrin in Isatis tinctoria by ESI-LC-MS
  148. Militarinone A, a Neurotrophic Pyridone Alkaloid from Paecilomyces militaris1
  149. A Simple Isolation Method for the Major Catechins in Green Tea Using High-Speed Countercurrent Chromatography
  150. Identification and Isolation of the Cyclooxygenase-2 Inhibitory Principle in Isatis tinctoria
  151. Tensioactive Compounds from the Aquatic Plant Ranunculus fluitans L. (Ranunculaceae)
  152. Efficient method for preparation of highly purified lipopolysaccharides by hydrophobic interaction chromatography
  153. Pressurized liquid extraction of medicinal plants
  154. Application of liquid chromatography-atmospheric pressure ionization mass spectrometry in natural product analysis evaluation and optimization of electrospray and heated nebulizer interfaces
  155. Formation of Sodium Cluster Ions in Electrospray Mass Spectrometry
  156. Molluscicidal Saponins from Guaiacum officinale (Zygophyllaceae)
  157. Molluscicidal Saponins from the Pericarp of Sapindus Saponaria
  158. Effects of solvent composition on molecular ion response in electrospray mass spectrometry: Investigation of the ionization processes
  159. Toxic inhibition of smooth muscle contractility by plant‐derived sesquiterpenes caused by their chemically reactive α‐methylenebutyrolactone functions
  160. Search for chlorinated sesquiterpene lactones in the neurotoxic thistle Centaurea solstitialis by liquid chromatography‐mass spectrometry, and model studies on their possible artifactual formation
  161. Molluscicidal milliamines from Euphorbia milii var. hislopii
  162. Xanthones from Polygala nyikensis
  163. Novel Acetogenins from the Leaves of Annona purpurea
  164. Search for Bitter Principles in Chironia Species by LC-MS and Isolation of a New Secoiridoid Diglycoside from Chironia krebsii
  165. Sinapic acid esters from Polygala virgata
  166. Dimeric xanthones from Garcinia livingstonei
  167. Biphenyls and a xanthone from monnina sylvatica
  168. Acetylated saponins with molluscicidal activity from Sapindus rarak: Unambiguous structure determination by proton nuclear magnetic resonance and quantitative analysis
  169. The pregnane glycoside marsdekoiside a from Marsdenia koi
  170. Cyclohexanecarboxylic‐Acid Derivatives from Psiadia trinervia
  171. Isoflavones and xanthones fromPolygala virgata
  172. Traditional medicinal plants of Thailand XVII Biologically active constituents of Plumeria rubra
  173. Antifungal Biphenyls from Monnina sylvatica
  174. Neurotoxic Sesquiterpenoids from the Yellow Star Thistle Centaurea solstitialis L. (Asteraceae)
  175. Search for New Drugs of Plant Origin
  176. 7. Bioactivity in plants: the link between phytochemistry and medicine
  177. Flavonol glycosides fromMonnina sylvatica
  178. Xanthones fromChironia krebsii
  179. New Developments in the Separation of Natural Products
  180. A Novel Type of Dimeric Secoiridoid Glycoside from Lisianthius jefensis ROBYNSet ELIAS
  181. Polyacetylenes fromArtemisia borealis and their biological activities
  182. Pseudolaric acid B: NMR assignments, conformational analysis and cytotoxicity
  183. New chromonocoumarin (=6H, 7H‐[1]Benzopyrano[4,3‐b][1]benzopyran‐6,7‐dione) derivatives from Polygala fruticosa BERG
  184. Novel Prenylated Xanthones from Garcinia gerrardii HARVEY
  185. Structure Determination of New Isomeric Naphtho[2,3‐b]furan‐4,9‐diones from Tabebuia avellanedae by the selective‐INEPT technique
  186. HPLC Analysis of Montanoa Species for Pharmacologically Active Constituents 1
  187. Phenolic Constituents ofSalvia lavandulifoliassp.Lavandulifolia
  188. An antifungal triterpenoid from mollugo pentaphylla
  189. Antimicrobial flavonoids from Psiadia trinervia and their methylated and acetylated derivatives
  190. Analytical aspects of drugs of natural origin
  191. Traditional medicinal plants of Thailand. 10. Candenatone, a novel purple pigment from Dalbergia candenatensis
  192. 1 H- and 13 C-NMR Spectroscopic Studies of Selected Quassinoids
  193. 10-Demethoxykopsidasinine from Kopsia jasminiflora
  194. NMR Techniques for the Structure Elucidation and Conformational Analysis of Natural Products
  195. Traditional Medicinal Plants of Thailand, VIII. Isoflavonoids of Dalbergia candenatensis
  196. Plant Anticancer Agents, XLIII. (E,E)-7,12-Dioxo-octadeca-8,10-dien-1-oic Acid (Ostopanic Acid), a Cytotoxic Fatty Acid from Ostodes paniculata
  197. A Direct Bioautographic Tlc Assay for Compounds Possessing Antibacterial Activity
  198. Glycosidic Constituents of some European Polygala Species
  199. New Saponins and a Prosapogenin from Polygala chamaebuxus L
  200. Flavonol glycosides from Securidaca diversifolia
  201. Coumarins from Polygala paniculata
  202. Hydroxycinnamic acid esters from Polygala chamaebuxus
  203. A New Pyranocoumarin Diester from Polygala paniculata L
  204. Drug discovery and development with plant-derived compounds