All Stories

  1. Synergistic induction of blood–brain barrier properties
  2. 17-Oxime ethers of oxidized ecdysteroid derivatives modulate oxidative stress in human brain endothelial cells and dose-dependently might protect or damage the blood-brain barrier
  3. Lab-on-a-chip models of the blood–brain barrier: evolution, problems, perspectives
  4. Design, Optimization, and Application of a 3D-Printed Polymer Sample Introduction System for the ICP-MS Analysis of Nanoparticles and Cells
  5. Correction to “Highly Oxidized Ecdysteroids from a Commercial Cyanotis arachnoidea Root Extract as Potent Blood–Brain Barrier Protective Agents”
  6. 17-Oxime ethers of oxidized ecdysteroid derivatives modulate oxidative stress in human brain endothelial cells and dose-dependently might protect or damage the blood-brain barrier
  7. The Use of Sensors in Blood-Brain Barrier-on-a-Chip Devices: Current Practice and Future Directions
  8. Highly Oxidized Ecdysteroids from a Commercial Cyanotis arachnoidea Root Extract as Potent Blood–Brain Barrier Protective Agents
  9. Targeting Human Endothelial Cells with Glutathione and Alanine Increases the Crossing of a Polypeptide Nanocarrier through a Blood–Brain Barrier Model and Entry to Human Brain Organoids
  10. Effects of sub-chronic, in vivo administration of sigma-1 receptor ligands on platelet and aortic arachidonate cascade in streptozotocin-induced diabetic rats
  11. Effects of Hydroxypropyl-Beta-Cyclodextrin on Cultured Brain Endothelial Cells
  12. Cellular Therapy Using Epitope-Imprinted Composite Nanoparticles to Remove α-Synuclein from an In Vitro Model
  13. Distinct Uptake Routes Participate in Silver Nanoparticle Engulfment by Earthworm and Human Immune Cells
  14. Immunofluorescent Evidence for Nuclear Localization of Aromatase in Astrocytes in the Rat Central Nervous System
  15. Effects of sub-chronic, in vivo administration of sigma-1 receptor ligands on platelet and aortic arachidonate cascade in streptozotocin-induced diabetic rats
  16. The Active Role of Pericytes During Neuroinflammation in the Adult Brain
  17. Penetration of the SARS-CoV-2 Spike Protein across the Blood–Brain Barrier, as Revealed by a Combination of a Human Cell Culture Model System and Optical Biosensing
  18. A Triple Combination of Targeting Ligands Increases the Penetration of Nanoparticles across a Blood-Brain Barrier Culture Model
  19. In Vitro Comparative Study of Solid Lipid and PLGA Nanoparticles Designed to Facilitate Nose-to-Brain Delivery of Insulin
  20. Inhibition of NHE-1 Increases Smoke-Induced Proliferative Activity of Barrett’s Esophageal Cell Line
  21. Characterization of a Primate Blood-Brain Barrier Co-Culture Model Prepared from Primary Brain Endothelial Cells, Pericytes and Astrocytes
  22. Identification of Reference Genes for Circadian Studies on Brain Microvessels and Choroid Plexus Samples Isolated from Rats
  23. MAP Kinase Pathways in Brain Endothelial Cells and Crosstalk with Pericytes and Astrocytes Mediate Contrast-Induced Blood–Brain Barrier Disruption
  24. Optically Manipulated Microtools to Measure Adhesion of the Nanoparticle-Targeting Ligand Glutathione to Brain Endothelial Cells
  25. Pitavastatin Ameliorates Lipopolysaccharide-Induced Blood-Brain Barrier Dysfunction
  26. Effect of Lipopolysaccharide-Induced Inflammatory Challenge on β-Glucuronidase Activity and the Concentration of Quercetin and Its Metabolites in the Choroid Plexus, Blood Plasma and Cerebrospinal Fluid
  27. Transendothelial Electrical Resistance Measurement across the Blood–Brain Barrier: A Critical Review of Methods
  28. Bicarbonate Evokes Reciprocal Changes in Intracellular Cyclic di-GMP and Cyclic AMP Levels in Pseudomonas aeruginosa
  29. Surface charge, glycocalyx, and blood-brain barrier function
  30. Development of In Situ Gelling Meloxicam-Human Serum Albumin Nanoparticle Formulation for Nose-to-Brain Application
  31. New Approach in Ocular Drug Delivery: In vitro and ex vivo Investigation of Cyclodextrin-Containing, Mucoadhesive Eye Drop Formulations
  32. ApoE-Targeting Increases the Transfer of Solid Lipid Nanoparticles with Donepezil Cargo across a Culture Model of the Blood–Brain Barrier
  33. Development and Characterization of Potential Ocular Mucoadhesive Nano Lipid Carriers Using Full Factorial Design
  34. The Effect of Sodium Bicarbonate, a Beneficial Adjuvant Molecule in Cystic Fibrosis, on Bronchial Epithelial Cells Expressing a Wild-Type or Mutant CFTR Channel
  35. Simvastatin, edaravone and dexamethasone protect against kainate-induced brain endothelial cell damage
  36. A chip device to determine surface charge properties of confluent cell monolayers by measuring streaming potential
  37. Species-specific sensitivity of Eisenia earthworms towards noble metal nanoparticles: a multiparametric in vitro study
  38. Encapsulation in Polymeric Nanoparticles Enhances the Enzymatic Stability and the Permeability of the GLP-1 Analog, Liraglutide, Across a Culture Model of Intestinal Permeability
  39. Lidocaine turns the surface charge of biological membranes more positive and changes the permeability of blood-brain barrier culture models
  40. Preparation of bivalent agonists for targeting the mu opioid and cannabinoid receptors
  41. Pericytes Suppress Brain Metastasis from Lung Cancer In Vitro
  42. MASP-1 Increases Endothelial Permeability
  43. Dual Action of the PN159/KLAL/MAP Peptide: Increase of Drug Penetration across Caco-2 Intestinal Barrier Model by Modulation of Tight Junctions and Plasma Membrane Permeability
  44. Cerebrovascular Pathology in Hypertriglyceridemic APOB-100 Transgenic Mice
  45. Structural Optimization of Foldamer-Dendrimer Conjugates as Multivalent Agents against the Toxic Effects of Amyloid Beta Oligomers
  46. Niosomes decorated with dual ligands targeting brain endothelial transporters increase cargo penetration across the blood-brain barrier
  47. Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides
  48. Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport
  49. Protection of cultured brain endothelial cells from cytokine-induced damage by α-melanocyte stimulating hormone
  50. Optimization of a combined wet milling process in order to produce poly(vinyl alcohol) stabilized nanosuspension
  51. Biotin and Glutathione Targeting of Solid Nanoparticles to Cross Human Brain Endothelial Cells
  52. From the Cover: In Vitro and In Vivo Blood-Brain Barrier Penetration Studies with the Novel Cyanide Antidote Candidate Dimethyl Trisulfide in Mice
  53. Claudin peptidomimetics modulate tissue barriers for enhanced drug delivery
  54. The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms
  55. Alpha-Melanocyte Stimulating Hormone Protects against Cytokine-Induced Barrier Damage in Caco-2 Intestinal Epithelial Monolayers
  56. Validation of UHPLC–MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro blood-brain barrier and intestinal drug permeability studies
  57. Intraperitoneally administered IgG from patients with amyotrophic lateral sclerosis or from an immune-mediated goat model increase the levels of TNF-α, IL-6, and IL-10 in the spinal cord and serum of mice
  58. Cytotoxicity of Different Excipients on RPMI 2650 Human Nasal Epithelial Cells
  59. Pharmacokinetics and In Vitro Blood-Brain Barrier Screening of the Plant-Derived Alkaloid Tryptanthrin
  60. In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use
  61. Reversible Opening of Intercellular Junctions of Intestinal Epithelial and Brain Endothelial Cells With Tight Junction Modulator Peptides
  62. Restraint Stress-Induced Morphological Changes at the Blood-Brain Barrier in Adult Rats
  63. Anion-/cation-directed reaction routes to polymorphic forms of a pyrazole-type ligand and its coordination compounds with zinc. Key structural differences between polymorphs’
  64. A versatile lab-on-a-chip tool for modeling biological barriers
  65. Evaluation of the Cytotoxicity of α-Cyclodextrin Derivatives on the Caco-2 Cell Line and Human Erythrocytes
  66. Opposite effect of Ca2+/Mg2+ ions on the aggregation of native and precursor-derived Aβ42
  67. Transfer of Opiorphin Through a Blood-Brain Barrier Culture Model
  68. Supermacroporous chemically cross-linked poly(aspartic acid) hydrogels
  69. Molecule helps to open the barrier protecting brain tumors
  70. Cultured cells of the blood–brain barrier from apolipoprotein B-100 transgenic mice: effects of oxidized low-density lipoprotein treatment
  71. In VitroAssays for Assessing BBB Permeability
  72. The Absence of N-Acetyl-D-glucosamine Causes Attenuation of Virulence ofCandida albicansupon Interaction with Vaginal Epithelial CellsIn Vitro
  73. Preparation and investigation of mefenamic acid – polyethylene glycol – sucrose ester solid dispersions
  74. Candesartan Improves Ischemia-Induced Impairment of the Blood–Brain Barrier In Vitro
  75. Low Dose Cranial Irradiation-Induced Cerebrovascular Damage Is Reversible in Mice
  76. Role of the Blood–Brain Barrier in the Nutrition of the Central Nervous System
  77. Preface
  78. Cyclodextrins, Blood–Brain Barrier, and Treatment of Neurological Diseases
  79. Compounds Blocking Methylglyoxal-induced Protein Modification and Brain Endothelial Injury
  80. Sucrose Esters Increase Drug Penetration, But Do Not Inhibit P‐Glycoprotein in Caco‐2 Intestinal Epithelial Cells
  81. Development and validation of a LC–MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood–brain barrier models
  82. Edaravone Protects against Methylglyoxal-Induced Barrier Damage in Human Brain Endothelial Cells
  83. Cilostazol attenuates ischemia–reperfusion-induced blood–brain barrier dysfunction enhanced by advanced glycation endproducts via transforming growth factor-β1 signaling
  84. Hepatocyte growth factor enhances the barrier function in primary cultures of rat brain microvascular endothelial cells
  85. Efflux transport of serum amyloid P component at the blood-brain barrier
  86. In vitro and in vivo characterization of meloxicam nanoparticles designed for nasal administration
  87. pH- and temperature-responsive poly(aspartic acid)-l-poly(N-isopropylacrylamide) conetwork hydrogel
  88. Effects of polymers on the crystallinity of nanonized meloxicam during a co-grinding process
  89. Acute effects of short-chain alkylglycerols on blood-brain barrier properties of cultured brain endothelial cells
  90. Docosahexaenoic Acid Reduces Amyloid-β Induced Toxicity in Cells of the Neurovascular Unit
  91. Kinetic Analysis of the Toxicity of Pharmaceutical Excipients Cremophor EL and RH40 on Endothelial and Epithelial Cells
  92. Cilostazol Strengthens Barrier Integrity in Brain Endothelial Cells
  93. Evaluation of cytotoxicity of surfactants used in self-micro emulsifying drug delivery systems and their effects on paracellular transport in Caco-2 cell monolayer
  94. Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood–brain barrier penetration models
  95. Retinoic acid and hydrocortisone strengthen the barrier function of human RPMI 2650 cells, a model for nasal epithelial permeability
  96. Exposure to Lipopolysaccharide and/or Unconjugated Bilirubin Impair the Integrity and Function of Brain Microvascular Endothelial Cells
  97. The effect of sucrose esters on a culture model of the nasal barrier
  98. Tools for Modelling Blood-Brain Barrier Penetrability
  99. Drug Transport and the Blood-Brain Barrier
  100. Organometallic polymeric carriers for redox triggered release of molecular payloads
  101. Randomly methylated β‐cyclodextrin derivatives enhance taxol permeability through human intestinal epithelial Caco‐2 cell monolayer
  102. Study of the parameters influencing the co-grinding process for the production of meloxicam nanoparticles
  103. Oxygen–glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood–brain barrier
  104. Applicability of sucrose laurate as surfactant in solid dispersions prepared by melt technology
  105. Patented In Vitro Blood-Brain Barrier Models in CNS Drug Discovery
  106. Glial Cells Drive Preconditioning-Induced Blood-Brain Barrier Protection
  107. Intracellular transport of Toxoplasma gondii through the blood–brain barrier
  108. Protection of the Blood-Brain Barrier by Pentosan Against Amyloid-β-Induced Toxicity
  109. Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters
  110. Effect of Nanogold Particles on Coupled Plasmon Resonance on Biomolecule Covered Prepatterned Multilayers
  111. Pitavastatin Strengthens the Barrier Integrity in Primary Cultures of Rat Brain Endothelial Cells
  112. Human Truncated Tau is Using a Different Mechanism from Amyloid-β to Damage the Blood-Brain Barrier
  113. Intranasal Delivery of Human β-Amyloid Peptide in Rats: Effective Brain Targeting
  114. Sodium hyaluronate as a mucoadhesive component in nasal formulation enhances delivery of molecules to brain tissue
  115. Potential use of tight junction modulators to reversibly open membranous barriers and improve drug delivery
  116. A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
  117. Epithelial and endothelial barriers in the olfactory region of the nasal cavity of the rat
  118. Effect of nicotine and polyaromtic hydrocarbons on cerebral endothelial cells
  119. Comparative study of sub-micrometer polymeric structures: Dot-arrays, linear and crossed gratings generated by UV laser based two-beam interference, as surfaces for SPR and AFM based bio-sensing
  120. Bio-sensing based on plasmon-coupling caused by rotated sub-micrometer gratings in metal-dielectric interfacial layers
  121. Pericytes from Brain Microvessels Strengthen the Barrier Integrity in Primary Cultures of Rat Brain Endothelial Cells
  122. Highly activated c-fos expression in specific brain regions (ependyma, circumventricular organs, choroid plexus) of histidine decarboxylase deficient mice in response to formalin-induced acute pain
  123. Atomic force microscopical and surface plasmon resonance spectroscopical investigation of sub-micrometer metal gratings generated by UV laser-based two-beam interference in Au–Ag bimetallic layers
  124. A functional in vitro model of rat blood–brain barrier for molecular analysis of efflux transporters
  125. The NMDA and AMPA/KA Receptors are Involved in Glutamate-Induced Alterations of Occludin Expression and Phosphorylation in Brain Endothelial Cells
  126. Pentosan polysulfate protects brain endothelial cells against bacterial lipopolysaccharide-induced damages
  127. Blood–Brain Barrier Models
  128. Induction of aquaporin 1 by dexamethasone in lipid rafts in immortalized brain microvascular endothelial cells
  129. Sub-micrometer adhesion modulation on polymer surfaces containing gratings produced by two-beam interference
  130. Signaling Mechanisms of HIV-1 Tat-Induced Alterations of Claudin-5 Expression in Brain Endothelial Cells
  131. Puromycin-based purification of rat brain capillary endothelial cell cultures. Effect on the expression of blood-brain barrier-specific properties
  132. Permeability Studies on In Vitro Blood–Brain Barrier Models: Physiology, Pathology, and Pharmacology
  133. Human serum amyloid P component attenuates the bacterial lipopolysaccharide-induced increase in blood–brain barrier permeability in mice
  134. HIV-1 Tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells
  135. Vascular changes play a role in the pathogenesis of necrotizing enterocolitis in asphyxiated newborn pigs
  136. N , N -diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine increases the permeability of primary mouse cerebral endothelial cell monolayers
  137. Adrenomedullin, an Autocrine Mediator of Blood-Brain Barrier Function
  138. Expression of Protein Kinase C Family Members in the Cerebral Endothelial Cells
  139. Adrenomedullin and Migraine
  140. Cerebral Endothelial Cells are a Major Source of Adrenomedullin
  141. Adrenomedullin regulates blood???brain barrier functions in vitro
  142. Enhancing effect of zinc on astroglial and cerebral endothelial histamine uptake11Abbreviations: HA, histamine; FCS, fetal calf serum; MEM, minimal essential medium; and NEM, N-ethylmaleimide.
  143. Adrenomedullin in the cerebral circulation
  144. Asphyxia-induced release of α-melanocyte-stimulating hormone in newborn pigs
  145. Tissue plasminogen activator inhibits P-glycoprotein activity in brain endothelial cells
  146. Effects of N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine on the blood–brain barrier permeability in the rat
  147. Regional differences in asphyxia- and reperfusion-induced cytotoxic and vasogenic brain edema formation in newborn pigs
  148. Mannose-binding lectin and meningococcal disease
  149. Mannose-binding lectin and meningococcal disease
  150. 4-(2-Aminoethyl)benzenesulfonyl fluoride attenuates tumor-necrosis-factor-α-induced blood–brain barrier opening
  151. Cerebral microvascular acid phosphatase isoenzymes may contribute to the histamine-induced changes in the blood-brain barrier permeability
  152. Pentosan in transmissible spongiform encephalopathies
  153. Vasoactive substances produced by cultured rat brain endothelial cells
  154. Expression of glutamate receptors on cultured cerebral endothelial cells
  155. Expression of glutamate receptors on cultured cerebral endothelial cells
  156. Expression of G-protein subtypes in cultured cerebral endothelial cells
  157. Experimental acute pancreatitis results in increased blood–brain barrier permeability in the rat: a potential role for tumor necrosis factor and interleukin 6
  158. Mercury‐stimulated histamine uptake and binding in cultured astroglial and cerebral endothelial cells
  159. Mercury-stimulated histamine uptake and binding in cultured astroglial and cerebral endothelial cells
  160. THE INFLUENCE OF OXYGEN FREE RADICALS ON THE PERMEABILITY OF THE MONOLAYER OF CULTURED BRAIN ENDOTHELIAL CELLS
  161. Intracarotid tumor necrosis factor-α administration increases the blood-brain barrier permeability in cerebral cortex of the newborn pig: quantitative aspects of double-labelling studies and confocal laser scanning analysis
  162. Cultured Vascular Endothelial Cells of the Brain.
  163. Exposure of tumor necrosis factor-α to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin
  164. Penetration of small molecular weight substances through cultured bovine brain capillary endothelial cell monolayers: the early effects of cyclic adenosine 3',5'-monophosphate
  165. Histamine induces a selective albumin permeation through the blood-brain barrierin vitro
  166. Carrier-mediated uptake and release of histamine by cultured rat cerebral endothelial cells
  167. Calcium/Calmodulin‐Stimulated Protein Kinase II Is Present in Primary Cultures of Cerebral Endothelial Cells