All Stories

  1. REACT-PXE: a consensus on diagnosis and future research concerning pseudoxanthoma elasticum (PXE)
  2. Investigating the Association between Cognitive Function with Retinal Thickness, Choroidal Thickness and Lens Opacities in People with and without Down Syndrome
  3. Retinal biomarkers for Alzheimer's disease in the prodromal and preclinical population ‐ The Deep and Frequent Phenotyping study
  4. Zinc in eye health, retinal biology and disease
  5. Development of Bioceramic Bone-Inspired Scaffolds Through Single-Step Melt-Extrusion 3D Printing for Segmental Defect Treatment
  6. 2024 Annual Meeting of the International Network on Ectopic Calcification (INTEC)—Abstract Proceedings
  7. Investigating the eye in Down syndrome as a window to Alzheimer’s disease: the REVEAL protocol – a clinical cross-sectional study
  8. International reporting guidelines for tear fluid research: A Delphi consensus
  9. A comprehensive scoping review of methodological approaches and clinical applications of tear fluid biomarkers
  10. Choroidal and retinal vascular changes in adults with Down syndrome: Insights into the Alzheimer's disease continuum
  11. Resistance and resilience to Alzheimer's disease in Down syndrome
  12. Ultra‐widefield retinal imaging in Down syndrome: A high‐risk population for Alzheimer's disease
  13. Dementia risk reduction in the African context: Multi‐national implementation of multimodal strategies to promote healthy brain aging in Africa (the Africa‐FINGERS project)
  14. Development of dual drug loaded-hydrogel scaffold combining microfluidics and coaxial 3D-printing for intravitreal implantation
  15. Application of Artificial Intelligence in Ophthalmology: An Updated Comprehensive Review
  16. Metabolomic changes in tear fluid following zinc biofortification in the BiZiFED nutritional study: a feasibility study
  17. Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation
  18. Bruch's Membrane Calcification in Pseudoxanthoma Elasticum
  19. Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions
  20. Reduced Cone Density Is Associated with Multiple Sclerosis
  21. Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia
  22. Two-Photon Excited Fluorescence Lifetime Imaging of Tetracycline-Labeled Retinal Calcification
  23. Editorial: Zinc in health and disease management
  24. Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium
  25. Fluorescence Lifetime Imaging of Human Sub-RPE Calcification In Vitro Following Chlortetracycline Infusion
  26. Optimised plasma sample preparation and LC‐MS analysis to support large‐scale proteomic analysis of clinical trial specimens: Application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial
  27. Zinc Supplementation Induced Transcriptional Changes in Primary Human Retinal Pigment Epithelium: A Single-Cell RNA Sequencing Study to Understand Age-Related Macular Degeneration
  28. Retinal Vascular Changes in Alzheimer's Dementia and Mild Cognitive Impairment: A Pilot Study Using Ultra-Widefield Imaging
  29. Ocular Biomarkers for Alzheimer Disease Dementia
  30. Zinc supplementation induced transcriptional changes in primary human retinal pigment epithelium: a single cell RNA sequencing study to understand age-related macular degeneration
  31. Nuclear and cellular, micro and nano calcification in Alzheimer's disease patients and correlation to phosphorylated Tau
  32. Re: Keenan et al.: Cluster Analysis and Genotype-Phenotype Assessment of Geographic Atrophy in Age-Related Macular Degeneration: AREDS2 Report 25 (Ophthalmology. 2021;5(11):1061-1073)
  33. A 2,7-dichlorofluorescein derivative to monitor microcalcifications
  34. A Potential New Role for Zinc in Age-Related Macular Degeneration through Regulation of Endothelial Fenestration
  35. Development of a Genotype Assay for Age-Related Macular Degeneration
  36. Characterization of Calcium Phosphate Spherical Particles in the Subretinal Pigment Epithelium–Basal Lamina Space in Aged Human Eyes
  37. Comment and response to the article “The clinical relevance of visualizing the peripheral retina”by Nicola Quinn, Lajos Csincsik, Erin Flynn, Christine A. Curcio, Szilard Kiss, SriniVas R. Sadda, Ruth Hogg, Tunde Peto & Imre Lengyel.
  38. Predicting Progression to Advanced Age-Related Macular Degeneration from Clinical, Genetic, and Lifestyle Factors Using Machine Learning
  39. Increased choroidal thickness in adults with Down syndrome
  40. Multiplex bioimaging of proteins-related to neurodegenerative diseases in eye sections by laser ablation - Inductively coupled plasma – Mass spectrometry using metal nanoclusters as labels
  41. Retinal phenotyping of variants of Alzheimer's disease using ultra‐widefield retinal images
  42. Genotype- and Phenotype-Based Subgroups in Geographic Atrophy Secondary to Age-Related Macular Degeneration
  43. Integrating Metabolomics, Genomics, and Disease Pathways in Age-Related Macular Degeneration
  44. A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium
  45. Fluorescent Arylphosphonic Acids: Synergic Interactions between Bone and the Fluorescent Core
  46. Nuclear and cellular, micro and nano calcification in Alzheimer’s disease patients and correlation to phosphorylated Tau
  47. Imaging hydroxyapatite in sub-retinal pigment epithelial deposits by fluorescence lifetime imaging microscopy with tetracycline staining
  48. Calcium, Diet, Imaging, and Age-Related Macular Degeneration
  49. Determination of Zn, Cu and Fe in human patients' serum using micro-sampling ICP-MS and sample dilution
  50. Correction to: Optic nerve thinning and neurosensory retinal degeneration in the rTg4510 mouse model of frontotemporal dementia
  51. Retinal thickness as potential biomarker in posterior cortical atrophy and typical Alzheimer’s disease
  52. P1‐273: ASSESSING HETEROGENEITY OF ALZHEIMER'S DISEASE THROUGH THE EYE
  53. Zinc Nutrition and Inflammation in the Aging Retina
  54. Metabolomics in serum of patients with non-advanced age-related macular degeneration reveals aberrations in the glutamine pathway
  55. THU0663 DO ANTIBODIES DIRECTED AGAINST HUMAN CILIARY BODY TISSUE PREDICT THE DEVELOPMENT OF UVEITIS IN JIA- A PRELIMINARY STUDY
  56. The Placental Growth Factor Pathway and Its Potential Role in Macular Degenerative Disease
  57. On the origin of proteins in human drusen: The meet, greet and stick hypothesis
  58. Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer’s disease
  59. Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration
  60. Mediterranean Diet and Incidence of Advanced Age-Related Macular Degeneration
  61. Fluorescence Lifetime Imaging of Tetracycline-Stained Retinal Hydroxyapatite: An Early Biomarker for Age-Related Macular Degeneration?
  62. Optic nerve thinning and neurosensory retinal degeneration in the rTg4510 mouse model of frontotemporal dementia
  63. Metabolomics and Age-Related Macular Degeneration
  64. Calcified nodules in retinal drusen are associated with disease progression in age-related macular degeneration
  65. A new perspective on lipid research in age-related macular degeneration
  66. The clinical relevance of visualising the peripheral retina
  67. Obesity, diabetes and zinc: A workshop promoting knowledge and collaboration between the UK and Israel, november 28–30, 2016 – Israel
  68. Precision medicine for age-related macular degeneration: current developments and prospects
  69. Genetic differences can cause changes in the level of several proteins in blood samples
  70. The effects of zinc supplementation on primary human retinal pigment epithelium
  71. Towards early detection of age-related macular degeneration with tetracyclines and FLIM
  72. Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration
  73. Peripheral Retinal Imaging Biomarkers for Alzheimer’s Disease: A Pilot Study
  74. Localization of the zinc binding tubulin polymerization promoting protein in the mice and human eye
  75. Prevalence of Age-Related Macular Degeneration in Europe
  76. Changes in zinc status and zinc transporters expression in whole blood of patients with Systemic Inflammatory Response Syndrome (SIRS)
  77. Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model
  78. Main biomarkers associated with age-related plasma zinc decrease and copper/zinc ratio in healthy elderly from ZincAge study
  79. RETINAL IMAGING IN POSTERIOR CORTICAL ATROPHY AND TYPICAL ALZHEIMER’S DISEASE
  80. A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration–Like Lesions at the Peripheral Retina
  81. Retinal imaging in early-onset Alzheimer’s disease
  82. Retinal nerve fibre layer (RNFL) thinning in genetic ftd
  83. Correction for Thompson et al., Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye
  84. Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye
  85. Metals in age-related macular degeneration
  86. Zinc-induced self-association of complement C3b and Factor H: Implications for inflammation and age-related macular degeneration
  87. Zinc-induced Self-association of Complement C3b and Factor H: IMPLICATIONS FOR INFLAMMATION AND AGE-RELATED MACULAR DEGENERATION
  88. Zinc Binding to the Tyr402 and His402 Allotypes of Complement Factor H: Possible Implications for Age-Related Macular Degeneration
  89. The His402 allotype of complement factor H show similar self-association to the Tyr402 allotype but exhibits greater self-association in the presence of zinc
  90. Agreement between image grading of conventional (45°) and ultra wide-angle (200°) digital images in the macula in the Reykjavik eye study
  91. Bruch's membrane changes in transgenic mice overexpressing the human biglycan and apolipoprotein b-100 genes
  92. Uncontrolled Zinc- and Copper-Induced Oligomerisation of the Human Complement Regulator Factor H and Its Possible Implications for Function and Disease
  93. Uncontrolled zinc- and copper-induced oligomerisation of human complement factor H and its implications for age-related macular degeneration
  94. Reply to “Comment on: “High concentration of zinc in sub-retinal pigment epithelial deposits” (Lengyel et al.) (Exp. Eye Res. 772–780, 84/4, 2007)”
  95. Comment on: “High concentration of zinc in sub-retinal pigment epithelial deposits” (Lengyel et al.) (Exp. Eye Res. 772–780, 84/4, 2007)
  96. Cure or cause: opposing roles for zinc in age-related macular degeneration
  97. Bio‐avalibale zinc in the outer segments of short wavelength cones
  98. High concentration of zinc in sub-retinal pigment epithelial deposits
  99. Partial and full agonism in endomorphin derivatives: Comparison by null and operational model
  100. Autonomous activity of CaMKII is only transiently increased following the induction of long-term potentiation in the rat hippocampus
  101. Association of Drusen Deposition with Choroidal Intercapillary Pillars in the Aging Human Eye
  102. Enhancement of NMDA responses by β-amyloid peptides in the hippocampus in vivo
  103. Enhanced G-protein activation by a mixture of Abeta(25-35), Abeta(1-40/42) and zinc
  104. S100B-Mediated Inhibition of the Phosphorylation of GFAP Is Prevented by TRTK-12
  105. Molecular pathomechanisms of Alzheimer's disease
  106. Side Chain Modifications Change the Binding and Agonist Properties of Endomorphin 2
  107. Influence of Degradation on Binding Properties and Biological Activity of Endomorphin 1
  108. Receptor constants for endomorphin-1 and endomorphin-1-ol indicate differences in efficacy and receptor occupancy
  109. Preparation of specifically tritiated endomorphins
  110. Auto‐inhibition of Ca2+/calmodulin‐dependent protein kinase II by its ATP‐binding domain
  111. Autonomous activity and autophosphorylation of CAMPK‐II in rat hippocampal slices: effects of tissue preparation
  112. Modulation of the Phosphorylation and Activity of Calcium/Calmodulin‐Dependent Protein Kinase II by Zinc
  113. Phosphorylation of a New Brain-specific Septin, G-septin, by cGMP-dependent Protein Kinase
  114. Simultaneous measurement of tyrosine hydroxylase activity and phosphorylation in bovine adrenal chromaffin cells
  115. Phosphorylation of proteins in chick ciliary ganglion under conditions that induce long-lasting changes in synaptic transmission: phosphoprotein targets for nitric oxide action
  116. α and β subunits of CaM-kinase II are localized in different neurons in chick ciliary ganglion
  117. Characterization of protein kinase and phosphatase systems in chick ciliary ganglion
  118. Calcium/Calmodulin‐Stimulated Protein Kinase II Is Present in Primary Cultures of Cerebral Endothelial Cells
  119. Pathological Phosphorylation Causes Neuronal Death: Effect of Okadaic Acid in Primary Culture of Cerebellar Granule Cells
  120. Zinc can modulate the phosphorylation and activity of CAMK in freshly isolated rat brain capillaries
  121. Chapter 26: Regulation of transendothelial transport in the cerebral microvessels: the role of second messengers-generating systems
  122. Early X-irradiation of rats—4. Decrease in phosphorylation of low molecular weight proteins in the olfactory bulb accompanies the loss of GABAergic microneurons
  123. Kinetics of Protein Phosphorylation in Microvessels Isolated from Rat Brain: Modulation by Second Messengers