All Stories

  1. Does Ataxia Telangiectasia Mutated (ATM) protect testicular and germ cell DNA integrity by regulating the redox status?

    Article • Reproductive Toxicology, August 2016, Elsevier

    Professor Guido R Haenen

  2. Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells

    Article • Molecular Pharmaceutics, June 2016, American Chemical Society (ACS)

    Professor Guido R Haenen, Elias Arner

  3. Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway

    Article • Biochemical Pharmacology, June 2016, Elsevier

    Professor Guido R Haenen

  4. Iron Supplements and Magnesium Peroxide: An Example of a Hazardous Combination in Self-Medication

    Article • Basic & Clinical Pharmacology & Toxicology, May 2016, Wiley

    Professor Guido R Haenen

  5. Is intestinal oxidative stress involved in patients with compensated liver cirrhosis?

    Article • Annals of Hepatology, April 2016, Index Copernicus

    Professor Guido R Haenen

  6. Food-Derived Bioactives Can Protect the Anti-Inflammatory Activity of Cortisol with Antioxidant-Dependent and -Independent Mechanisms

    Article • International Journal of Molecular Sciences, February 2016, MDPI AG

    Professor Guido R Haenen

  7. The effect of prolonged dietary nitrate supplementation on atherosclerosis development

    Article • Atherosclerosis, February 2016, Elsevier

    Professor Guido R Haenen

  8. The tobacco smoke component acrolein induces glucocorticoid resistant gene expression via inhibition of histone deacetylase

    Article • Toxicology Letters, January 2016, Elsevier

    Professor Guido R Haenen

  9. Chemical characteristics for optimizing CYP2E1 inhibition

    Article • Chemico-Biological Interactions, December 2015, Elsevier

    Professor Guido R Haenen

  10. The contribution of the major metabolite 4′-O-methylmonoHER to the antioxidant activity of the flavonoid monoHER

    Article • Chemico-Biological Interactions, September 2015, Elsevier

    Professor Guido R Haenen

  11. Cigarette smoke extract induces the release of extracellular vesicles by airway epithelial cells via cellular carbonyl stress

    Article • September 2015, European Respiratory Society (ERS)

    Professor Guido R Haenen

  12. Once-daily dose regimen of ribavirin is interchangeable with a twice-daily dose regimen

    Article • Pharmacogenomics and Personalized Medicine, August 2015, Dove Medical Press

    Mr Özgür Muhammet Koc, Professor Guido R Haenen

  13. Anticholinergic Accumulation: A Slumbering Interaction between Drugs and Food Supplements

    Article • Basic & Clinical Pharmacology & Toxicology, July 2015, Wiley

    Professor Guido R Haenen

  14. The potential of flavonoids in the treatment of non-alcoholic fatty liver disease

    Article • Critical Reviews in Food Science and Nutrition, April 2015, Taylor & Francis

    Professor Guido R Haenen

  15. The shifting perception on antioxidants: The case of vitamin E and β-carotene

    Article • Redox Biology, April 2015, Elsevier

    Professor Guido R Haenen

  16. The supplement–drug interaction of quercetin with tamsulosin on vasorelaxation

    Article • European Journal of Pharmacology, January 2015, Elsevier

    Professor Guido R Haenen

  17. The flavonoid monoHER promotes the adaption to oxidative stress during the onset of NAFLD

    Article • Biochemical and Biophysical Research Communications, January 2015, Elsevier

    Professor Guido R Haenen

  18. Protection against Chemotaxis in the Anti-Inflammatory Effect of Bioactives from Tomato Ketchup

    Article • PLoS ONE, December 2014, PLOS

    Professor Guido R Haenen

  19. Glutathione revisited: a better scavenger than previously thought

    Article • Frontiers in Pharmacology, November 2014, Frontiers

    Professor Guido R Haenen

  20. Protection by Antioxidant Flavonoids

    Article • Free Radical Biology and Medicine, November 2014, Elsevier

    Professor Guido R Haenen

  21. Nutritional Antioxidants: It Is Time to Categorise

    Article • September 2014, Taylor & Francis

    Professor Guido R Haenen

  22. The antioxidant flavonoid monoHER provides efficient protection and induces the innate Nrf2 mediated adaptation in endothelial cells subjected to oxidative stress

    Article • PharmaNutrition, July 2014, Elsevier

    Professor Guido R Haenen

  23. The flavonoid 7-mono-O-(β-hydroxyethyl)-rutoside is able to protect endothelial cells by a direct antioxidant effect

    Article • Toxicology in Vitro, June 2014, Elsevier

    Professor Guido R Haenen

  24. The Minor Structural Difference between the Antioxidants Quercetin and 4'O-Methylquercetin Has a Major Impact on Their Selective Thiol Toxicity

    Article • International Journal of Molecular Sciences, April 2014, MDPI AG

    Professor Guido R Haenen

  25. Dietary Flavanols Modulate the Transcription of Genes Associated with Cardiovascular Pathology without Changes in Their DNA Methylation State

    Article • PLoS ONE, April 2014, PLOS

    Professor Guido R Haenen

  26. The anti-inflammatory efficacy of dexamethasone is protected by (−)-epicatechin

    Article • PharmaNutrition, April 2014, Elsevier

    Professor Guido R Haenen

  27. Adaptation to acrolein through upregulating the protection by glutathione in human bronchial epithelial cells: The materialization of the hormesis concept

    Article • Biochemical and Biophysical Research Communications, April 2014, Elsevier

    Professor Guido R Haenen

  28. The Effect of Modified Eggs and an Egg-Yolk Based Beverage on Serum Lutein and Zeaxanthin Concentrations and Macular Pigment Optical Density: Results from a Randomized Trial

    Article • PLoS ONE, March 2014, PLOS

    Professor Guido R Haenen

  29. The cocoa flavanol (−)-epicatechin protects the cortisol response

    Article • Pharmacological Research, January 2014, Elsevier

    Professor Guido R Haenen

  30. BEYOND ORAC AND TEAC: PLANT BIOACTIVE COMPONENTS WITH ANTI-OXIDATIVE AND ANTI-INFLAMMATORY ACTIONS

    Article • Acta Horticulturae, January 2014, International Society for Horticultural Science (ISHS)

    Professor Guido R Haenen

  31. Effect of Antioxidant Supplementation on Exercise-Induced Cardiac Troponin Release in Cyclists: A Randomized Trial

    Article • PLoS ONE, November 2013, PLOS

    Professor Guido R Haenen

  32. The flavanol (-)-epicatechin and its metabolites protect against oxidative stress in primary endothelial cells via a direct antioxidant effect

    Article • European Journal of Pharmacology, September 2013, Elsevier

    Professor Guido R Haenen

  33. Ten misconceptions about antioxidants

    Article • Trends in Pharmacological Sciences, August 2013, Elsevier

    Professor Guido R Haenen

  34. Elevated citrate levels in non-alcoholic fatty liver disease: The potential of citrate to promote radical production

    Article • FEBS Letters, June 2013, Wiley

    Professor Guido R Haenen

  35. Astaxanthin Supplementation Does Not Augment Fat Use or Improve Endurance Performance

    Article • Medicine & Science in Sports & Exercise, June 2013, Wolters Kluwer Health

    Professor Guido R Haenen

  36. Atheroprotective effect of dietary walnut intake in ApoE-deficient mice: Involvement of lipids and coagulation factors

    Article • Thrombosis Research, May 2013, Elsevier

    Professor Guido R Haenen

  37. Su1706 Evidence for Intestinal Oxidative Stress in Patients With Compensated Liver Cirrhosis?

    Article • Gastroenterology, May 2013, Elsevier

    Professor Guido R Haenen

  38. Intrauterine exposure to flavonoids modifies antioxidant status at adulthood and decreases oxidative stress-induced DNA damage

    Article • Free Radical Biology and Medicine, April 2013, Elsevier

    Professor Guido R Haenen

  39. (–)-Epicatechin and Its Glucuronidated and Methylated Metabolites Attenuate Intracellular Oxidative Stress: FLAVIOLA Associated

    Article • Free Radical Biology and Medicine, November 2012, Elsevier

    Professor Guido R Haenen

  40. FLAVANOLS: WHAT DO WE KNOW ABOUT THEIR MECHANISMS OF ACTION?

    Article • Free Radical Biology and Medicine, November 2012, Elsevier

    Professor Guido R Haenen

  41. Flavanols Modulate the Transcription of Genes Involved in Cardiovascular Pathology with Heterogenic Changes of Their DNA Methylation State: FLAVIOLA Associated

    Article • Free Radical Biology and Medicine, November 2012, Elsevier

    Professor Guido R Haenen

  42. Competition between Ascorbate and Glutathione for the Oxidized Form of Methylated Quercetin Metabolites and Analogues: Tamarixetin, 4′O-Methylquercetin, Has the Lowest Thiol Reactivity

    Article • Journal of Agricultural and Food Chemistry, September 2012, American Chemical Society (ACS)

    Professor Guido R Haenen

  43. Neutrophils augment LPS-mediated pro-inflammatory signaling in human lung epithelial cells

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, July 2012, Elsevier

    Professor Guido R Haenen

  44. Cereal grains for nutrition and health benefits: Overview of results from in vitro, animal and human studies in the HEALTHGRAIN project

    Article • Trends in Food Science & Technology, June 2012, Elsevier

    Professor Guido R Haenen

  45. The anti-inflammatory effect of lycopene complements the antioxidant action of ascorbic acid and α-tocopherol

    Article • Food Chemistry, May 2012, Elsevier

    Professor Guido R Haenen

  46. Optimizing the bioactive potential of wheat bran by processing

    Article • Food & Function, January 2012, Royal Society of Chemistry

    Professor Guido R Haenen

  47. Pleiotropic Benefit of Monomeric and Oligomeric Flavanols on Vascular Health - A Randomized Controlled Clinical Pilot Study

    Article • PLoS ONE, December 2011, PLOS

    Professor Guido R Haenen

  48. An essential difference in the reactivity of the glutathione adducts of the structurally closely related flavonoids monoHER and quercetin

    Article • Free Radical Biology and Medicine, December 2011, Elsevier

    Professor Guido R Haenen

  49. A Planar Conformation and the Hydroxyl Groups in the B and C Rings Play a Pivotal Role in the Antioxidant Capacity of Quercetin and Quercetin Derivatives

    Article • Molecules, November 2011, MDPI AG

    Professor Guido R Haenen

  50. Effect of bioprocessing of wheat bran in wholemeal wheat breads on the colonic SCFA production in vitro and postprandial plasma concentrations in men

    Article • Food Chemistry, September 2011, Elsevier

    Professor Guido R Haenen, Prof. Dr. Koen Venema

  51. Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis

    Article • Clinical Nutrition, August 2011, Elsevier

    Professor Guido R Haenen

  52. Addition of a Water-Soluble Propofol Formulation to Preservation Solution in Experimental Kidney Transplantation

    Article • Transplantation, August 2011, Wolters Kluwer Health

    Professor Guido R Haenen

  53. Incomplete protection of genetic integrity of mature spermatozoa against oxidative stress

    Article • Reproductive Toxicology, July 2011, Elsevier

    Professor Guido R Haenen

  54. Tubular Epithelial Injury and Inflammation After Ischemia and Reperfusion in Human Kidney Transplantation

    Article • Annals of Surgery, March 2011, Wolters Kluwer Health

    Professor Guido R Haenen

  55. An Essential Difference between the Flavonoids MonoHER and Quercetin in Their Interplay with the Endogenous Antioxidant Network

    Article • PLoS ONE, November 2010, PLOS

    Professor Guido R Haenen

  56. Oxidative stress and antioxidants in interstitial lung disease

    Article • Current Opinion in Pulmonary Medicine, September 2010, Wolters Kluwer Health

    Professor Guido R Haenen

  57. Dry-fractionation of wheat bran increases the bioaccessibility of phenolic acids in breads made from processed bran fractions

    Article • Food Research International, June 2010, Elsevier

    Professor Guido R Haenen

  58. ChemInform Abstract: Synthesis of 5-Substituted Pyrrolo[1,2-b]pyridazines with Antioxidant Properties.

    Article • ChemInform, May 2010, Wiley

    Professor Guido R Haenen

  59. Erythritol is a sweet antioxidant

    Article • Nutrition, April 2010, Elsevier

    Professor Guido R Haenen

  60. Variant VKORC1 and CYP2C9 Alleles in Patients with Diffuse Alveolar Hemorrhage Caused by Oral Anticoagulants

    Article • Molecular Diagnosis & Therapy, February 2010, Springer Science + Business Media

    Professor Guido R Haenen

  61. Prevention of a systematic underestimation of antioxidant activity in competition assays. The impact of unspecific reactions of the reactive species

    Article • Biochemical and Biophysical Research Communications, February 2010, Elsevier

    Professor Guido R Haenen

  62. Antioxidant and anti-inflammatory capacity of bioaccessible compounds from wheat fractions after gastrointestinal digestion

    Article • Journal of Cereal Science, January 2010, Elsevier

    Professor Guido R Haenen

  63. Deconjugation Kinetics of Glucuronidated Phase II Flavonoid Metabolites by β-glucuronidase from Neutrophils

    Article • Drug Metabolism and Pharmacokinetics, January 2010, Japanese Society for the Study of Xenobiotics

    Professor Guido R Haenen

  64. Bioprocessing of Wheat Bran Improves in vitro Bioaccessibility and Colonic Metabolism of Phenolic Compounds

    Article • Journal of Agricultural and Food Chemistry, July 2009, American Chemical Society (ACS)

    Professor Guido R Haenen

  65. Evaluation of the accuracy of antioxidant competition assays: incorrect assumptions with major impact

    Article • Free Radical Biology and Medicine, July 2009, Elsevier

    Professor Guido R Haenen

  66. Characterization of the glutathione conjugate of the semisynthetic flavonoid monoHER

    Article • Free Radical Biology and Medicine, June 2009, Elsevier

    Professor Guido R Haenen

  67. Bioavailability of ferulic acid is determined by its bioaccessibility

    Article • Journal of Cereal Science, March 2009, Elsevier

    Professor Guido R Haenen

  68. Antioxidant status associated with inflammation in sarcoidosis: A potential role for antioxidants

    Article • Respiratory Medicine, March 2009, Elsevier

    Professor Guido R Haenen

  69. Partial bladder outlet obstruction reduces the tissue antioxidant capacity and muscle nerve density of the guinea pig bladder

    Article • Neurourology and Urodynamics, December 2008, Wiley

    Professor Guido R Haenen

  70. Role of Cytochrome P450 Polymorphisms in the Development of Pulmonary Drug Toxicity

    Article • Drug Safety, December 2008, Springer Science + Business Media

    Professor Guido R Haenen

  71. In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers

    Article • Nutrition, July 2008, Elsevier

    Professor Guido R Haenen

  72. Ferulic Acid from Aleurone Determines the Antioxidant Potency of Wheat Grain (Triticum aestivumL.)

    Article • Journal of Agricultural and Food Chemistry, July 2008, American Chemical Society (ACS)

    Professor Guido R Haenen

  73. Lipid Peroxidation Product 4-Hydroxynonenal Contributes to Bladder Smooth Muscle Damage

    Article • Urology, May 2008, Elsevier

    Professor Guido R Haenen

  74. Health effects of quercetin: From antioxidant to nutraceutical

    Article • European Journal of Pharmacology, May 2008, Elsevier

    Professor Guido R Haenen

  75. Antioxidant and anti-inflammatory potency of different wheat varieties and fractions

    Article • Proceedings of The Nutrition Society, May 2008, Cambridge University Press

    Professor Guido R Haenen

  76. Role of Cytochrome P450 Polymorphisms in the Development of Pulmonary Drug Toxicity

    Article • Drug Safety, January 2008, Springer Science + Business Media

    Professor Guido R Haenen

  77. A Single Session of Resistance Exercise Induces Oxidative Damage in Untrained Men

    Article • Medicine & Science in Sports & Exercise, December 2007, Wolters Kluwer Health

    Professor Guido R Haenen

  78. New Insights into Controversies on the Antioxidant Potential of the Olive Oil Antioxidant Hydroxytyrosol

    Article • Journal of Agricultural and Food Chemistry, September 2007, American Chemical Society (ACS)

    Professor Guido R Haenen

  79. Scavenging of reactive species by antioxidants: How to assess antioxidant activity

    Article • Chemico-Biological Interactions, August 2007, Elsevier

    Professor Guido R Haenen

  80. The olive oil antioxidant hydroxytyrosol protects the aorta against oxidative stress

    Article • Chemico-Biological Interactions, August 2007, Elsevier

    Professor Guido R Haenen

  81. Oxidative Degradation of Lipids during Mashing

    Article • Journal of Agricultural and Food Chemistry, July 2007, American Chemical Society (ACS)

    Professor Guido R Haenen

  82. The quercetin paradox

    Article • Toxicology and Applied Pharmacology, July 2007, Elsevier

    Professor Guido R Haenen

  83. Scavenging of Reactive Species by Antioxidants: How to Assess Antioxidant Activity

    Article • Chemico-Biological Interactions, June 2007, Elsevier

    Professor Guido R Haenen

  84. Protection by flavonoids against anthracycline cardiotoxicity: from chemistry to clinical trials

    Article • Cardiovascular Toxicology, May 2007, Springer Science + Business Media

    Professor Guido R Haenen

  85. Oxidative stress reduces the muscarinic receptor function in the urinary bladder

    Article • Neurourology and Urodynamics, January 2007, Wiley

    Professor Guido R Haenen

  86. Effects of Lipoic Acid and Dihydrolipoic Acid on Total Erythrocytic Thiols under Conditions of Restricted Glucose in vitro

    Article • Basic & Clinical Pharmacology & Toxicology, December 2006, Wiley

    Professor Guido R Haenen

  87. Enteral feeding enriched with carotenoids normalizes the carotenoid status and reduces oxidative stress in long-term enterally fed patients

    Article • Clinical Nutrition, December 2006, Elsevier

    Professor Guido R Haenen

  88. Effects of Lipoic Acid and Dihydrolipoic Acid on 4-Aminophenol-Mediated Erythrocytic Toxicity in vitro

    Article • Basic & Clinical Pharmacology & Toxicology, September 2006, Wiley

    Professor Guido R Haenen

  89. CUMENE HYDROPEROXIDE, AN AGENT INDUCING LIPID PEROXIDATION, CAUSES MUSCARINIC RECEPTOR DAMAGE IN THE URINARY BLADDER

    Article • European Urology Supplements, April 2006, Elsevier

    Professor Guido R Haenen

  90. Gene expression in human small intestinal mucosa in vivo is mediated by iron-induced oxidative stress

    Article • Physiological Genomics, February 2006, American Physiological Society

    Professor Guido R Haenen, Professor Chris Evelo

  91. Structure and activity in assessing antioxidant activity in vitro and in vivo

    Article • Environmental Toxicology and Pharmacology, February 2006, Elsevier

    Professor Guido R Haenen

  92. The reversibility of the glutathionyl-quercetin adduct spreads oxidized quercetin-induced toxicity

    Article • Biochemical and Biophysical Research Communications, December 2005, Elsevier

    Professor Guido R Haenen

  93. Biomarkers for Evaluating Antioxidant Effects

    Article • May 2005, Taylor & Francis

    Professor Guido R Haenen

  94. Determination of the antioxidant capacity in blood

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2005, De Gruyter

    Professor Guido R Haenen

  95. Altered antioxidant status in peripheral skeletal muscle of patients with COPD

    Article • Respiratory Medicine, January 2005, Elsevier

    Professor Guido R Haenen, Harry Gosker

  96. No role of DT-diaphorase (NQO1) in the protection against oxidized quercetin

    Article • FEBS Letters, December 2004, Wiley

    Professor Guido R Haenen

  97. A new approach to assess the total antioxidant capacity using the TEAC assay

    Article • Food Chemistry, December 2004, Elsevier

    Professor Guido R Haenen

  98. The extraordinary antioxidant activity of vitamin E phosphate

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, July 2004, Elsevier

    Professor Guido R Haenen

  99. The thiol reactivity of the oxidation product of 3,5,7-trihydroxy-4H-chromen-4-one containing flavonoids

    Article • Toxicology Letters, June 2004, Elsevier

    Professor Guido R Haenen

  100. Antioxidant capacity of reaction products limits the applicability of the Trolox Equivalent Antioxidant Capacity (TEAC) assay

    Article • Food and Chemical Toxicology, January 2004, Elsevier

    Professor Guido R Haenen

  101. Lecithinized copper,zinc-superoxide dismutase as a protector against doxorubicin-induced cardiotoxicity in mice

    Article • Toxicology and Applied Pharmacology, January 2004, Elsevier

    Professor Guido R Haenen

  102. Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore

    Article • FEBS Letters, November 2003, Wiley

    Professor Guido R Haenen

  103. Oxidant metabolism in chronic obstructive pulmonary disease

    Article • European Respiratory Journal, November 2003, European Respiratory Society (ERS)

    Professor Guido R Haenen

  104. 440 Catechol-containing antioxidants shift oxidative damage toward thiol arylation

    Article • Toxicology Letters, September 2003, Elsevier

    Professor Guido R Haenen

  105. Oxidized quercetin reacts with thiols rather than with ascorbate: implication for quercetin supplementation

    Article • Biochemical and Biophysical Research Communications, August 2003, Elsevier

    Professor Guido R Haenen

  106. Bioavailability and pharmacokinetics of the cardioprotecting flavonoid 7-monohydroxyethylrutoside in mice

    Article • Cancer Chemotherapy and Pharmacology, July 2003, Springer Science + Business Media

    Professor Guido R Haenen

  107. Inhibition of various glutathione S-transferase isoenzymes by RRR-α-tocopherol

    Article • Toxicology in Vitro, June 2003, Elsevier

    Professor Guido R Haenen, Professor Chris Evelo

  108. New method to study oxidative damage and antioxidants in the human small bowel: effects of iron application

    Article • AJP Gastrointestinal and Liver Physiology, April 2003, American Physiological Society

    Professor Guido R Haenen

  109. Oxidatives stress in patients with active HCV infection compared to healthy volunteers

    Article • Journal of Hepatology, April 2003, Elsevier

    Professor Guido R Haenen

  110. Superoxide dismutase: the balance between prevention and induction of oxidative damage

    Article • Chemico-Biological Interactions, March 2003, Elsevier

    Professor Guido R Haenen

  111. A critical appraisal of the use of the antioxidant capacity (TEAC) assay in defining optimal antioxidant structures

    Article • Food Chemistry, March 2003, Elsevier

    Professor Guido R Haenen

  112. Lipoic acid: A multifunctional antioxidant

    Article • BioFactors, January 2003, Wiley

    Professor Guido R Haenen

  113. Effect of Vitamin E on Glutathione-Dependent Enzymes

    Article • Drug Metabolism Reviews, January 2003, Taylor & Francis

    Professor Guido R Haenen

  114. Tocotrienols Inhibit Human Glutathione S-Transferase P1-1

    Article • IUBMB Life, August 2002, Wiley

    Professor Guido R Haenen, Professor Chris Evelo

  115. Oxidative damage shifts from lipid peroxidation to thiol arylation by catechol-containing antioxidants

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, August 2002, Elsevier

    Professor Guido R Haenen

  116. The toxicity of antioxidants and their metabolites

    Article • Environmental Toxicology and Pharmacology, July 2002, Elsevier

    Professor Guido R Haenen

  117. The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids

    Article • Biochemical and Biophysical Research Communications, July 2002, Elsevier

    Professor Guido R Haenen

  118. Hypochlorous Acid Is a Potent Inhibitor of Acetylcholinesterase

    Article • Toxicology and Applied Pharmacology, June 2002, Elsevier

    Professor Guido R Haenen

  119. Interactions between Flavonoids and Proteins:  Effect on the Total Antioxidant Capacity

    Article • Journal of Agricultural and Food Chemistry, February 2002, American Chemical Society (ACS)

    Professor Guido R Haenen

  120. Protection of Flavonoids Against Lipid Peroxidation: The Structure Activity Relationship Revisited

    Article • Free Radical Research, January 2002, Taylor & Francis

    Professor Guido R Haenen

  121. The effect of the trolox equivalent antioxidant capacity (TEAC) in plasma on the formation of 4-aminobiphenylhaemoglobin adducts in smokers

    Article • Biomarkers, January 2002, Taylor & Francis

    Professor Guido R Haenen

  122. Hypochlorous acid is a potent inhibitor of GST P1-1

    Article • Chemico-Biological Interactions, October 2001, Elsevier

    Professor Guido R Haenen, Professor Chris Evelo

  123. Peroxynitrite scavenging of flavonoids: structure activity relationship

    Article • Environmental Toxicology and Pharmacology, September 2001, Elsevier

    Professor Guido R Haenen

  124. Masking of antioxidant capacity by the interaction of flavonoids with protein

    Article • Food and Chemical Toxicology, August 2001, Elsevier

    Professor Guido R Haenen

  125. Transcription factor NF-κB as a potential biomarker for oxidative stress

    Article • British Journal Of Nutrition, August 2001, Cambridge University Press

    Professor Guido R Haenen

  126. Inhibition of human glutathione S-transferase P1-1 by tocopherols and α-tocopherol derivatives

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, July 2001, Elsevier

    Professor Guido R Haenen, Professor Chris Evelo

  127. Lipoic Acid

    Article • May 2001, Taylor & Francis

    Professor Guido R Haenen

  128. The measurement of iron-induced oxidative stress in the intestine using a novel intestinal perfusion technique

    Article • Gastroenterology, April 2001, Elsevier

    Professor Guido R Haenen

  129. The measurement of iron-induced oxidative stress in the intestine using a novel intestinal perfusion technique

    Article • Gastroenterology, April 2001, Elsevier

    Professor Guido R Haenen

  130. ChemInform Abstract: Synthesis of Novel 3,7-Substituted-2-(3′,4′-dihydroxyphenyl)flavones with Improved Antioxidant Activity.

    Article • ChemInform, March 2001, Wiley

    Professor Guido R Haenen

  131. No reduction of α-tocopherol quinone by glutathione in rat liver microsomes

    Article • Biochemical Pharmacology, March 2001, Elsevier

    Professor Guido R Haenen, Professor Chris Evelo

  132. Nuclear factor-κB activation is higher in peripheral blood mononuclear cells of male smokers

    Article • Environmental Toxicology and Pharmacology, March 2001, Elsevier

    Professor Guido R Haenen

  133. Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups

    Article • Toxicology in Vitro, February 2001, Elsevier

    Professor Guido R Haenen

  134. α-Tocopherol Inhibits Human Glutathione S-Transferase π

    Article • Biochemical and Biophysical Research Communications, January 2001, Elsevier

    Professor Guido R Haenen, Professor Chris Evelo

  135. Synthesis of 5-Substituted Pyrrolo[1,2-b]pyridazines with Antioxidant Properties

    Article • Archiv der Pharmazie, January 2001, Wiley

    Professor Guido R Haenen

  136. Protection against Nitric Oxide Toxicity by Tea

    Article • Journal of Agricultural and Food Chemistry, November 2000, American Chemical Society (ACS)

    Professor Guido R Haenen

  137. Synthesis of 1-Substituted 7-Cyano-2,3-diphenylindolizines and Evaluation of Antioxidant Properties

    Article • European Journal of Organic Chemistry, November 2000, Wiley

    Professor Guido R Haenen

  138. Synthesis of Novel 3,7-Substituted-2-(3‘,4‘-dihydroxyphenyl)flavones with Improved Antioxidant Activity

    Article • Journal of Medicinal Chemistry, October 2000, American Chemical Society (ACS)

    Professor Guido R Haenen

  139. Thiazoloindans and Thiazolobenzopyrans:  A Novel Class of Orally Active Central Dopamine (Partial) Agonists

    Article • Journal of Medicinal Chemistry, September 2000, American Chemical Society (ACS)

    Professor Guido R Haenen

  140. Tyrosine as important contributor to the antioxidant capacity of seminal plasma

    Article • Chemico-Biological Interactions, July 2000, Elsevier

    Professor Guido R Haenen

  141. Reduction of the NO-mediated response in the rat aorta by metalloporphyrins

    Article • Canadian Journal of Physiology and Pharmacology, June 2000, Canadian Science Publishing

    Professor Guido R Haenen

  142. Flavonoids can replace α-tocopherol as an antioxidant

    Article • FEBS Letters, May 2000, Wiley

    Professor Guido R Haenen

  143. Pharmaceutical Compounds with Antioxidant Activity

    Article • January 2000, Springer Science + Business Media

    Professor Guido R Haenen

  144. Reduction of the NO-mediated response in the rat aorta by metalloporphyrins

    Article • Canadian Journal of Physiology and Pharmacology, January 2000, Canadian Science Publishing

    Professor Guido R Haenen

  145. Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures

    Article • Food Chemistry, September 1999, Elsevier

    Professor Guido R Haenen

  146. Nitric oxide synthase inhibition by dimaprit and dimaprit analogues

    Article • British Journal of Pharmacology, May 1999, Wiley

    Professor Guido R Haenen

  147. [50] Nitric oxide radical scavenging of flavonoids

    Article • January 1999, Elsevier

    Professor Guido R Haenen

  148. Inhibition of lipid peroxidation mediated by indolizines

    Article • Bioorganic & Medicinal Chemistry Letters, July 1998, Elsevier

    Professor Guido R Haenen

  149. The pharmacology of the antioxidant lipoic acid

    Article • General Pharmacology The Vascular System, September 1997, Elsevier

    Professor Guido R Haenen

  150. Peroxynitrite Scavenging by Wines

    Article • Journal of Agricultural and Food Chemistry, September 1997, American Chemical Society (ACS)

    Professor Guido R Haenen

  151. Peroxynitrite Scavenging by Flavonoids

    Article • Biochemical and Biophysical Research Communications, July 1997, Elsevier

    Professor Guido R Haenen

  152. The Use of Humanin VitroMetabolic Parameters to Explore the Risk Assessment of Hazardous Compounds: The Case of Ethylene Dibromide

    Article • Toxicology and Applied Pharmacology, March 1997, Elsevier

    Professor Guido R Haenen

  153. Pitfalls in a Method for Assessment of Total Antioxidant Capacity

    Article • Free Radical Research, January 1997, Taylor & Francis

    Professor Guido R Haenen

  154. The Role of Lipoic Acid in the Treatment of Diabetic Polyneuropathy

    Article • Drug Metabolism Reviews, January 1997, Taylor & Francis

    Professor Guido R Haenen

  155. Combined non-enzymatic and enzymatic reduction favors bioactivation of racemic lipoic acid: an advantage of a racemic drug?

    Article • Chirality, January 1997, Wiley

    Professor Guido R Haenen

  156. Combined non‐enzymatic and enzymatic reduction favors bioactivation of racemic lipoic acid: an advantage of a racemic drug?

    Article • Chirality, January 1997, Wiley

    Professor Guido R Haenen

  157. Reduction of lipoic acid by lipoamide dehydrogenase

    Article • Biochemical Pharmacology, February 1996, Elsevier

    Professor Guido R Haenen

  158. Nitric Oxide Radical Scavenging by Wines

    Article • Journal of Agricultural and Food Chemistry, January 1996, American Chemical Society (ACS)

    Professor Guido R Haenen

  159. Differences in Cytochrome P450-Mediated Biotransformation of 1,2-Dichlorobenzene by Rat and Man:  Implications for Human Risk Assessment

    Article • Chemical Research in Toxicology, January 1996, American Chemical Society (ACS)

    Professor Guido R Haenen

  160. Flavonoids as Scavengers of Nitric Oxide Radical

    Article • Biochemical and Biophysical Research Communications, September 1995, Elsevier

    Professor Guido R Haenen

  161. Stability of blood (pro)vitamins during four years of storage at −20 °C: Consequences for epidemiologic research

    Article • Journal of Clinical Epidemiology, August 1995, Elsevier

    Professor Guido R Haenen

  162. Enzymatically reduced lipoic acid may regenerate glutathione and vitamin C

    Article • Pharmacological Research, January 1995, Elsevier

    Professor Guido R Haenen

  163. Reliable and Sensitive HPLC Method with Fluorometric Detection for the Analysis of Vitamin B6 in Foods and Feeds.

    Article • Journal of Agricultural and Food Chemistry, July 1994, American Chemical Society (ACS)

    Professor Guido R Haenen

  164. Cimetidine and other H2 receptor antagonists as powerful hydroxyl radical scavengers

    Article • Chemico-Biological Interactions, February 1993, Elsevier

    Professor Guido R Haenen

  165. Scavenging of hypochlorous acid by lipoic acid

    Article • Biochemical Pharmacology, November 1991, Elsevier

    Professor Guido R Haenen

  166. Oxidants and antioxidants: State of the art

    Article • The American Journal of Medicine, September 1991, Elsevier

    Professor Guido R Haenen

  167. Activation of the microsomal glutathione S-transferase by metabolites of α-methyldopa

    Article • Archives of Biochemistry and Biophysics, May 1991, Elsevier

    Professor Guido R Haenen

  168. Interplay between ascorbic acid, α-tocopherol, glutathione and lipoic acid in the protection against microsomal lipid peroxidation

    Article • European Journal of Pharmacology, July 1990, Elsevier

    Professor Guido R Haenen

  169. Reduction of β-adrenoceptor function In the heart by oxidative stress

    Article • European Journal of Pharmacology, July 1990, Elsevier

    Professor Guido R Haenen

  170. Reduction of β-adrenoceptor function by oxidative stress in the heart

    Article • Free Radical Biology and Medicine, January 1990, Elsevier

    Professor Guido R Haenen

  171. Regulation of Lipid Peroxidation by Glutathione and Lipoic Acid: Involvement of Liver Microsomal Vitamin E Free Radical Reductase

    Article • January 1990, Springer Science + Business Media

    Professor Guido R Haenen

  172. Cytochrome P-450 and Vitamin E Free Radical Reductase: Formation of and Protection Against Free Radicals

    Article • January 1990, Springer Science + Business Media

    Professor Guido R Haenen

  173. Effect of thiols on lipid peroxidation in rat liver microsomes

    Article • Chemico-Biological Interactions, January 1989, Elsevier

    Professor Guido R Haenen

  174. Contribution of 4-hydroxy-2,3-trans-nonenal to the reduction of β-adrenoceptor function in the heart by oxidative stress

    Article • Life Sciences, January 1989, Elsevier

    Professor Guido R Haenen

  175. Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation

    Article • Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, December 1988, Elsevier

    Professor Guido R Haenen

  176. Activation of the microsomal glutathione-s-transferase and reduction of the glutathione dependent protection against lipid peroxidation by acrolein

    Article • Biochemical Pharmacology, May 1988, Elsevier

    Professor Guido R Haenen

  177. The effect of chronic adriamycin treatment on heart kidney and liver tissue of male and female rat

    Article • Archives of Toxicology, February 1988, Springer Science + Business Media

    Professor Guido R Haenen

  178. 4-Hydroxy-2,3-trans-nonenal stimulates microsomal lipid peroxidation by reducing the glutathione-dependent protection

    Article • Archives of Biochemistry and Biophysics, December 1987, Elsevier

    Professor Guido R Haenen

  179. Cytochrome P-450 and glutathione: what is the significance of their interrelationship in lipid peroxidation?

    Article • Trends in Biochemical Sciences, December 1984, Elsevier

    Professor Guido R Haenen

  180. Sex differences in the cellular defence system against free radicals from oxygen or drug metabolites in rat

    Article • Archives of Toxicology, December 1984, Springer Science + Business Media

    Professor Guido R Haenen

  181. Protection against lipid peroxidation by a microsomal glutathione-dependent labile factor

    Article • FEBS Letters, August 1983, Wiley

    Professor Guido R Haenen