All Stories

  1. Working memory training efficacy in COPD: the randomised double-blind placebo-controlled Cogtrain trial

    Article • ERJ Open Research, October 2021, European Respiratory Society (ERS)

    Harry Gosker

  2. Network Analysis of Genome-Wide Association Studies for Chronic Obstructive Pulmonary Disease in the Context of Biological Pathways

    Article • American Journal of Respiratory and Critical Care Medicine, December 2019, American Thoracic Society

    Harry Gosker, Kelly Stewart

  3. Safety and Tolerability of Targeted Medical Nutrition for Cachexia in Non-Small-Cell Lung Cancer: A Randomized, Double-Blind, Controlled Pilot Trial

    Article • Nutrition and Cancer, July 2019, Taylor & Francis

    Professor Alessandro Laviano, Harry Gosker, Maria Bech

  4. Cross-sectional and longitudinal assessment of muscle from regular chest computed tomography scans: L1 and pectoralis muscle compared to L3 as reference in non-small cell lung cancer

    Article • International Journal of Chronic Obstructive Pulmonary Disease, April 2019, Dove Medical Press

    Harry Gosker

  5. Coordinated regulation of skeletal muscle mass and metabolic plasticity during recovery from disuse

    Article • The FASEB Journal, January 2019, Federation of American Societies For Experimental Biology (FASEB)

    Harry Gosker, Anita Kneppers

  6. Cognitive impairment in chronic obstructive pulmonary disease: disease burden, determinants and possible future interventions

    Article • Expert Review of Respiratory Medicine, October 2018, Taylor & Francis

    Martijn Van Beers, Harry Gosker, Daisy Janssen

  7. Increased Myogenic and Protein Turnover Signaling in Skeletal Muscle of Chronic Obstructive Pulmonary Disease Patients With Sarcopenia

    Article • Journal of the American Medical Directors Association, July 2017, Elsevier

    Harry Gosker

  8. The development and validation of the Bronchiectasis Health Questionnaire

    Article • European Respiratory Journal, May 2017, European Respiratory Society (ERS)

    Harry Gosker

  9. Rasch analysis and impact factor methods both yield valid and comparable measures of health status in interstitial lung disease

    Article • Journal of Clinical Epidemiology, September 2015, Elsevier

    Toby Maher, Harry Gosker

  10. TNF-α-Induced NF-κB Activation Stimulates Skeletal Muscle Glycolytic Metabolism Through Activation of HIF-1α

    Article • Endocrinology, May 2015, Endocrine Society

    Harry Gosker

  11. Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, May 2015, Elsevier

    Harry Gosker

  12. Impaired exercise training-induced muscle fiber hypertrophy and Akt/mTOR pathway activation in hypoxemic patients with COPD

    Article • Journal of Applied Physiology, April 2015, American Physiological Society

    Harry Gosker

  13. Nutritional advances in patients with respiratory diseases: FIGURE 1

    Article • European Respiratory Review, February 2015, European Respiratory Society (ERS)

    Harry Gosker

  14. Differential sensitivity of oxidative and glycolytic muscles to hypoxia-induced muscle atrophy

    Article • Journal of Applied Physiology, January 2015, American Physiological Society

    Harry Gosker

  15. Cigarette Smoke Extract Induces a Phenotypic Shift in Epithelial Cells; Involvement of HIF1α in Mesenchymal Transition

    Article • PLoS ONE, October 2014, PLOS

    Harry Gosker

  16. Nutritional assessment and therapy in COPD: a European Respiratory Society statement

    Article • European Respiratory Journal, September 2014, European Respiratory Society (ERS)

    Harry Gosker

  17. Hypoxia differentially regulates muscle oxidative fiber type and metabolism in a HIF-1α-dependent manner

    Article • Cellular Signalling, September 2014, Elsevier

    Harry Gosker

  18. An Official American Thoracic Society/European Respiratory Society Statement: Update on Limb Muscle Dysfunction in Chronic Obstructive Pulmonary Disease

    Article • American Journal of Respiratory and Critical Care Medicine, May 2014, American Thoracic Society

    Harry Gosker, josep roca

  19. Activation of alternative NF-κB signaling during recovery of disuse-induced loss of muscle oxidative phenotype

    Article • AJP Endocrinology and Metabolism, March 2014, American Physiological Society

    Harry Gosker

  20. The Muscle Oxidative Regulatory Response to Acute Exercise Is Not Impaired in Less Advanced COPD Despite a Decreased Oxidative Phenotype

    Article • PLoS ONE, February 2014, PLOS

    Harry Gosker

  21. Classical NF-κB activation impairs skeletal muscle oxidative phenotype by reducing IKK-α expression

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, February 2014, Elsevier

    Harry Gosker

  22. Dietary fibre and fatty acids in chronic obstructive pulmonary disease risk and progression: a systematic review

    Article • Respirology, December 2013, Wiley

    Harry Gosker

  23. Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease

    Article • The International Journal of Biochemistry & Cell Biology, October 2013, Elsevier

    Harry Gosker

  24. Metabolic and Structural Changes in Lower-Limb Skeletal Muscle Following Neuromuscular Electrical Stimulation: A Systematic Review

    Article • PLoS ONE, September 2013, PLOS

    Harry Gosker

  25. Reference values for vastus lateralis fiber type proportions and fiber size

    Article • Journal of Applied Physiology, September 2013, American Physiological Society

    Harry Gosker

  26. Heterogeneity of quadriceps muscle phenotype in chronic obstructive pulmonary disease (Copd); implications for stratified medicine?

    Article • Muscle & Nerve, August 2013, Wiley

    Harry Gosker

  27. Regulation of skeletal muscle oxidative phenotype by classical NF-κB signalling

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2013, Elsevier

    Harry Gosker

  28. Characterization of the inflammatory and metabolic profile of adipose tissue in a mouse model of chronic hypoxia

    Article • Journal of Applied Physiology, June 2013, American Physiological Society

    Harry Gosker

  29. Chronic obstructive pulmonary disease patient journey

    Article • Current Opinion in Clinical Nutrition & Metabolic Care, May 2013, Wolters Kluwer Health

    Harry Gosker

  30. Loss of quadriceps muscle oxidative phenotype and decreased endurance in patients with mild-to-moderate COPD

    Article • Journal of Applied Physiology, May 2013, American Physiological Society

    Harry Gosker

  31. The mechanisms of cachexia underlying muscle dysfunction in COPD

    Article • Journal of Applied Physiology, May 2013, American Physiological Society

    Harry Gosker

  32. Central Fat and Peripheral Muscle

    Article • American Journal of Respiratory and Critical Care Medicine, January 2013, American Thoracic Society

    Harry Gosker

  33. Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

    Article • Respiratory Research, January 2013, Springer Science + Business Media

    Harry Gosker

  34. Pathways associated with reduced quadriceps oxidative fibres and endurance in COPD

    Article • European Respiratory Journal, December 2012, European Respiratory Society (ERS)

    Harry Gosker

  35. The influence of abdominal visceral fat on inflammatory pathways and mortality risk in obstructive lung disease

    Article • American Journal of Clinical Nutrition, July 2012, Oxford University Press (OUP)

    Harry Gosker

  36. Low-grade adipose tissue inflammation in patients with mild-to-moderate chronic obstructive pulmonary disease

    Article • American Journal of Clinical Nutrition, November 2011, Oxford University Press (OUP)

    Harry Gosker

  37. Hypoxia and muscle maintenance regulation

    Article • Current Opinion in Clinical Nutrition & Metabolic Care, November 2011, Wolters Kluwer Health

    Harry Gosker

  38. Is age-related decline in lean mass and physical function accelerated by obstructive lung disease or smoking?

    Article • Thorax, July 2011, BMJ

    Harry Gosker

  39. Diabetes and Lung Function: Response

    Article • CHEST Journal, January 2011, Elsevier

    Harry Gosker

  40. TNF-  impairs regulation of muscle oxidative phenotype: implications for cachexia?

    Article • The FASEB Journal, August 2010, Federation of American Societies For Experimental Biology (FASEB)

    Harry Gosker

  41. Pulmonary Function in Diabetes

    Article • CHEST Journal, August 2010, Elsevier

    Harry Gosker

  42. Regulation of mitochondrial biogenesis during myogenesis

    Article • Molecular and Cellular Endocrinology, February 2010, Elsevier

    Harry Gosker

  43. The pathophysiology of cachexia in chronic obstructive pulmonary disease

    Article • Current Opinion in Supportive and Palliative Care, December 2009, Wolters Kluwer Health

    Harry Gosker

  44. The prevalence of quadriceps weakness in COPD and the relationship with disease severity

    Article • European Respiratory Journal, November 2009, European Respiratory Society (ERS)

    Harry Gosker

  45. Systemic and Pulmonary Oxidative Stress After Single-Leg Exercise in COPD

    Article • CHEST Journal, November 2009, Elsevier

    Harry Gosker

  46. PPARγ inhibits NF-κB-dependent transcriptional activation in skeletal muscle

    Article • AJP Endocrinology and Metabolism, July 2009, American Physiological Society

    Harry Gosker

  47. Extrapulmonary Manifestations of Chronic Obstructive Pulmonary Disease in a Mouse Model of Chronic Cigarette Smoke Exposure

    Article • American Journal of Respiratory Cell and Molecular Biology, June 2009, American Thoracic Society

    Harry Gosker

  48. Quadriceps muscle strength in scoliosis

    Article • European Respiratory Journal, May 2009, European Respiratory Society (ERS)

    Harry Gosker

  49. The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles vs. lower limb muscle dysfunction vs. dynamic hyperinflation

    Article • Journal of Applied Physiology, August 2008, American Physiological Society

    Harry Gosker

  50. Metabolic and functional effects of glutamate intake in patients with chronic obstructive pulmonary disease (COPD)

    Article • Clinical Nutrition, June 2008, Elsevier

    Harry Gosker

  51. Fatigued muscles in COPD but no finishing line in sight

    Article • European Respiratory Journal, April 2008, European Respiratory Society (ERS)

    Harry Gosker

  52. Peroxisome proliferator-activated receptors: a therapeutic target in COPD?

    Article • European Respiratory Journal, March 2008, European Respiratory Society (ERS)

    Harry Gosker

  53. "REDUCED MITOCHONDRIAL DENSITY IN THE VASTUS LATERALIS MUSCLE OF PATIENTS WITH COPD". H.R. GOSKER, M.K.C. HESSELINK, H. DUIMEL, K.A. WARD AND A.M.W.J. SCHOLS. EUR RESPIR J 2007; 30: 73 79.

    Article • European Respiratory Journal, October 2007, European Respiratory Society (ERS)

    Harry Gosker

  54. Cytokine profile in quadriceps muscles of patients with severe COPD

    Article • Thorax, September 2007, BMJ

    Harry Gosker

  55. A novel technique for nonvolitional assessment of quadriceps muscle endurance in humans

    Article • Journal of Applied Physiology, September 2007, American Physiological Society

    Harry Gosker

  56. Muscle Metabolic Modulation by Chronic Hypoxia

    Article • Journal of Proteome Research, September 2007, American Chemical Society (ACS)

    Harry Gosker

  57. Systemic Inflammation and Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease: State of the Art and Novel Insights in Regulation of Muscle Plasticity

    Article • Clinics in Chest Medicine, September 2007, Elsevier

    Harry Gosker

  58. Peroxisome proliferator-activated receptor expression is reduced in skeletal muscle in COPD

    Article • European Respiratory Journal, August 2007, European Respiratory Society (ERS)

    Harry Gosker

  59. Muscle fibre type shifting in the vastus lateralis of patients with COPD is associated with disease severity: a systematic review and meta-analysis

    Article • Thorax, May 2007, BMJ

    Harry Gosker

  60. The Functional, Metabolic, and Anabolic Responses to Exercise Training in Renal Transplant and Hemodialysis Patients

    Article • Transplantation, April 2007, Wolters Kluwer Health

    Harry Gosker

  61. Reduced mitochondrial density in the vastus lateralis muscle of patients with COPD

    Article • European Respiratory Journal, March 2007, European Respiratory Society (ERS)

    Harry Gosker

  62. Exercise training restores uncoupling protein-3 content in limb muscles of patients with chronic obstructive pulmonary disease

    Article • AJP Endocrinology and Metabolism, May 2006, American Physiological Society

    Harry Gosker

  63. Altered antioxidant status in peripheral skeletal muscle of patients with COPD

    Article • Respiratory Medicine, January 2005, Elsevier

    Professor Guido R Haenen, Harry Gosker

  64. Myopathological features in skeletal muscle of patients with chronic obstructive pulmonary disease

    Article • European Respiratory Journal, August 2003, European Respiratory Society (ERS)

    Harry Gosker

  65. Uncoupling protein‐3 content is decreased in peripheral skeletal muscle of patients with COPD

    Article • European Respiratory Journal, July 2003, European Respiratory Society (ERS)

    Harry Gosker

  66. Striking Similarities in Systemic Factors Contributing to Decreased Exercise Capacity in Patients With Severe Chronic Heart Failure or COPD

    Article • CHEST Journal, May 2003, Elsevier

    Harry Gosker

  67. Skeletal muscle fibre-type shifting and metabolic profile in patients with chronic obstructive pulmonary disease

    Article • European Respiratory Journal, April 2002, European Respiratory Society (ERS)

    Harry Gosker

  68. Muscle metabolic status in patients with severe COPD with and without long-term prednisolone

    Article • European Respiratory Journal, August 2000, European Respiratory Society (ERS)

    Harry Gosker

  69. Inhibition of Preprotein Translocation and Reversion of the Membrane Inserted State of SecA by a Carboxyl Terminus Binding MAb†

    Article • Biochemistry, July 1997, American Chemical Society (ACS)

    Harry Gosker