All Stories

  1. Immunonutrition in Acute Geriatric Care: Clinical Outcomes, Inflammatory Profiles, and Immune Responses
  2. Impact of endocrine disruptors on peripheral blood mononuclear cells in vitro: role of gender
  3. Differences in the Expression Levels of SARS-CoV-2 Spike Protein in Cells Treated with mRNA-Based COVID-19 Vaccines: A Study on Vaccines from the Real World
  4. Overexpression of Potential Markers of Regulatory and Exhausted CD8+ T Cells in the Peripheral Blood Mononuclear Cells of Patients with B-Acute Lymphoblastic Leukemia
  5. Association of GILZ with MUC2, TLR2, and TLR4 in Inflammatory Bowel Disease
  6. Diagnostic performance of the Bladder EpiCheck methylation test and photodynamic diagnosis-guided cystoscopy in the surveillance of high-risk non-muscle invasive bladder cancer: A single centre, prospective, blinded clinical trial
  7. Validation in an Independent Cohort of MiR-122, MiR-1271, and MiR-15b as Urinary Biomarkers for the Potential Early Diagnosis of Clear Cell Renal Cell Carcinoma
  8. Cardiovascular, neurological, and pulmonary events following vaccination with the BNT162b2, ChAdOx1 nCoV-19, and Ad26.COV2.S vaccines: An analysis of European data
  9. Blood clots and bleeding events following BNT162b2 and ChAdOx1 nCoV-19 vaccine: An analysis of European data
  10. Immune and Nervous Systems Interaction in Endocrine Disruptors Toxicity: The Case of Atrazine
  11. IgG4 induces tolerogenic M2-like macrophages and correlates with disease progression in colon cancer
  12. Detection of urinary miRNAs for diagnosis of clear cell renal cell carcinoma
  13. Immune modulation via T regulatory cell enhancement: disease‐modifying therapies for autoimmunity and their potential for chronic allergic and inflammatory diseases – An EAACI position paper of the Task Force on Immunopharmacology (TIPCO)
  14. Expansion of regulatory T cells prevents type 1 diabetes onset by inhibiting islet destruction
  15. Identification of 15 T Cell Restricted Genes Evaluates T Cell Infiltration of Human Healthy Tissues and Cancers and Shows Prognostic and Predictive Potential
  16. Evaluation of potential targets for ADCC induction against regulatory T cells in renal cell carcinoma
  17. The antibody frequently used to stain human GITR, does not bind GITR, leading to misleading results.
  18. The first‐generation phosphodiesterase 5 inhibitors and their pharmacokinetic issue
  19. ENGINEERED ALGINATE MICROCAPSULES FOR MOLECULAR THERAPY TROUGH BIOLOGIC SECRETING CELLS
  20. Context-Dependent Effect of Glucocorticoids on the Proliferation, Differentiation, and Apoptosis of Regulatory T Cells: A Review of the Empirical Evidence and Clinical Applications
  21. Beta-carotene, telomerase activity and Alzheimer’s disease in old age subjects
  22. Telomeres Increasingly Develop Aberrant Structures in Aging Humans
  23. Comparing biologicals and small molecule drug therapies for chronic respiratory diseases
  24. GITR is an interesting target for immunotherapy of cancers, infection and autoimmune diseases
  25. Triggering of GITR expands a subset of regulatory T cells and prevents diabetes development in mice
  26. Use of regulatory T cells to treat autoimmune diseases and prevent GVHD in murine models and humans
  27. Regulatory T cells (Tregs) expressing specific Treg markers that infiltrate 9 types of human cancers
  28. The Proinflammatory Cytokine GITRL Contributes to TRAIL-mediated Neurotoxicity in the HCN-2 Human Neuronal Cell Line
  29. Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy
  30. The role of GITR single-positive cells in immune homeostasis
  31. GITR: A Modulator of Regulatory and Effector T-Cell Activity, Crucial in Tumour Rejection and Autoimmune Diseases
  32. Modulation of tumor immunity: a patent evaluation of WO2015026684A1
  33. Are we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?
  34. GITR+ regulatory T cells in the treatment of autoimmune diseases
  35. A focused Real Time PCR strategy to determine GILZ expression in mouse tissues
  36. Glucocorticoid-Induced Tumour Necrosis Factor Receptor-Related Protein: A Key Marker of Functional Regulatory T Cells
  37. The Clinical Pharmacology of Past, Present, and Future Glucocorticoids
  38. The Molecular and Cellular Mechanisms Responsible for the Anti-inflammatory and Immunosuppressive Effects of Glucocorticoids
  39. Expansion of regulatory GITR+CD25low/-CD4+ T cells in systemic lupus erythematosus patients
  40. L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells
  41. Transcriptional regulation of kinases downstream of the T cell receptor: another immunomodulatory mechanism of glucocorticoids
  42. Eicosapentaenoic Acid Activates RAS/ERK/C/EBPβ Pathway through H-Ras Intron 1 CpG Island Demethylation in U937 Leukemia Cells
  43. Glucocorticoid-Induced Tumor Necrosis Factor Receptor Family-Related Ligand Triggering Upregulates Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 and Promotes Leukocyte Adhesion
  44. Characterization of a new regulatory CD4+ T cell subset in primary Sjogren's syndrome
  45. L-GILZ forms a complex with p53 and mdm2 and suppresses tumor growth through p53 activation
  46. Expansion of CD4+CD25-GITR+ regulatory T-cell subset in the peripheral blood of patients with primary Sjögren's syndrome: correlation with disease activity
  47. Mechanisms of the anti-inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways
  48. The intracellular portion of GITR enhances NGF-promoted neurite growth through an inverse modulation of Erk and NF-κB signalling
  49. Pharmacological modulation of GITRL/GITR system: therapeutic perspectives
  50. CD8+T Cells: GITR Matters
  51. Balance between Regulatory T and Th17 Cells in Systemic Lupus Erythematosus: The Old and the New
  52. GITR Gene Deletion and GITR-Fc Soluble Protein Administration Inhibit Multiple Organ Failure Induced by Zymosan
  53. CD4+CD25lowGITR+ cells: A novel human CD4+ T-cell population with regulatory activity
  54. Eicosapentaenoic Acid Demethylates a Single CpG That Mediates Expression of Tumor Suppressor CCAAT/Enhancer-binding Protein δ in U937 Leukemia Cells
  55. Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity
  56. The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice
  57. Effect of dietary saturated fatty acids on HNF-4α DNA binding activity and ApoCIII mRNA in sedentary rat liver
  58. Role of regulatory T cells in rheumatoid arthritis: facts and hypothesis
  59. Neutralization of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Reduces Spinal Cord Injury Damage in Mice
  60. Identification of regulatory T cells in systemic lupus erythematosus
  61. GITR: A Modulator of Immune Response and Inflammation
  62. The GITRL–GITR system alters TLR-4 expression on DC during fungal infection
  63. Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity
  64. Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related (GITR)-Fc Fusion Protein Inhibits GITR Triggering and Protects from the Inflammatory Response after Spinal Cord Injury
  65. Peroxisome Proliferator-Activated Receptor-α Contributes to the Anti-Inflammatory Activity of Glucocorticoids
  66. Glucocorticoid-Induced TNFR-Related Protein Lowers the Threshold of CD28 Costimulation in CD8+ T Cells
  67. Modulation of Acute and Chronic Inflammation of the Lung by GITR and its Ligand
  68. GITR/GITRL: More than an effector T cell co-stimulatory system
  69. Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
  70. GITR-GITRL System, A Novel Player in Shock and Inflammation
  71. Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation
  72. Interaction of CTSD and A2M polymorphisms in the risk for Alzheimer's disease
  73. Modulation of Pro- and Antiapoptotic Molecules in Double-Positive (CD4+CD8+) Thymocytes following Dexamethasone Treatment
  74. Proinflammatory Role of Glucocorticoid-Induced TNF Receptor-Related Gene in Acute Lung Inflammation
  75. Dietary PUFA modulate the expression of proliferation and differentiation markers in Morris 3924A hepatoma cells
  76. The Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related Gene Modulates the Response to Candida albicans Infection
  77. GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily
  78. Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock
  79. Frontline: GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations
  80. Dietary α-linolenic acid reduces COX-2 expression and induces apoptosis of hepatoma cells
  81. Cathepsin D Polymorphism in Italian Elderly Subjects with Sporadic Late-Onset Alzheimer’s Disease
  82. Enhanced expression of hepatic lipogenic enzymes in an animal model of sedentariness
  83. GITR interacts with the pro-apoptotic protein Siva and induces apoptosis
  84. Oxidative Stress and Apoptosis in Immune Diseases
  85. Role of GITR in activation response of T lymphocytes
  86. Gene Structure and Chromosomal Assignment of Mouse GITR, a Member of the Tumor Necrosis Factor/Nerve Growth Factor Receptor Family
  87. Identification of three novel mRNA splice variants of GITR
  88. Design and Synthesis of Modified Quinolones as Antitumoral Acridones
  89. Angiotensin converting enzyme deletion allele in different kinds of dementia disorders
  90. Antitumor activity of 2,2′-bipyridyl-6-carbothioamide: a ribonucleotide reductase inhibitor
  91. Apolipoprotein-E genotype in normal aging, age-associated memory impairment, Alzheimer's disease and vascular dementia patients
  92. A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis
  93. Short-Term Dexamethasone Treatment Modulates the Expression of the Murine TCRζ Gene Locus
  94. Dexamethasone modulates CD2 expression
  95. The 2,2′-Bipyridyl-6-carbothioamide copper (II) complex differs from the iron (II) complex in its biochemical effects in tumor cells, suggesting possible differences in the mechanism leading to cytotoxicity
  96. Ribonucleotide reductase inhibitors: new strategies for cancer chemotherapy
  97. Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogs. Synthesis, Structure, Antitumor Activity, and Interactions with Inosine Monophosphate Dehydrogenase
  98. T cell receptor ι an alternatively spliced product of the T cell receptor ζ gene
  99. Effect of dexamethasone on TCRζ gene expression
  100. Dexamethasone inhibits TCR/CD3 complex expression
  101. Chelating agents as potential antitumorals. 2-quinolylhydrazones and bis-2-quinolylhydrazones. I
  102. Dexamethasone and interleukins modulate apoptosis of murine thymocytes and peripheral T-lymphocytes
  103. 8-Aza Analogues of Deaza Purine Nucleosides. Synthesis and Biological Evaluation of 8-Aza-1-deazaadenosine and 2′-Deoxy-8-aza-1-deazaadenosine
  104. Synthesis and Evaluation of Anti-HIV-1 and Antitumor Activity of 2′,3′-didehydro-2′,3′-dideoxy-3-deazaadenosine, 2′,3′-dideoxy-3-Deazaadenosine and Some 2′,3′-dideoxy-3-deaza-adenosine 5′-dialkyl Phosphates1
  105. Synthesis and antitumor activity of 2-.beta.-D-ribofuranosyloxazole-4-carboxamide (oxazofurin)
  106. Implications and problems in analysing cytotoxic activity of hydroxyurea in combination with a potential inhibitor of ribonucleotide reductase*1
  107. Implications and problems in analysing cytotoxic activity of hydroxyurea in combination with a potential inhibitor of ribonucleotide reductase
  108. Early evaluation of a new 2,2′-bipyridyl derivative with potential inhibitory activity on the ribonucleotide reductase enzyme
  109. 3,7-Dideazapurine nucleosides. Synthesis and antitumor activity of 1-deazatubercidin and 2-chloro-2'-deoxy-3,7-dideazaadenosine