All Stories

  1. Exploring the Role of Platelets in Virus-Induced Inflammatory Demyelinating Disease and Myocarditis

    Article • International Journal of Molecular Sciences, March 2024, MDPI AG

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  2. Bryostatin-1 Attenuates Ischemia-Elicited Neutrophil Transmigration and Ameliorates Graft Injury after Kidney Transplantation

    Article • Cells, March 2022, MDPI AG

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  3. The Spectrum of Acute Cerebrovascular Disease in Patients with COVID-19

    Article • Biomedicines, February 2022, MDPI AG

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  4. Neutrophils and Platelets: Immune Soldiers Fighting Together in Stroke Pathophysiology

    Article • Biomedicines, December 2021, MDPI AG

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  5. Thromboinflammation in COVID‐19: The Clot Thickens

    Article • British Journal of Pharmacology, June 2021, Wiley

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  6. Thromboinflammation in COVID-19: The Clot Thickens

    Article • April 2021, Authorea, Inc.

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  7. The impact of thrombo‐inflammation on the cerebral microcirculation

    Article • Microcirculation, March 2021, Wiley

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  8. Targeting the AnxA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease

    Article • Blood, March 2021, American Society of Hematology

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  9. Targeting AnxA1/Formyl Peptide Receptor 2 Pathway Affords Protection against Pathological Thrombo-Inflammation

    Article • Cells, November 2020, MDPI AG

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  10. Targeting of Formyl Peptide Receptor 2 for in vivo imaging of acute vascular inflammation

    Article • Theranostics, January 2020, Ivyspring International Publisher

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  11. Endogenous Specialized Proresolving Mediator Profiles in a Novel Experimental Model of Lymphatic Obstruction and Intestinal Inflammation in African Green Monkeys

    Article • American Journal Of Pathology, October 2019, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  12. Therapeutic strategy for stroke

    Article • Circulation, July 2019, Wolters Kluwer Health

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  13. Correction to: Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation

    Article • Circulation, July 2019, Wolters Kluwer Health

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  14. Dynamic gut microbiome changes following regional intestinal lymphatic obstruction in primates

    Article • Pathophysiology, June 2019, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  15. Potential therapeutic roles of stem cells in ischemia-reperfusion injury

    Article • Stem Cell Research, May 2019, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  16. Ischemia-Reperfusion Injury in Sickle Cell Disease

    Article • American Journal Of Pathology, April 2019, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  17. Novel Role of T Cells and IL-6 (Interleukin-6) in Angiotensin II–Induced Microvascular Dysfunction

    Article • Hypertension, April 2019, Wolters Kluwer Health

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  18. Development, characterisation andin vitroevaluation of lanthanide-based FPR2/ALX-targeted imaging probes

    Article • Dalton Transactions, January 2019, Royal Society of Chemistry

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  19. IL-1β reduces cardiac lymphatic muscle contraction via COX-2 and PGE2 induction: Potential role in myocarditis

    Article • Biomedicine & Pharmacotherapy, November 2018, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins, Professor Ikuo Tsunoda

  20. The isothiocyanate sulforaphane modulates platelet function and protects against cerebral thrombotic dysfunction

    Article • British Journal of Pharmacology, July 2018, Wiley

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  21. The effect of high blood pressure on the immune system

    Article • The FASEB Journal, June 2018, Federation of American Societies For Experimental Biology (FASEB)

    Professor D. Neil Granger, Felicity N.E. Gavins, Alper Yildirim, Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  22. Therapeutic Potential of Annexin A1 in Ischemia Reperfusion Injury

    Article • International Journal of Molecular Sciences, April 2018, MDPI AG

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  23. Metallothionein I as a direct link between therapeutic hematopoietic stem/progenitor cells and cerebral protection in stroke

    Article • The FASEB Journal, January 2018, Federation of American Societies For Experimental Biology (FASEB)

    Professor Ikuo Tsunoda, Felicity N.E. Gavins, Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  24. Sickle cell disease: a malady beyond a hemoglobin defect in cerebrovascular disease

    Article • Expert Review of Hematology, December 2017, Taylor & Francis

    Felicity N.E. Gavins, Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  25. Non-celiac gluten sensitivity: All wheat attack is not celiac

    Article • World Journal of Gastroenterology, October 2017, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  26. Mast cells mediate early neutrophil recruitment and exhibit anti-inflammatory propertiesviathe formyl peptide receptor 2/lipoxin A4receptor

    Article • British Journal of Pharmacology, June 2017, Wiley

    Felicity N.E. Gavins, Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  27. Downregulation of CX3CR1 ameliorates experimental colitis: evidence for CX3CL1-CX3CR1-mediated immune cell recruitment

    Article • International Journal of Colorectal Disease, December 2016, Springer Science + Business Media

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  28. Surgical Approach for Middle Cerebral Artery Occlusion and Reperfusion Induced Stroke in Mice

    Article • Journal of Visualized Experiments, October 2016, MyJove Corporation

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  29. Sulforaphane induces neurovascular protection against a systemic inflammatory challenge via both Nrf2-dependent and independent pathways

    Article • Vascular Pharmacology, October 2016, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  30. A Critical Role for Monocytes/Macrophages During Intestinal Inflammation-associated Lymphangiogenesis

    Article • Inflammatory Bowel Diseases, June 2016, Oxford University Press (OUP)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins, Professor Ikuo Tsunoda

  31. Formyl-Peptide Receptor 2/3/Lipoxin A 4 Receptor Regulates Neutrophil-Platelet Aggregation and Attenuates Cerebral Inflammation

    Article • Circulation, May 2016, Wolters Kluwer Health

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  32. Modeling Ischemic Stroke In Vitro: Status Quo and Future Perspectives

    Article • Stroke, February 2016, Wolters Kluwer Health

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  33. Both MC 1 and MC 3 Receptors Provide Protection From Cerebral Ischemia-Reperfusion–Induced Neutrophil Recruitment

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2015, Wolters Kluwer Health

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  34. IL-1β reduces tonic contraction of mesenteric lymphatic muscle cells, with the involvement of cycloxygenase-2 and prostaglandin E2

    Article • British Journal of Pharmacology, July 2015, Wiley

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins, Professor Ikuo Tsunoda

  35. Critical differences between two classical surgical approaches for middle cerebral artery occlusion-induced stroke in mice

    Article • Journal of Neuroscience Methods, July 2015, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  36. Cell Tracking Technologies for Acute Ischemic Brain Injury

    Article • Journal of Cerebral Blood Flow & Metabolism, May 2015, SAGE Publications

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  37. Targeting the annexin 1-formyl peptide receptor 2/ALX pathway affords protection against bacterial LPS-induced pathologic changes in the murine adrenal cortex

    Article • The FASEB Journal, March 2015, Federation of American Societies For Experimental Biology (FASEB)

    Professor Julia Clare Buckingham, Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  38. Targeting formyl peptide receptor 2 reduces leukocyte-endothelial interactions in a murine model of stroke

    Article • The FASEB Journal, February 2015, Federation of American Societies For Experimental Biology (FASEB)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  39. 99mTc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation

    Article • Dalton Transactions, January 2015, Royal Society of Chemistry

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  40. PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression

    Article • Blood, December 2014, American Society of Hematology

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  41. Ischemia-reperfusion Injury in Sickle Cell Anemia

    Article • Hematology/Oncology Clinics of North America, April 2014, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  42. ICAM-2 regulates vascular permeability and N-cadherin localization through ezrin-radixin-moesin (ERM) proteins and Rac-1 signalling

    Article • Cell Communication and Signaling, January 2014, Springer Science + Business Media

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  43. Role and interactions of annexin A1 and oestrogens in the manifestation of sexual dimorphisms in cerebral and systemic inflammation

    Article • British Journal of Pharmacology, May 2013, Wiley

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  44. Phytochemicals: Countering risk factors and pathological responses associated with ischaemia reperfusion injury

    Article • Pharmacology & Therapeutics, April 2013, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  45. Gd3+cFLFLFK conjugate for MRI: a targeted contrast agent for FPR1 in inflammation

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  46. Intravital microscopy: new insights into cellular interactions

    Article • Current Opinion in Pharmacology, October 2012, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  47. New technologies: only a snapshot, but look how far we have come!

    Article • Current Opinion in Pharmacology, October 2012, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  48. Leukocyte recruitment in the brain in sepsis: involvement of the annexin 1-FPR2/ALX anti-inflammatory system

    Article • The FASEB Journal, September 2012, Federation of American Societies For Experimental Biology (FASEB)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  49. The peritoneal tumour microenvironment of high-grade serous ovarian cancer

    Article • The Journal of Pathology, April 2012, Wiley

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  50. The potential of stem cell therapy for stroke: is PISCES the sign?

    Article • The FASEB Journal, March 2012, Federation of American Societies For Experimental Biology (FASEB)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  51. Annexin A1 and the regulation of innate and adaptive immunity

    Article • Frontiers in Immunology, January 2012, Frontiers

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  52. Modeling inflammation and microvascular dysfunction

    Article • Annals of the New York Academy of Sciences, December 2011, Wiley

    Felicity N.E. Gavins, Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  53. Mechanisms of enhanced thrombus formation in cerebral microvessels of mice expressing hemoglobin-S

    Article • Blood, April 2011, American Society of Hematology

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  54. Microvascular thrombosis and CD40/CD40L signaling

    Article • Journal of Thrombosis and Haemostasis, March 2011, Wiley

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  55. Targeting the melanocortin receptor system for anti-stroke therapy

    Article • Trends in Pharmacological Sciences, February 2011, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  56. Are formyl peptide receptors novel targets for therapeutic intervention in ischaemia–reperfusion injury?

    Article • Trends in Pharmacological Sciences, June 2010, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  57. Troubleshooting methods: Using intravital microscopy in drug research

    Article • Journal of Pharmacological and Toxicological Methods, March 2010, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  58. Amcinonide

    Article • January 2010, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  59. Corticosterone

    Article • January 2009, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  60. Annexin A1 and the formyl peptide receptor family: neuroendocrine and metabolic aspects

    Article • Current Opinion in Pharmacology, December 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  61. Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion

    Article • The FASEB Journal, August 2008, Federation of American Societies For Experimental Biology (FASEB)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  62. Annexin A1 in the brain – undiscovered roles?

    Article • Trends in Pharmacological Sciences, March 2008, Elsevier

    Dr Simon McArthur, Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  63. Budesonide

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  64. Fluprednisolone

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  65. Dexamethasone

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  66. Cortisone

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  67. Fluocortolone

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  68. Clobetasone

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  69. Clobetasol

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  70. Deflazacort

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  71. Difluprednate

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  72. Halobetasol

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  73. Halcinonide

    Article • January 2008, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  74. Stem/Progenitor Cell-Like Properties of Desmoglein 3dimCells in Primary and Immortalized Keratinocyte Lines

    Article • Stem Cells, May 2007, Wiley

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  75. Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation

    Article • The FASEB Journal, February 2007, Federation of American Societies For Experimental Biology (FASEB)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins, Prof Jesmond Dalli

  76. 11 Deoxycortisol

    Article • January 2007, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  77. Fluticasone

    Article • January 2007, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  78. The Evolving Paradigm for Blood Cell-Endothelial Cell Interactions in the Cerebral Microcirculation

    Article • Microcirculation, January 2007, Wiley

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  79. [d-Trp8]-γ-Melanocyte-Stimulating Hormone Exhibits Anti-Inflammatory Efficacy in Mice Bearing a Nonfunctional MC1R (Recessive Yellow e/e Mouse)

    Article • Molecular Pharmacology, September 2006, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  80. Annexin 1 and Melanocortin Peptide Therapy for Protection Against Ischaemic-Reperfusion Damage in the Heart

    Article • The Scientific World JOURNAL, January 2006, Hindawi Publishing Corporation

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  81. A twist in anti-inflammation: Annexin 1 acts via the lipoxin A4 receptor

    Article • Prostaglandins Leukotrienes and Essential Fatty Acids, September 2005, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  82. Formyl-peptide receptor is not involved in the protection afforded by annexin 1 in murine acute myocardial infarct

    Article • The FASEB Journal, October 2004, Federation of American Societies For Experimental Biology (FASEB)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  83. Intravital microscopy for the study of mouse microcirculation in anti-inflammatory drug research: Focus on the mesentery and cremaster preparations

    Article • Journal of Pharmacological and Toxicological Methods, January 2004, Elsevier

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  84. Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms

    Article • Blood, May 2003, American Society of Hematology

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  85. Annexin 1: An Endogenous Anti-Inflammatory Protein

    Article • Physiology, April 2003, American Physiological Society

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  86. Redundancy of a Functional Melanocortin 1 Receptor in the Anti-inflammatory Actions of Melanocortin Peptides: Studies in the Recessive Yellow (e/e) Mouse Suggest an Important Role for Melanocortin 3 Receptor

    Article • The Journal of Immunology, March 2003, The American Association of Immunologists

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  87. Aberrant inflammation and resistance to glucocorticoids in Annexin 1-/- Mouse

    Article • The FASEB Journal, December 2002, Federation of American Societies For Experimental Biology (FASEB)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  88. Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action

    Article • The FASEB Journal, October 2001, Federation of American Societies For Experimental Biology (FASEB)

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins

  89. The Use of Lymphocyte Function–Associated Antigen (Lfa)-1–Deficient Mice to Determine the Role of Lfa-1, Mac-1, and α4 Integrin in the Inflammatory Response of Neutrophils

    Article • Journal of Experimental Medicine, July 2001, Rockefeller University Press

    Professor of Pharmacology & Royal Society Wolfson Fellow Felicity N. E. Gavins