All Stories

  1. Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators

    Article • Cell Chemical Biology, July 2017, Elsevier

    Dr Ellen L Berg

  2. Phenotypic chemical biology for predicting safety and efficacy

    Article • Drug Discovery Today Technologies, March 2017, Elsevier

    Dr Ellen L Berg

  3. Empirical drug discovery: a view from the proteome

    Article • Drug Discovery Today Technologies, March 2017, Elsevier

    Dr Ellen L Berg

  4. Complex Primary Human Cell Systems for Drug Discovery

    Article • December 2014, Royal Society of Chemistry

    Dr Ellen L Berg

  5. Elucidating adverse outcome pathways with phenotypic data from primary human cell systems

    Article • Toxicology Letters, September 2014, Elsevier

    Dr Ellen L Berg

  6. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms

    Article • Nature Biotechnology, May 2014, Springer Science + Business Media

    Dr Ellen L Berg, Dr Richard S Judson, Dr Keith Houck, Dr Nicole Kleinstreuer

  7. Consideration of the cellular microenvironment: Physiologically relevant co-culture systems in drug discovery

    Article • Advanced Drug Delivery Reviews, April 2014, Elsevier

    Dr Ellen L Berg

  8. S50. Proffered paper: Complex tumour microenvironment screening platform captures biological responses of cancer therapeutics

    Article • Journal for ImmunoTherapy of Cancer, March 2014, BMJ

    Dr Ellen L Berg

  9. Systems biology in drug discovery and development

    Article • Drug Discovery Today, February 2014, Elsevier

    Dr Ellen L Berg

  10. Building Predictive Models for Mechanism-of-Action Classification from Phenotypic Assay Data Sets

    Article • SLAS DISCOVERY, December 2013, Elsevier

    Dr Ellen L Berg

  11. Neoclassic Drug Discovery

    Article • SLAS DISCOVERY, December 2013, SAGE Publications

    Dr Ellen L Berg

  12. Regulation of IL-17A Production Is Distinct from IL-17F in a Primary Human Cell Co-culture Model of T Cell-Mediated B Cell Activation

    Article • PLoS ONE, March 2013, PLOS

    Dr Ellen L Berg

  13. Abstract 1093: BioMAP® profiling in primary human cell systems as a tool for drug discovery in inflammation and cancer

    Article • Cancer Research, April 2011, American Association for Cancer Research (AACR)

    Dr Ellen L Berg

  14. Chemical target and pathway toxicity mechanisms defined in primary human cell systems

    Article • Journal of Pharmacological and Toxicological Methods, January 2010, Elsevier

    Dr Sean Ekins, Dr Ellen L Berg

  15. Characterization of compound mechanisms and secondary activities by BioMAP analysis

    Article • Journal of Pharmacological and Toxicological Methods, January 2006, Elsevier

    Dr Ellen L Berg

  16. Biological complexity and drug discovery: a practical systems biology approach

    Article • Systems Biology, January 2005, the Institution of Engineering and Technology (the IET)

    Dr Ellen L Berg

  17. Systems biology in drug discovery

    Article • Nature Biotechnology, October 2004, Springer Science + Business Media

    Dr Ellen L Berg

  18. Rapid Structure-Activity and Selectivity Analysis of Kinase Inhibitors by BioMAP Analysis in Complex Human Primary Cell-Based Models

    Article • Assay and Drug Development Technologies, August 2004, Mary Ann Liebert Inc

    Dr Ellen L Berg

  19. Method for analyzing signaling networks in complex cellular systems

    Article • Proceedings of the National Academy of Sciences, January 2004, Proceedings of the National Academy of Sciences

    Dr Ellen L Berg

  20. A Direct Comparison of Selectin-Mediated Transient, Adhesive Events Using High Temporal Resolution

    Article • Biophysical Journal, December 1999, Elsevier

    Dr Ellen L Berg

  21. Epitope Mapping of Mouse Monoclonal Antibody EP-5C7 Which Neutralizes Both Human E- and P-selectin

    Article • Biochemical and Biophysical Research Communications, January 1998, Elsevier

    Dr Ellen L Berg

  22. Fine mapping of the epitopes of humanized anti-l-selectin monoclonal antibodies HuDREG-55 and HuDREG-200

    Article • Immunology Letters, November 1997, Elsevier

    Dr Ellen L Berg

  23. 4-07-19 E-selectin appears in non-ischemic tissue during experimental focal cerebral ischemia

    Article • Journal of the Neurological Sciences, September 1997, Elsevier

    Dr Ellen L Berg

  24. Vascular Adhesion Protein 1 (VAP-1) Mediates Lymphocyte Subtype-specific, Selectin-independent Recognition of Vascular Endothelium in Human Lymph Nodes

    Article • The Journal of Experimental Medicine, August 1997, Rockefeller University Press

    Dr Ellen L Berg

  25. PCR cloning of the cDNA encoding baboon l-selectin

    Article • Gene, November 1996, Elsevier

    Dr Ellen L Berg

  26. E-Selectin Appears in Nonischemic Tissue During Experimental Focal Cerebral Ischemia

    Article • Stroke, August 1996, Wolters Kluwer Health

    Dr Ellen L Berg

  27. Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier

    Article • Developmental Dynamics, April 1995, Wiley

    Dr Ellen L Berg

  28. Rolling of lymphocytes and neutrophils on peripheral node addressin and subsequent arrest on ICAM‐1 in shear flow

    Article • European Journal of Immunology, April 1995, Wiley

    Dr Ellen L Berg

  29. L-selectin-mediated lymphocyte rolling on MAdCAM-1

    Article • Nature, December 1993, Springer Science + Business Media

    Dr Ellen L Berg

  30. α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1

    Article • Cell, July 1993, Elsevier

    Dr Ellen L Berg

  31. Comparison of L-selectin and E-selectin ligand specificities: The L-selectin can bind the E-selectin ligands Sialyl Lex and Sialyl Lea

    Article • Biochemical and Biophysical Research Communications, April 1992, Elsevier

    Dr Ellen L Berg

  32. Vascular Addressins: Tissue Selective Endothelial Cell Adhesion Molecules for Lymphocyte Homing

    Article • January 1991, Elsevier

    Dr Ellen L Berg

  33. Homing Receptors in Lymphocyte, Neutrophil, and Monocyte Interaction with Endothelial Cells

    Article • January 1990, Springer Science + Business Media

    Dr Ellen L Berg

  34. INFLAMMATION-INDUCED ENDOTHELIAL CELL ADHESION TO LYMPHOCYTES, NEUTROPHILS, AND MONOCYTES

    Article • Transplantation, November 1989, Wolters Kluwer Health

    Dr Ellen L Berg

  35. Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors

    Article • Science, September 1989, American Association for the Advancement of Science

    Dr Ellen L Berg

  36. Homing Receptors and Vascular Addressins: Cell Adhesion Molecules that Direct Lymphocyte Traffic

    Article • Immunological Reviews, April 1989, Wiley

    Dr Ellen L Berg

  37. The mucosal vascular addressin is a tissue-specific endothelial cell adhesion molecule for circulating lymphocytes

    Article • Nature, January 1989, Springer Science + Business Media

    Dr Ellen L Berg

  38. Ly‐6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon‐gamma

    Article • European Journal of Immunology, November 1988, Wiley

    Dr Ellen L Berg

  39. A tissue-specific endothelial cell molecule involved in lymphocyte homing

    Article • Nature, January 1988, Springer Science + Business Media

    Dr Ellen L Berg