All Stories

  1. Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

    Article • Science Translational Medicine, April 2016, American Association for the Advancement of Science

    Dr Dominic De Nardo

  2. Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation

    Article • Science Translational Medicine, March 2016, American Association for the Advancement of Science

    Dr Dominic De Nardo

  3. Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use

    Article • Science Signaling, January 2016, American Association for the Advancement of Science

    Dr Dominic De Nardo

  4. ATF3 Is a Key Regulator of Macrophage IFN Responses

    Article • The Journal of Immunology, September 2015, The American Association of Immunologists

    Dr Dominic De Nardo

  5. Toll-like receptors: Activation, signalling and transcriptional modulation

    Article • Cytokine, August 2015, Elsevier

    Dr Dominic De Nardo

  6. Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β

    Article • The Journal of Experimental Medicine, May 2015, Rockefeller University Press

    Dr Dominic De Nardo

  7. The Inflammasomes and Autoinflammatory Syndromes

    Article • Annual Review of Pathology Mechanisms of Disease, January 2015, Annual Reviews

    Professor Eicke Latz, Dr Bernardo S Franklin, Dr Dominic De Nardo

  8. Optimization of transcription factor binding map accuracy utilizing knockout-mouse models

    Article • Nucleic Acids Research, November 2014, Oxford University Press (OUP)

    Dr Dominic De Nardo

  9. The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

    Article • Nature Immunology, June 2014, Nature

    Professor Eicke Latz, Dr Bernardo S Franklin, Dr Dominic De Nardo

  10. Interferon Regulatory Factor 6 Differentially Regulates Toll-like Receptor 2-dependent Chemokine Gene Expression in Epithelial Cells

    Article • Journal of Biological Chemistry, May 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Dominic De Nardo

  11. Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

    Article • Immunity, February 2014, Elsevier

    Professor Eicke Latz, Dr Dominic De Nardo

  12. Innate immunity

    Article • Current Opinion in Immunology, February 2014, Elsevier

    Dr Dominic De Nardo

  13. New Insights into Mechanisms Controlling the NLRP3 Inflammasome and Its Role in Lung Disease

    Article • American Journal Of Pathology, January 2014, Elsevier

    Professor Eicke Latz, Dr Dominic De Nardo

  14. High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3

    Article • Nature Immunology, December 2013, Springer Science + Business Media

    Professor Bryan R. G. Williams, Professor Eicke Latz, Dr Dominic De Nardo

  15. Inflammasomopathies: Diseases Linked to the NLRP3 Inflammasome

    Article • July 2012, World Scientific Pub Co Pte Lt

    Professor Eicke Latz, Dr Dominic De Nardo

  16. NLRP3 inflammasomes link inflammation and metabolic disease

    Article • Trends in Immunology, August 2011, Elsevier

    Professor Eicke Latz, Dr Dominic De Nardo

  17. Signaling Crosstalk during Sequential TLR4 and TLR9 Activation Amplifies the Inflammatory Response of Mouse Macrophages

    Article • The Journal of Immunology, November 2009, The American Association of Immunologists

    Dr Dominic De Nardo

  18. Regulation of IRAK-1 activation by its C-terminal domain

    Article • Cellular Signalling, May 2009, Elsevier

    Dr Dominic De Nardo

  19. Down-regulation of IRAK-4 is a component of LPS- and CpG DNA-induced tolerance in macrophages

    Article • Cellular Signalling, February 2009, Elsevier

    Dr Dominic De Nardo

  20. The Critical Role of the Colony-Stimulating Factor-1 Receptor in the Differentiation of Myeloblastic Leukemia Cells

    Article • Molecular Cancer Research, February 2008, American Association for Cancer Research (AACR)

    Dr Dominic De Nardo

  21. A Central Role for the Hsp90{middle dot}Cdc37 Molecular Chaperone Module in Interleukin-1 Receptor-associated-kinase-dependent Signaling by Toll-like Receptors

    Article • Journal of Biological Chemistry, January 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Dominic De Nardo