Professor Dietmar J. Manstein

All Stories

1. 
   Molecular mechanisms of hotspot variants in cytoskeletal β‐actin associated with Baraitser–Winter syndrome

   Article • FEBS Journal, February 2025, Wiley

   Professor Dietmar J. Manstein

2. 
   Abstract 4145767: Genetic impairment in myosin-5b related transport processes mediates cardiac dysfunction and sudden cardiac death

   Article • Circulation, November 2024, Wolters Kluwer Health

   Professor Dietmar J. Manstein

3. 
   Crystal structures of cables formed by the acetylated and unacetylated forms of the Schizosaccharomyces pombe tropomyosin orthologue TpmCdc8

   Article • Journal of Biological Chemistry, October 2024, Elsevier

   Dr Manuel H Taft, Professor Dietmar J. Manstein

4. 
   The Novel MYH9 Variant, c.1270C>G, p.Arg424Gly, Causes Epstein-Fechtner Syndrome by the Modification of Nonmuscular Myosin IIA Contraction

   Article • Journal of the American Society of Nephrology, October 2024, Wolters Kluwer Health

   Professor Dietmar J. Manstein

5. 
   Genomic and biological panoramas of non-muscle actinopathies

   Article • August 2024, Cold Spring Harbor Laboratory Press

   Professor Dietmar J. Manstein

6. 
   Motor properties of Myosin 5c are modulated by tropomyosin isoforms and inhibited by pentabromopseudilin

   Article • Frontiers in Physiology, March 2024, Frontiers

   Professor Dietmar J. Manstein

7. 
   Baraitser–Winter Syndrome Hotspot Mutation R196H in Cytoskeletal β–actin Reduces F–actin Stability and Perturbs Interaction with the Arp2/3 Complex

   Article • March 2024, Cold Spring Harbor Laboratory Press

   Professor Dietmar J. Manstein

8. 
   Biochemical characterization of cardiac α‐actin mutations A21V and D26N implicated in hypertrophic cardiomyopathy

   Article • Cytoskeleton, March 2024, Wiley

   Dr Manuel H Taft, Professor Dietmar J. Manstein

9. 
   The non-muscle actinopathy-associated mutation E334Q in cytoskeletal γ-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins

   Article • eLife, March 2024, eLife

   Dr Manuel H Taft, Professor Dietmar J. Manstein

10. 
    The non–muscle actinopathy–associated mutation E334Q in cytoskeletal γ–actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins

    Article • December 2023, eLife

    Dr Manuel H Taft, Professor Dietmar J. Manstein

11. 
    Abstracts from the 55th European Society of Human Genetics (ESHG) Conference

    Article • European Journal of Human Genetics, May 2023, Springer Science + Business Media

    Professor Dietmar J. Manstein

12. 
    Distinct actin–tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes

    Article • iScience, July 2022, Elsevier

    Dr Manuel H Taft, Professor Dietmar J. Manstein

13. 
    Frameshift mutation S368fs in the gene encoding cytoskeletal β-actin leads to ACTB-associated syndromic thrombocytopenia by impairing actin dynamics

    Article • European Journal of Cell Biology, April 2022, Elsevier

    Dr Manuel H Taft, Professor Dietmar J. Manstein

14. 
    Assessment of the Contribution of a Thermodynamic and Mechanical Destabilization of Myosin-Binding Protein C Domain C2 to the Pathomechanism of Hypertrophic Cardiomyopathy-Causing Double Mutation MYBPC3Δ25bp/D389V

    Article • International Journal of Molecular Sciences, November 2021, MDPI AG

    Dr Manuel H Taft, Professor Dietmar J. Manstein

15. 
    Assessment of the Contribution of a Thermodynamic and Mechanical Destabilization of Myosin–Binding Protein C Domain C2 to the Pathomechanism of Hypertrophic Cardiomyopathy–causing Double Mutation MYBPC3Δ25bp/D389V

    Article • October 2021, MDPI AG

    Dr Manuel H Taft, Professor Dietmar J. Manstein

16. 
    CORE-MD II: A fast, adaptive, and accurate enhanced sampling method

    Article • The Journal of Chemical Physics, September 2021, American Institute of Physics

    Professor Dietmar J. Manstein

17. 
    Improvement of image resolution by combining enhanced confocal microscopy and quantum dot triexciton imaging

    Article • FEBS Open Bio, July 2021, Wiley

    Professor Dietmar J. Manstein

18. 
    Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Professor Dietmar J. Manstein, Dr Manuel H Taft

19. 
    Structural and Biochemical Characterization of a Dye Decolorizing Peroxidase from Dictyostelium discoideum

    Article • June 2021, MDPI AG

    Dr Manuel H Taft, Professor Dietmar J. Manstein

20. 
    Allosteric modulation of cardiac myosin mechanics and kinetics by the conjugated omega‐7,9 trans‐fat rumenic acid

    Article • The Journal of Physiology, June 2021, Wiley

    Professor Dietmar J. Manstein, Dr Manuel H Taft

21. 
    Structural and Biochemical Characterization of a Dye Decolorizing Peroxidase from Dictyostelium discoideum

    Article • May 2021, MDPI AG

    Dr Manuel H Taft, Professor Dietmar J. Manstein

22. 
    Muscle myosin performance measured with a synthetic nanomachine reveals a class‐specific Ca 2+ ‐sensitivity of the frog myosin II isoform

    Article • The Journal of Physiology, January 2021, Wiley

    Dr Manuel H Taft, Professor Dietmar J. Manstein

23. 
    Mechanochemical properties of human myosin 1C are modulated by isoform-specific differences in the N-terminal extension

    Article • Journal of Biological Chemistry, November 2020, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Manuel H Taft, Professor Dietmar J. Manstein

24. 
    Myosin-18B Regulates Higher-Order Organization of the Cardiac Sarcomere through Thin Filament Cross-Linking and Thick Filament Dynamics

    Article • Cell Reports, September 2020, Elsevier

    Dr Manuel H Taft, Professor Dietmar J. Manstein

25. 
    Undefeated—Changing the phenamacril scaffold is not enough to beat resistant Fusarium

    Article • PLOS One, June 2020, PLOS

    Dr Manuel H Taft, Professor Dietmar J. Manstein

26. 
    Small Molecule Effectors of Myosin Function

    Article • January 2020, Springer Science + Business Media

    Professor Dietmar J. Manstein

27. 
    Unique structure and function of viral rhodopsins

    Article • Nature Communications, October 2019, Springer Science + Business Media

    Professor Dietmar J. Manstein

28. 
    Actin–tropomyosin distribution in non-muscle cells

    Article • Journal of Muscle Research and Cell Motility, May 2019, Springer Science + Business Media

    Professor Dietmar J. Manstein

29. 
    Phenamacril is a reversible and non-competitive inhibitor of Fusarium class I myosin

    Article • Journal of Biological Chemistry, November 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Dietmar J. Manstein, Dr Manuel H Taft

30. 
    Author Correction: Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia

    Article • Nature Communications, November 2018, Springer Science + Business Media

    Dr Manuel H Taft, Professor Dietmar J. Manstein

31. 
    Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia

    Article • Nature Communications, October 2018, Springer Science + Business Media

    Professor Dietmar J. Manstein, Dr Manuel H Taft

32. 
    Treatments targeting inotropy

    Article • European Heart Journal, October 2018, Oxford University Press (OUP)

    Professor Dietmar J. Manstein, Professor John GF Cleland

33. 
    Co-polymers of Actin and Tropomyosin Account for a Major Fraction of the Human Actin Cytoskeleton

    Article • Current Biology, July 2018, Elsevier

    Professor Dietmar J. Manstein, Dr Manuel H Taft

34. 
    Thrombocytopenia Microcephaly Syndrome - a novel phenotype associated with ACTB mutations

    Article • April 2018, Cold Spring Harbor Laboratory Press

    Professor Dietmar J. Manstein, Dr Manuel H Taft

35. 
    Mechanistic insights into the active site and allosteric communication pathways in human nonmuscle myosin-2C

    Article • eLife, December 2017, eLife

    Professor Dietmar J. Manstein

36. 
    Three mammalian tropomyosin isoforms have different regulatory effects on nonmuscle myosin-2B and filamentous β-actinin vitro

    Article • Journal of Biological Chemistry, November 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Dietmar J. Manstein, Dr Manuel H Taft

37. 
    Pink-beam serial crystallography

    Article • Nature Communications, November 2017, Springer Science + Business Media

    Professor Henry N Chapman, Professor Dietmar J. Manstein, Dr Manuel H Taft

38. 
    N-terminal splicing extensions of the humanMYO1Cgene fine-tune the kinetics of the three full-length myosin IC isoforms

    Article • Journal of Biological Chemistry, September 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Dietmar J. Manstein, Dr Manuel H Taft

39. 
    Inward H + pump xenorhodopsin: Mechanism and alternative optogenetic approach

    Article • Science Advances, September 2017, American Association for the Advancement of Science

    Professor Dietmar J. Manstein

40. 
    Structural and biochemical studies of sulphotransferase 18 from Arabidopsis thaliana explain its substrate specificity and reaction mechanism

    Article • Scientific Reports, June 2017, Nature

    Professor Dietmar J. Manstein

41. 
    Mechanistic Insights Into The Active Site And Allosteric Communication Pathways In Human Nonmuscle Myosin-2C

    Article • May 2017, Cold Spring Harbor Laboratory Press

    Professor Dietmar J. Manstein

42. 
    Tropomyosin Isoforms Specify Functionally Distinct Actin Filament Populations In Vitro

    Article • Current Biology, March 2017, Elsevier

    Professor Dietmar J. Manstein

43. 
    Myosin Motors: Structural Aspects and Functionality☆

    Article • January 2017, Elsevier

    Professor Dietmar J. Manstein

44. 
    Our muscle at near-atomic resolution - Cryo-EM structure of the F-actin-tropomyosin complex

    Article • December 2016, Wiley

    Professor Dietmar J. Manstein

45. 
    Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution

    Article • Nature, June 2016, Nature

    Professor Dietmar J. Manstein

46. 
    Datasets from a vapor diffusion mineral precipitation protocol for Dictyostelium stalks

    Article • Data in Brief, June 2016, Elsevier

    Professor Dietmar J. Manstein

47. 
    Tropomyosin-Mediated Regulation of Cytoplasmic Myosins

    Article • Traffic, May 2016, Wiley

    Professor Dietmar J. Manstein, Dr Daniel Mulvihill

48. 
    Load-dependent modulation of non-muscle myosin-2A function by tropomyosin 4.2

    Article • Scientific Reports, February 2016, Nature

    Professor Dietmar J. Manstein, Dr Manuel H Taft

49. 
    Structure of the F-Actin-Tropomyosin Complex Revealed by Electron Cryomicroscopy

    Article • Biophysical Journal, February 2016, Elsevier

    Professor Dietmar J. Manstein

50. 
    Arachidonic Acid Directly Binds and Activates Beta-Cardiac Myosin in the Regulated Cardiac Actomyosin Complex

    Article • Biophysical Journal, February 2016, Elsevier

    Professor Dietmar J. Manstein, Dr Manuel H Taft

51. 
    Crystal structure of the dynamin tetramer

    Article • Nature, August 2015, Nature

    Professor Dietmar J. Manstein

52. 
    The Activation Mechanism of 2′-5′-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity

    Article • Structure, May 2015, Elsevier

    Professor Dietmar J. Manstein

53. 
    Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion

    Article • Autophagy, December 2014, Taylor & Francis

    Professor Dietmar J. Manstein

54. 
    Structure of the F-actin–tropomyosin complex

    Article • Nature, December 2014, Springer Science + Business Media

    Professor Dietmar J. Manstein

55. 
    Crystal structure of the rigor-like human non-muscle myosin-2 motor domain

    Article • FEBS Letters, November 2014, Wiley

    Professor Dietmar J. Manstein

56. 
    Molecular mechanisms of disease-related human β-actin mutations p.R183W and p.E364K

    Article • FEBS Journal, October 2014, Wiley

    Professor Dietmar J. Manstein

57. 
    Silver(I)-Catalyzed Route to Pyrroles: Synthesis of Halogenated Pseudilins as Allosteric Inhibitors for Myosin ATPase and X-ray Crystal Structures of the Protein-Inhibitor Complexes (Eur. J. Org. Chem. 21/2014)

    Article • European Journal of Organic Chemistry, July 2014, Wiley

    Professor Dietmar J. Manstein

58. 
    Silver(I)‐Catalyzed Route to Pyrroles: Synthesis of Halogenated Pseudilins as Allosteric Inhibitors for Myosin ATPase and X‐ray Crystal Structures of the Protein–Inhibitor Complexes

    Article • European Journal of Organic Chemistry, May 2014, Wiley

    Professor Dietmar J. Manstein

59. 
    Crystal Structure of Human Myosin 1c—The Motor in GLUT4 Exocytosis: Implications for Ca2+ Regulation and 14-3-3 Binding

    Article • Journal of Molecular Biology, May 2014, Elsevier

    Professor Dietmar J. Manstein, Dr Manuel H Taft

60. 
    Small molecule-mediated refolding and activation of myosin motor function

    Article • eLife, February 2014, eLife

    Professor Dietmar J. Manstein, Dr Manuel H Taft

61. 
    Expression, purification and crystallization of a dye-decolourizing peroxidase from Dictyostelium discoideum

    Article • Acta Crystallographica Section F Structural Biology Communications, January 2014, International Union of Crystallography

    Professor Dietmar J. Manstein

62. 
    Human Myosin-18B - A Versatile Actin Binding Protein

    Article • Biophysical Journal, January 2014, Elsevier

    Professor Dietmar J. Manstein, Dr Manuel H Taft

63. 
    Structural and Functional Characterization of Nonmuscle Myosin-2B in the Presence of Regulated Actin Filaments

    Article • Biophysical Journal, January 2014, Elsevier

    Professor Dietmar J. Manstein, Dr Manuel H Taft

64. 
    Structural Basis of Myosin 1C Ca2+ Regulation

    Article • Biophysical Journal, January 2014, Elsevier

    Professor Dietmar J. Manstein, Dr Manuel H Taft

65. 
    Functional Characterization of Disease-Related Human β-Actin Mutants

    Article • Biophysical Journal, January 2014, Elsevier

    Professor Dietmar J. Manstein

66. 
    Myosin Structure, Allostery, and Mechano-Chemistry

    Article • Structure, November 2013, Elsevier

    Professor Dietmar J. Manstein

67. 
    Kinetic and Thermodynamic Analysis of the Light-induced Processes in Plant and Cyanobacterial Phytochromes

    Article • Biophysical Journal, November 2013, Elsevier

    Professor Dietmar J. Manstein

68. 
    Unconventional Human Myosin-18A

    Article • Journal of Biological Chemistry, August 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Manuel H Taft, Professor Dietmar J. Manstein

69. 
    Expression, purification, crystallization and preliminary X-ray crystallographic analysis of human myosin 1c in complex with calmodulin

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, August 2013, International Union of Crystallography

    Professor Dietmar J. Manstein

70. 
    Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML

    Article • Blood, August 2013, American Society of Hematology

    Professor Dietmar J. Manstein

71. 
    Distinct Functional Interactions between Actin Isoforms and Nonsarcomeric Myosins

    Article • PLOS One, July 2013, PLOS

    Professor Dietmar J. Manstein, Dr Manuel H Taft

72. 
    Functional Dissection of the Dictyostelium discoideum Dynamin B Mitochondrial Targeting Sequence

    Article • PLOS One, February 2013, PLOS

    Professor Dietmar J. Manstein

73. 
    Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 2)

    Article • August 2012, Protein Data Bank, Rutgers University

    Professor Dietmar J. Manstein

74. 
    Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 1)

    Article • August 2012, Protein Data Bank, Rutgers University

    Professor Dietmar J. Manstein

75. 
    Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 3)

    Article • August 2012, Protein Data Bank, Rutgers University

    Professor Dietmar J. Manstein

76. 
    Structure of bare F-actin filaments obtained from the same sample as the Actin-Tropomyosin-Myosin Complex

    Article • August 2012, Protein Data Bank, Rutgers University

    Professor Dietmar J. Manstein

77. 
    Kinetic properties and small‐molecule inhibition of human myosin‐6

    Article • FEBS Letters, July 2012, Wiley

    Professor Dietmar J. Manstein

78. 
    Structure of the Rigor Actin-Tropomyosin-Myosin Complex

    Article • Cell, July 2012, Elsevier

    Professor Dietmar J. Manstein

79. 
    Functional characterization of the human α-cardiac actin mutations Y166C and M305L involved in hypertrophic cardiomyopathy

    Article • Cellular and Molecular Life Sciences, May 2012, Springer Science + Business Media

    Professor Dietmar J. Manstein

80. 
    Nonmuscle myosin-2: mix and match

    Article • Cellular and Molecular Life Sciences, May 2012, Springer Science + Business Media

    Professor Dietmar J. Manstein

81. 
    EMD57033 Acts as a Pharmacological Chaperone Stabilizing and Activating Myosin Motor Activity

    Article • Biophysical Journal, January 2012, Elsevier

    Professor Dietmar J. Manstein, Dr Manuel H Taft

82. 
    Subnanometer Structure of the Actin/Myosin/Tropomyosin Complex

    Article • Biophysical Journal, January 2012, Elsevier

    Professor Dietmar J. Manstein

83. 
    Functional Characterization of Human Myosin-18A and its Interaction Partners

    Article • Biophysical Journal, January 2012, Elsevier

    Professor Dietmar J. Manstein, Dr Manuel H Taft

84. 
    4.8 Myosin Motors: Structural Aspects and Functionality

    Article • January 2012, Elsevier

    Professor Dietmar J. Manstein

85. 
    Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V

    Article • Journal of Biological Chemistry, August 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Dietmar J. Manstein

86. 
    Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2

    Article • July 2011, Protein Data Bank, Rutgers University

    Professor Dietmar J. Manstein

87. 
    Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2

    Article • July 2011, Protein Data Bank, Rutgers University

    Professor Dietmar J. Manstein

88. 
    Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2

    Article • July 2011, Protein Data Bank, Rutgers University

    Professor Dietmar J. Manstein

89. 
    Spotlight on… Dietmar Manstein

    Article • FEBS Letters, July 2011, Wiley

    Professor Dietmar J. Manstein

90. 
    Functional characterization of the human myosin-7a motor domain

    Article • Cellular and Molecular Life Sciences, June 2011, Springer Science + Business Media

    Professor Dietmar J. Manstein

91. 
    Mechanism and Specificity of Pentachloropseudilin-mediated Inhibition of Myosin Motor Activity

    Article • Journal of Biological Chemistry, June 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Manuel H Taft, Professor Dietmar J. Manstein

92. 
    Inhibition of Myosin ATPase Activity by Halogenated Pseudilins: A Structure–Activity Study

    Article • Journal of Medicinal Chemistry, May 2011, American Chemical Society (ACS)

    Professor Dietmar J. Manstein

93. 
    CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP- METAVANADATE AND PENTACHLOROCARBAZOLE

    Article • May 2011, Protein Data Bank, Rutgers University

    Professor Dietmar J. Manstein

94. 
    Crystal structure of myosin-2 motor domain in complex with ADP-Metavanadate and blebbistatin

    Article • April 2011, Protein Data Bank, Rutgers University

    Professor Dietmar J. Manstein

95. 
    Comparative Kinetic and Functional Characterization of the Motor Domains of Human Nonmuscle Myosin-2C Isoforms

    Article • Journal of Biological Chemistry, April 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Dietmar J. Manstein

96. 
    Crystal structure of myosin-2 dictyostelium discoideum motor domain S456Y mutant in complex with adp-orthovanadate

    Article • April 2011, Protein Data Bank, Rutgers University

    Professor Dietmar J. Manstein

97. 
    Phalloidin perturbs the interaction of human non-muscle myosin isoforms 2A and 2C1 with F-actin

    Article • FEBS Letters, February 2011, Wiley

    Professor Dietmar J. Manstein, Dr Manuel H Taft

98. 
    Unusual Anchor of a Motor Complex (MyoD–MLC2) to the Plasma Membrane of Toxoplasma gondii

    Article • Traffic, January 2011, Wiley

    Professor Dietmar J. Manstein

99. 
    Article • Extremophiles, January 2011, Springer Science + Business Media

    Professor Dietmar J. Manstein

100. 
     Dictyostelium dynamin B modulates cytoskeletal structures and membranous organelles

     Article • Cellular and Molecular Life Sciences, November 2010, Springer Science + Business Media

     Professor Dietmar J. Manstein

101. 
     Site-directed mutagenesis of the χ subunit of DNA polymerase III and single-stranded DNA-binding protein of E. coli reveals key residues for their interaction

     Article • Nucleic Acids Research, October 2010, Oxford University Press (OUP)

     Professor Dietmar J. Manstein

102. 
     Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization

     Article • Cell, September 2010, Elsevier

     Professor Dietmar J. Manstein

103. 
     Total synthesis of biologically active alkaloids using transition metals

     Article • Pure and Applied Chemistry, August 2010, De Gruyter

     Professor Dietmar J. Manstein

104. 
     Switch-2 Dependent Modulation of the Myosin Power Stroke

     Article • Biophysical Journal, January 2010, Elsevier

     Professor Dietmar J. Manstein

105. 
     Targeted Optimization of a Molecular Motor for Controlling Movement in Biohybrid Devices

     Article • Biophysical Journal, January 2010, Elsevier

     Professor Dietmar J. Manstein

106. 
     Targeted Optimization of a Protein Nanomachine for Operation in Biohybrid Devices

     Article • Angewandte Chemie, December 2009, Wiley

     Professor Dietmar J. Manstein

107. 
     Targeted Optimization of a Protein Nanomachine for Operation in Biohybrid Devices

     Article • Angewandte Chemie, December 2009, Wiley

     Professor Dietmar J. Manstein

108. 
     Total Synthesis of Pentabromo‐ and Pentachloropseudilin, and Synthetic Analogues—Allosteric Inhibitors of Myosin ATPase

     Article • Angewandte Chemie, October 2009, Wiley

     Professor Dietmar J. Manstein

109. 
     Total Synthesis of Pentabromo‐ and Pentachloropseudilin, and Synthetic Analogues—Allosteric Inhibitors of Myosin ATPase

     Article • Angewandte Chemie, October 2009, Wiley

     Professor Dietmar J. Manstein

110. 
     The Ras Pathway Modulator Melophlin A Targets Dynamins

     Article • Angewandte Chemie, September 2009, Wiley

     Professor Dietmar J. Manstein

111. 
     The Ras Pathway Modulator Melophlin A Targets Dynamins

     Article • Angewandte Chemie, September 2009, Wiley

     Professor Dietmar J. Manstein

112. 
     The structural and mechanistic basis of allosteric modulation of myosin motor activity by pharmacological agents

     Article • Acta Crystallographica Section A Foundations of Crystallography, August 2009, International Union of Crystallography

     Professor Dietmar J. Manstein, Dr Manuel H Taft

113. 
     Structure-Function Studies of Myosin Motor Domains

     Article • Biophysical Journal, February 2009, Elsevier

     Professor Dietmar J. Manstein

114. 
     The mechanism of pentabromopseudilin inhibition of myosin motor activity

     Article • Nature Structural & Molecular Biology, January 2009, Springer Science + Business Media

     Professor Dietmar J. Manstein, Dr Manuel H Taft

115. 
     Crystal Structure of the Intact Archaeal Translation Initiation Factor 2 Demonstrates Very High Conformational Flexibility in the α- and β-Subunits

     Article • Journal of Molecular Biology, October 2008, Elsevier

     Professor Dietmar J. Manstein

116. 
     DictyosteliumMyosin-5b Is a Conditional Processive Motor

     Article • Journal of Biological Chemistry, July 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

     Dr Manuel H Taft, Professor Dietmar J. Manstein

117. 
     Mechanism, Regulation, and Functional Properties ofDictyosteliumMyosin-1B

     Article • Journal of Biological Chemistry, December 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Dietmar J. Manstein

118. 
     New Insights into the Interactions of the Translation Initiation Factor 2 from Archaea with Guanine Nucleotides and Initiator tRNA

     Article • Journal of Molecular Biology, October 2007, Elsevier

     Professor Dietmar J. Manstein

119. 
     Enzymatic Activity and Motility of Recombinant Arabidopsis Myosin XI, MYA1

     Article • Plant and Cell Physiology, June 2007, Oxford University Press (OUP)

     Professor Dietmar J. Manstein

120. 
     3D structure of Thermus aquaticus single-stranded DNA-binding protein gives insight into the functioning of SSB proteins

     Article • Nucleic Acids Research, November 2006, Oxford University Press (OUP)

     Professor Dietmar J. Manstein

121. 
     Functional Characterization of the N-terminal Region of Myosin-2

     Article • Journal of Biological Chemistry, September 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Dietmar J. Manstein

122. 
     Dictyostelium myosin-IE is a fast molecular motor involved in phagocytosis

     Article • Journal of Cell Science, February 2006, The Company of Biologists

     Professor Dietmar J. Manstein

123. 
     2P181 The load dependent kinetics of the Chara myosin motor domain(37. Molecular motor (II),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)

     Article • Seibutsu Butsuri, January 2006, Biophysical Society of Japan

     Professor Dietmar J. Manstein

124. 
     Crystal structure of the GTPase domain of rat dynamin 1

     Article • Proceedings of the National Academy of Sciences, September 2005, Proceedings of the National Academy of Sciences

     Professor Dietmar J. Manstein

125. 
     Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the GTPase domain of dynamin 1 from Rattus norvegicus

     Article • August 2005, Protein Data Bank, Rutgers University

     Professor Dietmar J. Manstein

126. 
     Molecular mechanism of actomyosin-based motility

     Article • Cellular and Molecular Life Sciences, May 2005, Springer Science + Business Media

     Professor Dietmar J. Manstein

127. 
     Molecular engineering of myosin

     Article • Philosophical Transactions of the Royal Society B Biological Sciences, December 2004, Royal Society Publishing

     Professor Dietmar J. Manstein

128. 
     Changes in Mg2+Ion Concentration and Heavy Chain Phosphorylation Regulate the Motor Activity of a Class I Myosin

     Article • Journal of Biological Chemistry, December 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Dietmar J. Manstein

129. 
     Conformational changes in actin–myosin isoforms probed by Ni(II)·Gly–Gly–His reactivity

     Article • Journal of Muscle Research and Cell Motility, October 2004, Springer Science + Business Media

     Professor Dietmar J. Manstein

130. 
     Seeing More by Seeing Less: TIRFM Imaging of Cytoskeleton and Membrane Dynamics

     Article • Microscopy and Microanalysis, August 2004, Oxford University Press (OUP)

     Professor Dietmar J. Manstein

131. 
     Molecular engineering of a backwards-moving myosin motor

     Article • Nature, February 2004, Springer Science + Business Media

     Professor Dietmar J. Manstein

132. 
     Recombinant motor domain constructs of Chara corallina myosin display fast motility and high ATPase activity

     Article • Biochemical and Biophysical Research Communications, December 2003, Elsevier

     Professor Dietmar J. Manstein

133. 
     Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum

     Article • September 2003, Protein Data Bank, Rutgers University

     Professor Dietmar J. Manstein

134. 
     A structural model for actin-induced nucleotide release in myosin

     Article • Nature Structural & Molecular Biology, September 2003, Springer Science + Business Media

     Professor Dietmar J. Manstein

135. 
     Nanometer targeting of microtubules to focal adhesions

     Article • Journal of Cell Biology, June 2003, Rockefeller University Press

     Professor Dietmar J. Manstein

136. 
     Interaction of Myosin Subfragment 1 with Forms of Monomeric Actin

     Article • Biochemistry, February 2003, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

137. 
     Analysis of post‐translational modification and characterization of the domain structure of dynamin A from Dictyostelium discoideum

     Article • Journal of Mass Spectrometry, January 2003, Wiley

     Professor Dietmar J. Manstein

138. 
     Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium

     Article • EMBO Reports, December 2002, Wiley

     Professor Dietmar J. Manstein

139. 
     Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium

     Article • EMBO Reports, November 2002, Wiley

     Professor Dietmar J. Manstein

140. 
     MOTOR DOMAIN OF MYOE, A CLASS-I MYOSIN

     Article • June 2002, Protein Data Bank, Rutgers University

     Professor Dietmar J. Manstein

141. 
     Crystal structure of the motor domain of a class-I myosin

     Article • The EMBO Journal, June 2002, Wiley

     Professor Dietmar J. Manstein

142. 
     Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor

     Article • The EMBO Journal, May 2002, Wiley

     Professor Dietmar J. Manstein

143. 
     The dynamin A ring complex: molecular organization and nucleotide-dependent conformational changes

     Article • The EMBO Journal, February 2002, Springer Science + Business Media

     Professor Dietmar J. Manstein

144. 
     PEVK Domain of Titin: An Entropic Spring with Actin-Binding Properties

     Article • Journal of Structural Biology, January 2002, Elsevier

     Professor Dietmar J. Manstein

145. 
     Article • Journal of Muscle Research and Cell Motility, January 2002, Springer Science + Business Media

     Professor Dietmar J. Manstein

146. 
     Crystal structure of a dynamin GTPase domain in both nucleotide-free and GDP-bound forms

     Article • The EMBO Journal, November 2001, Wiley

     Professor Dietmar J. Manstein

147. 
     Lighting up the cell surface with evanescent wave microscopy

     Article • Trends in Cell Biology, July 2001, Elsevier

     Professor Dietmar J. Manstein

148. 
     The Dictyostelium Bcr/Abr-related protein DRG regulates both Rac- and Rab-dependent pathways

     Article • The EMBO Journal, April 2001, Wiley

     Professor Dietmar J. Manstein

149. 
     Single-molecule tracking of myosins with genetically engineered amplifier domains

     Article • Nature Structural Biology, March 2001, Springer Science + Business Media

     Professor Dietmar J. Manstein

150. 
     Structure of a genetically engineered molecular motor

     Article • The EMBO Journal, January 2001, Wiley

     Professor Dietmar J. Manstein

151. 
     Stabilization of the Actomyosin Complex by Negative Charges on Myosin

     Article • Biochemistry, August 2000, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

152. 
     Charge Changes in Loop 2 Affect the Thermal Unfolding of the Myosin Motor Domain Bound to F-Actin

     Article • Biochemistry, March 2000, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

153. 
     Functional Characterization of the Secondary Actin Binding Site of Myosin II

     Article • Biochemistry, October 1999, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

154. 
     Disturbed Communication between Actin- and Nucleotide-binding Sites in a Myosin II with Truncated 50/20-kDa Junction

     Article • Journal of Biological Chemistry, July 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

     Professor Dietmar J. Manstein

155. 
     Kinetic Analysis of Dictyostelium discoideum Myosin Motor Domains with Glycine-to-Alanine Mutations in the Reactive Thiol Region

     Article • Biochemistry, April 1999, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

156. 
     Differences in the ionic interaction of actin with the motor domains of nonmuscle and muscle myosin II

     Article • FEBS Journal, March 1999, Wiley

     Professor Dietmar J. Manstein

157. 
     Role of the salt-bridge between switch-1 and switch-2 of Dictyostelium myosin 1 1Edited by A. R. Fersht

     Article • Journal of Molecular Biology, January 1999, Elsevier

     Professor Dietmar J. Manstein

158. 
     Functional Characterisation of Dictyostelium Myosin II with Conserved Tryptophanyl Residue 501 Mutated to Tyrosine

     Article • Biological Chemistry, January 1999, De Gruyter

     Professor Dietmar J. Manstein

159. 
     Disruption of a Dynamin Homologue Affects Endocytosis, Organelle Morphology, and Cytokinesis in Dictyostelium discoideum

     Article • Molecular Biology of the Cell, January 1999, American Society for Cell Biology (ASCB)

     Professor Dietmar J. Manstein

160. 
     Kinetic Characterization of Myosin Head Fragments with Long-Lived Myosin·ATP States †

     Article • Biochemistry, July 1998, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

161. 
     Modulation of Actin Affinity and Actomyosin Adenosine Triphosphatase by Charge Changes in the Myosin Motor Domain

     Article • Biochemistry, April 1998, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

162. 
     Differential scanning calorimetric study of the thermal unfolding of the motor domain fragments of Dictyostelium discoideum myosin II

     Article • FEBS Journal, January 1998, Wiley

     Professor Dietmar J. Manstein

163. 
     Dictyostelium discoideum Myosin II:  Characterization of Functional Myosin Motor Fragments †

     Article • Biochemistry, January 1997, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

164. 
     Myosin motors with artificial lever arms.

     Article • The EMBO Journal, November 1996, Wiley

     Professor Dietmar J. Manstein

165. 
     Kinetic characterization of the catalytic domain of Dictyostelium discoideum myosin

     Article • Biochemistry, December 1995, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

166. 
     Cloning vectors for the production of proteins in Dictyostelium discoideum

     Article • Gene, August 1995, Elsevier

     Professor Dietmar J. Manstein

167. 
     Overexpression of myosin motor domains in Dictyostelium: screening of transformants and purification of the affinity tagged protein

     Article • Journal of Muscle Research and Cell Motility, June 1995, Springer Science + Business Media

     Professor Dietmar J. Manstein

168. 
     Kinetic characterization of a cytoplasmic myosin motor domain expressed in Dictyostelium discoideum.

     Article • Proceedings of the National Academy of Sciences, September 1993, Proceedings of the National Academy of Sciences

     Professor Dietmar J. Manstein

169. 
     Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1

     Article • Nature, July 1993, Springer Science + Business Media

     Professor Dietmar J. Manstein

170. 
     [27] Molecular genetic tools for study of the cytoskeleton in Dictyostelium

     Article • January 1991, Elsevier

     Professor Dietmar J. Manstein

171. 
     Manipulation and expression of molecular motors in Dictyostelium discoideum

     Article • Journal of Cell Science, January 1991, The Company of Biologists

     Professor Dietmar J. Manstein

172. 
     Complementation of myosin null mutants in Dictyostelium discoideum by direct functional selection

     Article • Developmental Biology, February 1990, Elsevier

     Professor Dietmar J. Manstein

173. 
     Expression and characterization of a functional myosin head fragment in Dictyostelium discoideum

     Article • Science, November 1989, American Association for the Advancement of Science

     Professor Dietmar J. Manstein

174. 
     Hygromycin resistance as a selectable marker in Dictyostelium discoideum.

     Article • Molecular and Cellular Biology, May 1989, ASM Journals

     Professor Dietmar J. Manstein

175. 
     Gene replacement in Dictyostelium: generation of myosin null mutants.

     Article • The EMBO Journal, March 1989, Wiley

     Professor Dietmar J. Manstein

176. 
     Stereochemistry and accessibility of prosthetic groups in flavoproteins

     Article • Biochemistry, April 1988, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

177. 
     Absolute stereochemistry of flavins in enzyme-catalyzed reactions

     Article • Biochemistry, November 1986, American Chemical Society (ACS)

     Professor Dietmar J. Manstein

178. 
     Ultrastructure of native lipoprotein from Escherichia coli envelopes

     Article • Journal of Molecular Biology, June 1986, Elsevier

     Professor Dietmar J. Manstein

179. 
     How Linear Motor Proteins Work

     Article • Springer Science + Business Media

     Professor Dietmar J. Manstein