All Stories

  1. Distinct actin–tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes
  2. Frameshift mutation S368fs in the gene encoding cytoskeletal β-actin leads to ACTB-associated syndromic thrombocytopenia by impairing actin dynamics
  3. Assessment of the Contribution of a Thermodynamic and Mechanical Destabilization of Myosin-Binding Protein C Domain C2 to the Pathomechanism of Hypertrophic Cardiomyopathy-Causing Double Mutation MYBPC3Δ25bp/D389V
  4. Assessment of the Contribution of a Thermodynamic and Mechanical Destabilization of Myosin–Binding Protein C Domain C2 to the Pathomechanism of Hypertrophic Cardiomyopathy–causing Double Mutation MYBPC3Δ25bp/D389V
  5. CORE-MD II: A fast, adaptive, and accurate enhanced sampling method
  6. Improvement of image resolution by combining enhanced confocal microscopy and quantum dot triexciton imaging
  7. Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum
  8. Structural and Biochemical Characterization of a Dye Decolorizing Peroxidase from Dictyostelium discoideum
  9. Allosteric modulation of cardiac myosin mechanics and kinetics by the conjugated omega‐7,9 trans‐fat rumenic acid
  10. Structural and Biochemical Characterization of a Dye Decolorizing Peroxidase from Dictyostelium discoideum
  11. Muscle myosin performance measured with a synthetic nanomachine reveals a class‐specific Ca 2+ ‐sensitivity of the frog myosin II isoform
  12. Mechanochemical properties of human myosin 1C are modulated by isoform-specific differences in the N-terminal extension
  13. Myosin-18B Regulates Higher-Order Organization of the Cardiac Sarcomere through Thin Filament Cross-Linking and Thick Filament Dynamics
  14. Undefeated—Changing the phenamacril scaffold is not enough to beat resistant Fusarium
  15. Small Molecule Effectors of Myosin Function
  16. Unique structure and function of viral rhodopsins
  17. Actin–tropomyosin distribution in non-muscle cells
  18. Phenamacril is a reversible and non-competitive inhibitor of Fusarium class I myosin
  19. Author Correction: Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia
  20. Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia
  21. Treatments targeting inotropy
  22. Co-polymers of Actin and Tropomyosin Account for a Major Fraction of the Human Actin Cytoskeleton
  23. Thrombocytopenia Microcephaly Syndrome - a novel phenotype associated with ACTB mutations
  24. Mechanistic insights into the active site and allosteric communication pathways in human nonmuscle myosin-2C
  25. Three mammalian tropomyosin isoforms have different regulatory effects on nonmuscle myosin-2B and filamentous β-actinin vitro
  26. Pink-beam serial crystallography
  27. N-terminal splicing extensions of the humanMYO1Cgene fine-tune the kinetics of the three full-length myosin IC isoforms
  28. Inward H + pump xenorhodopsin: Mechanism and alternative optogenetic approach
  29. Structural and biochemical studies of sulphotransferase 18 from Arabidopsis thaliana explain its substrate specificity and reaction mechanism
  30. Mechanistic Insights Into The Active Site And Allosteric Communication Pathways In Human Nonmuscle Myosin-2C
  31. Tropomyosin Isoforms Specify Functionally Distinct Actin Filament Populations In Vitro
  32. Myosin Motors: Structural Aspects and Functionality☆
  33. Our muscle at near-atomic resolution - Cryo-EM structure of the F-actin-tropomyosin complex
  34. Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
  35. Datasets from a vapor diffusion mineral precipitation protocol for Dictyostelium stalks
  36. Tropomyosin-Mediated Regulation of Cytoplasmic Myosins
  37. Load-dependent modulation of non-muscle myosin-2A function by tropomyosin 4.2
  38. Structure of the F-Actin-Tropomyosin Complex Revealed by Electron Cryomicroscopy
  39. Arachidonic Acid Directly Binds and Activates Beta-Cardiac Myosin in the Regulated Cardiac Actomyosin Complex
  40. Crystal structure of the dynamin tetramer
  41. The Activation Mechanism of 2′-5′-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity
  42. Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion
  43. Structure of the F-actin–tropomyosin complex
  44. Crystal structure of the rigor-like human non-muscle myosin-2 motor domain
  45. Molecular mechanisms of disease-related human β-actin mutations p.R183W and p.E364K
  46. Silver(I)-Catalyzed Route to Pyrroles: Synthesis of Halogenated Pseudilins as Allosteric Inhibitors for Myosin ATPase and X-ray Crystal Structures of the Protein-Inhibitor Complexes (Eur. J. Org. Chem. 21/2014)
  47. Silver(I)‐Catalyzed Route to Pyrroles: Synthesis of Halogenated Pseudilins as Allosteric Inhibitors for Myosin ATPase and X‐ray Crystal Structures of the Protein–Inhibitor Complexes
  48. Crystal Structure of Human Myosin 1c—The Motor in GLUT4 Exocytosis: Implications for Ca2+ Regulation and 14-3-3 Binding
  49. Small molecule-mediated refolding and activation of myosin motor function
  50. Expression, purification and crystallization of a dye-decolourizing peroxidase from Dictyostelium discoideum
  51. Human Myosin-18B - A Versatile Actin Binding Protein
  52. Structural and Functional Characterization of Nonmuscle Myosin-2B in the Presence of Regulated Actin Filaments
  53. Structural Basis of Myosin 1C Ca2+ Regulation
  54. Functional Characterization of Disease-Related Human β-Actin Mutants
  55. Myosin Structure, Allostery, and Mechano-Chemistry
  56. Kinetic and Thermodynamic Analysis of the Light-induced Processes in Plant and Cyanobacterial Phytochromes
  57. Unconventional Human Myosin-18A
  58. Expression, purification, crystallization and preliminary X-ray crystallographic analysis of human myosin 1c in complex with calmodulin
  59. Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML
  60. Distinct Functional Interactions between Actin Isoforms and Nonsarcomeric Myosins
  61. Functional Dissection of the Dictyostelium discoideum Dynamin B Mitochondrial Targeting Sequence
  62. Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 2)
  63. Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 1)
  64. Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 3)
  65. Structure of bare F-actin filaments obtained from the same sample as the Actin-Tropomyosin-Myosin Complex
  66. Kinetic properties and small‐molecule inhibition of human myosin‐6
  67. Structure of the Rigor Actin-Tropomyosin-Myosin Complex
  68. Functional characterization of the human α-cardiac actin mutations Y166C and M305L involved in hypertrophic cardiomyopathy
  69. Nonmuscle myosin-2: mix and match
  70. EMD57033 Acts as a Pharmacological Chaperone Stabilizing and Activating Myosin Motor Activity
  71. Subnanometer Structure of the Actin/Myosin/Tropomyosin Complex
  72. Functional Characterization of Human Myosin-18A and its Interaction Partners
  73. 4.8 Myosin Motors: Structural Aspects and Functionality
  74. Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V
  75. Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2
  76. Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2
  77. Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2
  78. Spotlight on… Dietmar Manstein
  79. Functional characterization of the human myosin-7a motor domain
  80. Mechanism and Specificity of Pentachloropseudilin-mediated Inhibition of Myosin Motor Activity
  81. Inhibition of Myosin ATPase Activity by Halogenated Pseudilins: A Structure–Activity Study
  82. CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP- METAVANADATE AND PENTACHLOROCARBAZOLE
  83. Crystal structure of myosin-2 motor domain in complex with ADP-Metavanadate and blebbistatin
  84. Comparative Kinetic and Functional Characterization of the Motor Domains of Human Nonmuscle Myosin-2C Isoforms
  85. Crystal structure of myosin-2 dictyostelium discoideum motor domain S456Y mutant in complex with adp-orthovanadate
  86. Phalloidin perturbs the interaction of human non-muscle myosin isoforms 2A and 2C1 with F-actin
  87. Unusual Anchor of a Motor Complex (MyoD–MLC2) to the Plasma Membrane of Toxoplasma gondii
  88. Dictyostelium dynamin B modulates cytoskeletal structures and membranous organelles
  89. Site-directed mutagenesis of the χ subunit of DNA polymerase III and single-stranded DNA-binding protein of E. coli reveals key residues for their interaction
  90. Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization
  91. Total synthesis of biologically active alkaloids using transition metals
  92. Switch-2 Dependent Modulation of the Myosin Power Stroke
  93. Targeted Optimization of a Molecular Motor for Controlling Movement in Biohybrid Devices
  94. Targeted Optimization of a Protein Nanomachine for Operation in Biohybrid Devices
  95. Targeted Optimization of a Protein Nanomachine for Operation in Biohybrid Devices
  96. Total Synthesis of Pentabromo‐ and Pentachloropseudilin, and Synthetic Analogues—Allosteric Inhibitors of Myosin ATPase
  97. Total Synthesis of Pentabromo‐ and Pentachloropseudilin, and Synthetic Analogues—Allosteric Inhibitors of Myosin ATPase
  98. The Ras Pathway Modulator Melophlin A Targets Dynamins
  99. The Ras Pathway Modulator Melophlin A Targets Dynamins
  100. The structural and mechanistic basis of allosteric modulation of myosin motor activity by pharmacological agents
  101. Structure-Function Studies of Myosin Motor Domains
  102. The mechanism of pentabromopseudilin inhibition of myosin motor activity
  103. Crystal Structure of the Intact Archaeal Translation Initiation Factor 2 Demonstrates Very High Conformational Flexibility in the α- and β-Subunits
  104. DictyosteliumMyosin-5b Is a Conditional Processive Motor
  105. Mechanism, Regulation, and Functional Properties ofDictyosteliumMyosin-1B
  106. New Insights into the Interactions of the Translation Initiation Factor 2 from Archaea with Guanine Nucleotides and Initiator tRNA
  107. Enzymatic Activity and Motility of Recombinant Arabidopsis Myosin XI, MYA1
  108. 3D structure of Thermus aquaticus single-stranded DNA-binding protein gives insight into the functioning of SSB proteins
  109. Functional Characterization of the N-terminal Region of Myosin-2
  110. Dictyostelium myosin-IE is a fast molecular motor involved in phagocytosis
  111. 2P181 The load dependent kinetics of the Chara myosin motor domain(37. Molecular motor (II),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
  112. Crystal structure of the GTPase domain of rat dynamin 1
  113. Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the GTPase domain of dynamin 1 from Rattus norvegicus
  114. Molecular mechanism of actomyosin-based motility
  115. Molecular engineering of myosin
  116. Changes in Mg2+Ion Concentration and Heavy Chain Phosphorylation Regulate the Motor Activity of a Class I Myosin
  117. Conformational changes in actin–myosin isoforms probed by Ni(II)·Gly–Gly–His reactivity
  118. Seeing More by Seeing Less: TIRFM Imaging of Cytoskeleton and Membrane Dynamics
  119. Molecular engineering of a backwards-moving myosin motor
  120. Recombinant motor domain constructs of Chara corallina myosin display fast motility and high ATPase activity
  121. Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum
  122. A structural model for actin-induced nucleotide release in myosin
  123. Nanometer targeting of microtubules to focal adhesions
  124. Interaction of Myosin Subfragment 1 with Forms of Monomeric Actin
  125. Analysis of post‐translational modification and characterization of the domain structure of dynamin A from Dictyostelium discoideum
  126. Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium
  127. Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium
  128. MOTOR DOMAIN OF MYOE, A CLASS-I MYOSIN
  129. Crystal structure of the motor domain of a class-I myosin
  130. Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor
  131. The dynamin A ring complex: molecular organization and nucleotide-dependent conformational changes
  132. PEVK Domain of Titin: An Entropic Spring with Actin-Binding Properties
  133. Crystal structure of a dynamin GTPase domain in both nucleotide-free and GDP-bound forms
  134. Lighting up the cell surface with evanescent wave microscopy
  135. The Dictyostelium Bcr/Abr-related protein DRG regulates both Rac- and Rab-dependent pathways
  136. Single-molecule tracking of myosins with genetically engineered amplifier domains
  137. Structure of a genetically engineered molecular motor
  138. Stabilization of the Actomyosin Complex by Negative Charges on Myosin
  139. Charge Changes in Loop 2 Affect the Thermal Unfolding of the Myosin Motor Domain Bound to F-Actin
  140. Functional Characterization of the Secondary Actin Binding Site of Myosin II
  141. Disturbed Communication between Actin- and Nucleotide-binding Sites in a Myosin II with Truncated 50/20-kDa Junction
  142. Kinetic Analysis of Dictyostelium discoideum Myosin Motor Domains with Glycine-to-Alanine Mutations in the Reactive Thiol Region
  143. Differences in the ionic interaction of actin with the motor domains of nonmuscle and muscle myosin II
  144. Role of the salt-bridge between switch-1 and switch-2 of Dictyostelium myosin 1 1Edited by A. R. Fersht
  145. Functional Characterisation of Dictyostelium Myosin II with Conserved Tryptophanyl Residue 501 Mutated to Tyrosine
  146. Disruption of a Dynamin Homologue Affects Endocytosis, Organelle Morphology, and Cytokinesis in Dictyostelium discoideum
  147. Kinetic Characterization of Myosin Head Fragments with Long-Lived Myosin·ATP States †
  148. Modulation of Actin Affinity and Actomyosin Adenosine Triphosphatase by Charge Changes in the Myosin Motor Domain
  149. Differential scanning calorimetric study of the thermal unfolding of the motor domain fragments of Dictyostelium discoideum myosin II
  150. Dictyostelium discoideum Myosin II:  Characterization of Functional Myosin Motor Fragments †
  151. Myosin motors with artificial lever arms.
  152. Kinetic characterization of the catalytic domain of Dictyostelium discoideum myosin
  153. Cloning vectors for the production of proteins in Dictyostelium discoideum
  154. Overexpression of myosin motor domains in Dictyostelium: screening of transformants and purification of the affinity tagged protein
  155. Kinetic characterization of a cytoplasmic myosin motor domain expressed in Dictyostelium discoideum.
  156. Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1
  157. [27] Molecular genetic tools for study of the cytoskeleton in Dictyostelium
  158. Manipulation and expression of molecular motors in Dictyostelium discoideum
  159. Complementation of myosin null mutants in Dictyostelium discoideum by direct functional selection
  160. Expression and characterization of a functional myosin head fragment in Dictyostelium discoideum
  161. Hygromycin resistance as a selectable marker in Dictyostelium discoideum.
  162. Gene replacement in Dictyostelium: generation of myosin null mutants.
  163. Stereochemistry and accessibility of prosthetic groups in flavoproteins
  164. Absolute stereochemistry of flavins in enzyme-catalyzed reactions
  165. Ultrastructure of native lipoprotein from Escherichia coli envelopes
  166. How Linear Motor Proteins Work