All Stories

  1. A structure-based design approach to advance the allyltyrosine-based series of HIV integrase inhibitors

    Article • Tetrahedron, March 2018, Elsevier

    Christopher Gordon

  2. Chemoselective Flow Hydrogenation Approaches to Diversify the Cytotoxic Tetrahydroepoxyisoindole Carboxamide Scaffold

    Article • Advanced Synthesis & Catalysis, February 2018, Wiley

    Christopher Gordon

  3. The renascence of continuous-flow peptide synthesis – an abridged account of solid and solution-based approaches

    Article • Organic & Biomolecular Chemistry, January 2018, Royal Society of Chemistry

    Christopher Gordon

  4. Small-Molecule Inhibitors of the NusB–NusE Protein–Protein Interaction with Antibiotic Activity

    Article • ACS Omega, July 2017, American Chemical Society (ACS)

    Christopher Gordon

  5. Cytotoxicity of a Series of Norcantharidin-Inspired Tetrahydroepoxyisoindole Carboxamides

    Article • ChemMedChem, January 2017, Wiley

    Christopher Gordon

  6. Efficient phosphine-mediated formal C(sp3)–C(sp3) coupling reactions of alkyl halides in batch and flow

    Article • Chemical Communications, January 2017, Royal Society of Chemistry

    Christopher Gordon

  7. Identification and validation of small molecule modulators of the NusB-NusE interaction

    Article • Bioorganic & Medicinal Chemistry Letters, January 2017, Elsevier

    Christopher Gordon

  8. Small molecule Hedgehog pathway antagonists

    Article • Organic & Biomolecular Chemistry, January 2017, Royal Society of Chemistry

    Christopher Gordon

  9. Transition Metal Intercalators as Anticancer Agents—Recent Advances

    Article • International Journal of Molecular Sciences, October 2016, MDPI AG

    Christopher Gordon

  10. Truncated Autoinducing Peptides as Antagonists of Staphylococcus lugdunensis Quorum Sensing

    Article • Journal of Medicinal Chemistry, September 2016, American Chemical Society (ACS)

    Christopher Gordon

  11. Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors

    Article • Organic & Biomolecular Chemistry, January 2016, Royal Society of Chemistry

    Prof Eileen A McLaughlin, Christopher Gordon

  12. The discovery of allyltyrosine based tripeptides as selective inhibitors of the HIV-1 integrase strand-transfer reaction

    Article • Organic & Biomolecular Chemistry, January 2016, Royal Society of Chemistry

    Christopher Gordon

  13. Heck Coupling in Ionic Liquids

    Article • May 2015, IntechOpen

    Christopher Gordon

  14. Defining the Mechanisms by Which the Reactive Oxygen Species By-Product, 4-Hydroxynonenal, Affects Human Sperm Cell Function1

    Article • Biology of Reproduction, April 2015, Oxford University Press (OUP)

    Christopher Gordon

  15. The expanding utility of continuous flow hydrogenation

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Dr Christopher P Gordon, Christopher Gordon

  16. Discovery of acrylonitrile-based small molecules active against Haemonchus contortus

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Adam McCluskey, Dr Christopher P Gordon, Christopher Gordon

  17. Hedgehog signalling pathway inhibitors as cancer suppressing agents

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Adam McCluskey, Dr Christopher P Gordon, Prof Eileen A McLaughlin, Christopher Gordon

  18. Chemoselective flow hydrogenation approaches to isoindole-7-carboxylic acids and 7-oxa-bicyclio[2.2.1]heptanes

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Adam McCluskey, Christopher Gordon

  19. The influence of ionic liquids on the Knoevenagel condensation of 1H-pyrrole-2-carbaldehyde with phenyl acetonitriles – cytotoxic 3-substituted-(1H-pyrrol-2-yl)acrylonitriles

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Adam McCluskey, Dr Christopher P Gordon, Christopher Gordon

  20. An efficient continuous flow approach to furnish furan-based biaryls

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Adam McCluskey, Dr Christopher P Gordon, Christopher Gordon

  21. Attenuating Staphylococcus aureus Virulence Gene Regulation: A Medicinal Chemistry Perspective

    Article • Journal of Medicinal Chemistry, January 2013, American Chemical Society (ACS)

    Christopher Gordon, Professor Paul Williams

  22. Norcantharimide analogues possessing terminal phosphate esters and their anti-cancer activity

    Article • Bioorganic & Medicinal Chemistry, September 2011, Elsevier

    Dr Christopher P Gordon, Christopher Gordon

  23. Inhibition of Dynamin by Dynole 34-2 Induces Cell Death following Cytokinesis Failure in Cancer Cells

    Article • Molecular Cancer Therapeutics, July 2011, American Association for Cancer Research (AACR)

    Andrew Morokoff, Christopher Gordon

  24. A Flow Chemistry Approach to Norcantharidin Analogues

    Article • Letters in Drug Design & Discovery, July 2011, Bentham Science Publishers

    Dr Christopher P Gordon, Christopher Gordon

  25. Investigation of the one-pot synthesis of quinolin-2-(1H)-ones and the discovery of a variation of the three-component Ugi reaction

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    Dr Christopher P Gordon, Christopher Gordon

  26. Anti-malarial, anti-algal, anti-tubercular, anti-bacterial, anti-photosynthetic, and anti-fouling activity of diterpene and diterpene isonitriles from the tropical marine sponge Cymbastela hooperi

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    Dr Christopher P Gordon, Christopher Gordon

  27. An Ugi-intramolecular Diels–Alder route to highly substituted tetrahydroepoxyisoindole carboxamides

    Article • Tetrahedron, January 2011, Elsevier

    Dr Christopher P Gordon, Christopher Gordon

  28. The antiplasmodial activity of norcantharidin analogs

    Article • Bioorganic & Medicinal Chemistry Letters, November 2010, Elsevier

    Dr Christopher P Gordon, Christopher Gordon

  29. The Pthaladyns: GTP Competitive Inhibitors of Dynamin I and II GTPase Derived from Virtual Screening

    Article • Journal of Medicinal Chemistry, June 2010, American Chemical Society (ACS)

    Dr Christopher P Gordon, Christopher Gordon

  30. The Dynamin Inhibitors MiTMAB and OcTMAB Induce Cytokinesis Failure and Inhibit Cell Proliferation in Human Cancer Cells

    Article • Molecular Cancer Therapeutics, June 2010, American Association for Cancer Research (AACR)

    Christopher Gordon

  31. Iminochromene Inhibitors of Dynamins I and II GTPase Activity and Endocytosis

    Article • Journal of Medicinal Chemistry, May 2010, American Chemical Society (ACS)

    Dr Christopher P Gordon, Christopher Gordon

  32. Calcineurin activity is required for the completion of cytokinesis

    Article • Cellular and Molecular Life Sciences, May 2010, Springer Science + Business Media

    Christopher Gordon

  33. A facile, protic ionic liquid route to N-substituted 5-hydroxy-4-methyl-3-oxoisoindoline-1-carboxamides and N-substituted 3-oxoisoindoline-4-carboxylic acids

    Article • Green Chemistry, January 2010, Royal Society of Chemistry

    Dr Christopher P Gordon, Christopher Gordon

  34. Inhibition of Dynamin Mediated Endocytosis by the Dynoles—Synthesis and Functional Activity of a Family of Indoles

    Article • Journal of Medicinal Chemistry, May 2009, American Chemical Society (ACS)

    Dr Christopher P Gordon, Christopher Gordon

  35. Norcantharidin Analogues: Synthesis, Anticancer Activity and Protein Phosphatase 1 and 2A Inhibition

    Article • ChemMedChem, December 2008, Wiley

    Dr Christopher P Gordon, Christopher Gordon

  36. Aryl Nitro Reduction with Iron Powder or Stannous Chloride under Ultrasonic Irradiation

    Article • Synthetic Communications, August 2007, Taylor & Francis

    Paul Keller, Christopher Gordon

  37. Control of HIV Through the Inhibition of HIV-1 Integrase: A Medicinal Chemistry Perspective

    Article • Medicinal Chemistry, March 2007, Bentham Science Publishers

    Paul Keller, Christopher Gordon

  38. Control of Hepatitis C:  A Medicinal Chemistry Perspective

    Article • Journal of Medicinal Chemistry, January 2005, American Chemical Society (ACS)

    Christopher Gordon