All Stories

  1. Alkaloids from the root of Indonesian Annona muricata L

    Article • Natural Product Research, July 2019, Taylor & Francis

    Paul Keller

  2. Phytochemical and Pharmacological Studies on Four Indonesian Epiphytic Medicinal Plants: Drynaria rigidula, Hydnophytum formicarum, Usnea misaminensis, and Calymperes schmidtii

    Article • Natural Product Communications, June 2019, SAGE Publications

    Paul Keller

  3. Binaphthyl-1,2,3-triazole peptidomimetics with activity against Clostridium difficile and other pathogenic bacteria

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Paul Keller

  4. A twist of nature – the significance of atropisomers in biological systems

    Article • Natural Product Reports, January 2015, Royal Society of Chemistry

    Paul Keller

  5. Synthesis and antimicrobial activity of binaphthyl-based, functionalized oxazole and thiazole peptidomimetics

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Paul Keller

  6. Erratum to “A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain” [J. Ethnopharmacol. 150 (3) (2013) 953–959]

    Article • Journal of Ethnopharmacology, May 2014, Elsevier

    Paul Keller

  7. Discovery of in silico hits targeting the nsP3 macro domain of chikungunya virus

    Article • Journal of Molecular Modeling, April 2014, Springer Science + Business Media

    Paul Keller

  8. Facile Synthesis and Preliminary Structure–Activity Analysis of New Sulfonamides Against Trypanosoma brucei

    Article • ACS Medicinal Chemistry Letters, March 2014, American Chemical Society (ACS)

    Paul Keller

  9. Synthesis and in vitro evaluation of tetrahydroisoquinolines with pendent aromatics as sigma-2 (σ2) selective ligands

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Paul Keller

  10. [60]Fullerenyl amino acids and peptides: a review of their synthesis and applications

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Paul Keller

  11. A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain

    Article • Journal of Ethnopharmacology, December 2013, Elsevier

    Paul Keller

  12. Chikungunya Virus: Emerging Targets and New Opportunities for Medicinal Chemistry

    Article • Journal of Medicinal Chemistry, October 2013, American Chemical Society (ACS)

    Paul Keller

  13. Rapid Cascade Synthesis of Poly-Heterocyclic Architectures from Indigo

    Article • The Journal of Organic Chemistry, July 2013, American Chemical Society (ACS)

    Paul Keller

  14. Structure based design towards the identification of novel binding sites and inhibitors for the chikungunya virus envelope proteins

    Article • Journal of Molecular Graphics and Modelling, July 2013, Elsevier

    Paul Keller

  15. Inhibition of TNF-α production in LPS-activated THP-1 monocytic cells by the crude extracts of seven Bhutanese medicinal plants

    Article • Journal of Ethnopharmacology, July 2013, Elsevier

    Paul Keller

  16. An assessment of the Bhutanese traditional medicine for its ethnopharmacology, ethnobotany and ethnoquality: Textual understanding and the current practices

    Article • Journal of Ethnopharmacology, June 2013, Elsevier

    Paul Keller

  17. Dengue virus therapeutic intervention strategies based on viral, vector and host factors involved in disease pathogenesis

    Article • Pharmacology & Therapeutics, February 2013, Elsevier

    Paul Keller

  18. Binaphthyl-anchored antibacterial tripeptide derivatives with hydrophobic C-terminal amino acid variations

    Article • Beilstein Journal of Organic Chemistry, August 2012, Beilstein Institut

    Paul Keller

  19. Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia

    Article • Journal of Ethnopharmacology, August 2012, Elsevier

    Paul Keller

  20. Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of Phytochemicals and biological activities

    Article • Journal of Ethnopharmacology, September 2011, Elsevier

    Paul Keller

  21. Synthesis and antibacterial activity of C2-symmetric binaphthyl scaffolded amino acid derivatives

    Article • European Journal of Medicinal Chemistry, September 2011, Elsevier

    Paul Keller

  22. Synthesis and antibacterial activity of some binaphthyl-supported macrocycles containing a cationic amino acid

    Article • Bioorganic & Medicinal Chemistry, June 2011, Elsevier

    Paul Keller

  23. Ethnobotanical authentication and identification of Khrog-sman (Lower Elevation Medicinal Plants) of Bhutan

    Article • Journal of Ethnopharmacology, April 2011, Elsevier

    Paul Keller

  24. ChemInform Abstract: The First Syntheses of Enantiopure 2,2′‐Biindoline.

    Article • ChemInform, March 2011, Wiley

    Paul Keller

  25. Investigation into the Extension of the Non-Nucleoside Reverse Transcriptase Binding Pocket

    Article • Australian Journal of Chemistry, January 2011, CSIRO Publishing

    Paul Keller

  26. ChemInform Abstract: Synthesis of Reaction‐Ready 6,6′‐Biindole and 6,6′‐Biisatin via Palladium(II)‐Catalyzed Intramolecular C—H Functionalization.

    Article • ChemInform, October 2010, Wiley

    Paul Keller

  27. The attempted stereoselective synthesis of chiral 2,2′-biindoline

    Article • Tetrahedron, August 2010, Elsevier

    Paul Keller

  28. Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 2

    Article • Bioorganic & Medicinal Chemistry, July 2010, Elsevier

    Paul Keller

  29. Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 1

    Article • Bioorganic & Medicinal Chemistry, April 2010, Elsevier

    Paul Keller

  30. Synthesis of reaction-ready 6,6′-biindole and 6,6′-biisatin via palladium(ii)-catalysed intramolecular C–H functionalisation

    Article • Chemical Communications, January 2010, Royal Society of Chemistry

    Paul Keller

  31. The first syntheses of enantiopure 2,2′-biindoline

    Article • Chemical Communications, January 2010, Royal Society of Chemistry

    Paul Keller

  32. Novel spiro and fused heterocycles from the allylation of indigo

    Article • Tetrahedron Letters, December 2009, Elsevier

    Paul Keller

  33. The Medicinal Chemistry of Dengue Fever

    Article • Journal of Medicinal Chemistry, September 2009, American Chemical Society (ACS)

    Paul Keller

  34. ChemInform Abstract: Reactions of Electron‐Rich Indoles with Triflic Anhydride.

    Article • ChemInform, August 2009, Wiley

    Paul Keller

  35. Binaphthyl scaffolded peptoids via ring-closing metathesis reactions and their anti-bacterial activities

    Article • Bioorganic & Medicinal Chemistry Letters, June 2009, Elsevier

    Paul Keller

  36. Reactions of electron-rich indoles with triflic anhydride

    Article • Tetrahedron Letters, May 2009, Elsevier

    Paul Keller

  37. ChemInform Abstract: Effective Synthetic Routes to Activated Pyrrolo[3,2,1‐hi]indoles.

    Article • ChemInform, April 2009, Wiley

    Paul Keller

  38. New cyclic peptides via ring-closing metathesis reactions and their anti-bacterial activities

    Article • Tetrahedron, December 2008, Elsevier

    Paul Keller

  39. Effective synthetic routes to activated pyrrolo[3,2,1-hi]indoles

    Article • Tetrahedron, December 2008, Elsevier

    Paul Keller

  40. ChemInform Abstract: Oxidative Coupling of Indoles Using Thallium(III) Trifluoroacetate.

    Article • ChemInform, November 2008, Wiley

    Paul Keller

  41. Oxidative coupling of indoles using thallium(III) trifluoroacetate

    Article • Tetrahedron, August 2008, Elsevier

    Paul Keller

  42. Antimalarial Activity of 2,4-Diaminopyrimidines

    Article • Letters in Drug Design & Discovery, June 2008, Bentham Science Publishers

    Paul Keller

  43. ChemInform Abstract: Aryl Nitro Reduction with Iron Powder or Stannous Chlorides under Ultrasonic Irradiation.

    Article • ChemInform, January 2008, Wiley

    Paul Keller

  44. Aryl Nitro Reduction with Iron Powder or Stannous Chloride under Ultrasonic Irradiation

    Article • Synthetic Communications, August 2007, Taylor & Francis

    Paul Keller, Christopher Gordon

  45. A new methodology for the simulation of flexible protein–ligand interactions

    Article • Journal of Molecular Graphics and Modelling, July 2007, Elsevier

    Paul Keller

  46. Control of HIV Through the Inhibition of HIV-1 Integrase: A Medicinal Chemistry Perspective

    Article • Medicinal Chemistry, March 2007, Bentham Science Publishers

    Paul Keller, Christopher Gordon

  47. Corticotropin Releasing Hormone - A GPCR Drug Target

    Article • Current Drug Targets, January 2007, Bentham Science Publishers

    Paul Keller

  48. Reactions of Iminoglycines with C60 Fullerene and Their Unambiguous Characterization Using NMR Spectroscopy

    Article • ChemInform, December 2006, Wiley

    Paul Keller

  49. Reactions of iminoglycines with C60 fullerene and their unambiguous characterisation using NMR spectroscopy

    Article • Comptes Rendus Chimie, July 2006, Cellule MathDoc/CEDRAM

    Paul Keller

  50. The Synthesis and Testing of Arenearylpyrimidylmethanes as Antimalarial Agents

    Article • ChemMedChem, June 2006, Wiley

    Paul Keller

  51. Structural Reassignment of the Mono‐ and Bis‐Addition Products from the Addition Reactions of N‐(Diphenylmethylene)glycinate Esters to [60]Fullerene under Bingel Conditions.

    Article • ChemInform, December 2005, Wiley

    Paul Keller

  52. Atroposelective Synthesis of Axially Chiral Biaryl Compounds

    Article • ChemInform, October 2005, Wiley

    Paul Keller

  53. A Convenient and Efficient Synthesis of (S)‐Lysine and (S)‐Arginine Homologues via Olefin Cross‐Metathesis.

    Article • ChemInform, October 2005, Wiley

    Paul Keller

  54. Structural Reassignment of the Mono- and Bis-Addition Products from the Addition Reactions of N-(Diphenylmethylene)glycinate Esters to [60]Fullerene under Bingel Conditions

    Article • The Journal of Organic Chemistry, September 2005, American Chemical Society (ACS)

    Paul Keller

  55. Atroposelective Synthesis of Axially Chiral Biaryl Compounds

    Article • Angewandte Chemie, August 2005, Wiley

    Paul Keller

  56. A convenient and efficient synthesis of (S)-lysine and (S)-arginine homologues via olefin cross-metathesis

    Article • Tetrahedron, July 2005, Elsevier

    Paul Keller

  57. Combining structure-based drug design and pharmacophores

    Article • Journal of Molecular Graphics and Modelling, April 2005, Elsevier

    Paul Keller

  58. By Formation of the Biaryl Bond

    Article • January 2005, Thieme Publishing Group

    Paul Keller

  59. By Formation of the Biaryl Bond

    Article • January 2005, Thieme Publishing Group

    Paul Keller

  60. Synthesis of Carbazole‐Linked Cyclic and Acyclic Peptoids with Antibacterial Activity.

    Article • ChemInform, January 2004, Wiley

    Paul Keller

  61. Synthesis of carbazole-linked cyclic and acyclic peptoids with antibacterial activity

    Article • Tetrahedron, October 2003, Elsevier

    Paul Keller

  62. Anilinopyrimidines as Novel Antituberculosis Agents.

    Article • ChemInform, August 2003, Wiley

    Paul Keller

  63. Anilinopyrimidines as novel antituberculosis agents

    Article • Bioorganic & Medicinal Chemistry Letters, May 2003, Elsevier

    Paul Keller

  64. The Synthesis of a Novel Binaphthyl‐Based Cyclic Peptoid with anti‐Bacterial Activity.

    Article • ChemInform, March 2003, Wiley

    Paul Keller

  65. Novel pharmacophore-based methods reveal gossypol as a reverse transcriptase inhibitor

    Article • Journal of Molecular Graphics and Modelling, March 2003, Elsevier

    Paul Keller

  66. Synthesis, molecular modeling and biological activity of methyl and thiomethyl substituted pyrimidines as corticotropin releasing hormone type 1 antagonists

    Article • Organic & Biomolecular Chemistry, January 2003, Royal Society of Chemistry

    Paul Keller

  67. Mining the Chemical Abstracts database with pharmacophore-based queries

    Article • Journal of Molecular Graphics and Modelling, December 2002, Elsevier

    Paul Keller

  68. The synthesis of a novel binaphthyl-based cyclic peptoid with anti-bacterial activityElectronic supplementary information (ESI) available: ESMS data. See http://www.rsc.org/suppdata/nj/b2/b205894b/

    Article • New Journal of Chemistry, October 2002, Royal Society of Chemistry

    Paul Keller

  69. ChemInform Abstract: The Synthesis of a Novel Carbazole‐Linked Cyclic Peptoid with Antibacterial Activity.

    Article • ChemInform, June 2002, Wiley

    Paul Keller

  70. The Synthesis of a Novel Carbazole-linked Cyclic Peptoid with Antibacterial Activity

    Article • Synlett, January 2002, Thieme Publishing Group

    Paul Keller

  71. Unequivocal assignment of the fullerene carbons of diethyl 1,2‐methano[60]fullerene 61,61‐dicarboxylate using 2D INADEQUATE NMR spectroscopy

    Article • Magnetic Resonance in Chemistry, June 2001, Wiley

    Paul Keller

  72. Development of computational and graphical tools for analysis of movement and flexibility in large molecules

    Article • Journal of Molecular Graphics and Modelling, June 2000, Elsevier

    Paul Keller

  73. Corticotropin releasing hormone: therapeutic implications and medicinal chemistry developments

    Article • Bioorganic & Medicinal Chemistry, June 2000, Elsevier

    Paul Keller

  74. ChemInform Abstract: [60]Fullerene Amino Acids and Related Derivatives

    Article • ChemInform, April 2000, Wiley

    Paul Keller

  75. Unexpected regiochemistry of a tethered bismethano[60]fullerene

    Article • Chemical Communications, January 2000, Royal Society of Chemistry

    Paul Keller

  76. [60]Fullerene Amino Acids and Related Derivatives

    Article • Fullerene Science and Technology, November 1999, Taylor & Francis

    Paul Keller

  77. Pharmacophore Development for Corticotropin-Releasing Hormone:  New Insights into Inhibitor Activity

    Article • Journal of Medicinal Chemistry, June 1999, American Chemical Society (ACS)

    Paul Keller

  78. Docking experiments in the flexible non-nucleoside inhibitor binding pocket of HIV-1 reverse transcriptase

    Article • Bioorganic & Medicinal Chemistry, June 1999, Elsevier

    Paul Keller

  79. ChemInform Abstract: Synthesis of a 1,2‐Dihydro[60]fullerylglycine Derivative by a Novel Cyclopropane Ring Opening of a Methano[60]fullerene.

    Article • ChemInform, March 1999, Wiley

    Paul Keller

  80. A Convergent Total Synthesis of the Michellamines

    Article • The Journal of Organic Chemistry, January 1998, American Chemical Society (ACS)

    Paul Keller

  81. Synthesis of a 1,2-dihydro[60]fullerylglycine derivative by a novel cyclopropane ring opening of a methano[60]fullerene

    Article • Chemical Communications, January 1998, Royal Society of Chemistry

    Paul Keller

  82. ChemInform Abstract: Acetogenic Isoquinoline Alkaloids. Part 70. Convergent Total Synthesis of the Michellamines

    Article • ChemInform, March 1995, Wiley

    Paul Keller

  83. ChemInform Abstract: Novel Concepts in Directed Biaryl Synthesis. Part 42. A New Approach to Atroposelective Biaryl Synthesis, Utilizing Chiral Carbon‐Carbon Bridges.

    Article • ChemInform, January 1995, Wiley

    Paul Keller

  84. ChemInform Abstract: Acetogenic Isoquinoline Alkaloids. Part 69. “Biomimetic” Oxidative Dimerization of Korupensamine A: Completion of the First Total Synthesis of Michellamines A, B, and C.

    Article • ChemInform, January 1995, Wiley

    Paul Keller

  85. Convergent total synthesis of the michellamines

    Article • Tetrahedron Letters, October 1994, Elsevier

    Paul Keller

  86. A New Approach to Atroposelective Biaryl Synthesis, Utilizing Chiral Carbon-Carbon Bridges 1

    Article • Synlett, January 1994, Thieme Publishing Group

    Paul Keller

  87. Substitution, oxidation and addition reactions at C-7 of activated indoles

    Article • Tetrahedron, January 1994, Elsevier

    Paul Keller

  88. ‘Biomimetic’ oxidative dimerization of korupensamine A: Completion of the first total synthesis of michellamines A, B, and C

    Article • Tetrahedron, January 1994, Elsevier

    Paul Keller

  89. ChemInform Abstract: Palladium‐Catalyzed Intramolecular Cyclization of 7‐Halo‐N‐allyl‐ indoles.

    Article • ChemInform, December 1992, Wiley

    Paul Keller

  90. Palladium-catalysed intramolecular cyclisation of 7-halo-N-allyl-indoles

    Article • Tetrahedron, September 1992, Elsevier

    Paul Keller