All Stories

  1. Bioinformatics characterization of BcsA-like orphan proteins suggest they form a novel family of pseudomonad cyclic-β-glucan synthases

    Article • PLoS ONE, June 2023, PLOS

    Dr Andrew J Spiers

  2. Investigating quorum-quenching marine bacilli as potential biocontrol agents for protection of shrimps against Early Mortality Syndrome (EMS)

    Article • Scientific Reports, March 2023, Springer Science + Business Media

    Dr Andrew J Spiers

  3. eDNA, Amyloid Fibers and Membrane Vesicles Identified in Pseudomonas fluorescens SBW25 Biofilms

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Dr Andrew J Spiers

  4. Azithromycin possesses biofilm–inhibitory activity and potentiates non-bactericidal colistin methanesulfonate (CMS) and polymyxin B against Klebsiella pneumonia

    Article • PLoS ONE, July 2022, PLOS

    Dr Andrew J Spiers

  5. eDNA Inactivation and Biofilm Inhibition by the PolymericBiocide Polyhexamethylene Guanidine Hydrochloride (PHMG-Cl)

    Article • International Journal of Molecular Sciences, January 2022, MDPI AG

    Dr Andrew J Spiers

  6. Community biofilm-formation, stratification and productivity in serially-transferred microcosms

    Article • FEMS Microbiology Letters, November 2020, Oxford University Press (OUP)

    Dr Andrew J Spiers

  7. Extending an Eco-Evolutionary Understanding of Biofilm-Formation at the Air-Liquid Interface to Community Biofilms

    Article • October 2020, IntechOpen

    Dr Andrew J Spiers

  8. Three biofilm types produced by a model pseudomonad are differentiated by structural characteristics and fitness advantage

    Article • Microbiology, August 2020, Society for General Microbiology

    Dr Andrew J Spiers

  9. Biofilm and productivity-associated community changes in serial-transfer experiments in heterogeneous liquid microcosms

    Article • July 2020, Copernicus GmbH

    Dr Andrew J Spiers

  10. Chemical stress contribution in bacterial biofilm formation

    Article • July 2020, Copernicus GmbH

    Dr Andrew J Spiers

  11. Characterisation of surfactant-expressing bacteria and their potential bioremediation properties from hydrocarbon-contaminated and uncontaminated soils

    Article • Access Microbiology, July 2020, Society for General Microbiology

    Dr Andrew J Spiers

  12. Penetrating the air–liquid interface is the key to colonization and wrinkly spreader fitness

    Article • Microbiology, October 2019, Society for General Microbiology

    Dr Andrew J Spiers

  13. Penetration of the air–liquid interface is key to the Wrinkly Spreader success

    Article • Access Microbiology, March 2019, Society for General Microbiology

    Dr Andrew J Spiers

  14. Priming winter wheat seeds with the bacterial quorum sensing signal N-hexanoyl-L-homoserine lactone (C6-HSL) shows potential to improve plant growth and seed yield

    Article • PLoS ONE, February 2019, PLOS

    Dr Andrew J Spiers

  15. Differential expression of insecticide resistance genes in Anopheles gambiae from Northern Nigeria

    Article • Journal of Biotechnology, August 2018, Elsevier

    Dr Andrew J Spiers

  16. Control of Pore Geometry in Soil Microcosms and Its Effect on the Growth and Spread of Pseudomonas and Bacillus sp.

    Article • Frontiers in Environmental Science, July 2018, Frontiers

    Dr Andrew J Spiers

  17. Examining c-di-GMP and possible quorum sensing regulation in Pseudomonas fluorescens SBW25: links between intra- and inter-cellular regulation benefits community cooperative activities such as biofilm formation

    Article • The Ukrainian Biochemical Journal, June 2018, Co. Ltd. Ukrinformnauka

    Dr Andrew J Spiers

  18. Uncovering behavioural diversity amongst high-strength Pseudomonas spp. surfactants at the limit of liquid surface tension reduction

    Article • FEMS Microbiology Letters, January 2018, Oxford University Press (OUP)

    Dr Andrew J Spiers

  19. Posters

    Article • FEBS Journal, September 2017, Wiley

    Lena Golubewa, Dr Andrew J Spiers

  20. Biofilm formation and cellulose expression by Bordetella avium 197N, the causative agent of bordetellosis in birds and an opportunistic respiratory pathogen in humans

    Article • Research in Microbiology, June 2017, Elsevier

    Dr Andrew J Spiers

  21. Adaptive radiation of Pseudomonas fluorescens SBW25 in experimental microcosms provides an understanding of the evolutionary ecology and molecular biology of A-L interface biofilm formation

    Article • FEMS Microbiology Letters, May 2017, Oxford University Press (OUP)

    Dr Andrew J Spiers

  22. Conflicting selection alters the trajectory of molecular evolution in a tripartite bacteria-plasmid-phage interaction

    Article • Molecular Ecology, April 2017, Wiley

    Dr Andrew J Spiers

  23. Viewing Biofilms within the Larger Context of Bacterial Aggregations

    Article • July 2016, IntechOpen

    Dr Andrew J Spiers

  24. Rapid compensatory evolution promotes the survival of conjugative plasmids

    Article • Mobile Genetic Elements, May 2016, Taylor & Francis

    Dr Andrew J Spiers

  25. New Insights into the Effects of Several Environmental Parameters on the Relative Fitness of a Numerically Dominant Class of Evolved Niche Specialist

    Article • International Journal of Evolutionary Biology, January 2016, Hindawi Publishing Corporation

    Dr Andrew J Spiers

  26. Plasmid carriage can limit bacteria–phage coevolution

    Article • Proceedings of the Royal Society B Biological Sciences, August 2015, Royal Society Publishing

    Dr Ellie Harrison, Dr Andrew J Spiers

  27. Parallel Compensatory Evolution Stabilizes Plasmids across the Parasitism-Mutualism Continuum

    Article • Current Biology, August 2015, Elsevier

    Dr Andrew J Spiers

  28. A role for glutathione and its biosynthetic genes in Anopheles gambiae insecticide resistance

    Article • Journal of Biotechnology, August 2015, Elsevier

    Dr Andrew J Spiers

  29. Environmentally co-occurring mercury resistance plasmids are genetically and phenotypically diverse and confer variable context-dependent fitness effects

    Article • Environmental Microbiology, June 2015, Wiley

    Dr Andrew J Spiers

  30. Bacteriophages Limit the Existence Conditions for Conjugative Plasmids

    Article • mBio, June 2015, ASM Journals

    Dr Ellie Harrison, Dr Andrew J Spiers

  31. The evolution of biofilm-forming Wrinkly Spreaders in static microcosms and drip-fed columns selects for subtle differences in wrinkleality and fitness

    Article • FEMS Microbiology Ecology, May 2015, Oxford University Press (OUP)

    Dr Andrew J Spiers

  32. Predicting the minimum liquid surface tension activity of pseudomonads expressing biosurfactants

    Article • Letters in Applied Microbiology, October 2014, Wiley

    Dr Andrew J Spiers

  33. Transparent soil microcosms allow 3D spatial quantification of soil microbiological processesin vivo

    Article • Plant Signaling & Behavior, October 2014, Taylor & Francis

    Dr Helen F Downie, Dr Andrew J Spiers

  34. Investigating the role of glutathione and glutathione biosynthetic enzymes in the adaptation of Anopheles gambiae to insecticides

    Article • Journal of Biotechnology, September 2014, Elsevier

    Dr Andrew J Spiers

  35. Quorum-Quenching Activity of the AHL-Lactonase from Bacillus licheniformis DAHB1 Inhibits Vibrio Biofilm Formation In Vitro and Reduces Shrimp Intestinal Colonisation and Mortality

    Article • Marine Biotechnology, July 2014, Springer Science + Business Media

    Dr Andrew J Spiers

  36. Getting Wrinkly Spreaders to demonstrate evolution in schools

    Article • Trends in Microbiology, June 2014, Elsevier

    Dr Andrew J Spiers

  37. A Mechanistic Explanation Linking Adaptive Mutation, Niche Change, and Fitness Advantage for the Wrinkly Spreader

    Article • International Journal of Evolutionary Biology, January 2014, Hindawi Publishing Corporation

    Dr Andrew J Spiers

  38. Cellulose Expression in Pseudomonas fluorescens SBW25 and Other Environmental Pseudomonads

    Article • August 2013, IntechOpen

    Dr Andrew J Spiers

  39. Air–liquid interface biofilm formation by psychrotrophic pseudomonads recovered from spoilt meat

    Article • Antonie van Leeuwenhoek, September 2012, Springer Science + Business Media

    Dr Andrew J Spiers

  40. Transparent Soil for Imaging the Rhizosphere

    Article • PLoS ONE, September 2012, PLOS

    Dr Andrew J Spiers

  41. Surfactants expressed by soil pseudomonads alter local soil-water distribution, suggesting a hydrological role for these compounds

    Article • FEMS Microbiology Ecology, June 2011, Oxford University Press (OUP)

    Dr Andrew J Spiers

  42. Evolution in a test tube: rise of the Wrinkly Spreaders

    Article • Journal of Biological Education, March 2011, Taylor & Francis

    Dr Andrew J Spiers

  43. Environmental modification and niche construction: developing O2 gradients drive the evolution of the Wrinkly Spreader

    Article • The ISME Journal, October 2010, Nature

    Dr Andrew J Spiers

  44. Antagonistic coevolution accelerates molecular evolution

    Article • Nature, February 2010, Springer Science + Business Media

    Dr Ben Libberton, Dr Andrew J Spiers

  45. Characterization of a novel air-liquid interface biofilm of Pseudomonas fluorescens SBW25

    Article • Microbiology, April 2009, Society for General Microbiology

    Dr Andrew J Spiers

  46. Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens

    Article • Genome Biology, January 2009, Springer Science + Business Media

    Professor Julian Parkhill, Dr Andrew J Spiers, Dr Xue-Xian Zhang

  47. Characterizing the regulation of the Pu promoter in Acinetobacter baylyi ADP1

    Article • Environmental Microbiology, July 2008, Wiley

    Dr Andrew J Spiers

  48. The minimum information about a genome sequence (MIGS) specification

    Article • Nature Biotechnology, May 2008, Springer Science + Business Media

    Professor Julian Parkhill, Dr Andrew J Spiers, Prof George M Garrity, Dr Robert A Edwards, Dr Nikos C Kyrpides

  49. Chapter 4 Microbial Distribution in Soils

    Article • January 2008, Elsevier

    Dr Andrew J Spiers

  50. Wrinkly-Spreader Fitness in the Two-Dimensional Agar Plate Microcosm: Maladaptation, Compensation and Ecological Success

    Article • PLoS ONE, August 2007, PLOS

    Dr Andrew J Spiers

  51. Sequence-based analysis of pQBR103; a representative of a unique, transfer-proficient mega plasmid resident in the microbial community of sugar beet

    Article • The ISME Journal, July 2007, Springer Science + Business Media

    Professor Julian Parkhill, Dr Andrew J Spiers, Lori Snyder, Dr Xue-Xian Zhang

  52. The structure-function relationship of WspR, a Pseudomonas fluorescens response regulator with a GGDEF output domain

    Article • Microbiology, April 2007, Society for General Microbiology

    Dr Andrew J Spiers

  53. The Environmental Plasmid pQBR103 Alters the Single-Cell Raman Spectral Profile of Pseudomonas fluorescens SBW25

    Article • Microbial Ecology, March 2007, Springer Science + Business Media

    Dr Andrew J Spiers

  54. Pseudomonas fluorescens SBW25 Biofilm and Planktonic Cells Have Differentiable Raman Spectral Profiles

    Article • Microbial Ecology, March 2007, Springer Science + Business Media

    Dr Andrew J Spiers

  55. Single-Cell Raman Spectral Profiles of Pseudomonas fluorescens SBW25 Reflects in vitro and in planta Metabolic History

    Article • Microbial Ecology, March 2007, Springer Science + Business Media

    Dr Andrew J Spiers

  56. Adaptive Divergence in Experimental Populations of Pseudomonas fluorescens. III. Mutational Origins of Wrinkly Spreader Diversity

    Article • Genetics, February 2007, Genetics Society of America

    Dr Andrew J Spiers

  57. Biofilm formation and cellulose expression among diverse environmental Pseudomonas isolates

    Article • Environmental Microbiology, November 2006, Wiley

    Dr Andrew J Spiers

  58. Consideration of Future Requirements for Raman Microbiology as an Examplar for the Ab Initio Development of Informatics Frameworks for Emergent OMICS Technologies

    Article • OMICS A Journal of Integrative Biology, June 2006, Mary Ann Liebert Inc

    Dr Andrew J Spiers

  59. Adaptive Divergence in Experimental Populations of Pseudomonas fluorescens. II. Role of the GGDEF Regulator WspR in Evolution and Development of the Wrinkly Spreader Phenotype

    Article • Genetics, April 2006, Genetics Society of America

    Dr Andrew J Spiers

  60. The Pseudomonas fluorescens SBW25 wrinkly spreader biofilm requires attachment factor, cellulose fibre and LPS interactions to maintain strength and integrity

    Article • Microbiology, September 2005, Society for General Microbiology

    Dr Andrew J Spiers

  61. Genes encoding a cellulosic polymer contribute toward the ecological success of Pseudomonas fluorescens SBW25 on plant surfaces

    Article • Molecular Ecology, September 2003, Wiley

    Dr Andrew J Spiers

  62. Biofilm formation at the air-liquid interface by the Pseudomonas fluorescens SBW25 wrinkly spreader requires an acetylated form of cellulose

    Article • Molecular Microbiology, August 2003, Wiley

    Dr Andrew J Spiers

  63. Notes on designing a partial genomic database: The PfSBW25 Encyclopaedia, a sequence database for Pseudomonas fluorescens SBW25

    Article • Microbiology, February 2001, Society for General Microbiology

    Dr Andrew J Spiers

  64. The causes of Pseudomonas diversity

    Article • Microbiology, October 2000, Society for General Microbiology

    Dr Andrew J Spiers

  65. C-terminal interactions between the XerC and XerD site-specific recombinases

    Article • Molecular Microbiology, June 1999, Wiley

    Dr Andrew J Spiers

  66. Microbial honours

    Article • Trends in Microbiology, March 1998, Elsevier

    Dr Andrew J Spiers

  67. Relating primary structure to function in the Escherichia coli XerD site-specific recombinase

    Article • Molecular Microbiology, June 1997, Wiley

    Dr Andrew J Spiers

  68. RepFIB: A Basic Replicon of Large Plasmids

    Article • Plasmid, May 1993, Elsevier

    Dr Andrew J Spiers

  69. Regulatory interactions between RepA, an essential replication protein, and the DNA repeats of RepFIB from plasmid P307.

    Article • Journal of Bacteriology, January 1993, ASM Journals

    Dr Andrew J Spiers

  70. Expression and regulation of the RepA protein of the RepFIB replicon from plasmid P307.

    Article • Journal of Bacteriology, January 1992, ASM Journals

    Dr Andrew J Spiers

  71. Nucleotide sequence and replication characteristics of RepFIB, a basic replicon of IncF plasmids.

    Article • Journal of Bacteriology, January 1989, ASM Journals

    Dr Andrew J Spiers