What is it about?
Proper pain relief is one of the primary concerns in both human and veterinary medicine due to its close ties with postoperative standard of care and patient well-being. In this context, this study was conducted to evaluate the analgesic effects of ketamine–lidocaine infusion in addition to single intravenous dose of tramadol during and after ovariohysterectomy in a dog model. Drugs were administered before the start of surgery as pre-emptive multimodal analgesia. Algometry and short form of the Glasgow composite pain scale were used to measure postoperative pain up to 72 hours. The addition of ketamine–lidocaine infusion to single intravenous dose of tramadol significantly dampened intraoperative hemodynamic responses, reduced secondary hyperalgesia, and improved postoperative analgesia.
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Why is it important?
this work reports the effects of using combination of three drugs, which have never been reported previously for the pain management after surgery. This work can help the clinicians and researchers for further research into the mechanism of pain.
Perspectives
This article is the main theme of my work. Highly important from clinical aspects for small animals practitioners as well as surgeons
Ubedullah Kaka
Universiti Putra Malaysia
Read the Original
This page is a summary of: Pre-emptive multimodal analgesia with tramadol and ketamine–lidocaine infusion for suppression of central sensitization in a dog model of ovariohysterectomy, Journal of Pain Research, April 2018, Dove Medical Press,
DOI: 10.2147/jpr.s152475.
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