What is it about?
Microbial pathogens are attacked by antimicrobial peptides (AMPs) produced by the human host. AMPs kill pathogens and recruit immune cells to the site of infection. In defense, the human fungal pathogen Candida albicans continuously cleaves and secretes a glycoprotein fragment of the surface protein Msb2, which protects against AMPs. The results suggest that shed Msb2 allows fungal colonies to persist and avoid inflammatory responses caused by AMPs.
Featured Image
Read the Original
This page is a summary of: Msb2 Shedding Protects Candida albicans against Antimicrobial Peptides, PLoS Pathogens, February 2012, PLOS,
DOI: 10.1371/journal.ppat.1002501.
You can read the full text:
Resources
Contributors
The following have contributed to this page
