What is it about?

Testing the ability of antimicrobial proteins and peptides to kill microbes in a human blood model outside the body ("in vitro")

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Why is it important?

We need new approaches to prevent and treat infection in the highly vulnerable newborn.

Perspectives

Study of candidate molecules in vitro (eg, in test tubes or cell culture) may help accelerate identification and development of promising new medicines that may have age-specific activities.

Dr Ofer Levy
Boston Children's Hospital/Precision Vaccines Program

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This page is a summary of: Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro, F1000Research, May 2018, Faculty of 1000, Ltd.,
DOI: 10.12688/f1000research.14736.1.
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