The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis

What is it about?

Idiopathic pulmonary fibrosis (IPF) and lung cancer represent progressive lung diseases with a poor prognosis. Furthermore, IPF represents a risk factor for the development of lung cancer, the incidence of lung cancer is increased in patients with IPF, and both diseases share common pathomechanistical features. Using this approach, we sought to explore a common pattern of misregulated genes to eventually detect novel therapeutic targets for IPF patients.

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