What is it about?
Large-scale mitochondrial DNA deletions will cause decrease in motility and fertility of human sperm.
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Why is it important?
Reactive oxygen species generated by metabolism may damage human sperm mitochondrial DNA.
Perspectives
To avoid oxidative stress is good for maintaining mitochondrial integrity and sperm motility and fertility.
Professor and Director Yau-Huei Wei
Changhua Christian Hospital
Read the Original
This page is a summary of: Mitochondrial Deoxyribonucleic Acid 4977-bp Deletion is Associated with Diminished Fertility and Motility of Human Sperm1, Biology of Reproduction, April 1995, Oxford University Press (OUP),
DOI: 10.1095/biolreprod52.4.729.
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