What is it about?
Databases have become central to all the biomedical sciences. This one has a focus on pharmacology and indexes thousands of chemical strcutures, including those widely used as medicines. A lot of useful information is included in these entries, including references to publications. It is also useful as an educational resource for pharmacology.
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Why is it important?
The status of the NAR Annual Databse issue is increasing not only for the informatics community of practice but also the experimentalists whose data are captured and integrated. Notably the mix includes expert curated "small data" sources, such as ours, alongside the "big data" ones at a scale that demands computational collation. Ours has a clear complementary utility "niche" amoung the other exellent resouces, some of which we have reciprocal linking with. Note that, along with download enhance ments, this release presents our Web Services debut as a step on the road to semantic inteoperability. We would also like to point out that, in accordance with editorial policy, we minimised overlap with out 2014 version (link on the right). The two papers are thus not only a complementary pair but are also concieved as adjunct to documentation on our website, including the FAQ.
Perspectives
I enjoyed the privillage of being first author this time around but this was enabled by key imputs from the team and collaborating authors. I was also pleased we were permitted a somewhat longer than usual submission (but waffle-free I hope).
Dr Christopher Southan
Read the Original
This page is a summary of: The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands, Nucleic Acids Research, October 2015, Oxford University Press (OUP),
DOI: 10.1093/nar/gkv1037.
You can read the full text:
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Contributors
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