What is it about?
This line of research supports that accumulation of mutation and oxidative damage to mitochondrial DNA is a cause of aging.
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Why is it important?
It is important to avoid oxidative stress-elicited damage and mutation of mitochondrial DNA.
Perspectives
One has to avoid overproduction of reactive oxygen species in mitochondria of somatic tissues including muscle and brain in order to live a long and healthy life.
Professor and Director Yau-Huei Wei
Changhua Christian Hospital
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This page is a summary of: Ageing and mammalian mitochondrial genetics, Trends in Genetics, December 1998, Elsevier,
DOI: 10.1016/s0168-9525(98)01580-7.
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