Comparative analysis of antimicrobial resistance genes of M. tuberculosis and M. bovis in silico

What is it about?

Tuberculosis is an infectious disease that affects human beings and animals, and is caused by members of the Mycobacterium tuberculosis Complex (MTC). Mycobacterium bovis causes bovine tuberculosis and is the main organism responsible for zoonotic tuberculosis in humans. Tuberculosis control is threatened by the emergence and spread of resistant Mycobacterium tuberculosis complex strains that affect the effectiveness of the drugs.

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Why is it important?

Determination of the common resistance genes between M. tuberculosis and M. bovis will aid in predicting proteins that can be used in designing vaccines to prevent Mycobacterium diseases.