What is it about?
In human liver, muscle and skin tissues, we detected several aging-associated mitochondrial DNA mutations.
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Why is it important?
Oxidative stress and damage elicited by metabolism may cause mitochondrial DNA mutations in affected tissues.
Perspectives
An effective antioxidant system can remove reactive oxygen species and avoid aging-associated mitochondrial mutations.
Professor and Director Yau-Huei Wei
Changhua Christian Hospital
Read the Original
This page is a summary of: Mitochondrial DNA alterations as ageing-associated molecular events, Mutation Research/DNAging, September 1992, Elsevier,
DOI: 10.1016/0921-8734(92)90019-l.
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