What is it about?
Thanks to chemical proteomics, PM has been identified as a proteasome interactor. Next, its inactivation profile over proteasome has been disclosed
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Why is it important?
A new chemical scaffold to block proteasome activity
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This page is a summary of: Chemical Proteomics Discloses Petrosapongiolide M, an Antiinflammatory Marine Sesterterpene, as a Proteasome Inhibitor, Angewandte Chemie, May 2010, Wiley,
DOI: 10.1002/ange.200907153.
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