All Stories

  1. Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis

    Article • The FASEB Journal, February 2019, Federation of American Societies For Experimental Biology (FASEB)

    Adriana Carino, Maria Chiara Monti

  2. Theonellasterone, a steroidal metabolite isolated from a Theonella sponge, protects peroxiredoxin-1 from oxidative stress reactions

    Article • Chemical Communications, January 2015, Royal Society of Chemistry

    Maria Chiara Monti

  3. Mechanistic insights on petrosaspongiolide M inhibitory effects on immunoproteasome and autophagy

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, April 2014, Elsevier

    Maria Chiara Monti, Agostino Casapullo

  4. Heteronemin, a marine sponge terpenoid, targets TDP-43, a key factor in several neurodegenerative disorders

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Maria Chiara Monti, Agostino Casapullo

  5. N-Formyl-7-amino-11-cycloamphilectene, a marine sponge metabolite, binds to tubulin and modulates microtubule depolymerization

    Article • Molecular BioSystems, January 2014, Royal Society of Chemistry

    Maria Chiara Monti, Agostino Casapullo

  6. In cell scalaradial interactome profiling using a bio-orthogonal clickable probe

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Maria Chiara Monti, Agostino Casapullo

  7. Copper Promotes TFF1-Mediated Helicobacter pylori Colonization

    Article • PLoS ONE, November 2013, PLOS

    Maria Chiara Monti, Dr Marguerite Clyne

  8. Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo

    Article • PLoS ONE, March 2013, PLOS

    Maria Chiara Monti

  9. Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Maria Chiara Monti, Agostino Casapullo

  10. The Inactivation Mechanism of Human Group IIA Phospholipase A2 by Scalaradial

    Article • ChemBioChem, September 2012, Wiley

    Maria Chiara Monti, Agostino Casapullo

  11. Plakilactones from the Marine SpongePlakinastrella mamillaris. Discovery of a New Class of Marine Ligands of Peroxisome Proliferator-Activated Receptor γ

    Article • Journal of Medicinal Chemistry, September 2012, American Chemical Society (ACS)

    Maria Chiara Monti, Agostino Casapullo

  12. Modulation of Tau Protein Fibrillization by Oleocanthal

    Article • Journal of Natural Products, September 2012, American Chemical Society (ACS)

    Maria Chiara Monti, Agostino Casapullo

  13. Chemical Proteomics Reveals Heat Shock Protein 60 To Be the Main Cellular Target of the Marine Bioactive Sesterterpene Suvanine

    Article • ChemBioChem, July 2012, Wiley

    Maria Chiara Monti, Agostino Casapullo

  14. Anti-inflammatory cyclopeptides from the marine sponge Theonella swinhoei

    Article • Tetrahedron, April 2012, Elsevier

    Maria Chiara Monti

  15. Modulation of Proteasome Machinery by Natural and Synthetic Analogues of the Marine Bioactive Compound Petrosaspongiolide M

    Article • ChemBioChem, March 2012, Wiley

    Maria Chiara Monti, Agostino Casapullo

  16. Discovery That Theonellasterol a Marine Sponge Sterol Is a Highly Selective FXR Antagonist That Protects against Liver Injury in Cholestasis

    Article • PLoS ONE, January 2012, PLOS

    Maria Chiara Monti

  17. Heat shock proteins as key biological targets of the marine natural cyclopeptide perthamide C

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Maria Chiara Monti, Agostino Casapullo

  18. Inside Cover: The Binding Mode of Cladocoran A to the Human Group IIA Phospholipase A2 (ChemBioChem 17/2011)

    Article • ChemBioChem, November 2011, Wiley

    Maria Chiara Monti, Agostino Casapullo

  19. The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, November 2011, Elsevier

    Maria Chiara Monti

  20. The Binding Mode of Cladocoran A to the Human Group IIA Phospholipase A2

    Article • ChemBioChem, September 2011, Wiley

    Maria Chiara Monti, Agostino Casapullo

  21. Structure-based design, synthesis and preliminary anti-inflammatory activity of bolinaquinone analogues

    Article • European Journal of Medicinal Chemistry, February 2011, Elsevier

    Maria Chiara Monti

  22. Chemical proteomics reveals bolinaquinone as a clathrin-mediated endocytosis inhibitor

    Article • Molecular BioSystems, January 2011, Royal Society of Chemistry

    Maria Chiara Monti, Agostino Casapullo

  23. New insights on the interaction mechanism between tau protein and oleocanthal, an extra-virgin olive-oil bioactive component

    Article • Food & Function, January 2011, Royal Society of Chemistry

    Maria Chiara Monti, Agostino Casapullo

  24. Petrosaspongiolide M inactivates proteasome in vitro and in cell assays

    Article • Angewandte Chemie, May 2010, Wiley

    Maria Chiara Monti, Agostino Casapullo

  25. Inside Cover: Chemical Proteomics Discloses Petrosapongiolide M, an Antiinflammatory Marine Sesterterpene, as a Proteasome Inhibitor (Angew. Chem. Int. Ed. 23/2010)

    Article • Angewandte Chemie, May 2010, Wiley

    Maria Chiara Monti, Agostino Casapullo

  26. Copper binds the carboxy-terminus of trefoil protein 1 (TFF1), favoring its homodimerization and motogenic activity

    Article • Cellular and Molecular Life Sciences, March 2010, Springer Science + Business Media

    Maria Chiara Monti

  27. Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei

    Article • Tetrahedron, December 2009, Elsevier

    Maria Chiara Monti

  28. The molecular mechanism of human group IIA phospholipase A2 inactivation by bolinaquinone

    Article • Journal of Molecular Recognition, July 2009, Wiley

    Maria Chiara Monti, Agostino Casapullo

  29. Effects of petrosaspongiolide R on the surface topology of bee venom PLA2: A limited proteolysis and mass spectrometry analysis

    Article • Bioorganic Chemistry, February 2009, Elsevier

    Maria Chiara Monti, Agostino Casapullo

  30. The Binding Mode of Petrosaspongiolide M to the Human Group IIA Phospholipase A2: Exploring the Role of Covalent and Noncovalent Interactions in the Inhibition Process

    Article • Chemistry - A European Journal, January 2009, Wiley

    Maria Chiara Monti, Agostino Casapullo

  31. Homophymine A, an Anti-HIV Cyclodepsipeptide from the Sponge Homophymia sp.

    Article • The Journal of Organic Chemistry, June 2008, American Chemical Society (ACS)

    Maria Chiara Monti

  32. Scalaradial, a Dialdehyde‐Containing Marine Metabolite That Causes an Unexpected Noncovalent PLA2 Inactivation

    Article • ChemBioChem, August 2007, Wiley

    Maria Chiara Monti, Agostino Casapullo

  33. Copper-binding activity of Trefoil factor 1 (TFF1): A new perspective in the study of the multifunctional roles of TFFs

    Article • Peptides, July 2007, Elsevier

    Maria Chiara Monti

  34. Structure and Function of Bacterial Kid-Kis and Related Toxin-Antitoxin Systems

    Article • Protein and Peptide Letters, February 2007, Bentham Science Publishers

    Maria Chiara Monti

  35. Interactions between the toxin Kid of the bacterial parD system and the antitoxins Kis and MazE

    Article • Proteins Structure Function and Bioinformatics, January 2007, Wiley

    Maria Chiara Monti

  36. Chemistry and Biology of Anti-Inflammatory Marine Natural Products:Molecules Interfering with Cyclooxygenase, NF-kB and Other Unidentified Targets

    Article • Current Medicinal Chemistry, July 2006, Bentham Science Publishers

    Maria Chiara Monti, Agostino Casapullo

  37. Chemistry and Biology of Antiinflammatory Marine Natural Products: Phospholipase A2 Inhibitors

    Article • ChemInform, June 2006, Wiley

    Maria Chiara Monti, Agostino Casapullo

  38. The Molecular Mechanism of Bee Venom Phospholipase A2 Inactivation by Bolinaquinone

    Article • ChemBioChem, May 2006, Wiley

    Maria Chiara Monti, Agostino Casapullo

  39. Callipeltins F—I: New Antifungal Peptides from the Marine Sponge Latrunculia sp.

    Article • ChemInform, April 2006, Wiley

    Maria Chiara Monti

  40. Model for RNA Binding and the Catalytic Site of the RNase Kid of the Bacterial parD Toxin–Antitoxin System

    Article • Journal of Molecular Biology, March 2006, Elsevier

    Maria Chiara Monti, Dr. Alexandre M.J.J. Bonvin

  41. Quantum Mechanical Calculation of Coupling Constants in the Configurational Analysis of Flexible Systems: Determination of the Configuration of Callipeltin A

    Article • European Journal of Organic Chemistry, January 2006, Wiley

    Maria Chiara Monti

  42. Callipeltins F–I: new antifungal peptides from the marine sponge Latrunculia sp.

    Article • Tetrahedron, January 2006, Elsevier

    Maria Chiara Monti

  43. Concise Synthesis of All Stereoisomers of β-Methoxytyrosine and Determination of the Absolute Configuration of the Residue in Callipeltin A

    Article • Organic Letters, July 2005, American Chemical Society (ACS)

    Maria Chiara Monti, Agostino Casapullo

  44. The inactivation of phospholipase A2 by scalaradial: a biomimetic study by electrospray mass spectrometry

    Article • Rapid Communications in Mass Spectrometry, January 2005, Wiley

    Maria Chiara Monti, Agostino Casapullo

  45. Further insights on the structural aspects of PLA2 inhibition by γ-hydroxybutenolide-containing natural products: a comparative study on petrosaspongiolides M–R

    Article • Bioorganic & Medicinal Chemistry, March 2004, Elsevier

    Maria Chiara Monti, Agostino Casapullo