What is it about?
Structural and functional analysis of telomerase, the enzyme that replicates the ends of our chromosomes. Understanding the mechanism of action of naturally occurring TERT mutations in human disease.
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Why is it important?
The study provides mechanistic insights into telomere replication by telomerase and sheds light into human disease associated with naturally occurring TERT mutations.
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This page is a summary of: TERT Structure, Function, and Molecular Mechanisms, May 2012, Wiley,
DOI: 10.1002/9781118268667.ch3.
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