All Stories

  1. Mapping Region of Human Restriction Factor APOBEC3H Critical for Interaction with HIV-1 Vif

    Article • Journal of Molecular Biology, April 2017, Elsevier

    Dr Yasumasa Iwatani

  2. APOBEC3G-Mediated G-to-A Hypermutation of the HIV-1 Genome: The Missing Link in Antiviral Molecular Mechanisms

    Article • Frontiers in Microbiology, December 2016, Frontiers

    Dr Yasumasa Iwatani

  3. Molecular epidemiology of co-infection with hepatitis B virus and human immunodeficiency virus (HIV) among adult patients in Harare, Zimbabwe

    Article • Journal of Medical Virology, August 2016, Wiley

    Dr Yasumasa Iwatani

  4. Crystal Structure of a Darunavir Resistant HIV-1 Protease

    Article • April 2016, Protein Data Bank, Rutgers University

    Dr Yasumasa Iwatani

  5. A Novel Drug-Resistant HIV-1 Circulating Recombinant Form CRF76_01B Identified by Near Full-Length Genome Analysis

    Article • AIDS Research and Human Retroviruses, March 2016, Mary Ann Liebert Inc

    Dr Yasumasa Iwatani

  6. Natural Single-Nucleotide Variations in the HIV-1 Genomic SA1prox Region Can Alter Viral Replication Ability by Regulating Vif Expression Levels

    Article • Journal of Virology, February 2016, ASM Journals

    Dr Yasumasa Iwatani

  7. Unique Flap Conformation in an HIV-1 Protease with High-Level Darunavir Resistance

    Article • Frontiers in Microbiology, February 2016, Frontiers

    Professor Nobuhisa Watanabe, Dr Yasumasa Iwatani

  8. Molecular epidemiology of enteric viruses in patients with acute gastroenteritis in Aichi prefecture, Japan, 2008/09−2013/14

    Article • Journal of Medical Virology, December 2015, Wiley

    Dr Yasumasa Iwatani

  9. APOBEC3G genotypes and proviral DNA hypermutations on HIV/AIDS disease progression in Thai and Cambodian children

    Article • Future Virology, December 2015, Future Medicine

    Dr Yasumasa Iwatani

  10. Virological characteristics of hepatitis B genotype G/A2 recombination virus in Japan

    Article • Hepatology Research, November 2015, Wiley

    Dr Yasumasa Iwatani

  11. Quasispecies Analyses of the HIV-1 Near-full-length Genome With Illumina MiSeq

    Article • Frontiers in Microbiology, November 2015, Frontiers

    Dr Yasumasa Iwatani

  12. Vif-APOBEC3F Interaction Interfaces

    Article • Journal of Virology, November 2015, ASM Journals

    Dr Yasumasa Iwatani, Professor Nobuhisa Watanabe

  13. A cell-free enzymatic activity assay for the evaluation of HIV-1 drug resistance to protease inhibitors

    Article • Frontiers in Microbiology, October 2015, Frontiers

    Dr Yasumasa Iwatani

  14. Natural polymorphism S119R of HIV-1 integrase enhances primary INSTI resistance

    Article • Antiviral Research, July 2015, Elsevier

    Dr Yasumasa Iwatani

  15. Crystal Structure of the Vif-Binding Domain of Human APOBEC3F

    Article • June 2015, Protein Data Bank, Rutgers University

    Dr Yasumasa Iwatani

  16. Mutational analysis of HIV-2 Vpx shows that proline residue 109 in the poly-proline motif regulates degradation of SAMHD1

    Article • FEBS Letters, April 2015, Wiley

    Dr Yasumasa Iwatani

  17. APOBEC3H polymorphisms associated with the susceptibility to HIV-1 infection and AIDS progression in Japanese

    Article • Immunogenetics, February 2015, Springer Science + Business Media

    Dr Yasumasa Iwatani

  18. Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities

    Article • Retrovirology, January 2015, Springer Science + Business Media

    Dr Yasumasa Iwatani

  19. Phylodynamic Analysis Reveals CRF01_AE Dissemination between Japan and Neighboring Asian Countries and the Role of Intravenous Drug Use in Transmission

    Article • PLoS ONE, July 2014, PLOS

    Dr Yasumasa Iwatani

  20. APOBEC3G and G-to-A hypermutation in Asian children with different HIV/AIDS disease progression

    Article • International Journal of Infectious Diseases, April 2014, Elsevier

    Dr Yasumasa Iwatani

  21. Lack of Association between Intact/Deletion Polymorphisms of the APOBEC3B Gene and HIV-1 Risk

    Article • PLoS ONE, March 2014, PLOS

    Dr Yasumasa Iwatani

  22. Oligomerization transforms human APOBEC3G from an efficient enzyme to a slowly dissociating nucleic acid-binding protein

    Article • Nature Chemistry, November 2013, Nature

    Dr Yasumasa Iwatani

  23. Poly-proline motif in HIV-2 Vpx is critical for its efficient translation

    Article • Journal of General Virology, October 2013, Society for General Microbiology

    Dr Yasumasa Iwatani

  24. Generation of Rhesus Macaque-Tropic HIV-1 Clones That Are Resistant to Major Anti-HIV-1 Restriction Factors

    Article • Journal of Virology, August 2013, ASM Journals

    Dr Hironori Sato, Dr Yasumasa Iwatani

  25. TRIM5 genotypes in cynomolgus monkeys primarily influence inter-individual diversity in susceptibility to monkey-tropic human immunodeficiency virus type 1

    Article • Journal of General Virology, March 2013, Society for General Microbiology

    Dr Yasumasa Iwatani

  26. Zinc finger function of HIV-1 nucleocapsid protein is required for removal of 5′-terminal genomic RNA fragments: A paradigm for RNA removal reactions in HIV-1 reverse transcription

    Article • Virus Research, February 2013, Elsevier

    Dr Yasumasa Iwatani

  27. Multifunctional HIV accessory proteins are hub proteins antagonizing host antiviral factors

    Article • Uirusu, January 2013, Japanese Association of Virology

    Dr Yasumasa Iwatani

  28. Crystal Structure of the Human APOBEC3C having HIV-1 Vif-binding Interface

    Article • October 2012, Protein Data Bank, Rutgers University

    Dr Yasumasa Iwatani

  29. Crystal structure of the human APOBEC3C having HIV-1 Vif-binding interface

    Article • October 2012, Protein Data Bank, Rutgers University

    Dr Yasumasa Iwatani

  30. The APOBEC3C crystal structure and the interface for HIV-1 Vif binding

    Article • Nature Structural & Molecular Biology, September 2012, Nature

    Professor Nobuhisa Watanabe, Dr Yasumasa Iwatani

  31. Outbreak of Infections by Hepatitis B Virus Genotype A and Transmission of Genetic Drug Resistance in Patients Coinfected with HIV-1 in Japan

    Article • Journal of Clinical Microbiology, March 2012, ASM Journals

    Dr Yasumasa Iwatani

  32. Two Genetic Determinants Acquired Late in Mus Evolution Regulate the Inclusion of Exon 5, which Alters Mouse APOBEC3 Translation Efficiency

    Article • PLoS Pathogens, January 2012, PLOS

    Dr Yasumasa Iwatani, Masaaki Miyazawa

  33. Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 Family

    Article • Frontiers in Microbiology, January 2012, Frontiers

    Dr Yasumasa Iwatani

  34. Oligomerization of HIV-1 Restriction Factor APOBEC3G Transforms it from a Fast Enzyme to a Slow Nucleic Acid Binding Protein

    Article • Biophysical Journal, January 2012, Elsevier

    Dr Yasumasa Iwatani

  35. Within-host co-evolution of Gag P453L and protease D30N/N88D demonstrates virological advantage in a highly protease inhibitor-exposed HIV-1 case

    Article • Antiviral Research, April 2011, Elsevier

    Dr Yasumasa Iwatani

  36. Complex Kinetics of Apobec3g Interaction with Single-Stranded Nucleic Acids

    Article • Biophysical Journal, February 2011, Elsevier

    Dr Yasumasa Iwatani

  37. Outbreak of Infections by Hepatitis B Virus Genotype A and Transmission of Genetic Drug Resistance in Patients Coinfected with HIV-1 in Japan

    Article • Journal of Clinical Microbiology, January 2011, ASM Journals

    Dr Yasumasa Iwatani

  38. Mechanisms for Inhibition of Retrovirus Replication by APOBEC3 Family

    Article • Uirusu, January 2011, Japanese Association of Virology

    Dr Yasumasa Iwatani

  39. Structural Features of Antiviral APOBEC3 Proteins are Linked to Their Functional Activities

    Article • Frontiers in Microbiology, January 2011, Frontiers

    Dr Yasumasa Iwatani

  40. HIV-2 CRF01_AB: First Circulating Recombinant Form of HIV-2

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, July 2010, Wolters Kluwer Health

    Dr Yasumasa Iwatani

  41. Nucleic Acid Interaction Kinetics of APOBEC3G Investigated Using Ensemble and Single Molecule Methods

    Article • Biophysical Journal, January 2010, Elsevier

    Dr Yasumasa Iwatani

  42. HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain

    Article • Proceedings of the National Academy of Sciences, November 2009, Proceedings of the National Academy of Sciences

    Dr Yasumasa Iwatani

  43. Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G

    Article • Nucleic Acids Research, November 2007, Oxford University Press (OUP)

    Dr Yasumasa Iwatani

  44. Biochemical Activities of Highly Purified, Catalytically Active Human APOBEC3G: Correlation with Antiviral Effect

    Article • Journal of Virology, June 2006, ASM Journals

    Dr Yasumasa Iwatani, Dr Hiroaki Takeuchi

  45. Monomeric APOBEC3G Is Catalytically Active and Has Antiviral Activity

    Article • Journal of Virology, May 2006, ASM Journals

    Dr Yasumasa Iwatani, Dr Hiroaki Takeuchi

  46. Efficient Initiation of HIV-1 Reverse Transcriptionin Vitro: REQUIREMENT FOR RNA SEQUENCES DOWNSTREAM OF THE PRIMER BINDING SITE ABROGATED BY NUCLEOCAPSID PROTEIN-DEPENDENT PRIMER-TEMPLATE INTERACTIONS

    Article • Journal of Biological Chemistry, January 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Yasumasa Iwatani

  47. A thiol proteinase inhibitor, E-64-d, corrects the abnormalities in concanavalin A cap formation and the lysosomal enzyme activity in leucocytes from patients with Chediak-Higashi syndrome by reversing the down-regulated protein kinase C activity

    Article • Clinical & Experimental Immunology, August 2001, Wiley

    Dr Yasumasa Iwatani

  48. Analysis of Dominant-Negative Effects of Mutant Env Proteins of Human Immunodeficiency Virus Type 1

    Article • Virology, July 2001, Elsevier

    Dr Yasumasa Iwatani

  49. Glycyrrhizin enhances interleukin-12 production in peritoneal macrophages

    Article • Immunology, June 2001, Wiley

    Dr Yasumasa Iwatani

  50. Modification of virus infectivity by cytoplasmic tail of HIV-1 TM protein

    Article • Virus Research, April 2001, Elsevier

    Dr Yasumasa Iwatani

  51. Resistance to Friend Murine Leukemia Virus Infection Conferred by the Fv-4 Gene Is Recessive but Appears Dominant from the Effect of the Immune System

    Article • Journal of Virology, July 2000, ASM Journals

    Dr Yasumasa Iwatani

  52. Interleukin 18 and Interleukin 1 beta Production Is Decreased in HIV Type 1-Seropositive Hemophiliacs but Not in HIV Type 1-Seropositive Nonhemophiliacs

    Article • AIDS Research and Human Retroviruses, March 2000, Mary Ann Liebert Inc

    Dr Yasumasa Iwatani

  53. Functional association between thenefgene product andgag-polregion of HIV-1

    Article • FEBS Letters, January 2000, Wiley

    Dr Yasumasa Iwatani

  54. Phosphorothioate Hammerhead Ribozymes Targeting a Conserved Sequence in the V3 Loop Region Inhibit HIV-1 Entry

    Article • Antisense and Nucleic Acid Drug Development, December 1998, Mary Ann Liebert Inc

    Dr Yasumasa Iwatani

  55. Human immunodeficiency virus type 1 Vpu modifies viral cytopathic effect through augmented virus release.

    Article • Journal of General Virology, April 1997, Society for General Microbiology

    Dr Yasumasa Iwatani

  56. A sustained increase in β-adrenoceptors during long-term therapy with metoprolol and bisoprolol in patients with heart failure from idiopathic dilated cardiomyopathy

    Article • Life Sciences, April 1996, Elsevier

    Dr Yasumasa Iwatani

  57. Shedding of Gs Protein (A Soluble Form of the Viral Glycoprotein) by the Rabies Virus-Infected BHK-21 Cells

    Article • Virology, August 1993, Elsevier

    Dr Yasumasa Iwatani