All Stories

  1. Development of original metabolically stable apelin-17 analogs with diuretic and cardiovascular effects

    Article • The FASEB Journal, November 2016, Federation of American Societies For Experimental Biology (FASEB)

    Dr Dominique Bonnet, Dr Xavier Iturrioz

  2. Convenient Access to Fluorescent Probes by Chemoselective Acylation of Hydrazinopeptides: Application to the Synthesis of the First Far-Red Ligand for Apelin Receptor Imaging

    Article • Chemistry - A European Journal, December 2015, Wiley

    Dr Xavier Iturrioz

  3. Directed Molecular Evolution of an Engineered Gammaretroviral Envelope Protein with Dual Receptor Use Shows Stable Maintenance of Both Receptor Specificities

    Article • Journal of Virology, November 2015, ASM Journals

    Dr Xavier Iturrioz

  4. SDHD Immunohistochemistry: A New Tool to ValidateSDHxMutations in Pheochromocytoma/Paraganglioma

    Article • The Journal of Clinical Endocrinology & Metabolism, February 2015, Endocrine Society

    Dr Xavier Iturrioz

  5. New structural insights into the apelin receptor: identification of key residues for apelin binding

    Article • The FASEB Journal, October 2014, Federation of American Societies For Experimental Biology (FASEB)

    Dr Xavier Iturrioz

  6. A new strategy for treating hypertension by blocking the activity of the brain renin–angiotensin system with aminopeptidase A inhibitors

    Article • Clinical Science, August 2014, Portland Press Ltd.

    Dr Xavier Iturrioz

  7. Structure–Activity Relationship Studies toward the Discovery of Selective Apelin Receptor Agonists

    Article • Journal of Medicinal Chemistry, April 2014, American Chemical Society (ACS)

    Dr Dominique Bonnet, Dr Xavier Iturrioz

  8. Glutamyl Aminopeptidase

    Article • January 2013, Elsevier

    Dr Xavier Iturrioz

  9. Apelin

    Article • January 2013, Elsevier

    Dr Xavier Iturrioz

  10. Multiple Cross Talk between Angiotensin II, Bradykinin, and Insulin Signaling in the Cortical Thick Ascending Limb of Rat Kidney

    Article • Endocrinology, July 2010, Endocrine Society

    Dr Xavier Iturrioz

  11. Identification of Threonine 348 as a Residue Involved in Aminopeptidase A Substrate Specificity

    Article • Journal of Biological Chemistry, February 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Xavier Iturrioz

  12. Apelin

    Article • January 2009, Elsevier

    Dr Xavier Iturrioz

  13. Asp 218 participates with Asp 213 to bind a Ca 2+ atom into the S1 subsite of aminopeptidase A: a key element for substrate specificity

    Article • Biochemical Journal, November 2008, Portland Press Ltd.

    Dr Xavier Iturrioz

  14. Human brain aminopeptidase A: biochemical properties and distribution in brain nuclei

    Article • Journal of Neurochemistry, July 2008, Wiley

    Dr Xavier Iturrioz

  15. Functional dissociation between apelin receptor signaling and endocytosis: implications for the effects of apelin on arterial blood pressure

    Article • Journal of Hypertension, December 2007, Wolters Kluwer Health

    Dr Xavier Iturrioz

  16. PKCζII is a target for degradation through the tumour suppressor protein pVHL

    Article • FEBS Letters, March 2007, Wiley

    Dr Xavier Iturrioz

  17. The von Hippel–Lindau tumour-suppressor protein interaction with protein kinase Cδ

    Article • Biochemical Journal, July 2006, Portland Press Ltd.

    Dr Xavier Iturrioz

  18. Apelin: Discovery, Distribution, and Physiological Role

    Article • January 2006, Elsevier

    Dr Xavier Iturrioz

  19. Tyrosine Kinase and Mitogen-Activated Protein Kinase/Extracellularly Regulated Kinase Differentially Regulate Intracellular Calcium Concentration Responses to Angiotensin II/III and Bradykinin in Rat Cortical Thick Ascending Limb

    Article • Endocrinology, January 2006, Endocrine Society

    Dr Xavier Iturrioz

  20. Role of angiotensin III in hypertension

    Article • Current Hypertension Reports, March 2005, Springer Science + Business Media

    Dr Xavier Iturrioz

  21. Functional dissociation of apelin receptor signaling and endocytosis: implications for the effects of apelin on arterial blood pressure

    Article • Journal of Neurochemistry, September 2004, Wiley

    Dr Xavier Iturrioz

  22. Aminopeptidase Inhibitors as Anti-Hypertensive Drugs

    Article • January 2004, Springer Science + Business Media

    Dr Xavier Iturrioz

  23. Contribution of Molecular Modeling and Site-Directed Mutagenesis to the Identification of a New Residue, Glutamate 215, Involved in the Exopeptidase Specificity of Aminopeptidase A †

    Article • Biochemistry, December 2003, American Chemical Society (ACS)

    Dr Xavier Iturrioz

  24. Protein Kinase C Protein Interactions

    Article • January 2003, Elsevier

    Dr Xavier Iturrioz

  25. Phosphorylation is required for PMA- and cell-cycle-induced degradation of protein kinase Cδ

    Article • Biochemical Journal, November 2002, Portland Press Ltd.

    Dr Xavier Iturrioz

  26. Study of Asparagine 353 in Aminopeptidase A:  Characterization of a Novel Motif (GXMEN) Implicated in Exopeptidase Specificity of Monozinc Aminopeptidases

    Article • Biochemistry, December 2001, American Chemical Society (ACS)

    Dr Xavier Iturrioz

  27. STRUCTURE-FUNCTION RELATIONSHIPS OF AMINOPEPTIDASE A

    Article • Biochemical Society Transactions, June 2000, Portland Press Ltd.

    Dr Xavier Iturrioz

  28. Histidine 450 Plays a Critical Role in Catalysis and, with Ca 2+ , Contributes to the Substrate Specificity of Aminopeptidase A

    Article • Biochemistry, March 2000, American Chemical Society (ACS)

    Dr Xavier Iturrioz

  29. A glutamate residue contributes to the exopeptidase specificity in aminopeptidase A

    Article • Biochemical Journal, September 1998, Portland Press Ltd.

    Dr Xavier Iturrioz

  30. A tyrosine residue essential for catalytic activity in aminopeptidase A

    Article • Biochemical Journal, November 1997, Portland Press Ltd.

    Dr Xavier Iturrioz

  31. Apelin and Vasopressin

    Article • Wiley

    Dr Xavier Iturrioz