All Stories

  1. Improved oxidation of aromatic and aliphatic hydrocarbons using rate enhancing variants of P450Bm3 in combination with decoy molecules

    Article • Chemical Communications, January 2016, Royal Society of Chemistry

    Dr Stephen G Bell

  2. The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from Bacillus subtilis

    Article • Molecular BioSystems, January 2015, Royal Society of Chemistry

    Dr Stephen G Bell, Dr Max J Cryle

  3. CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Dr Stephen G Bell

  4. The structure of a novel electron-transfer ferredoxin fromRhodopseudomonas palustrisHaA2 which contains a histidine residue in its iron–sulfur cluster-binding motif

    Article • Acta Crystallographica Section D Biological Crystallography, April 2014, International Union of Crystallography

    Dr Stephen G Bell

  5. Selective aliphatic carbon–hydrogen bond activation of protected alcohol substrates by cytochrome P450 enzymes

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Dr Stephen G Bell

  6. The dynamics of camphor in the cytochrome P450 CYP101D2

    Article • Protein Science, August 2013, Wiley

    Dr Stephen G Bell

  7. A phthalate family oxygenase reductase supports terpene alcohol oxidation by CYP238A1 fromPseudomonas putidaKT2440

    Article • Biotechnology and Applied Biochemistry, January 2013, Wiley

    Dr Stephen G Bell

  8. Investigation of the Substrate Range of CYP199A4: Modification of the Partition between Hydroxylation and Desaturation Activities by Substrate and Protein Engineering

    Article • Chemistry - A European Journal, November 2012, Wiley

    Dr Stephen G Bell

  9. Improving the affinity and activity of CYP101D2 for hydrophobic substrates

    Article • Applied Microbiology and Biotechnology, July 2012, Springer Science + Business Media

    Dr Stephen G Bell

  10. ChemInform Abstract: P450BM3(CYP102A1): Connecting the Dots

    Article • ChemInform, March 2012, Wiley

    Dr Stephen G Bell

  11. Structure and function of CYP108D1 fromNovosphingobium aromaticivoransDSM12444: an aromatic hydrocarbon-binding P450 enzyme

    Article • Acta Crystallographica Section D Biological Crystallography, February 2012, International Union of Crystallography

    Dr Stephen G Bell

  12. Tailoring an alien ferredoxin to support native-like P450 monooxygenase activity

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Dr Stephen G Bell

  13. Characterisation of the paramagnetic [2Fe–2S]+ centre in palustrisredoxin-B (PuxB) from Rhodopseudomonas palustris CGA009: g-matrix determination and spin coupling analysis

    Article • Physical Chemistry Chemical Physics, January 2012, Royal Society of Chemistry

    Dr Stephen G Bell

  14. P450BM3(CYP102A1): connecting the dots

    Article • Chemical Society Reviews, January 2012, Royal Society of Chemistry

    Dr Stephen G Bell

  15. The crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding site

    Article • Dalton Transactions, January 2012, Royal Society of Chemistry

    Dr Stephen G Bell

  16. Iron: Heme Proteins, Mono- & DioxygenasesBased in part on the article Iron: Heme Proteins, Mono- & Dioxygenases by Masanori Sono & John H. Dawson which appeared in theEncyclopedia of Inorganic Chemistry, First Edition.

    Article • December 2011, Wiley

    Dr Stephen G Bell

  17. Chain length-dependent cooperativity in fatty acid binding and oxidation by cytochrome P450BM3 (CYP102A1)

    Article • Protein & Cell, August 2011, Springer Science + Business Media

    Dr Stephen G Bell

  18. Crystallization and preliminary X-ray analysis of CYP153C1 fromNovosphingobium aromaticivoransDSM12444

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, July 2011, International Union of Crystallography

    Dr Stephen G Bell

  19. Dearomatisation of o-Xylene by P450BM3 (CYP102A1)

    Article • Chemistry - A European Journal, April 2011, Wiley

    Dr Stephen G Bell

  20. Crystal structure of the A330P mutant of cytochrome P450 BM3

    Article • March 2011, Protein Data Bank, Rutgers University

    Dr Stephen G Bell

  21. Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450BM3) variant

    Article • Dalton Transactions, January 2011, Royal Society of Chemistry

    Dr Stephen G Bell

  22. The structure of CYP101D2 unveils a potential path for substrate entry into the active site

    Article • Biochemical Journal, January 2011, Portland Press Ltd.

    Dr Stephen G Bell

  23. Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444

    Article • ChemBioChem, December 2010, Wiley

    Dr Stephen G Bell

  24. Structural Basis for the Properties of Two Single-Site Proline Mutants of CYP102A1 (P450BM3)

    Article • ChemBioChem, November 2010, Wiley

    Dr Stephen G Bell

  25. Crystal Structure of Cytochrome P450 CYP101D2

    Article • November 2010, Protein Data Bank, Rutgers University

    Dr Stephen G Bell

  26. Structural and Biochemical Characterization of the Cytochrome P450 CypX (CYP134A1) from Bacillus subtilis : A Cyclo- l -leucyl- l -leucyl Dipeptide Oxidase

    Article • Biochemistry, August 2010, American Chemical Society (ACS)

    Dr Stephen G Bell, Dr Max J Cryle

  27. Crystal Structure of Cytochrome P450 CYP101D1

    Article • June 2010, Protein Data Bank, Rutgers University

    Dr Stephen G Bell

  28. Crystal structure of a ferredoxin reductase for the CYP199A2 system from Rhodopseudomonas palustris

    Article • Proteins Structure Function and Bioinformatics, December 2009, Wiley

    Dr Stephen G Bell

  29. Protein recognition in ferredoxin–P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris

    Article • JBIC Journal of Biological Inorganic Chemistry, November 2009, Springer Science + Business Media

    Dr Stephen G Bell

  30. A cytochrome P450 class I electron transfer system from Novosphingobium aromaticivorans

    Article • Applied Microbiology and Biotechnology, September 2009, Springer Science + Business Media

    Dr Stephen G Bell

  31. A Highly Active Single-Mutation Variant of P450BM3(CYP102A1)

    Article • ChemBioChem, July 2009, Wiley

    Dr Stephen G Bell

  32. ChemInform Abstract: The Metallothionein/Thionein System: An Oxidoreductive Metabolic Zinc Link

    Article • ChemInform, April 2009, Wiley

    Dr Stephen G Bell

  33. Purification, crystallization and preliminary X-ray analysis of cytochrome P450 219A1 fromNovosphingobium aromaticivoransDSM 12444

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, March 2009, International Union of Crystallography

    Dr Stephen G Bell

  34. The Metallothionein/Thionein System: An Oxidoreductive Metabolic Zinc Link

    Article • ChemBioChem, January 2009, Wiley

    Dr Stephen G Bell

  35. Selective oxidative demethylation of veratric acid to vanillic acid by CYP199A4 from Rhodopseudomonas palustris HaA2

    Article • Molecular BioSystems, January 2009, Royal Society of Chemistry

    Dr Stephen G Bell

  36. Desaturation of Alkylbenzenes by Cytochrome P450 BM3 (CYP102A1)

    Article • Chemistry - A European Journal, December 2008, Wiley

    Dr Stephen G Bell

  37. Crystal Structure of CYP199A2, a Para-Substituted Benzoic Acid Oxidizing Cytochrome P450 from Rhodopseudomonas palustris

    Article • Journal of Molecular Biology, November 2008, Elsevier

    Dr Stephen G Bell

  38. Purification, Crystallization and Preliminary Crystallographic Analysis of CYP 195A2, a P450 Enzyme from Rhodopseudomonas palustris

    Article • Protein and Peptide Letters, May 2008, Bentham Science Publishers

    Dr Stephen G Bell

  39. Evolved CYP102A1 (P450BM3) variants oxidise a range of non-natural substrates and offer new selectivity options

    Article • Chemical Communications, January 2008, Royal Society of Chemistry

    Dr Stephen G Bell

  40. The electrochemistry of a heme-containing enzyme, CYP199A2, adsorbed directly onto a pyrolytic graphite electrode

    Article • Journal of Electroanalytical Chemistry, December 2007, Elsevier

    Dr Stephen G Bell

  41. P450 enzymes from the bacterium Novosphingobium aromaticivorans

    Article • Biochemical and Biophysical Research Communications, August 2007, Elsevier

    Dr Stephen G Bell

  42. Design and Engineering of Cytochrome P450 Systems

    Article • May 2007, Wiley

    Dr Stephen G Bell

  43. Crystallization and preliminary X-ray diffraction studies of a ferredoxin reductase fromRhodopseudomonas palustrisCGA009

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, April 2007, International Union of Crystallography

    Dr Stephen G Bell

  44. Purification, crystallization and preliminary crystallographic analysis of cytochrome P450 203A1 fromRhodopseudomonas palustris

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, March 2007, International Union of Crystallography

    Dr Stephen G Bell

  45. Iron: Heme Proteins, Mono- & DioxygenasesBased in part on the article Iron: Heme Proteins, Mono- & Dioxygenases by Masanori Sono & John H. Dawson which appeared in theEncyclopedia of Inorganic Chemistry, First Edition.

    Article • March 2006, Wiley

    Dr Stephen G Bell

  46. Cytochrome P450 enzymes from the metabolically diverse bacterium Rhodopseudomonas palustris

    Article • Biochemical and Biophysical Research Communications, March 2006, Elsevier

    Dr Stephen G Bell

  47. The Heme Monooxygenase Cytochrome P450cam Can Be Engineered to Oxidize Ethane to Ethanol

    Article • Angewandte Chemie, June 2005, Wiley

    Dr Stephen G Bell

  48. The Heme Monooxygenase Cytochrome P450cam Can Be Engineered to Oxidize Ethane to Ethanol

    Article • Angewandte Chemie International Edition, June 2005, Wiley

    Dr Stephen G Bell

  49. Biotransformation of the Sesquiterpene (+)-Valencene (I) by Cytochrome P450cam and P450BM-3

    Article • ChemInform, June 2005, Wiley

    Dr Stephen G Bell

  50. Separation of Electron-Transfer and Coupled Chemical Reaction Components of Biocatalytic Processes Using Fourier Transform ac Voltammetry

    Article • Analytical Chemistry, June 2005, American Chemical Society (ACS)

    Dr Stephen G Bell

  51. Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3

    Article • Organic & Biomolecular Chemistry, January 2005, Royal Society of Chemistry

    Dr Stephen G Bell

  52. The electrochemistry and scanning tunnelling microscopy of the flavoprotein putidaredoxin reductase on alkanethiol-modified gold

    Article • Inorganica Chimica Acta, December 2003, Elsevier

    Dr Stephen G Bell

  53. Redox properties of cytochrome P450BM3measured by direct methods

    Article • European Journal of Biochemistry, September 2003, Wiley

    Dr Stephen G Bell

  54. Engineering cytochrome P450cam into an alkane hydroxylase

    Article • Dalton Transactions, January 2003, Royal Society of Chemistry

    Dr Stephen G Bell

  55. Molecular Recognition in (+)-α-Pinene Oxidation by Cytochrome P450 cam

    Article • Journal of the American Chemical Society, January 2003, American Chemical Society (ACS)

    Dr Stephen G Bell

  56. Butane and propane oxidation by engineered cytochrome P450cam

    Article • Chemical Communications, February 2002, Royal Society of Chemistry

    Dr Stephen G Bell

  57. Engineering the haem monooxygenase cytochrome P450cam for monoterpene oxidation

    Article • Chemical Communications, January 2001, Royal Society of Chemistry

    Dr Stephen G Bell

  58. Selective aliphatic and aromatic carbon-hydrogen bond activation catalysed by mutants of cytochrome p450cam

    Article • Journal of Molecular Catalysis B Enzymatic, October 1997, Elsevier

    Dr Stephen G Bell

  59. Aliphatic vs. aromatric C–H bond activation of phenylcyclohexane catalysed by cytochrome P450cam

    Article • Chemical Communications, January 1996, Royal Society of Chemistry

    Dr Stephen G Bell

  60. Cytochrome P-450cam monooxygenase can be redesigned to catalyse the regioselective aromatic hydroxylation of diphenylmethane

    Article • Journal of the Chemical Society Chemical Communications, January 1994, Royal Society of Chemistry

    Dr Stephen G Bell

  61. The Bacterial Cytochrome P450 Monooxygenases: P450cam and P450BM-3

    Article • Wiley

    Dr Stephen G Bell