All Stories

  1. Initial Development of Automated Machine Learning-Assisted Prediction Tools for Aryl Hydrocarbon Receptor Activators
  2. Protective Effect of Indole-3-Aldehyde in Murine COVID-19-Associated Pulmonary Aspergillosis
  3. The immune and microbial homeostasis determines theCandida–mast cells cross-talk in celiac disease
  4. A Stable Micellar Formulation of RAD001 for Intracerebroventricular Delivery and the Treatment of Alzheimer’s Disease and Other Neurological Disorders
  5. Engineering carrier nanoparticles with biomimetic moieties for improved intracellular targeted delivery of mRNA therapeutics and vaccines
  6. A Thermostable Micellar Formulation of Rapalogs for Intracerebroventricular Delivery and the Therapy of Neurological Disorders
  7. Evaluation of β-Lactamase Enzyme Activity in Outer Membrane Vesicles (OMVs) Isolated from Extended Spectrum β-Lactamase (ESBL) Salmonella Infantis Strains
  8. Boosting Immunity and Management against Wheat Fusarium Diseases by a Sustainable, Circular Nanostructured Delivery Platform
  9. Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract
  10. Preface
  11. Sustainable Protocols for Cellulose Nanocrystals Synthesis from Tomato Waste and Their Antimicrobial Properties against Pseudomonas syringae pv. tomato
  12. Extracellular Vesicles in Aging: An Emerging Hallmark?
  13. Turning Microbial AhR Agonists into Therapeutic Agents via Drug Delivery Systems
  14. Biodrug Delivery Systems: Do mRNA Lipid Nanoparticles Come of Age?
  15. Development of a new indole derivative dry powder for inhalation for the treatment of biofilm-associated lung infections
  16. Pulmonary drug delivery technology enables anakinra repurposing in cystic fibrosis
  17. Development and Pharmacokinetics of a Novel Acetylsalicylic Acid Dry Powder for Pulmonary Administration
  18. Aryl Hydrocarbon Receptor Agonism Antagonizes the Hypoxia-driven Inflammation in Cystic Fibrosis
  19. Pharmaceutically Active Microbial AhR Agonists as Innovative Biodrugs in Inflammation
  20. Circular Hazelnut Protection by Lignocellulosic Waste Valorization for Nanopesticides Development
  21. Optimizing therapeutic outcomes of immune checkpoint blockade by a microbial tryptophan metabolite
  22. Preface
  23. Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy
  24. Effects of Titanium Dioxide Nanoparticles on Porcine Prepubertal Sertoli Cells: An “In Vitro” Study
  25. SBA15-supported nano-ruthenium catalyst for the oxidative cleavage of alkenes to aldehydes under flow conditions
  26. Drug-Induced Lysosomal Impairment Is Associated with the Release of Extracellular Vesicles Carrying Autophagy Markers
  27. Defective Glyoxalase 1 Contributes to Pathogenic Inflammation in Cystic Fibrosis
  28. Preface
  29. Dry Powder Inhalers in the Digitalization Era: Current Status and Future Perspectives
  30. Development and in vitro-in vivo performances of an inhalable indole-3-carboxaldehyde dry powder to target pulmonary inflammation and infection
  31. Rojo Duro Red Onion Extract Loaded Spray Thermogel as a Sustainable Platform for the Treatment of Oral Mucosa Lesions
  32. A Green Nanostructured Pesticide to Control Tomato Bacterial Speck Disease
  33. Pharyngeal Microbial Signatures Are Predictive of the Risk of Fungal Pneumonia in Hematologic Patients
  34. Indole-3-Carboxaldehyde Restores Gut Mucosal Integrity and Protects from Liver Fibrosis in Murine Sclerosing Cholangitis
  35. Targeted Drug Delivery Technologies Potentiate the Overall Therapeutic Efficacy of an Indole Derivative in a Mouse Cystic Fibrosis Setting
  36. Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity
  37. Regulation of host physiology and immunity by microbial indole-3-aldehyde
  38. Enteric formulated indole-3-carboxaldehyde targets the aryl hydrocarbon receptor for protection in a murine model of metabolic syndrome
  39. Ethidium bromide exposure unmasks an antibiotic efflux system in Rhodococcus equi
  40. Tackling Immune Pathogenesis of COVID-19 through Molecular Pharmaceutics
  41. Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
  42. Optimized Extraction of Amikacin from Murine Whole Blood
  43. Initial In Vivo Evaluation of a Novel Amikacin-Deoxycholate Hydrophobic Salt Delivers New Insights on Amikacin Partition in Blood and Tissues
  44. In “Vitro” Lps-Stimulated Sertoli Cells Pre-Loaded With Microparticles: Intracellular Activation Pathways
  45. Selectively targeting key inflammatory pathways in cystic fibrosis
  46. Evolutionary Algorithms in Modeling Aerodynamic Properties of Spray-Dried Microparticulate Systems
  47. Meet Our Editorial Board Member
  48. Preface
  49. Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity
  50. Postbiotic-Enabled Targeting of the Host-Microbiota-Pathogen Interface: Hints of Antibiotic Decline?
  51. Tryptophan as a Central Hub for Host/Microbial Symbiosis
  52. An Inhalable Theranostic System for Local Tuberculosis Treatment Containing an Isoniazid Loaded Metal Organic Framework Fe-MIL-101-NH2—From Raw MOF to Drug Delivery System
  53. Phenotypic Characterization of Rhodococcus equi Biofilm Grown In Vitro and Inhibiting and Dissolving Activity of Azithromycin/Rifampicin Treatment
  54. Development and characterization of mucoadhesive-thermoresponsive gels for the treatment of oral mucosa diseases
  55. Preface
  56. Meeting the unmet: from traditional to cutting-edge techniques for poly lactide and poly lactide-co-glycolide microparticle manufacturing
  57. Exploring the Nano Spray-Drying Technology as an Innovative Manufacturing Method for Solid Lipid Nanoparticle Dry Powders
  58. Early intrathecal infusion of everolimus restores cognitive function and mood in a murine model of Alzheimer's disease
  59. Probing Internalization Effects and Biocompatibility of Ultrasmall Zirconium Metal-Organic Frameworks UiO-66 NP in U251 Glioblastoma Cancer Cells
  60. A Novel Stabilizing Approach to Improve the Manufacturing of Biodegradable Microparticles Entrapping Plasticizing Active Molecules: the Case of 4-Methoxychalcone
  61. Development of Novel Indole-3-Aldehyde–Loaded Gastro-Resistant Spray-Dried Microparticles for Postbiotic Small Intestine Local Delivery
  62. In vitro performances of novel co-spray-dried azithromycin/rifampicin microparticles for Rhodococcus equi disease treatment
  63. Reply to ‘F508del-CFTR is not corrected by thymosin α1’
  64. Testosterone and FSH modulate Sertoli cell extracellular secretion: Proteomic analysis
  65. Crystallization
  66. Physical Properties Characterization
  67. Biopharmaceutical Processes
  68. Particle Size Measurement
  69. Pharmaceutical Powder and Particles
  70. Solid-State Chemistry
  71. General Conclusion
  72. Introduction
  73. Towards Targeting the Aryl Hydrocarbon Receptor in Cystic Fibrosis
  74. Fundamentals of Particle Interactions
  75. Particle Size and Distribution
  76. Recent and Evolving Manufacturing Processes
  77. Extracellular vesicles released by fibroblasts undergoing H-Ras induced senescence show changes in lipid profile
  78. Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms
  79. TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells
  80. The long and winding road to inhaled TB therapy: not only the bug’s fault
  81. Extremely Active, Tunable, and pH-Responsive Iridium Water Oxidation Catalysts
  82. Ion Pairing for Controlling Drug Delivery
  83. Rapamycin-loaded solid lipid nanoparticles: Morphology and impact of the drug loading on the phase transition between lipid polymorphs
  84. Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization
  85. Intraperitoneal injection of microencapsulated Sertoli cells restores muscle morphology and performance in dystrophic mice
  86. β-cyclodextrin hinders PLGA plasticization during microparticle manufacturing
  87. Effects of intraperitoneal injection of microencapsulated Sertoli cells on chronic and presymptomatic dystrophic mice
  88. Drug delivery system innovation and Health Technology Assessment: Upgrading from Clinical to Technological Assessment
  89. Alginate beads as a carrier for omeprazole/SBA-15 inclusion compound: A step towards the development of personalized paediatric dosage forms
  90. Alginates in Pharmaceutics and Biomedicine: Is the Future so Bright?
  91. Powder, capsule and device: An imperative ménage à trois for respirable dry powders
  92. Long-term stability, functional competence, and safety of microencapsulated specific pathogen-free neonatal porcine Sertoli cells: a potential product for cell transplant therapy
  93. Silica nanoparticles assisted photodegradation of acridine orange in aqueous suspensions
  94. Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3‐dioxygenase1
  95. Evaluation of a LC–MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard
  96. Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its d,l-polylactide microparticle formulation
  97. In vitro–in vivo correlation from lactide-co-glycolide polymeric dosage forms
  98. Microparticle-loaded neonatal porcine Sertoli cells for cell-based therapeutic and drug delivery system
  99. Chitosan films containing mesoporous SBA-15 supported silver nanoparticles for wound dressing
  100. Capreomycin inhalable powders prepared with an innovative spray-drying technique
  101. The Influence of Feedstock and Process Variables on the Encapsulation of Drug Suspensions by Spray‐Drying in Fast Drying Regime: The Case of Novel Antitubercular Drug–Palladium Complex Containing Polymeric Microparticles
  102. Development of Risperidone PLGA Microspheres
  103. IVIVC from Long Acting Olanzapine Microspheres
  104. Synthesis, characterization and in vitro extracellular and intracellular activity against Mycobacterium tuberculosis infection of new second-line antitubercular drug-palladium complexes
  105. Lipid nanoparticles for brain targeting II. Technological characterization
  106. Preparation, Characterization, and In Vivo Evaluation of Olanzapine Poly(D,L-lactide-co-glycolide) Microspheres
  107. Capreomycin supergenerics for pulmonary tuberculosis treatment: Preparation, in vitro, and in vivo characterization
  108. Colloidal nickel(0)-carboxymethyl cellulose particles: A biopolymer-inorganic catalyst for hydrogenation of nitro-aromatics and carbonyl compounds
  109. Development of a spray-drying method for the formulation of respirable microparticles containing ofloxacin–palladium complex
  110. Conformal polymer coatings for pancreatic islets transplantation
  111. Response to Comment on Blasi et al. (2011) “Lipid nanoparticles for brain targeting I. Formulation optimization”
  112. Synthesis of colloidal dispersions of NiAl, ZnAl, NiCr, ZnCr, NiFe, and MgFe hydrotalcite-like nanoparticles
  113. The real value of novel particulate carriers for sunscreen formulation
  114. Lipid nanoparticles for brain targeting I. Formulation optimization
  115. Solid Lipid Nanoparticles to Improve Brain Drug Delivery
  116. Development of a scalable procedure for fine calcium alginate particle preparation
  117. Formulation and Release Behavior of Doxycycline–Alginate Hydrogel Microparticles Embedded into Pluronic F127 Thermogels as a Potential New Vehicle for Doxycycline Intradermal Sustained Delivery
  118. Simple and scalable method for peptide inhalable powder production
  119. Bioactive Long-Term Release from Biodegradable Microspheres Preserves Implanted ALG-PLO-ALG Microcapsules from In Vivo Response to Purified Alginate
  120. Fighting tuberculosis: old drugs, new formulations
  121. Lipid Nanoparticles for Drug Delivery to the Brain: In Vivo Veritas
  122. Formulation studies of benzydamine mucoadhesive formulations for vaginal administration
  123. Novel composite microparticles for protein stabilization and delivery
  124. Eudragit® and hydrotalcite-like anionic clay composite system for diclofenac colonic delivery
  125. Influence of Compression Force on The Behavior of Mucoadhesive Buccal Tablets
  126. Physicochemical characterization and release mechanism of a novel prednisone biodegradable microsphere formulation
  127. Solid Lipid Nanoparticles for Targeted Brain Drug Delivery
  128. Improvement of dissolution rate of piroxicam by inclusion into MCM-41 mesoporous silicate
  129. Mucoadhesive bilayered tablets for buccal sustained release of flurbiprofen
  130. Modification of theophylline release with alginate gel formed in hard capsules
  131. Solid lipid nanoparticles for targeted brain drug delivery☆
  132. Ketoprofen poly(lactide-co-glycolide) physical interaction
  133. Preparation of large porous biodegradable microspheres by using a simple double-emulsion method for capreomycin sulfate pulmonary delivery
  134. Preparation and in vitro and in vivo characterization of composite microcapsules for cell encapsulation
  135. Delivering Drugs to the Central Nervous System: A Medicinal Chemistry or a Pharmaceutical Technology Issue?
  136. Development of liposomal capreomycin sulfate formulations: Effects of formulation variables on peptide encapsulation
  137. Evaluation and Optimization of the Conditions for an Improved Ferulic Acid Intercalation into a Synthetic Lamellar Anionic Clay
  138. Ketoprofen controlled release from composite microcapsules for cell encapsulation: Effect on post-transplant acute inflammation
  139. Long-term delivery of superoxide dismutase and catalase entrapped in poly(lactide-co-glycolide) microspheres: In vitro effects on isolated neonatal porcine pancreatic cell clusters
  140. Evaluation of Indomethacin Percutaneous Absorption from Nanostructured Lipid Carriers (NLC): In Vitro and In Vivo Studies
  141. Biodegradable microspheres as carriers for native superoxide dismutase and catalase delivery
  142. UV spectroscopy and reverse-phase HPLC as novel methods to determine Capreomycin of liposomal fomulations
  143. Development of mucoadhesive patches for buccal administration of ibuprofen
  144. Potential prodrugs of non-steroidal anti-inflammatory agents for targeted drug delivery to the CNS
  145. Leucinostatin-A loaded nanospheres: characterization and in vivo toxicity and efficacy evaluation
  146. Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease
  147. Unilamellar vesicles as potential capreomycin sulfate carriers: Preparation and physicochemical characterization
  148. Multifunctional microcapsules for pancreatic islet cell entrapment: design, preparation and in vitro characterization
  149. Preparation and characterization of poly(D,L-lactide-co-glycolide) microspheres for controlled release of human growth hormone