All Stories

  1. GP96 drives exacerbation of secondary bacterial pneumonia following influenza A virus infection

    Article • September 2020, Cold Spring Harbor Laboratory Press

    Dr Shigefumi Okamoto

  2. Impact of Gut Microbiome on Hypertensive Patients With Low-Salt Intake: Shika Study Results

    Article • Frontiers in Medicine, September 2020, Frontiers

    Dr Shigefumi Okamoto

  3. Stability of Skin Microbiome at Sacral Regions of Healthy Young Adults, Ambulatory Older Adults, and Bedridden Older Patients After 2 Years

    Article • Biological Research For Nursing, July 2020, SAGE Publications

    Dr Shigefumi Okamoto

  4. Skin Physiology and its Microbiome as Factors Associated with the Recurrence of Pressure Injuries

    Article • Biological Research For Nursing, July 2020, SAGE Publications

    Dr Shigefumi Okamoto

  5. Distinct Skin Microbiome and Skin Physiological Functions Between Bedridden Older Patients and Healthy People: A Single-Center Study in Japan

    Article • Frontiers in Medicine, April 2020, Frontiers

    Dr Shigefumi Okamoto

  6. Development of recurrent pressure ulcers, risk factors in older patients: a prospective observational study

    Article • Journal of Wound Care, April 2020, Mark Allen Group

    Dr Shigefumi Okamoto

  7. Pathogenicity Characterization of Prevalent-Type Streptococcus dysgalactiae subsp. equisimilis Strains

    Article • Frontiers in Microbiology, February 2020, Frontiers

    Dr Shigefumi Okamoto

  8. Feasibility of microbial sample collection on the skin from people in Yaoundé, Cameroon

    Article • Drug Discoveries & Therapeutics, December 2019, International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)

    Dr Shigefumi Okamoto

  9. Prevalence and genomic characterization of Group A Streptococcus dysgalactiae subsp. equisimilis isolated from patients with invasive infections in Toyama prefecture, Japan

    Article • Microbiology and Immunology, December 2019, Wiley

    Dr Shigefumi Okamoto

  10. Measuring the Antimicrobial Activity of Lauric Acid against Various Bacteria in Human Gut Microbiota Using a New Method

    Article • Cell Transplantation, October 2019, SAGE Publications

    Dr Shigefumi Okamoto

  11. Food bolus‐forming ability predicts incidence of aspiration pneumonia in nursing home older adults: A prospective observational study

    Article • Journal of Oral Rehabilitation, August 2019, Wiley

    Dr Shigefumi Okamoto

  12. Corrigendum: A Comparison of Techniques for Collecting Skin Microbiome Samples: Swabbing Versus Tape-Stripping

    Article • Frontiers in Microbiology, November 2018, Frontiers

    Dr Shigefumi Okamoto

  13. A Comparison of Techniques for Collecting Skin Microbiome Samples: Swabbing Versus Tape-Stripping

    Article • Frontiers in Microbiology, October 2018, Frontiers

    Dr Shigefumi Okamoto

  14. Pathogenic mechanisms of invasive group A Streptococcus infections by influenza virus-group A Streptococcus superinfection

    Article • Microbiology and Immunology, March 2018, Wiley

    Dr Shigefumi Okamoto

  15. Toll-like receptor 9 ligand D-type oligodeoxynucleotide D35 as a broad inhibitor for influenza A virus replication that is associated with suppression of neuraminidase activity

    Article • Antiviral Research, May 2016, Elsevier

    Dr Shigefumi Okamoto

  16. Dextran sulfate-resistant A/Puerto Rico/8/34 influenza virus is associated with the emergence of specific mutations in the neuraminidase glycoprotein

    Article • Antiviral Research, November 2014, Elsevier

    Dr Shigefumi Okamoto, Kenji Mizuguchi

  17. Neuraminidase gene homology contributes to the protective activity of influenza vaccines prepared from the influenza virus library

    Article • Journal of General Virology, July 2014, Society for General Microbiology

    Dr Shigefumi Okamoto

  18. An MDCK Cell Culture-Derived Formalin-Inactivated Influenza Virus Whole-Virion Vaccine from an Influenza Virus Library Confers Cross-Protective Immunity by Intranasal Administration in Mice

    Article • Clinical and Vaccine Immunology, May 2013, ASM Journals

    Dr Shigefumi Okamoto

  19. Study of Next Generation Influenza Vaccine Focused on ^|^ldquo;Cross-Protection by Mucosal Immunization^|^rdquo; and ^|^ldquo;Seed Virus Strains^|^rdquo;

    Article • YAKUGAKU ZASSHI, January 2013, Pharmaceutical Society of Japan

    Dr Shigefumi Okamoto

  20. Influenza virus neuraminidase contributes to the dextran sulfate-dependent suppressive replication of some influenza A virus strains

    Article • Antiviral Research, December 2012, Elsevier

    Dr Shigefumi Okamoto

  21. Comparison of the Cross-Reactive Anti-Influenza Neutralizing Activity of Polymeric and Monomeric IgA Monoclonal Antibodies

    Article • Viral Immunology, October 2012, Mary Ann Liebert Inc

    Dr Shigefumi Okamoto

  22. A community-based survey of varicella-zoster virus-specific immune responses in the elderly

    Article • Journal of Clinical Virology, September 2012, Elsevier

    Dr Shigefumi Okamoto

  23. Intranasal Immunization with a Formalin-Inactivated Human Influenza A Virus Whole-Virion Vaccine Alone and Intranasal Immunization with a Split-Virion Vaccine with Mucosal Adjuvants Show Similar Levels of Cross-Protection

    Article • Clinical and Vaccine Immunology, May 2012, ASM Journals

    Dr Shigefumi Okamoto

  24. Multiple Reversions of an IL2RG Mutation Restore T cell Function in an X-linked Severe Combined Immunodeficiency Patient

    Article • Journal of Clinical Immunology, March 2012, Springer Science + Business Media

    Dr Shigefumi Okamoto

  25. Poly-γ-Glutamic Acid Nanoparticles and Aluminum Adjuvant Used as an Adjuvant with a Single Dose of Japanese Encephalitis Virus-Like Particles Provide Effective Protection from Japanese Encephalitis Virus

    Article • Clinical and Vaccine Immunology, November 2011, ASM Journals

    Dr Shigefumi Okamoto

  26. Interleukin-1 Family Cytokines as Mucosal Vaccine Adjuvants for Induction of Protective Immunity against Influenza Virus

    Article • Journal of Virology, September 2010, ASM Journals

    Dr Shigefumi Okamoto

  27. Rapid and efficient introduction of a foreign gene into bacterial artificial chromosome-cloned varicella vaccine by Tn7-mediated site-specific transposition

    Article • Virology, June 2010, Elsevier

    Dr Shigefumi Okamoto

  28. Comparison of Varicella‐Zoster Virus–Specific Immunity of Patients with Diabetes Mellitus and Healthy Individuals

    Article • The Journal of Infectious Diseases, November 2009, Oxford University Press (OUP)

    Dr Shigefumi Okamoto

  29. Poly(γ-glutamic acid) nano-particles combined with mucosal influenza virus hemagglutinin vaccine protects against influenza virus infection in mice

    Article • Vaccine, September 2009, Elsevier

    Dr Shigefumi Okamoto

  30. A novel streptococcal leucine zipper protein (Lzp) binds to human immunoglobulins

    Article • Biochemical and Biophysical Research Communications, December 2008, Elsevier

    Dr Shigefumi Okamoto

  31. Measurement of Varicella‐Zoster Virus (VZV)–Specific Cell‐Mediated Immunity: Comparison between VZV Skin Test and Interferon‐γ Enzyme‐Linked Immunospot Assay

    Article • The Journal of Infectious Diseases, November 2008, Oxford University Press (OUP)

    Dr Shigefumi Okamoto

  32. Molecular and biological characterization of histidine triad protein in group A streptococci

    Article • Microbes and Infection, April 2008, Elsevier

    Dr Shigefumi Okamoto

  33. Streptococcal immunoglobulin-binding protein Sib35 exerts stimulatory and mitogenic effects toward mouse B lymphocytes

    Article • FEMS Microbiology Letters, April 2008, Oxford University Press (OUP)

    Dr Shigefumi Okamoto

  34. Single dose of inactivated Japanese encephalitis vaccine with poly(γ-glutamic acid) nanoparticles provides effective protection from Japanese encephalitis virus

    Article • Vaccine, January 2008, Elsevier

    Dr Shigefumi Okamoto

  35. Generation of a recombinant Oka varicella vaccine expressing mumps virus hemagglutinin-neuraminidase protein as a polyvalent live vaccine

    Article • Vaccine, December 2007, Elsevier

    Dr Shigefumi Okamoto

  36. Influenza hemagglutinin vaccine with poly(γ-glutamic acid) nanoparticles enhances the protection against influenza virus infection through both humoral and cell-mediated immunity

    Article • Vaccine, November 2007, Elsevier

    Dr Shigefumi Okamoto

  37. Inflammatory Immune Responses by Water-insoluble α-glucans

    Article • Journal of Dental Research, March 2007, SAGE Publications

    Dr Shigefumi Okamoto

  38. Protective Immunity against Streptococcus pyogenes Challenge in Mice after Immunization with Fibronectin‐Binding Protein

    Article • The Journal of Infectious Diseases, December 2005, Oxford University Press (OUP)

    Dr Shigefumi Okamoto

  39. Systemic immunization with streptococcal immunoglobulin-binding protein Sib35 induces protective immunity against group A Streptococcus challenge in mice

    Article • Vaccine, September 2005, Elsevier

    Dr Shigefumi Okamoto

  40. The Streptococcus pyogenes Capsule Is Required for Adhesion of Bacteria to Virus-Infected Alveolar Epithelial Cells and Lethal Bacterial-Viral Superinfection

    Article • Infection and Immunity, October 2004, ASM Journals

    Dr Shigefumi Okamoto

  41. Proapoptotic Effect of Proteolytic Activation of Matrix Metalloproteinases by Streptococcus pyogenes Thiol Proteinase (Streptococcus Pyrogenic Exotoxin B)

    Article • Infection and Immunity, August 2004, ASM Journals

    Dr Shigefumi Okamoto

  42. Vaccination with formalin-inactivated influenza vaccine protects mice against lethal influenza Streptococcus pyogenes superinfection

    Article • Vaccine, July 2004, Elsevier

    Dr Shigefumi Okamoto

  43. A model of invasive type of Streptococcus pyogenes infection after intranasal superinfection in influenza A virus-infected mice

    Article • International Congress Series, June 2004, Elsevier

    Dr Shigefumi Okamoto

  44. Influenza A Virus-Infected Hosts Boost an Invasive Type of Streptococcus pyogenes Infection in Mice

    Article • Journal of Virology, April 2003, ASM Journals

    Dr Shigefumi Okamoto

  45. Administration of Superantigens Protects Mice from Lethal Listeria monocytogenes Infection by Enhancing Cytotoxic T Cells

    Article • Infection and Immunity, November 2001, ASM Journals

    Dr Shigefumi Okamoto

  46. Extracellular Nicotinamide Adenine Dinucleotide Induces T Cell Apoptosis In Vivo and In Vitro

    Article • The Journal of Immunology, November 2001, The American Association of Immunologists

    Dr Shigefumi Okamoto

  47. Fas-Mediated Apoptosis Causes Elimination of Virus-Specific Cytotoxic T Cells in the Virus-Infected Liver

    Article • The Journal of Immunology, March 2001, The American Association of Immunologists

    Dr Shigefumi Okamoto

  48. NK Cells Cause Liver Injury and Facilitate the Induction of T Cell-Mediated Immunity to a Viral Liver Infection

    Article • The Journal of Immunology, June 2000, The American Association of Immunologists

    Dr Shigefumi Okamoto

  49. Fas- and tumor necrosis factor receptor 1-dependent but not perforin-dependent pathways cause injury in livers infected with an adenovirus construct in mice

    Article • Hepatology, March 2000, Wiley

    Dr Shigefumi Okamoto

  50. Superantigenicity of helper T‐cell mitogen (SPM‐2) isolated from culture supernatants of Streptococcus pyogenes

    Article • Immunology, July 1997, Wiley

    Dr Shigefumi Okamoto

  51. Molecular Cloning of a Functional Murine Arginine-Specific Mono-ADP-Ribosyltransferase and Its Expression in Lymphoid Cells

    Article • DNA and Cell Biology, February 1997, Mary Ann Liebert Inc

    Dr Shigefumi Okamoto

  52. Isolation of a new superantigen with potent mitogenic activity to murine T cells from Streptococcus pyogenes

    Article • FEMS Immunology & Medical Microbiology, September 1996, Oxford University Press (OUP)

    Dr Shigefumi Okamoto

  53. Elevated production of interleukin 6 by hepatic MNC correlates with ICAM-1 expression on the hepatic sinusoidal endothelial cells in autoimmune MRL/lpr mice

    Article • Immunology Letters, May 1993, Elsevier

    Dr Shigefumi Okamoto

  54. Water-insoluble α-glucans from Streptococcus sobrinus induce inflammatory immune responses

    Article • Springer Science + Business Media

    Dr Shigefumi Okamoto