All Stories

  1. In VitroandIn VivoCharacterization of the Novel Oxabicyclooctane-Linked Bacterial Topoisomerase Inhibitor AM-8722, a Selective, Potent Inhibitor of Bacterial DNA Gyrase
  2. C1–C2-linker substituted 1,5-naphthyridine analogues of oxabicyclooctane-linked NBTIs as broad-spectrum antibacterial agents (part 7)
  3. Circumambulatory Movement of Negative Charge (“Ring Walk”) during Gas-Phase Dissociation of 2,3,4-Trimethoxybenzoate Anion
  4. Isolation, structure elucidation and antibacterial activity of a new tetramic acid, ascosetin
  5. Oxabicyclooctane-Linked Novel Bacterial Topoisomerase Inhibitors as Broad Spectrum Antibacterial Agents
  6. Discovery and Development of Caspofungin (CANCIDAS): Concept to Clinic
  7. Isolation, Structure Elucidation, and Biological Activity of Altersolanol P Using Staphylococcus aureus Fitness Test Based Genome-Wide Screening
  8. Discovery and development of first in class antifungal caspofungin (CANCIDAS®)—A case study
  9. Determination of low levels of 2H‐labeling using high‐resolution mass spectrometry: Application in studies of lipid flux and beyond
  10. Design, Synthesis, and Evaluation of Prodrugs of Ertapenem
  11. Occurrence, distribution, dereplication and efficient discovery of thiazolyl peptides by sensitive-resistant pair screening
  12. Synthesis and antifungal evaluation of pentyloxyl-diphenylisoxazoloyl pneumocandins and echinocandins
  13. Coniothyrione: anatomy of a structure revision
  14. Structure–activity relationship of cytochrome bc1 reductase inhibitor broad spectrum antifungal ilicicolin H
  15. Isolation, Structure, and Biological Activity of Phaeofungin, a Cyclic Lipodepsipeptide from a Phaeosphaeria sp. Using the Genome-Wide Candida albicans Fitness Test
  16. Kibdelomycin A, a congener of kibdelomycin, derivatives and their antibacterial activities
  17. Direct mass spectrometric screening of antibiotics from bacterial surfaces using liquid extraction surface analysis
  18. Antifungal Spectrum, In Vivo Efficacy, and Structure–Activity Relationship of Ilicicolin H
  19. Pharmaceuticals: Natural Products and Natural Product Models
  20. Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain l-2-hydroxy acid oxidase
  21. Gordon M. Cragg, D.Phil., D.Sc. (h.c.): A Man for All Natural Products
  22. Isolation, Structure Elucidation, and Antibacterial Activity of Methiosetin, a Tetramic Acid from a Tropical Sooty Mold (Capnodium sp.)
  23. Chapter 12. Discovery and Development of Platensimycin and Platencin
  24. Natural Products in the 21st Century
  25. Biotransformation of antifungal ilicicolin H
  26. Potent and Selective Inhibitors of Long Chain l-2-Hydroxy Acid Oxidase Reduced Blood Pressure in DOCA Salt-Treated Rats
  27. Discovery and Development of Natural Product Inhibitors of HIV‐1 Integrase
  28. Screening strategies for discovery of antibacterial natural products
  29. Isolation, Structure, and Biological Activities of Fellutamides C and D from an Undescribed Metulocladosporiella (Chaetothyriales) Using the Genome-Wide Candida albicans Fitness Test
  30. Discovery of a potent and selective small molecule hGPR91 antagonist
  31. Confronting the Challenges of Natural Product-Based Antifungal Discovery
  32. Platensimycin and Platencin Congeners from Streptomyces platensis
  33. Triple Hyp→Pro replacement in integramide A, a peptaib inhibitor of HIV‐1 integrase: Effect on conformation and bioactivity
  34. ChemInform Abstract: Coelomycin, a Highly Substituted 2,6‐Dioxo‐pyrazine Fungal Metabolite Antibacterial Agent Discovered by Staphylococcus aureus Fitness Test Profiling
  35. Coelomycin, a highly substituted 2,6-dioxo-pyrazine fungal metabolite antibacterial agent discovered by Staphylococcus aureus fitness test profiling
  36. New antibiotic structures from fermentations
  37. ChemInform Abstract: Anthelmintic Constituents of Clonostachys candelabrum
  38. Configurational Assignment of D‐ and L‐Isovalines in Intact, Natural, and Synthetic Peptides by 2D‐NMR Spectroscopy
  39. Isolation, structure and biological activities of platencin A2–A4 from Streptomyces platensis
  40. Anthelmintic constituents of Clonostachys candelabrum
  41. ChemInform Abstract: Isolation, Enyzme‐Bound Structure and Antibacterial Activity of Platencin A1 from Streptomyces platensis.
  42. Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis
  43. Chemical Space and the Difference Between Natural Products and Synthetics
  44. ChemInform Abstract: Application of Combinatorial Biocatalysis for a Unique Ring Expansion of Dihydroxymethylzearalenone.
  45. ChemInform Abstract: Discovery and Antibacterial Activity of Glabramycin A—C from Neosartorya glabra by an Antisense Strategy.
  46. Isolation, enzyme-bound structure, and activity of platensimycin A1 from Streptomyces platensis
  47. Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis
  48. ChemInform Abstract: Discovery of Okilactomycin and Congeners from Streptomyces scabrisporus by Antisense Differential Sensitivity Assay Targeting Ribosomal Protein S4
  49. Application of combinatorial biocatalysis for a unique ring expansion of dihydroxymethylzearalenone
  50. Structure and Semisynthesis of Platensimide A, Produced by Streptomyces platensis
  51. Discovery and antibacterial activity of glabramycin A–C from Neosartorya glabra by an antisense strategy
  52. Thiazomycins, Thiazolyl Peptide Antibiotics from Amycolatopsis fastidiosa
  53. Synthesis and biological evaluation of platensimycin analogs
  54. Isolation, structure and antibacterial activity of pleosporone from a pleosporalean ascomycete discovered by using antisense strategy
  55. ChemInform Abstract: Isolation, Structure and Fatty Acid Synthesis Inhibitory Activities of Platensimycin B1—B3 from Streptomyces platensis.
  56. ChemInform Abstract: Isolation, Structure, and Antibacterial Activity of Thiazomycin A, a Potent Thiazolyl Peptide Antibiotic from Amycolatopsis fastidiosa.
  57. Isolation, structure and biological activity of phomafungin, a cyclic lipodepsipeptide from a widespread tropical Phoma sp.
  58. Discovery of okilactomycin and congeners from Streptomyces scabrisporus by antisense differential sensitivity assay targeting ribosomal protein S4
  59. Isolation, Structure, and Antibacterial Activities of Lucensimycins D−G, Discovered from Streptomyces lucensis MA7349 Using an Antisense Strategy
  60. Isolation, Structure Elucidation, and Biological Activity of Virgineone from Lachnum virgineum Using the Genome-Wide Candida albicans Fitness Test
  61. Complete Absolute Configuration of Integramide A, a Natural, 16‐mer Peptide Inhibitor of HIV‐1 Integrase, Elucidated by Total Synthesis
  62. Biosynthetic studies of Nocathiacin-I
  63. Isolation, structure, and antibacterial activity of thiazomycin A, a potent thiazolyl peptide antibiotic from Amycolatopsis fastidiosa
  64. Biosynthetic studies of platencin
  65. ChemInform Abstract: Structure and Semisynthesis of Platensimide A, Produced by Streptomyces platensis.
  66. ChemInform Abstract: Anthelmintic Macrolactams from Nonomuraea turkmeniaca MA7381.
  67. Isolation, Structure, and Antibacterial Activity of Philipimycin, A Thiazolyl Peptide Discovered from Actinoplanes philippinensis MA7347
  68. ChemInform Abstract: Structure of Homoplatensimide A: A Potential Key Biosynthetic Intermediate of Platensimycin Isolated from Streptomyces platensis.
  69. ChemInform Abstract: Discovery and Antibacterial Activity of Lucensimycin C from Streptomyces lucensis.
  70. Isolation, Structure, and Antibacterial Activity of Phaeosphenone from a Phaeosphaeria sp. Discovered by Antisense Strategy
  71. Pharmaceuticals: Natural Products and Natural Product Models
  72. Structure of homoplatensimide A: a potential key biosynthetic intermediate of platensimycin isolated from Streptomyces platensis
  73. Structure and Semisynthesis of Platensimide A, Produced by Streptomyces platensis
  74. Discovery and antibacterial activity of lucensimycin C from Streptomyces lucensis
  75. Special Issue in Honor of Professor George Robert Pettit
  76. Anthelmintic Macrolactams from Nonomuraea turkmeniaca MA7381
  77. ChemInform Abstract: Antibacterial Evaluations of Thiazomycin — A Potent Thiazolyl Peptide Antibiotic from Amycolatopsis fastidiosa.
  78. Isolation, structure and fatty acid synthesis inhibitory activities of platensimycin B1–B3 from Streptomyces platensis
  79. Flavones from Struthiola argentea with anthelmintic activity in vitro
  80. Noreupenifeldin, a Tropolone from an Unidentified Ascomycete
  81. Biosynthetic Studies of Platensimycin
  82. Chemistry of Platensimycin (I).
  83. Antibacterial Evaluations of Thiazomycin
  84. Isolation and Structure Elucidation of Thiazomycin
  85. Anthelmintic Macrolactams from Nonomuraea turkmeniaca MA7364
  86. Isolation, Structure, and Coccidiostat Activity of Coccidiostatin A
  87. Chemistry of platensimycin
  88. Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad‐Spectrum Antibiotic Activity
  89. Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad‐Spectrum Antibiotic Activity
  90. Discovery of Lucensimycins A (Ia) and B (Ib) from Streptomyces lucensis MA7349 Using an Antisense Strategy.
  91. Coniothyrione, a Chlorocyclopentandienylbenzopyrone as a Bacterial Protein Synthesis Inhibitor Discovered by Antisense Technology
  92. Anthelmintic Activity of Aporphine Alkaloids from Cissampelos capensis
  93. Scutiaquinones A and B, Perylenequinones from the Roots of Scutia myrtina with Anthelmintic Activity
  94. Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy [J. Am. Chem. Soc. 2006, 128, 11916−11920].
  95. Isolation and Insecticidal/Anthelmintic Activity of Xanthonol, a Novel Bis‐Xanthone, from a Non‐Sporulating Fungal Species.
  96. Discovery of Lucensimycins A and B from Streptomyces lucensis MA7349 Using an Antisense Strategy
  97. Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy
  98. In vivo evaluation of drug lead candidates by intravenous continuous infusion
  99. Gel-elongation assay for type II fatty acid synthesis
  100. A target-specific whole cell assay for antibacterial drug discovery
  101. Platensimycin is a selective FabF inhibitor with potent antibiotic properties
  102. Isolation and Insecticidal/Anthelmintic Activity of Xanthonol, a Novel Bis-xanthone, from a Non-sporulating Fungal species
  103. Isolation and Structures of Novel Fungal Metabolites as Chemokine Receptor (CCR2) Antagonists.
  104. Empirical antibacterial drug discovery—Foundation in natural products
  105. Highly Substituted Terphenyls as Inhibitors of Parasite cGMP-Dependent Protein Kinase Activity
  106. Discovery of Bacterial Fatty Acid Synthase Inhibitors from aPhomaSpecies as Antimicrobial Agents Using a New Antisense-Based Strategy
  107. New fungal metabolite geranylgeranyltransferase inhibitors with antifungal activity
  108. A new method for the synthesis of 1,4,5-oxadiazocines and its application in the structure modification of natural products
  109. Isolation and Structures of Novel Fungal Metabolites as Chemokine Receptor (CCR2) Antagonists
  110. Design, synthesis, and structure–activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis
  111. Steroidal and Triterpenoidal Fungal Metabolites as Ligands of Liver X Receptors
  112. Anthrabenzoxocinones from Streptomyces sp. as Liver X Receptor Ligands and Antibacterial Agents
  113. Diterpenoid, Steroid, and Triterpenoid Agonists of Liver X Receptors from Diversified Terrestrial Plants and Marine Sources
  114. Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters
  115. Tenellones A and B from a Diaporthe sp.:  Two Highly Substituted Benzophenone Inhibitors of Parasite cGMP-Dependent Protein Kinase Activity
  116. Guttiferone I, a New Prenylated Benzophenone from Garcinia humilis as a Liver X Receptor Ligand
  117. Identification of Diverse Microbial Metabolites as Potent Inhibitors of HIV-1 Tat Transactivation
  118. Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3
  119. Aspercyclide A—C, Three Novel Fungal Metabolites from Aspergillus sp. as Inhibitors of High‐Affinity IgE Receptor.
  120. Hinnuliquinone, a C2-symmetric dimeric non-peptide fungal metabolite inhibitor of HIV-1 protease
  121. Aspercyclide A–C, three novel fungal metabolites from Aspergillus sp. as inhibitors of high-affinity IgE receptor
  122. Nodulisporic Acids D−F:  Structure, Biological Activities, and Biogenetic Relationships
  123. Tremorgenic and Nontremorgenic 2,3‐Fused Indole Diterpenoids
  124. Isolation, Structure and HIV‐1 Integrase Inhibitory Activity of Exophillic Acid, a Novel Fungal Metabolite from Exophiala pisciphila.
  125. Citrafungins A and B, Two New Fungal Metabolite Inhibitors of GGTase I with Antifungal Activity.
  126. Isolation and Structure of Antagonists of Chemokine Receptor (CCR5)
  127. Isolation, Structure, Absolute Stereochemistry, and HIV-1 Integrase Inhibitory Activity of Integrasone, a Novel Fungal Polyketide
  128. Isolation, Structure, and HIV‐1 Integrase Inhibitory Activity of Xanthoviridicatin E and F, Two Novel Fungal Metabolites Produced by Penicillium chrysogenum.
  129. Rediocides B−E, Potent Insecticides from Trigonostemon reidioides
  130. Citrafungins A and B, Two New Fungal Metabolite Inhibitors of GGTase I with Antifungal Activity
  131. Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites
  132. Chemistry and Structure−Activity Relationship of HIV-1 Integrase Inhibitor Integracide B and Related Natural Products
  133. Isolation, Structure, and HIV‐1 Integrase Inhibitory Activity of Xanthoviridicatin E and F, Two Novel Fungal Metabolites Produced by Penicillium chrysogenum
  134. Four Novel Bis‐(naphtho‐γ‐pyrones) Isolated from Fusarium Species as Inhibitors of HIV‐1 Integrase.
  135. Integracides: tetracyclic triterpenoid inhibitors of HIV-1 integrase produced by Fusarium sp.
  136. Isolation, Structure, and HIV-1 Integrase Inhibitory Activity of Cytosporic Acid, a Fungal Metabolite Produced by a Cytospora sp.
  137. Nodulisporic Acid B, B1, and B2: A Series of 1′‐Deoxy‐nodulisporic Acids from Nodulisporium sp.
  138. Four novel bis-(naphtho-γ-pyrones) isolated from Fusarium species as inhibitors of HIV-1 integrase
  139. TREMORGENIC AND NONTREMORGENIC 2,3-FUSED INDOLE DITERPENOIDS
  140. Isolation, Structure and HIV-1 Integrase Inhibitory Activity of Exophillic Acid, a Novel Fungal Metabolite from Exophiala pisciphila
  141. Nodulisporic Acids C, C1, and C2:  A Series of D-Ring-Opened Nodulisporic Acids from the Fungus Nodulisporium sp.
  142. Nodulisporic acid B, B1, and B2: a series of 1′-deoxy-nodulisporic acids from Nodulisporium sp.
  143. ChemInform Abstract: Structure, Stereochemistry, and Biological Activity of Integramycin, a Novel Hexacyclic Natural Product Produced by Actinoplanes sp. that Inhibits HIV‐1 Integrase.
  144. Integramides A and B, Two Novel Non-Ribosomal Linear Peptides Containing Nine Cα-Methyl Amino Acids Produced by Fungal Fermentations That Are Inhibitors of HIV-1 Integrase
  145. ChemInform Abstract: Integrastatins: Structure and HIV‐1 Integrase Inhibitory Activities of Two Novel Racemic Tetracyclic Aromatic Heterocycles Produced by Two Fungal Species.
  146. Durhamycin A, a Potent Inhibitor of HIV Tat Transactivation
  147. ChemInform Abstract: Discovery, Structure and HIV‐1 Integrase Inhibitory Activities of Integracins, Novel Dimeric Alkyl Aromatics from Cytonaema sp.
  148. Integramides A and B, Two Novel Non-Ribosomal Linear Peptides Containing Nine Cα-Methyl Amino Acids Produced by Fungal Fermentations That Are Inhibitors of HIV-1 Integrase
  149. ChemInform Abstract: Discovery, Total Synthesis, HRV 3C‐Protease Inhibitory Activity, and Structure—Activity Relationships of 2‐Methoxystypandrone (VI) and Its Analogues.
  150. Structure, Stereochemistry, and Biological Activity of Integramycin, a Novel Hexacyclic Natural Product Produced by Actinoplanes sp. that Inhibits HIV-1 Integrase
  151. Integrastatins: structure and HIV-1 integrase inhibitory activities of two novel racemic tetracyclic aromatic heterocycles produced by two fungal species
  152. Discovery, structure and HIV-1 integrase inhibitory activities of integracins, novel dimeric alkyl aromatics from Cytonaema sp.
  153. ChemInform Abstract: Structure, Histone Deacetylase, and Antiprotozoal Activities of Apicidins B and C, Congeners of Apicidin with Proline and Valine Substitutions.
  154. Structure and Chemistry of Apicidins, a Class of Novel Cyclic Tetrapeptides without a Terminal α-Keto Epoxide as Inhibitors of Histone Deacetylase with Potent Antiprotozoal Activities
  155. Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure–activity relationships of 2-methoxystypandrone and its analogues
  156. ChemInform Abstract: Synthesis of Natural Flutimide and Analogous Fully Substituted Pyrazine‐2,6‐diones, Endonuclease Inhibitors of Influenza Virus.
  157. Structure, Histone Deacetylase, and Antiprotozoal Activities of Apicidins B and C, Congeners of Apicidin with Proline and Valine Substitutions
  158. Synthesis of Natural Flutimide and Analogous Fully Substituted Pyrazine-2,6-diones, Endonuclease Inhibitors of Influenza Virus
  159. The Complestatins as HIV-1 Integrase Inhibitors. Efficient Isolation, Structure Elucidation, and Inhibitory Activities of Isocomplestatin, Chloropeptin I, New Complestatins, A and B, and Acid-Hydrolysis Products of Chloropeptin I
  160. ChemInform Abstract: Diterpenoid Pyrones (I)—(III), Novel Blockers of the Voltage‐Gated Potassium Channel Kv1.3 from Fungal Fermentations.
  161. ChemInform Abstract: Candelalides A—C: Novel Diterpenoid Pyrones from Fermentations of Sesquicillium candelabrum as Blockers of the Voltage‐Gated Potassium Channel Kv1.3.
  162. Diterpenoid pyrones, novel blockers of the voltage-gated potassium channel Kv1.3 from fungal fermentations
  163. Candelalides A−C:  Novel Diterpenoid Pyrones from Fermentations of Sesquicillium candelabrum as Blockers of the Voltage-Gated Potassium Channel Kv1.3
  164. ChemInform Abstract: A New Mild PTSA‐Catalyzed Method for Sulfate Ester Hydrolysis and Acid‐Catalyzed Rearrangement of 12‐Acetyl‐dien‐11‐ol Tetracyclic Triterpenoids Involving an Angular Methyl Migration.
  165. ChemInform Abstract: Structure and Stereochemistry of Rediocide A, a Highly Modified Daphnane from Trigonostemon reidioides Exhibiting Potent Insecticidal Activity.
  166. A new mild PTSA-catalyzed method for sulfate ester hydrolysis and acid-catalyzed rearrangement of 12-acetyl-diene-11-ol tetracyclic triterpenoids involving an angular methyl migration
  167. ChemInform Abstract: Chemical and Enzymatic Modifications of Integric Acid and HIV‐1 Integrase Inhibitory Activity.
  168. Structure and Stereochemistry of Rediocide A, A Highly Modified Daphnane from Trigonostemon reidioides Exhibiting Potent Insecticidal Activity
  169. Efficient syntheses, human and yeast farnesyl-protein transferase inhibitory activities of chaetomellic acids and analogues
  170. ChemInform Abstract: Structure and Absolute Stereochemistry of HIV‐1 Integrase Inhibitor Integric Acid. A Novel Eremophilane Sesquiterpenoid Produced by a Xylaria sp.
  171. Chemical and enzymatic modifications of integric acid and HIV-1 integrase inhibitory activity
  172. Farnesyl-Protein Transferase: A New Paradigm for Cancer Chemotherapy, Advances in Discovery and Development of Natural Product Inhibitors
  173. Structure and absolute stereochemistry of HIV-1 integrase inhibitor integric acid. A novel eremophilane sesquiterpenoid produced by a Xylaria sp.
  174. ChemInform Abstract: Coprophilin: An Anticoccidial Agent Produced by a Dung Inhabiting Fungus.
  175. Coprophilin: An anticoccidial agent produced by a dung inhabiting fungus
  176. Selective and controlled hydrolysis of chloropeptin I. HIV-1 integrase activity of fragments
  177. Clavaric Acid:  A Triterpenoid Inhibitor of Farnesyl-Protein Transferase from Clavariadelphus truncatus
  178. Kampanols: novel ras farnesyl-protein transferase inhibitors from Stachybotrys kampalensis
  179. Equisetin and a novel opposite stereochemical homolog phomasetin, two fungal metabolites as inhibitors of HIV-1 integrase
  180. Complestatin to chloropeptin I via a quantitative acid catalyzed rearrangement. Absolute stereochemical determination of complestatin.
  181. Practical Syntheses of 13-O-[(2-Methoxyethoxy)methyl]-22,23-dihydroavermectin B1 Aglycon [Dimedectin Isopropanol, MK-324] and 13-epi-O-(Methoxymethyl)-22,23-Dihydroavermectin B1 Aglycon [L-694,554], Flea Activ...
  182. Fusidienol A:  A Novel Ras Farnesyl-Protein Transferase Inhibitor from Phoma sp.
  183. Nodulisporic Acid A, a Novel and Potent Insecticide from a Nodulisporium Sp. Isolation, Structure Determination, and Chemical Transformations
  184. SPORANDOL: A NOVEL ANTIPARASITIC BINAPHTHALENE FROM CHRYSOSPORIUM MERIDARIUM
  185. Oreganic Acid, a Potent Inhibitor of Ras Farnesyl-Protein Transferase
  186. Section Review Oncologic, Endocrine & Metabolic: Farnesyl-protein transferase inhibitors in early development
  187. Apicidins: Novel cyclic tetrapeptides as coccidiostats and antimalarial agents from Fusarium pallidoroseum
  188. Oreganic acid: a potent novel inhibitor of ras farnesyl-protein transferase from an endophytic fungus
  189. Ophiobolin M and analogues, noncompetitive inhibitors of ivermectin binding with nematocidal activity
  190. Dolastatins 24: synthesis of (–)-dolastatin 10. X-Ray molecular structure of N,N-dimethylvalyl-valyl-dolaisoleuine tert-butyl ester
  191. Chemistry and Biology of Cylindrols:  Novel Inhibitors of Ras Farnesyl-Protein Transferase from Cylindrocarpon lucidum
  192. New fungal metabolites as potential antihypercholesterolemics and anticancer agents
  193. Structure, Chemistry, and Biology of Actinoplanic Acids: Potent Inhibitors of Ras Farnesyl-Protein Transferase
  194. Using similarity searches over databases of estimated 13C NMR spectra for structure identification of natural product compounds
  195. Oteromycin: A Novel Antagonist of Endothelin Receptor
  196. Antineoplastic Agents. 291. Isolation and Synthesis of Combretastatins A-4, A-5, and A-6. [Erratum to document cited in CA122:290568]
  197. Cylindrol A: A novel inhibitor of Ras farnesyl-protein transferase from Cylindrocarpon lucidum
  198. Barceloneic Acid A, a New Farnesyl-Protein Transferase Inhibitor from a Phoma Species
  199. Antineoplastic Agents. 291. Isolation and Synthesis of Combretastatins A-4, A-5, and A-6
  200. A carotane sesquiterpene as a potent modulator of the Maxi-K channel from Arthrinium phaesospermum
  201. Total synthesis of flutimide, a novel endonuclease inhibitor of influenza virus
  202. Isolation and structure of flutimide, a novel endonuclease inhibitor of influenza virus
  203. Actinoplanic Acid A: A Macrocyclic Polycarboxylic Acid Which Is a Potent Inhibitor of Ras Farnesyl-Protein Transferase
  204. The Dolastatins. 17. Synthesis of Dolaproine and Related Diastereoisomers
  205. Preussomerins and Deoxypreussomerins: Novel Inhibitors of Ras Farnesyl-Protein Transferase
  206. Fusidienol: A novel inhibitor of Ras farnesyl-protein transferase from Fusidium griseum
  207. The Dolastatins. 22. Synthesis Of Boc-Dolaproinyl Dolaphenine and Four Related Chiral Isomers
  208. The Dolastatins. 19. Synthesis of Dolaisoleuine
  209. The Dolastatins 20. A Convenient Synthetic Route to Dolastatin 15
  210. The Dolastatins 16. Synthesis of Dolaphenine
  211. Maxikdiol: a novel dihydroxyisoprimane as an agonist of Maxi-K channels
  212. Zaragozic Acids D and D2: Potent Inhibitors of Squalene Synthase and of Ras Farnesyl-Protein Transferase
  213. Synthesis of chaetomellic acid A: A potent inhibitor of Ras farnesyl-protein transferase
  214. Isolation and structure of chaetomellic acids A and B from Chaetomella acutiseta: farnesyl pyrophosphate mimic inhibitors of ras farnesyl-protein transferase
  215. Inversion of the sterically constrained C13-hydroxyl of 22,23-dihydroavermectin B1 aglycone
  216. Oxidation of spiroketones with DDQ - synthesis of tropone derivatives and DDHQ diesters
  217. Variculanol: structure and absolute stereochemistry of a novel 5/12/5 tricyclic sesterterpenoid from Aspergillus variecolor
  218. Structure of stereochemistry of thysanone: a novel human rhinovirus 3C-protease inhibitor from Thysanophora penicilloides
  219. Antineoplastic agents. 220. Synthesis of natural (-)-dolastatin 15
  220. Structure and conformation of ophiobolin K and 6- epiophiobolin K from Aspergillus ustus as a nematocidal agent.
  221. Chiral modifications of dolastatin 10: the potent cytostatic peptide (19aR)-isodolastatin 10
  222. Antineoplastic Agents, 195. Isolation and Structure of Aceratioside from Aceratium megalospermum
  223. Antineoplastic agents. 206. Structure of the cytostatic macrocyclic lactone combretastatin D-2
  224. Antineoplastic Agents, 162. Zephyranthes candida
  225. Antineoplastic agents. 166. Isolation, structure, and synthesis of combretastatin C-1
  226. Antineoplastic agents. Part 189. The absolute configuration and synthesis of natural (-)-dolastatin 10
  227. Antineoplastic agents. 160. Isolation and structure of combretastatin D-1: a cell growth inhibitory macrocyclic lactone from Combretum caffrum
  228. Isolation, Structure, Synthesis, and Antimitotic Properties of Combretastatins B-3 and B-4 from Combretum caffrum
  229. Cell growth inhibitory dihydrophenanthrene and phenanthrene constituents of the african tree Combretum caffrum
  230. Isolation, structure, and synthesis of combretastatin A-2, A-3, and B-2
  231. Synthesis of (±)-Isocombretastatins A-C
  232. Antineoplastic Agents, 122. Constituents of Combretum caffrum
  233. On the role of leucine in terpenoid metabolism
  234. Isolation, Structure, and Synthesis of Combretastatins A-1 and B-1, Potent New Inhibitors of Microtubule Assembly, Derived from Combretum caffrum
  235. Antineoplastic Agents, 120. Pancratium littorale
  236. Antineoplastic agents. 113. Synthesis of natural (-)-combretastatin
  237. The role of leucine in isoprenoid metabolism. Incorporation of [3-13C]leucine and of [2-3H,4-14C]-β,β-dimethylacrylic acid into phytosterols by tissue cultures of Andrographis paniculata
  238. Synthesis of (2RS)‐[3‐13C]‐ and (2RS)‐[3‐14C] leucine
  239. Angelicoidenol, a bicyclic monoterpene from the seeds of Pleurospermum angelicoides
  240. The role of leucine in terpenoid metabolism. Incorporation of [2-13C]- and [3-13C]-leucines into sesquiterpenoids by tissue cultures of Andrographis paniculata
  241. Saponins From the Seeds of Costus speciosus
  242. Furostanol saponins from Paris polyphylla: Structures of polyphyllin G and H
  243. Costusoside-I and costusoside-J, two new furostanol saponins from the seeds of Costus speciosus
  244. Spirostanol saponins from Paris polyphylla, structures of polyphyllin C, D, E and F
  245. 1-vinylmenth-4(8)-ene, a terpenoid hydrocarbon from Mentha citrata
  246. Biodiversity, chemical diversity and drug discovery