All Stories

  1. Synthesis of novel d-α-galactopyranosyl-l-seryl/l-threonyl-l-alanyl-l-alanine as useful precursors of new glycopeptide antibiotics with computational calculations studies

    Article • Carbohydrate Research, April 2022, Elsevier

    Dr. Shaymaa Emam Kassab

  2. Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity

    Article • Bioorganic Chemistry, February 2022, Elsevier

    Dr. Shaymaa Emam Kassab, Professor Bahaa Elgendy

  3. Febuxostat-based amides and some derived heterocycles targeting xanthine oxidase and COX inhibition. Synthesis, in vitro and in vivo biological evaluation, molecular modeling and in silico ADMET studies

    Article • Bioorganic Chemistry, August 2021, Elsevier

    Dr. Shaymaa Emam Kassab

  4. Structural Basis of Selective Human Indoleamine‐2,3‐dioxygenase 1 (hIDO1) Inhibition

    Article • ChemMedChem, July 2021, Wiley

    Dr. Shaymaa Emam Kassab

  5. Indomethacin from Anti-Inflammatory to Anticancer Agent

    Article • March 2019, IntechOpen

    Dr. Shaymaa Emam Kassab

  6. Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2019, Taylor & Francis

    Dr Nesreen Nabil Omar, Dr. Shaymaa Emam Kassab

  7. Design, synthesis, biological evaluation and docking studies of new 3-(4,5-dihydro-1 H -pyrazol/isoxazol-5-yl)-2-phenyl-1 H -indole derivatives as potent antioxidants and 15-lipoxygenase inhibitors

    Article • European Journal of Medicinal Chemistry, February 2018, Elsevier

    Mostafa El-Miligy, Dr. Shaymaa Emam Kassab

  8. Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities

    Article • European Journal of Medicinal Chemistry, December 2017, Elsevier

    Dr. Shaymaa Emam Kassab

  9. A Promising Anti-Cancer and Anti-Oxidant Agents Based on the Pyrrole and Fused Pyrrole: Synthesis, Docking Studies and Biological Evaluation

    Article • Anti-Cancer Agents in Medicinal Chemistry, April 2015, Bentham Science Publishers

    Dr samar S fatahala Radwan , Dr. Shaymaa Emam Kassab

  10. Base-catalyzed one-step synthesis of 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines

    Article • Tetrahedron Letters, February 2015, Elsevier

    Dr. Shaymaa Emam Kassab

  11. Design, synthesis, 3D pharmacophore, QSAR, and docking studies of carboxylic acid derivatives as Histone Deacetylase inhibitors and cytotoxic agents

    Article • Bioorganic Chemistry, December 2014, Elsevier

    Dr. Shaymaa Emam Kassab

  12. Synthesis of New 9-glycosyl-4,9-dihydropyrano [3,4-b]indole-1(3H)-ones as Antibacterial Agents

    Article • Nucleosides Nucleotides & Nucleic Acids, November 2011, Taylor & Francis

    Dr. Shaymaa Emam Kassab

  13. Synthesis of 1H-Indole-2,3-Dione-3-Thiosemicarbazone Ribonucleosides as Antibacterial Agents

    Article • Nucleosides Nucleotides & Nucleic Acids, January 2010, Taylor & Francis

    Dr. Shaymaa Emam Kassab