Contact

All Stories

  1. Engineered mRNA–ribosome fusions for facile biosynthesis of selenoproteins

    Article • Proceedings of the National Academy of Sciences, March 2024, Proceedings of the National Academy of Sciences

    Sergey Melnikov

  2. Split aminoacyl-tRNA synthetases for proximity-induced stop codon suppression

    Article • Proceedings of the National Academy of Sciences, February 2023, Proceedings of the National Academy of Sciences

    Sergey Melnikov

  3. Bacterial translation machinery for deliberate mistranslation of the genetic code

    Article • Proceedings of the National Academy of Sciences, August 2021, Proceedings of the National Academy of Sciences

    Sergey Melnikov

  4. Selective cysteine-to-selenocysteine changes in a [NiFe]-hydrogenase confirm a special position for catalysis and oxygen tolerance

    Article • Proceedings of the National Academy of Sciences, March 2021, Proceedings of the National Academy of Sciences

    Sergey Melnikov

  5. Exploiting evolutionary trade-offs for posttreatment management of drug-resistant populations

    Article • Proceedings of the National Academy of Sciences, July 2020, Proceedings of the National Academy of Sciences

    Sergey Melnikov

  6. Archaeal Ribosomal Proteins Possess Nuclear Localization Signal-Type Motifs: Implications for the Origin of the Cell Nucleus

    Article • Molecular Biology and Evolution, September 2019, Oxford University Press (OUP)

    Sergey Melnikov

  7. Aminoacyl-tRNA Synthetases and tRNAs for an Expanded Genetic Code: What Makes them Orthogonal?

    Article • International Journal of Molecular Sciences, April 2019, MDPI AG

    Sergey Melnikov

  8. Engineered Aminoacyl-tRNA Synthetases with Improved Selectivity toward Noncanonical Amino Acids

    Article • ACS Chemical Biology, April 2019, American Chemical Society (ACS)

    Sergey Melnikov

  9. Muller’s Ratchet and Ribosome Degeneration in the Obligate Intracellular Parasites Microsporidia

    Article • International Journal of Molecular Sciences, December 2018, MDPI AG

    Sergey Melnikov

  10. Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site

    Article • Nucleic Acids Research, December 2018, Oxford University Press (OUP)

    Sergey Melnikov

  11. Muller’s Ratchet and Ribosome Degeneration in the Obligate Intracellular Parasites Microsporidia

    Article • November 2018, MDPI AG

    Sergey Melnikov

  12. Loss of protein synthesis quality control in host-restricted organisms

    Article • Proceedings of the National Academy of Sciences, November 2018, Proceedings of the National Academy of Sciences

    Sergey Melnikov

  13. Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance

    Article • Journal of Molecular Biology, August 2018, Elsevier

    Sergey Melnikov

  14. Error-prone protein synthesis in parasites with the smallest eukaryotic genome

    Article • Proceedings of the National Academy of Sciences, June 2018, Proceedings of the National Academy of Sciences

    Sergey Melnikov

  15. Challenges of site-specific selenocysteine incorporation into proteins by Escherichia coli

    Article • RNA Biology, March 2018, Taylor & Francis

    Sergey Melnikov

  16. Revising the Structural Diversity of Ribosomal Proteins Across the Three Domains of Life

    Article • Molecular Biology and Evolution, February 2018, Oxford University Press (OUP)

    Sergey Melnikov

  17. RNA-Dependent Cysteine Biosynthesis in Bacteria and Archaea

    Article • mBio, May 2017, ASM Journals

    Sergey Melnikov, Dr Nikos C Kyrpides

  18. Molecular insights into protein synthesis with proline residues

    Article • EMBO Reports, November 2016, EMBO

    Sergey Melnikov

  19. Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome

    Article • Journal of Molecular Biology, September 2016, Elsevier

    Sergey Melnikov

  20. Insights into the origin of the nuclear localization signals in conserved ribosomal proteins

    Article • Nature Communications, June 2015, Springer Science + Business Media

    Sergey Melnikov

  21. Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

    Article • Nature Structural & Molecular Biology, March 2015, Springer Science + Business Media

    Sergey Melnikov

  22. Crystal structure of the 80S yeast ribosome

    Article • Current Opinion in Structural Biology, December 2012, Elsevier

    Sergey Melnikov

  23. One core, two shells: bacterial and eukaryotic ribosomes

    Article • Nature Structural & Molecular Biology, June 2012, Springer Science + Business Media

    Sergey Melnikov

  24. The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

    Article • Science, November 2011, American Association for the Advancement of Science

    Sergey Melnikov

  25. Effect of prothymosin α and its mutants on the activity of the p53 tumor suppressor

    Article • Molecular Biology, August 2008, Pleiades Publishing Ltd

    Sergey Melnikov

  26. Interaction with Keap1 does not lead to ubiquitination and degradation of prothymosin α

    Article • Molecular Biology, October 2007, Pleiades Publishing Ltd

    Sergey Melnikov

  27. New Functions of a Well-Known Protein: Prothymosin α Is Involved in Protecting Cells from Apoptosis and Oxidative Stress

    Article • Molecular Biology, September 2005, Springer Science + Business Media

    Sergey Melnikov

  28. Nuclear Oncoprotein Prothymosin α Is a Partner of Keap1: Implications for Expression of Oxidative Stress-Protecting Genes

    Article • Molecular and Cellular Biology, February 2005, ASM Journals

    Sergey Melnikov