All Stories

  1. Discovery of p-Trifluoromethylbenzohydrazide Derivatives as Potent Antiviral Agents against Monkeypox Virus
  2. Structure-based targeting of the lipid A-modifying enzyme PmrC to contrast colistin resistance in Acinetobacter baumannii
  3. Structural studies of KCTD1 and its disease-causing mutant P20S provide insights into the protein function and misfunction
  4. A rationally designed antigen elicits protective antibodies against multiple nosocomial Gram-positive pathogens
  5. HtpG—A Major Virulence Factor and a Promising Vaccine Antigen against Mycobacterium tuberculosis
  6. Klebsiella phage KP34gp57 capsular depolymerase structure and function: from a serendipitous finding to the design of active mini-enzymes against K. pneumoniae
  7. Virulence Factors in Mycobacterium tuberculosis Infection: Structural and Functional Studies
  8. Structural Basis of PE_PGRS Polymorphism, a Tool for Functional Modulation
  9. Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation
  10. A Structural View at Vaccine Development against M. tuberculosis
  11. Molecular Immunology in Bacterial Vaccine Discovery
  12. Understanding Molecular Actors of SARS-CoV-2 Virulence to Tackle COVID-19 Outbreak
  13. Conformational stability of ageritin, a metal binding ribotoxin-like protein of fungal origin
  14. PGRS domain structures: Doomed to sail the mycomembrane
  15. Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis
  16. Resveratrol Reverts Tolerance and Restores Susceptibility to Chlorhexidine and Benzalkonium in Gram-Negative Bacteria, Gram-Positive Bacteria and Yeasts
  17. Structural and Binding Properties of the Active Cell Wall Hydrolase RipA from M. tuberculosis, a Promising Biosensing Molecule for Early Warning Bacterial Detection
  18. Structure-Based Development of SARS-CoV-2 Spike Interactors
  19. Structural and Biochemical Characterization of Endo-β-1,4-glucanase from Dictyoglomus thermophilum, a Hyperthermostable and Halotolerant Cellulase
  20. Inhibition of AdeB, AceI, and AmvA Efflux Pumps Restores Chlorhexidine and Benzalkonium Susceptibility in Acinetobacter baumannii ATCC 19606
  21. Protein with negative surface charge distribution, Bnr1, shows characteristics of a DNA‐mimic protein and may be involved in the adaptation of Burkholderia cenocepacia
  22. A global analysis of conservative and non-conservative mutations in SARS-CoV-2 detected in the first year of the COVID-19 world-wide diffusion
  23. AlphaFold-Predicted Structures of KCTD Proteins Unravel Previously Undetected Relationships among the Members of the Family
  24. A structure-based approach for the development of a bicyclic peptide acting as a miniaturized anti-CD55 antibody
  25. Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation
  26. PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction betweenM. tuberculosisand host cells
  27. Thinking Outside the Bug: Targeting Outer Membrane Proteins for Burkholderia Vaccines
  28. PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response
  29. Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins
  30. Structural features of HtpGMtb and HtpG-ESAT6Mtb vaccine antigens against tuberculosis: Molecular determinants of antigenic synergy and cytotoxicity modulation
  31. PE_PGRS proteins ofMycobacterium tuberculosis: A specialized molecular task force at the forefront of host–pathogen interaction
  32. Structural and Functional Studies of a Klebsiella Phage Capsule Depolymerase Tailspike: Mechanistic Insights into Capsular Degradation
  33. A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping
  34. The non-swapped monomeric structure of the arginine-binding protein from Thermotoga maritima
  35. Molecular Biomarkers of Disease for Diagnosis and Drug Development
  36. Binding and enzymatic properties of Ageritin, a fungal ribotoxin with novel zinc-dependent function
  37. Structural and dynamic studies provide insights into specificity and allosteric regulation of ribonuclease as, a key enzyme in mycobacterial virulence
  38. Streptococcal Collagen-like Protein 1 Binds Wound Fibronectin: Implications in Pathogen Targeting
  39. Molecular Biomarkers of Disease for Diagnosis and Drug Development
  40. The Cell Wall Hydrolytic NlpC/P60 Endopeptidases in Mycobacterial Cytokinesis: A Structural Perspective
  41. Adaptation of the group A Streptococcus adhesin Scl1 to bind fibronectin type III repeats within wound‐associated extracellular matrix: implications for cancer therapy
  42. Structural and enzymatic properties of Ageritin, a novel metal-dependent ribotoxin-like protein with antitumor activity
  43. Domain communication in Thermotoga maritima Arginine Binding Protein unraveled through protein dissection
  44. Phage-Borne Depolymerases Decrease Klebsiella pneumoniae Resistance to Innate Defense Mechanisms
  45. Collagen degradation in tuberculosis pathogenesis: the biochemical consequences of hosting an undesired guest
  46. Domain swapping dissection in Thermotoga maritima arginine binding protein: How structural flexibility may compensate destabilization
  47. PASTA sequence composition is a predictive tool for protein class identification
  48. Surface-exposed loops and an acidic patch in the Scl1 protein of group A Streptococcus enable Scl1 binding to wound-associated fibronectin
  49. The novel thermostable cellulose-degrading enzyme DtCel5H from Dictyoglomus thermophilum: crystallization and X-ray crystallographic analysis
  50. A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics
  51. Chemistry of Peptidoglycan in Mycobacterium tuberculosis Life Cycle: An off-the-wall Balance of Synthesis and Degradation
  52. Structural Versatility of Hepatitis C Virus Proteins: Implications for the Design of Novel Anti-HCV Intervention Strategies
  53. Molecular Players in Tuberculosis Drug Development: Another Break in the Cell Wall
  54. Defense Against Pathogens: Structural Insights into the Mechanism of Chitin Induced Activation of Innate Immunity
  55. Editorial: Molecular Scenarios Behind Infectious Diseases
  56. PASTA in Penicillin Binding Proteins and Serine/Threonine Kinases: A Recipe of Structural, Dynamic and Binding Properties
  57. Collagen‐like proteins of pathogenic streptococci
  58. Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy
  59. a key bactrial protein that can serve as a vaccine
  60. Use of Hydrolytic Enzymes for Algal Biomass Treatment
  61. Unique Footprint in the scl1.3 Locus Affects Adhesion and Biofilm Formation of the Invasive M3-Type Group A Streptococcus
  62. Structural and dynamic features of PASTA domains with different functional roles
  63. Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis
  64. Identification of an OmpW homologue in Burkholderia pseudomallei, a protective vaccine antigen against melioidosis
  65. The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains
  66. MAbs against cyclic Epitope I of HCV E2
  67. NMR Structure and Dynamics of the Resuscitation Promoting Factor RpfC Catalytic Domain
  68. A product of RpfB and RipA joint enzymatic action promotes the resuscitation of dormant mycobacteria
  69. Differential thermodynamic behaviours of the extra-cellular regions of two Ser/Thr PrkC kinases revealed by calorimetric studies
  70. Exit from Mycobacterial Dormancy: A Structural Perspective
  71. Antimicrobial Peptides as an Opportunity Against Bacterial Diseases
  72. Structure and Function of RNase AS: A Novel Virulence Factor From Mycobacterium tuberculosis
  73. Editorial (Thematic Issue: Molecular Determinants of Bacterial Diseases)
  74. Chemistry of Lipid A: At the Heart of Innate Immunity
  75. Mutational and structural study of RipA, a key enzyme inMycobacterium tuberculosiscell division: evidence for theL-to-Dinversion of configuration of the catalytic cysteine
  76. A Loose Domain Swapping Organization Confers a Remarkable Stability to the Dimeric Structure of the Arginine Binding Protein from Thermotoga maritima
  77. Structure and Function of RNase AS, a Polyadenylate-Specific Exoribonuclease Affecting Mycobacterial Virulence In Vivo
  78. Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein fromMycobacterium tuberculosis
  79. The Crystal Structure of the Streptococcal Collagen-like Protein 2 Globular Domain from Invasive M3-type Group A Streptococcus Shows Significant Similarity to Immunomodulatory HIV Protein gp41
  80. Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization
  81. Conformational Modifications of gB from Herpes Simplex Virus Type 1 Analyzed by Synthetic Peptides
  82. Crystallization and preliminary X-ray crystallographic analysis of the variable domain of Scl2.3, a streptococcal collagen-like protein from invasive M3-typeStreptococcus pyogenes
  83. Structures of free and inhibited forms of theL,D-transpeptidase LdtMt1fromMycobacterium tuberculosis
  84. Carbohydrate Recognition by RpfB from Mycobacterium tuberculosis Unveiled by Crystallographic and Molecular Dynamics Analyses
  85. Expression, purification, crystallization and preliminary X-ray crystallographic analysis of theL,D-transpeptidase LdtMt1fromMycobacterium tuberculosis
  86. Molecular determinants of inactivation of the resuscitation promoting factor B fromMycobacterium tuberculosis
  87. Interplay between Peptide Bond Geometrical Parameters in Nonglobular Structural Contexts
  88. Polyproline and Triple Helix Motifs in Host-Pathogen Recognition
  89. Bacterial Cell Division Regulation by Ser/Thr Kinases: A Structural Perspective
  90. Editorial (Hot Topic: Learning from Pathogens: Exploiting Host-Pathogen Liaison for Therapeutic Development)
  91. Editorial (Hot Topic: Cell Processes in Bacterial Diseases)
  92. Structural and Dynamic Properties of Incomplete Immunoglobulin-like Fold Domains
  93. Structural and enzymatic properties of an in vivo proteolytic form of PD-S2, type 1 ribosome-inactivating protein from seeds of Phytolacca dioica L.
  94. Enhanced Crystallizability by Protein Engineering Approaches: A General Overview
  95. Mapping key interactions in the dimerization process of HBHA fromMycobacterium tuberculosis, insights into bacterial agglutination
  96. Chemical Basis of Peptidoglycan Discrimination by PrkC, a Key Kinase Involved in Bacterial Resuscitation from Dormancy
  97. Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms ofThermotoga maritimaarginine-binding protein
  98. Heparin-binding hemagglutinin HBHA from Mycobacterium tuberculosis affects actin polymerisation
  99. Role of Hydration in Collagen Recognition by Bacterial Adhesins
  100. X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus
  101. Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB fromMycobacterium tuberculosis
  102. Dynamical properties of cold shock protein A from Mycobacterium tuberculosis
  103. Expression, Purification, Crystallization and Preliminary X-Ray Crystallographic Analysis of the Peptidoglycan Binding Region of the Ser/Thr Kinase PrkC from Staphylococcus aureus
  104. Structure and Functional Regulation of RipA, a Mycobacterial Enzyme Essential for Daughter Cell Separation
  105. Nobel Prize in Chemistry 2009: When Biology Turns into Chemistry
  106. Elongation Factors EFIA and EF-Tu: Their Role in Translation and Beyond
  107. Dimerisation and structural integrity of Heparin Binding Hemagglutinin A from Mycobacterium tuberculosis : Implications for bacterial agglutination
  108. The role of the glycan moiety on the structure–function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves
  109. Type 1 Ribosome-Inactivating Proteins from the Ombú Tree (Phytolacca dioica L.)
  110. Expression, Purification, Crystallization and Preliminary X-Ray Crystallographic Analysis of the Resuscitation Promoting Factor Interacting Protein RipA from M. tuberculosis
  111. Crystal structure of PD-L1, a ribosome inactivating protein fromPhytolacca dioicaL. Leaves with the property to induce DNA cleavage
  112. Comment onMicrofibrillar structure of type I collagenin situby Orgelet al.(2006),Proc. Natl Acad. Sci. USA,103, 9001–9005
  113. Crystal structure of the collagen triple helix model [(Pro-Pro-Gly)10]3
  114. Molecular dynamics studies of the P pilus rod subunit PapA
  115. Ribosome's mode of function: myths, facts and recent results
  116. Role of side chains in collagen triple helix stabilization and partner recognition
  117. Phase behavior and crystallogenesis under counter-diffusion conditions of the collagen-model peptide (Pro–Pro–Gly)10
  118. Crystal Structure of the Resuscitation-Promoting Factor ΔDUFRpfB from M. tuberculosis
  119. Conformational states and association mechanism of Yersinia pestis Caf1 subunits
  120. Role of hydration in collagen triple helix stabilization
  121. Contribution of dipole-dipole interactions to the stability of the collagen triple helix
  122. Evidence for an Elongated Dimeric Structure of Heparin-Binding Hemagglutinin from Mycobacterium tuberculosis
  123. Atomic resolution (1.1 Å) structure of the ribosome-inactivating protein PD-L4 fromPhytolacca dioicaL. leaves
  124. Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor fromMycobacterium tuberculosis
  125. A Molecular Dynamics Study of Pilus Subunits: Insights into Pilus Biogenesis
  126. Crystallization and Preliminary X-Ray Diffraction Analysis of PD-L1, a Highly Glycosylated Ribosome Inactivating Protein with DNase Activity
  127. Fate of prions in soil: Interaction of a recombinant ovine prion protein with synthetic humic-like mineral complexes
  128. Crystallization and Preliminary X-Ray Diffraction Analysis of PD-L4, a Ribosome Inactivating Protein from Phytolacca dioica L. leaves
  129. 23S rRNA 2058A→G Alteration Mediates Ketolide Resistance in Combination with Deletion in L22
  130. Polyproline Helices in Protein Structures: A Statistical Survey
  131. The effect of the osmolyte trimethylamine N-oxide on the stability of the prion protein at low pH
  132. Limited tendency of α-helical residues to form disulfide bridges: a structural explanation
  133. A crevice adjoining the ribosome tunnel: Hints for cotranslational folding
  134. Functional aspects of ribosomal architecture: symmetry, chirality and regulation
  135. Imino Acids and Collagen Triple Helix Stability:  Characterization of Collagen-like Polypeptides Containing Hyp-Hyp-Gly Sequence Repeats
  136. Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism
  137. Characterization of collagen-like heterotrimers: Implications for triple-helix stability
  138. Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease
  139. Structural Insight into the Antibiotic Action of Telithromycin against Resistant Mutants
  140. Ribosomal crystallography: Peptide bond formation and its inhibition
  141. Structural Insight into the Antibiotic Action of Telithromycin against Resistant Mutants
  142. On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes. Delivered on 20 October 2002 at the 28th FEBS Meeting in Istanbul
  143. Structural insight into the role of the ribosomal tunnel in cellular regulation
  144. Structural Basis of the Ribosomal Machinery for Peptide Bond Formation, Translocation, and Nascent Chain Progression
  145. Crystallization of the collagen-like polypeptide (PPG)10 aboard the International Space Station. 2. Comparison of crystal quality by X-ray diffraction
  146. Recent Progress on Collagen Triple Helix Structure, Stability and Assembly
  147. Atomic resolution structures of ribonuclease A at six pH values
  148. Video observation of protein crystal growth in the advanced protein crystallization facility aboard the space shuttle mission STS-95
  149. Atomic resolution structure of a mutant of the spectrin SH3 domain
  150. Structural bases of collagen stabilization induced by proline hydroxylation
  151. Effects of microgravity on the crystal quality of a collagen-like polypeptide
  152. Protein titration in the crystal state
  153. Crystallization of multiple forms of bovine seminal ribonuclease in the liganded and unliganded state
  154. Thermodynamic Analysis of α-spectrin SH3 and Two of Its Circular Permutants with Different Loop Lengths:  Discerning the Reasons for Rapid Folding in Proteins,
  155. X-ray crystallographic determination of a collagen-like peptide with the repeating sequence (Pro-Pro-Gly)
  156. Protein Crystal Growth in the Advanced Protein Crystallization Facility on the LMS Mission: a Comparison of Sulfolobus solfataricus Alcohol Dehydrogenase Crystals Grown on the Ground and in Microgravity