All Stories

  1. Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain

    Article • Biomedical Spectroscopy and Imaging, July 2019, IOS Press

    Professor Risto A Kauppinen

  2. Observation of angular dependence of T1 in the human white matter at 3T

    Article • Biomedical Spectroscopy and Imaging, January 2019, IOS Press

    Professor Risto A Kauppinen

  3. T2 Relaxometry and Diffusion Tensor Indices of the Hippocampus and Entorhinal Cortex Improve Sensitivity and Specificity of MRI to Detect Amnestic Mild Cognitive Impairment and Alzheimer's Disease Dementia

    Article • Journal of Magnetic Resonance Imaging, September 2018, Wiley

    Professor Risto A Kauppinen

  4. Cerebral White Matter Maturation Patterns in Preterm Infants: An MRI T2 Relaxation Anisotropy and Diffusion Tensor Imaging Study

    Article • Journal of Neuroimaging, December 2017, Wiley

    Professor Risto A Kauppinen

  5. Stroke onset time determination using MRI relaxation times without non-ischaemic reference in a rat stroke model

    Article • Biomedical Spectroscopy and Imaging, May 2017, IOS Press

    Professor Risto A Kauppinen

  6. Computed tomography-based acute stroke lesion timing and patient stratification

    Article • Annals of Neurology, April 2017, Wiley

    Professor Risto A Kauppinen

  7. Stroke onset time estimation from multispectral quantitative magnetic resonance imaging in a rat model of focal permanent cerebral ischemia

    Article • International Journal of Stroke, July 2016, SAGE Publications

    Professor Risto A Kauppinen

  8. A spatiotemporal theory for MRI T2 relaxation time and apparent diffusion coefficient in the brain during acute ischaemia: Application and validation in a rat acute stroke model

    Article • Journal of Cerebral Blood Flow & Metabolism, October 2015, SAGE Publications

    Professor Risto A Kauppinen

  9. Multiparametric magnetic resonance imaging of acute experimental brain ischaemia

    Article • Progress in Nuclear Magnetic Resonance Spectroscopy, July 2014, Elsevier

    Professor Risto A Kauppinen

  10. Clinical Proton MR Spectroscopy in Central Nervous System Disorders

    Article • Radiology, March 2014, Radiological Society of North America (RSNA)

    Professor Risto A Kauppinen, Professor Martin O Leach

  11. Blood oxygenation level dependent, blood volume, and blood flow responses to carbogen and hypoxic hypoxia in 9L rat gliomas as measured by MRI

    Article • Journal of Magnetic Resonance Imaging, January 2014, Wiley

    Professor Risto A Kauppinen

  12. Relaxation Along a Fictitious Field (RAFF) and Z-spectroscopy using Alternating-Phase Irradiation (ZAPI) in Permanent Focal Cerebral Ischemia in Rat

    Article • PLoS ONE, July 2013, PLOS

    Professor Risto A Kauppinen

  13. Blood oxygenation level dependent, blood volume, and blood flow responses to carbogen and hypoxic hypoxia in 9L rat gliomas as measured by MRI

    Article • Journal of Magnetic Resonance Imaging, April 2013, Wiley

    Professor Risto A Kauppinen

  14. Magnetic resonance spectroscopy metabolite profiles predict survival in paediatric brain tumours

    Article • European Journal of Cancer, January 2013, Elsevier

    Professor Risto A Kauppinen

  15. Increased unsaturation of lipids in cytoplasmic lipid droplets in DAOY cancer cells in response to cisplatin treatment

    Article • Metabolomics, December 2012, Springer Science + Business Media

    Professor Risto A Kauppinen

  16. Simultaneous BOLD fMRI and local field potential measurements during kainic acid–induced seizures

    Article • Epilepsia, June 2012, Wiley

    Professor Risto A Kauppinen

  17. The size of cytoplasmic lipid droplets varies between tumour cell lines of the nervous system: a 1H NMR spectroscopy study

    Article • Magnetic Resonance Materials in Physics Biology and Medicine, April 2012, Springer Science + Business Media

    Professor Risto A Kauppinen

  18. Lipid biomarkers of glioma cell growth arrest and cell death detected by 1H magic angle spinning MRS

    Article • NMR in Biomedicine, March 2012, Wiley

    Professor Risto A Kauppinen

  19. Gray matter nulled and vascular space occupancy dependent fMRI response to visual stimulation during hypoxic hypoxia

    Article • NeuroImage, February 2012, Elsevier

    Professor Risto A Kauppinen

  20. Magnetic Resonance Imaging Reveals Slow-down of Global Cerebral Oxygen Metabolism in Multiple Sclerosis

    Article • Journal of Cerebral Blood Flow & Metabolism, January 2012, SAGE Publications

    Professor Risto A Kauppinen

  21. Dynamic changes in oxygenation of intracranial tumor and contralateral brain during tumor growth and carbogen breathing: A multisite EPR oximetry with implantable resonators

    Article • Journal of Magnetic Resonance, January 2012, Elsevier

    Professor Risto A Kauppinen

  22. The lipid composition of isolated cytoplasmic lipid droplets from a human cancer cell line, BE(2)M17

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Professor Risto A Kauppinen

  23. Using magnetic resonance imaging and spectroscopy in cancer diagnostics and monitoring

    Article • Cancer Biology & Therapy, October 2011, Taylor & Francis

    Professor Risto A Kauppinen

  24. 1H magnetic resonance spectroscopy metabolites as biomarkers for cell cycle arrest and cell death in rat glioma cells

    Article • The International Journal of Biochemistry & Cell Biology, July 2011, Elsevier

    Professor Risto A Kauppinen

  25. In Vitro Metabonomic Study Detects Increases in UDP-GlcNAc and UDP-GalNAc, as Early Phase Markers of Cisplatin Treatment Response in Brain Tumor Cells

    Article • Journal of Proteome Research, June 2011, American Chemical Society (ACS)

    Professor Risto A Kauppinen

  26. Image contrast in fluorescence and magnetic resonance images for glioblastoma detection

    Article • February 2011, SPIE

    Professor Risto A Kauppinen

  27. Protoporphyrin IX fluorescence contrast in invasive glioblastomas is linearly correlated with Gd enhanced magnetic resonance image contrast but has higher diagnostic accuracy

    Article • Journal of Biomedical Optics, January 2011, SPIE

    Professor Risto A Kauppinen

  28. Z-spectroscopy with Alternating-Phase Irradiation

    Article • Journal of Magnetic Resonance, December 2010, Elsevier

    Professor Risto A Kauppinen

  29. Gd‐Labeled Microparticles in MRI: In vivo Imaging of Microparticles After Intraperitoneal Injection

    Article • Small, November 2010, Wiley

    Professor Risto A Kauppinen

  30. Effect of Hyperoxygenation on Tissue pO2 and Its Effect on Radiotherapeutic Efficacy of Orthotopic F98 Gliomas

    Article • International Journal of Radiation Oncology*Biology*Physics, November 2010, Elsevier

    Professor Risto A Kauppinen

  31. A comparison between simulated and experimental basis sets for assessing short‐TE in vivo1H MRS data at 1.5 T

    Article • NMR in Biomedicine, October 2010, Wiley

    Professor Risto A Kauppinen

  32. A constrained least‐squares approach to the automated quantitation of in vivo 1H magnetic resonance spectroscopy data

    Article • Magnetic Resonance in Medicine, September 2010, Wiley

    Professor Risto A Kauppinen

  33. Tuftsin derivatives of FITC, Tb–DOTA or Gd–DOTA as potential macrophage‐specific imaging biomarkers

    Article • Contrast Media & Molecular Imaging, July 2010, Wiley

    Professor Risto A Kauppinen

  34. Correlating Tissue Outcome with Quantitative Multiparametric MRI of Acute Cerebral Ischemia in Rats

    Article • Journal of Cerebral Blood Flow & Metabolism, November 2009, SAGE Publications

    Professor Risto A Kauppinen

  35. Monitoring of gliomas in vivo by diffusion MRI and 1H MRS during gene therapy‐induced apoptosis: interrelationships between water diffusion and mobile lipids

    Article • NMR in Biomedicine, November 2008, Wiley

    Professor Risto A Kauppinen

  36. Quantitative Assessment of Water Pools by T1p and T2p MRI in Acute Cerebral Ischemia of the Rat

    Article • Journal of Cerebral Blood Flow & Metabolism, October 2008, SAGE Publications

    Professor Risto A Kauppinen

  37. A Functional Magnetic Resonance Imaging Technique Based on Nulling Extravascular Gray Matter Signal

    Article • Journal of Cerebral Blood Flow & Metabolism, August 2008, SAGE Publications

    Professor Risto A Kauppinen

  38. The BOLD response and vascular reactivity during visual stimulation in the presence of hypoxic hypoxia

    Article • NeuroImage, June 2008, Elsevier

    Professor Risto A Kauppinen

  39. Interleukin‐1 exacerbates focal cerebral ischemia and reduces ischemic brain temperature in the rat

    Article • Magnetic Resonance in Medicine, April 2008, Wiley

    Professor Risto A Kauppinen

  40. 31P magnetic resonance spectroscopy study of the human visual cortex during stimulation in mild hypoxic hypoxia

    Article • Experimental Brain Research, February 2008, Springer Science + Business Media

    Professor Risto A Kauppinen

  41. Synthesis and Spectroscopic Properties of a Prototype Single Molecule Dual Imaging Agent Comprising a Heterobimetallic Rhenium−Gadolinium Complex

    Article • Journal of the American Chemical Society, January 2008, American Chemical Society (ACS)

    Professor Risto A Kauppinen, Dr Louise S Natrajan

  42. Proliferating Resident Microglia after Focal Cerebral Ischaemia in Mice

    Article • Journal of Cerebral Blood Flow & Metabolism, December 2007, SAGE Publications

    Professor Risto A Kauppinen

  43. Assessment of human brain temperature by 1H MRS during visual stimulation and hypercapnia

    Article • NMR in Biomedicine, September 2007, Wiley

    Professor Risto A Kauppinen

  44. Oxygenation and hematocrit dependence of transverse relaxation rates of blood at 3T

    Article • Magnetic Resonance in Medicine, August 2007, Wiley

    Professor Risto A Kauppinen

  45. Low Spin-Lock Field T1 Relaxation in the Rotating Frame as a Sensitive MR Imaging Marker for Gene Therapy Treatment Response in Rat Glioma1

    Article • Radiology, June 2007, Radiological Society of North America (RSNA)

    Professor Risto A Kauppinen, Dr Seppo Yla-Herttuala

  46. Proton transfer ratio, lactate, and intracellular pH in acute cerebral ischemia

    Article • Magnetic Resonance in Medicine, March 2007, Wiley

    Professor Risto A Kauppinen

  47. A metabolomics perspective of human brain tumours

    Article • FEBS Journal, February 2007, Wiley

    Professor Risto A Kauppinen

  48. Effects of radiation damping on Z-spectra

    Article • Journal of Magnetic Resonance, December 2006, Elsevier

    Professor Risto A Kauppinen

  49. Tumour Metabolomics in Animal Models of Human Cancer

    Article • Journal of Proteome Research, November 2006, American Chemical Society (ACS)

    Professor Risto A Kauppinen

  50. Determination of regional brain temperature using proton magnetic resonance spectroscopy to assess brain–body temperature differences in healthy human subjects

    Article • Magnetic Resonance in Medicine, November 2006, Wiley

    Professor Risto A Kauppinen

  51. Effects of mild hypoxic hypoxia on poststimulus undershoot of blood-oxygenation-level-dependent fMRI signal in the human visual cortex

    Article • Magnetic Resonance Imaging, October 2006, Elsevier

    Professor Risto A Kauppinen

  52. Effects of oxygen saturation on BOLD and arterial spin labelling perfusion fMRI signals studied in a motor activation task

    Article • NeuroImage, March 2006, Elsevier

    Professor Risto A Kauppinen

  53. Manganese-enhanced magnetic resonance imaging of mossy fiber plasticity in vivo

    Article • NeuroImage, March 2006, Elsevier

    Professor Risto A Kauppinen

  54. Status Epilepticus in 12‐day‐old Rats Leads to Temporal Lobe Neurodegeneration and Volume Reduction: A Histologic and MRI Study

    Article • Epilepsia, March 2006, Wiley

    Professor Risto A Kauppinen

  55. Heterogeneous Oxygen Extraction in the Visual Cortex during Activation in Mild Hypoxic Hypoxia Revealed by Quantitative Functional Magnetic Resonance Imaging

    Article • Journal of Cerebral Blood Flow & Metabolism, February 2006, SAGE Publications

    Professor Risto A Kauppinen

  56. High-Resolution Magic Angle Spinning 1H NMR Spectroscopy and Reverse Transcription-PCR Analysis of Apoptosis in a Rat Glioma

    Article • Analytical Chemistry, January 2006, American Chemical Society (ACS)

    Professor Risto A Kauppinen

  57. A luminescent probe containing a tuftsin targeting vector coupled to a terbium complex

    Article • Chemical Communications, January 2006, Royal Society of Chemistry

    Professor Risto A Kauppinen

  58. Long-term protective effect of atorvastatin in permanent focal cerebral ischemia

    Article • Brain Research, August 2005, Elsevier

    Professor Risto A Kauppinen

  59. Quantitative T1ρ and adiabatic Carr–Purcell T2 magnetic resonance imaging of human occipital lobe at 4 T

    Article • Magnetic Resonance in Medicine, June 2005, Wiley

    Professor Risto A Kauppinen

  60. High‐resolution magic‐angle‐spinning 1H NMR spectroscopy reveals different responses in choline‐containing metabolites upon gene therapy‐induced programmed cell death in rat brain glioma

    Article • NMR in Biomedicine, May 2005, Wiley

    Professor Risto A Kauppinen

  61. Minocycline Protects against Permanent Cerebral Ischemia in Wild Type but Not in Matrix Metalloprotease-9-Deficient Mice

    Article • Journal of Cerebral Blood Flow & Metabolism, April 2005, SAGE Publications

    Professor Risto A Kauppinen

  62. Dynamic dephasing changes in developing ischemic cerebral infarction in rats studied by Carr–Purcell T2 magnetic resonance imaging

    Article • Magnetic Resonance in Medicine, March 2005, Wiley

    Professor Risto A Kauppinen

  63. Exchange‐influenced T2ρ contrast in human brain images measured with adiabatic radio frequency pulses

    Article • Magnetic Resonance in Medicine, March 2005, Wiley

    Professor Risto A Kauppinen

  64. Progression of Brain Damage after Status Epilepticus and Its Association with Epileptogenesis: A Quantitative MRI Study in a Rat Model of Temporal Lobe Epilepsy

    Article • Epilepsia, August 2004, Wiley

    Professor Risto A Kauppinen

  65. Acute cerebral ischemia in rats studied by Carr‐Purcell spin‐echo magnetic resonance imaging: Assessment of blood oxygenation level‐dependent and tissue effects on the transverse relaxation

    Article • Magnetic Resonance in Medicine, May 2004, Wiley

    Professor Risto A Kauppinen

  66. Assessment of cerebral hemodynamics and oxygen extraction using dynamic susceptibility contrast and spin echo blood oxygenation level-dependent magnetic resonance imaging: applications to carotid stenosis patients

    Article • NeuroImage, May 2004, Elsevier

    Professor Risto A Kauppinen

  67. Quantitative t1ρ NMR spectroscopy of rat cerebral metabolites in vivo: Effects of global ischemia

    Article • Magnetic Resonance in Medicine, April 2004, Wiley

    Professor Risto A Kauppinen

  68. Water diffusion in a rat glioma during ganciclovir‐thymidine kinase gene therapy‐induced programmed cell death in vivo: Correlation with cell density

    Article • Journal of Magnetic Resonance Imaging, March 2004, Wiley

    Professor Risto A Kauppinen, Dr Seppo Yla-Herttuala

  69. B0 dependence of the on‐resonance longitudinal relaxation time in the rotating frame (T1ρ) in protein phantoms and rat brain in vivo

    Article • Magnetic Resonance in Medicine, December 2003, Wiley

    Professor Risto A Kauppinen

  70. Comparison of BOLD fMRI and MEG characteristics to vibrotactile stimulation

    Article • NeuroImage, August 2003, Elsevier

    Professor Risto A Kauppinen

  71. Effects of hematocrit and oxygen saturation level on blood spin‐lattice relaxation

    Article • Magnetic Resonance in Medicine, March 2003, Wiley

    Professor Risto A Kauppinen

  72. Quantification of Human Brain Metabolites from In Vivo 1H NMR Magnitude Spectra Using Self-Organising Maps

    Article • January 2003, Springer Science + Business Media

    Professor Risto A Kauppinen

  73. On‐ and off‐resonance T1ρ MRI in acute cerebral ischemia of the rat

    Article • Magnetic Resonance in Medicine, December 2002, Wiley

    Professor Risto A Kauppinen

  74. Adenovirus-mediated herpes simplex virus thymidine kinase gene therapy in BT4C rat glioma model

    Article • Cancer Gene Therapy, October 2002, Springer Science + Business Media

    Professor Risto A Kauppinen, Dr Seppo Yla-Herttuala

  75. The combination of HSV-tk and endostatin gene therapy eradicates orthotopic human renal cell carcinomas in nude mice

    Article • Cancer Gene Therapy, October 2002, Springer Science + Business Media

    Professor Risto A Kauppinen, Dr Seppo Yla-Herttuala

  76. Blood NMR relaxation in the rotating frame: mechanistic implications

    Article • Archives of Biochemistry and Biophysics, September 2002, Elsevier

    Professor Risto A Kauppinen

  77. Effects of intracellular pH, blood, and tissue oxygen tension on T1ρ relaxation in rat brain

    Article • Magnetic Resonance in Medicine, August 2002, Wiley

    Professor Risto A Kauppinen

  78. Quantitative T1ρ and Magnetization Transfer Magnetic Resonance Imaging of Acute Cerebral Ischemia in the Rat

    Article • Journal of Cerebral Blood Flow & Metabolism, May 2002, SAGE Publications

    Professor Risto A Kauppinen

  79. Early gene therapy–induced apoptotic response in BT4C gliomas by magnetic resonance relaxation contrast T1 in the rotating frame

    Article • Cancer Gene Therapy, April 2002, Springer Science + Business Media

    Professor Risto A Kauppinen, Dr Seppo Yla-Herttuala

  80. Expression of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor-2 (KDR/Flk-1) in Ischemic Skeletal Muscle and Its Regeneration

    Article • American Journal Of Pathology, April 2002, Elsevier

    Professor Risto A Kauppinen, PhD Mikko P Turunen, Dr Seppo Yla-Herttuala

  81. Quantitative Assessment of the Balance between Oxygen Delivery and Consumption in the Rat Brain after Transient Ischemia with T2-BOLD Magnetic Resonance Imaging

    Article • Journal of Cerebral Blood Flow & Metabolism, March 2002, SAGE Publications

    Professor Risto A Kauppinen

  82. Monitoring cytotoxic tumour treatment response by diffusion magnetic resonance imaging and proton spectroscopy

    Article • NMR in Biomedicine, January 2002, Wiley

    Professor Risto A Kauppinen

  83. Quantification of Human Brain Metabolites from in Vivo1H NMR Magnitude Spectra Using Automated Artificial Neural Network Analysis

    Article • Journal of Magnetic Resonance, January 2002, Elsevier

    Professor Risto A Kauppinen

  84. Application of Self-Organising Maps in Automated Chemical Shift Correction of In Vivo 1H MR Spectra

    Article • January 2002, Springer Science + Business Media

    Professor Risto A Kauppinen

  85. Progression of neuronal damage after status epilepticus and during spontaneous seizures in a rat model of temporal lobe epilepsy

    Article • January 2002, Elsevier

    Professor Risto A Kauppinen

  86. Proton Exchange as a Relaxation Mechanism for T1 in the Rotating Frame in Native and Immobilized Protein Solutions

    Article • Biochemical and Biophysical Research Communications, December 2001, Elsevier

    Professor Risto A Kauppinen

  87. Assessment of brain tissue viability in acute ischemic stroke by BOLD MRI

    Article • NMR in Biomedicine, November 2001, Wiley

    Professor Risto A Kauppinen

  88. Assessment of brain tissue viability in acute ischemic stroke by BOLD MRI

    Article • NMR in Biomedicine, November 2001, Wiley

    Professor Risto A Kauppinen

  89. Ex vivo MR microimaging of neuronal damage after kainate‐induced status epilepticus in rat: Correlation with quantitative histology

    Article • Magnetic Resonance in Medicine, November 2001, Wiley

    Professor Risto A Kauppinen

  90. Ex vivo MR microimaging of neuronal damage after kainate‐induced status epilepticus in rat: Correlation with quantitative histology

    Article • Magnetic Resonance in Medicine, October 2001, Wiley

    Professor Risto A Kauppinen

  91. Cerebral T1ρ relaxation time increases immediately upon global ischemia in the rat independently of blood glucose and anoxic depolarization

    Article • Magnetic Resonance in Medicine, August 2001, Wiley

    Professor Risto A Kauppinen

  92. Inverse T2 contrast at 1.5 Tesla between gray matter and white matter in the occipital lobe of normal adult human brain

    Article • Magnetic Resonance in Medicine, July 2001, Wiley

    Professor Risto A Kauppinen

  93. Measurement of tissue oxygen extraction ratios from venous blood T2: Increased precision and validation of principle

    Article • Magnetic Resonance in Medicine, July 2001, Wiley

    Professor Risto A Kauppinen

  94. HSV-tk gene therapy for human renal cell carcinoma in nude mice

    Article • Cancer Gene Therapy, July 2001, Springer Science + Business Media

    Professor Risto A Kauppinen, Dr Seppo Yla-Herttuala

  95. Use of spin echo T2 BOLD in assessment of cerebral misery perfusion at 1.5 T

    Article • Magnetic Resonance Materials in Physics Biology and Medicine, February 2001, Springer Science + Business Media

    Professor Risto A Kauppinen

  96. Interrelations of T1 and diffusion of water in acute cerebral ischemia of the rat

    Article • Magnetic Resonance in Medicine, December 2000, Wiley

    Professor Risto A Kauppinen

  97. MAO-B Inhibition by a Single Dose of l-Deprenyl or Lazabemide Does Not Prevent Neuronal Damage Following Focal Cerebral Ischaemia in Rats

    Article • Pharmacology & Toxicology, November 2000, Wiley

    Professor Risto A Kauppinen

  98. MAO‐B Inhibition by a Single Dose of l‐Deprenyl or Lazabemide Does Not Prevent Neuronal Damage Following Focal Cerebral Ischaemia in Rats

    Article • Pharmacology & Toxicology, November 2000, Wiley

    Professor Risto A Kauppinen

  99. Early Detection of Irreversible Cerebral Ischemia in the Rat Using Dispersion of the Magnetic Resonance Imaging Relaxation Time, T1ρ

    Article • Journal of Cerebral Blood Flow & Metabolism, October 2000, SAGE Publications

    Professor Risto A Kauppinen

  100. 1H NMR visible lipids in the life and death of cells

    Article • Trends in Biochemical Sciences, August 2000, Elsevier

    Professor Risto A Kauppinen

  101. Graded Reduction of Cerebral Blood Flow in Rat as Detected by the Nuclear Magnetic Resonance Relaxation Time T2: A Theoretical and Experimental Approach

    Article • Journal of Cerebral Blood Flow & Metabolism, February 2000, SAGE Publications

    Professor Risto A Kauppinen

  102. Reduction in Water and Metabolite Apparent Diffusion Coefficients During Energy Failure Involves Cation-Dependent Mechanisms. A Proton Nuclear Magnetic Resonance Study of Rat Cortical Brain Slices

    Article • Journal of Cerebral Blood Flow & Metabolism, February 2000, SAGE Publications

    Professor Risto A Kauppinen

  103. Interrelations ofT1 and diffusion of water in acute cerebral ischemia of the rat

    Article • Magnetic Resonance in Medicine, January 2000, Wiley

    Professor Risto A Kauppinen

  104. Determination of Oxygen Extraction Ratios by Magnetic Resonance Imaging

    Article • Journal of Cerebral Blood Flow & Metabolism, December 1999, SAGE Publications

    Professor Risto A Kauppinen

  105. 1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: Implications for the in vivo detection of apoptosis

    Article • Nature Reports Stem Cells, November 1999, Springer Science + Business Media

    Professor Risto A Kauppinen, Dr Seppo Yla-Herttuala

  106. Venous blood effects in spin-echo fMRI of human brain

    Article • Magnetic Resonance in Medicine, October 1999, Wiley

    Professor Risto A Kauppinen

  107. Quantitative magnetic resonance imaging assessment of cerebral ischemia in rat using on-resonance T1 in the rotating frame

    Article • Magnetic Resonance in Medicine, August 1999, Wiley

    Professor Risto A Kauppinen

  108. Quantitative magnetic resonance imaging assessment of cerebral ischemia in rat using on‐resonance T1 in the rotating frame

    Article • Magnetic Resonance in Medicine, August 1999, Wiley

    Professor Risto A Kauppinen

  109. In Vivo Determination of Absolute Cerebral Blood Volume Using Hemoglobin as a Natural Contrast Agent: An MRI Study Using Altered Arterial Carbon Dioxide Tension

    Article • Journal of Cerebral Blood Flow & Metabolism, July 1999, SAGE Publications

    Professor Risto A Kauppinen

  110. Diagnostic assessment of brain tumours and non-neoplastic brain disorders in vivo using proton nuclear magnetic resonance spectroscopy and artificial neural networks

    Article • Journal of Cancer Research and Clinical Oncology, May 1999, Springer Science + Business Media

    Professor Risto A Kauppinen

  111. Neuroprotection by the α2-adrenoceptor agonist, dexmedetomidine, in rat focal cerebral ischemia

    Article • European Journal of Pharmacology, May 1999, Elsevier

    Professor Risto A Kauppinen

  112. Enhanced ornithine decarboxylase activity is associated with attenuated rate of damage evolution and reduction of infarct volume in transient middle cerebral artery occlusion in the rat1Published on the World Wide Web on 17 March 1999.1

    Article • Brain Research, May 1999, Elsevier

    Professor Risto A Kauppinen

  113. Monitoring the CNS Pathology in Aspartylglucosaminuria Mice

    Article • Journal of Neuropathology & Experimental Neurology, December 1998, Oxford University Press (OUP)

    Professor Risto A Kauppinen

  114. Automated Quantification of Human Brain Metabolites by Artificial Neural Network Analysis fromin VivoSingle-Voxel1H NMR Spectra

    Article • Journal of Magnetic Resonance, September 1998, Elsevier

    Professor Risto A Kauppinen

  115. Noninvasive Detection of Cerebral Hypoperfusion and Reversible Ischemia from Reductions in the Magnetic Resonance Imaging Relaxation Time, T2

    Article • Journal of Cerebral Blood Flow & Metabolism, August 1998, SAGE Publications

    Professor Risto A Kauppinen

  116. Neuroprotective role of ornithine decarboxylase activation in transient focal cerebral ischaemia: a study using ornithine decarboxylase-overexpressing transgenic rats

    Article • European Journal of Neuroscience, June 1998, Wiley

    Professor Risto A Kauppinen

  117. Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging

    Article • Nature Reports Stem Cells, February 1998, Springer Science + Business Media

    Professor Risto A Kauppinen

  118. QUANTITATIVE DETERMINATION OF GLUTAMATE TURNOVER BY 1 H-OBSERVED, 13 C-EDITED NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY IN THE CEREBRAL CORTEX EX VIVO : INTERRELATIONSHIPS WITH OXYGEN CONSUMPTION

    Article • Neurochemistry International, July 1997, Elsevier

    Professor Risto A Kauppinen, PhD Mikko P Turunen

  119. Selegiline treatment after transient global ischemia in gerbils enhances the survival of CA1 pyramidal cells in the hippocampus

    Article • Brain Research, May 1997, Elsevier

    Professor Risto A Kauppinen

  120. Visual Activation in α‐Chloralose‐anaesthetized Cats Does Not Cause Lactate Accumulation in the Visual Cortex as Detected by [1HINMR Difference Spectroscopy

    Article • European Journal of Neuroscience, April 1997, Wiley

    Professor Risto A Kauppinen

  121. Intracellular chelation of calcium prevents cell damage following severe hypoxia in the rat cerebral cortex as studied by NMR spectroscopy ex vivo

    Article • Cell Calcium, December 1996, Elsevier

    Professor Risto A Kauppinen

  122. Increased macromolecular resonances in the rat cerebral cortex during severe energy failure as detected by 1H nuclear magnetic resonance spectroscopy

    Article • Neuroscience Letters, July 1996, Elsevier

    Professor Risto A Kauppinen

  123. Automated classification of human brain tumours by neural network analysis using in vivo H magnetic resonance spectroscopic metabolite phenotypes

    Article • Neuroreport, July 1996, Wolters Kluwer Health

    Professor Risto A Kauppinen

  124. Transgenic animals as models in the study of the neurobiological role of polyamines

    Article • Progress in Neurobiology, December 1995, Elsevier

    Professor Risto A Kauppinen

  125. Life‐long over‐expression of ornithine decarboxylase (ODC) gene in transgenic mice does not lead to generally enhanced tumorigenesis or neuronal degeneration

    Article • International Journal of Cancer, November 1995, Wiley

    Professor Risto A Kauppinen

  126. Radiation-induced changes in human brain metabolites as studied by 1H nuclear magnetic resonance spectroscopy in vivo

    Article • International Journal of Radiation Oncology*Biology*Physics, October 1995, Elsevier

    Professor Risto A Kauppinen

  127. Cerebral Energy Metabolism and Immediate Early Gene Induction Following Severe Incomplete Ischaemia in Transgenic Mice Overexpressing the Human Ornithine Decarboxylase Gene: Evidence that Putrescine is not Neurotoxic In Vivo

    Article • European Journal of Neuroscience, September 1995, Wiley

    Professor Risto A Kauppinen

  128. Quantification of metabolites from single-voxelin vivo 1H NMR data of normal human brain by means of time-domain data analysis

    Article • Magnetic Resonance Materials in Physics Biology and Medicine, September 1995, Springer Science + Business Media

    Professor Risto A Kauppinen

  129. Glucose Metabolism in the Developing Cerebral Cortex as Detected by 1H{13C} Nuclear Magnetic Resonance Spectroscopy Ex Vivo

    Article • Journal of Neurochemistry, January 1995, Wiley

    Professor Risto A Kauppinen

  130. Choline‐Containing Compounds in Human Astrocytomas Studied by 1H NMR Spectroscopy In Vivo and In Vitro

    Article • Journal of Neurochemistry, October 1994, Wiley

    Professor Risto A Kauppinen

  131. Nuclear magnetic resonance spectroscopy studies of the brain

    Article • Progress in Neurobiology, September 1994, Elsevier

    Professor Risto A Kauppinen

  132. Quantitative Metabolite Patterns of Human Brain Tumors

    Article • Journal of Computer Assisted Tomography, September 1994, Wolters Kluwer Health

    Professor Risto A Kauppinen

  133. Lactate efflux and intracellular pH during severe hypoxia in rat cerebral cortex in vitro studied by nuclear magnetic resonance spectroscopy

    Article • Neuroscience Letters, August 1994, Elsevier

    Professor Risto A Kauppinen

  134. Decrease in brain choline‐containing compounds following a short period of global ischemia in gerbils as detected by 1H NMR spectroscopy in vivo

    Article • NMR in Biomedicine, August 1994, Wiley

    Professor Risto A Kauppinen

  135. Regulation of Intracellular pH in Guinea Pig Cerebral Cortex Ex Vivo Studied by 31P and 1H Nuclear Magnetic Resonance Spectroscopy: Role of Extracellular Bicarbonate and Chloride

    Article • Journal of Neurochemistry, February 1994, Wiley

    Professor Risto A Kauppinen

  136. Extracellular pH and buffering power determine intracellular pH in cortical brain slices during and following hypoxia

    Article • Neuroreport, December 1993, Wolters Kluwer Health

    Professor Risto A Kauppinen

  137. 1H Nuclear magnetic resonance spectroscopy identifies neural cell types: a promising step for neuroimaging?

    Article • Trends in Neurosciences, October 1993, Elsevier

    Professor Risto A Kauppinen

  138. Nuclear magnetic resonance spectroscopy of plasma to distinguish between malignant and benign diseases causing jaundice and cholestasis

    Article • Journal of Cancer Research and Clinical Oncology, October 1993, Springer Science + Business Media

    Professor Risto A Kauppinen

  139. Quantitative analysis of 1H NMR detected proteins in the rat cerebral cortex in vivo and in vitro

    Article • NMR in Biomedicine, July 1993, Wiley

    Professor Risto A Kauppinen

  140. 1H Nuclear Magnetic Resonance Spectroscopy Study of Cerebral Glutamate in an Ex Vivo Brain Preparation of Guinea Pig

    Article • Journal of Neurochemistry, April 1993, Wiley

    Professor Risto A Kauppinen

  141. Delayed increase in intracellular Na+ in cerebral cortical slices during severe hypoxia as measured by double quantum filtered 23 Na+ NMR

    Article • Neuroreport, February 1993, Wolters Kluwer Health

    Professor Risto A Kauppinen

  142. Contribution of cytoplasmic polypeptides to the 1H NMR spectrum of developing rat cerebral cortex

    Article • Magnetic Resonance in Medicine, June 1992, Wiley

    Professor Risto A Kauppinen

  143. Nuclear Magnetic Resonance Spectroscopy Study on Energy Metabolism, Intracellular pH, and Free Mg2+ Concentration in the Brain of Transgenic Mice Overexpressing Human Ornithine Decarboxylase Gene

    Article • Journal of Neurochemistry, March 1992, Wiley

    Professor Risto A Kauppinen

  144. Detection of Mobile Proteins by Proton Nuclear Magnetic Resonance Spectroscopy in the Guinea Pig Brain Ex Vivo and Their Partial Purification

    Article • Journal of Neurochemistry, March 1992, Wiley

    Professor Risto A Kauppinen

  145. Nondestructive Detection of Glutamate by 1H Nuclear Magnetic Resonance Spectroscopy in Cortical Brain Slices from the Guinea Pig: Evidence for Changes in Detectability During Severe Anoxic Insults

    Article • Journal of Neurochemistry, October 1991, Wiley

    Professor Risto A Kauppinen

  146. Effects of ammonium on energy metabolism and intracellular pH in guinea pig cerebral cortex studied by 31P and 1H nuclear magnetic resonance spectroscopy

    Article • Neurochemistry International, January 1991, Elsevier

    Professor Risto A Kauppinen

  147. Interrelationships (Between Glucose Metabolism, Energy State, and the Cytosolic Free Calcium Concentration in Cortical Synjaptosomes from the Guinea Pig

    Article • Journal of Neurochemistry, September 1989, Wiley

    Professor Risto A Kauppinen

  148. Observation of Cerebral Metabolites in an Animal Model of Acute Liver Failure In Vivo: A 1H and 31P Nuclear Magnetic Resonance Study

    Article • Journal of Neurochemistry, July 1989, Wiley

    Professor Risto A Kauppinen

  149. Chloride‐Dependent Uncoupling of Oxidative Phosphorylation by Triethyllead and Triethyltin Increases Cytosolic Free Calcium in Guinea Pig Cerebral Cortical Synaptosomes

    Article • Journal of Neurochemistry, November 1988, Wiley

    Professor Risto A Kauppinen

  150. Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, September 1987, Elsevier

    Professor Risto A Kauppinen

  151. Failure to Maintain Glycolysis in Anoxic Nerve Terminals

    Article • Journal of Neurochemistry, December 1986, Wiley

    Professor Risto A Kauppinen

  152. Divalent cation modulation of the ionic permeability of the synaptosomal plasma membrane

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, August 1986, Elsevier

    Professor Risto A Kauppinen

  153. Synaptosomal bioenergetics

    Article • European Journal of Biochemistry, July 1986, Wiley

    Professor Risto A Kauppinen

  154. Pyruvate utilization by synaptosomes is independent of calcium

    Article • FEBS Letters, April 1986, Wiley

    Professor Risto A Kauppinen

  155. Mitochondrial membrane potential, transmembrane difference in the NAD+ redox potential and the equilibrium of the glutamate-aspartate translocase in the isolated perfused rat heart

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, December 1983, Elsevier

    Professor Risto A Kauppinen

  156. Proton electrochemical potential of the inner mitochondrial membrane in isolated perfused rat hearts, as measured by exogenous probes

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, October 1983, Elsevier

    Professor Risto A Kauppinen

  157. Subcellular distribution of phosphagens in isolated perfused rat heart

    Article • FEBS Letters, April 1980, Wiley

    Professor Risto A Kauppinen