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  1. Chemical Standardization of Milk Thistle (Silybum marianum L.) Extract Using UHPLC-MS/MS and the Method of Standard Addition

    Article • Journal of the American Society for Mass Spectrometry, July 2024, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  2. Short-term treatment with cholestyramine increases long-acting anticoagulant rodenticide clearance from rabbits without affecting plasma vitamin K1 levels or blood coagulation

    Article • Toxicological Sciences, April 2024, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  3. In vitro inhibition of human cytochrome P450 enzymes by licoisoflavone B from Glycyrrhiza uralensis Fisch. ex DC

    Article • Toxicological Sciences, August 2023, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  4. Antiviral activities of hemp cannabinoids

    Article • Clinical Science, April 2023, Portland Press Ltd.

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  5. Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants

    Article • Drug Metabolism and Disposition, November 2022, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  6. Pharmacokinetics and Early Tumor Response to Conventional Transarterial Chemoembolization with Sorafenib and Doxorubicin in a VX2 Rabbit Tumor Model

    Article • Journal of Vascular and Interventional Radiology, October 2022, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  7. CRISPR-Cas9 Knock-In of T513M and G41S Mutations in the Murine β–Galactosyl-Ceramidase Gene Re-capitulates Early-Onset and Adult-Onset Forms of Krabbe Disease

    Article • Frontiers in Molecular Neuroscience, May 2022, Frontiers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  8. Inhaled synthetic cannabinoids laced with long-acting anticoagulant rodenticides: a clear and present worldwide danger

    Article • Toxicology Communications, January 2022, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  9. Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants

    Article • Journal of Natural Products, January 2022, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  10. The Pathogenic Sphingolipid Psychosine is Secreted in Extracellular Vesicles in the Brain of a Mouse Model of Krabbe Disease

    Article • ASN NEURO, January 2022, SAGE Publications

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  11. Advances in Magnetic Microbead Affinity Selection Screening: Discovery of Natural Ligands to the SARS-CoV-2 Spike Protein

    Article • Journal of the American Society for Mass Spectrometry, December 2021, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  12. Drug discovery from natural products using affinity selection-mass spectrometry

    Article • Drug Discovery Today Technologies, December 2021, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  13. Living with a giant, flowering parasite: metabolic differences between Tetrastigma loheri Gagnep. (Vitaceae) shoots uninfected and infected with Rafflesia (Rafflesiaceae) and potential applications for propagation

    Article • Planta, November 2021, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  14. Effects of Pasture Type on Metabolism, Liver and Kidney Function, Antioxidant Status, and Plant Secondary Compounds in Plasma of Grazing, Jersey Dairy Cattle During Mid-lactation

    Article • Frontiers in Animal Science, October 2021, Frontiers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  15. Isolation and elucidation of two isoflavonoids from an American Indian plant, Amorpha canescens Pursh, using Magnetic Microbead Affinity Selection Screening (MagMASS) for estrogen receptor alpha ligands

    Article • Phytochemistry Letters, October 2021, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  16. Severe Vitamin K-dependent Coagulopathy from Rodenticide-contaminated Synthetic Cannabinoids: Emergency Department Presentations

    Article • Western Journal of Emergency Medicine, July 2021, Western Journal of Emergency Medicine

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  17. Pharmacokinetics of a Single Dose of Turmeric Curcuminoids Depends on Formulation: Results of a Human Crossover Study

    Article • Journal of Nutrition, July 2021, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  18. Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease

    Article • Molecular Therapy, May 2021, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  19. Conventional versus drug-eluting embolic transarterial chemoembolization with doxorubicin: comparative drug delivery, pharmacokinetics, and treatment response in a rabbit VX2 tumor model

    Article • Drug Delivery and Translational Research, April 2021, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  20. Chiral liquid chromatography-tandem mass spectrometry analysis of superwarfarin rodenticide stereoisomers – Bromadiolone, difenacoum and brodifacoum – In human plasma

    Article • Journal of Chromatography B, February 2021, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  21. Brodifacoum pharmacokinetics in acute human poisoning: implications for estimating duration of vitamin K therapy

    Article • Toxicology Communications, January 2021, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  22. Unmet clinical laboratory need in patients hospitalized for acute poisoning from long-acting anticoagulant rodenticides

    Article • Toxicology Communications, January 2021, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  23. No Clinically Relevant Pharmacokinetic Interactions of a Red Clover Dietary Supplement with Cytochrome P450 Enzymes in Women

    Article • Journal of Agricultural and Food Chemistry, November 2020, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  24. Affinity selection–mass spectrometry for the discovery of pharmacologically active compounds from combinatorial libraries and natural products

    Article • Journal of Mass Spectrometry, September 2020, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  25. Single Laboratory Validation of UHPLC-MS/MS Assays for Six Milk Thistle Flavonolignans in Human Serum

    Article • Journal of AOAC International, August 2020, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  26. Pharmacokinetic Interactions of a Hop Dietary Supplement with Drug Metabolism in Perimenopausal and Postmenopausal Women

    Article • Journal of Agricultural and Food Chemistry, April 2020, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  27. Separation and Quantification of Superwarfarin Rodenticide Diastereomers—Bromadiolone, Difenacoum, Flocoumafen, Brodifacoum, and Difethialone—in Human Plasma

    Article • Journal of AOAC International, March 2020, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  28. Single-Laboratory Validation of UHPLC-MS/MS Assays for Red Clover Isoflavones in Human Serum and Dietary Supplements

    Article • Journal of AOAC International, March 2020, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  29. Classification of Flavonoid Metabolomes via Data Mining and Quantification of Hydroxyl NMR Signals

    Article • Analytical Chemistry, February 2020, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  30. Catherine Fenselau: A distinguished career dedicated to biomedical mass spectrometry

    Article • Journal of Mass Spectrometry, February 2020, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  31. Effects of vitamin K1 treatment on plasma concentrations of long-acting anticoagulant rodenticide enantiomers following inhalation of contaminated synthetic cannabinoids

    Article • Clinical Toxicology, November 2019, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  32. Formation of (2R)- and (2S)-8-Prenylnaringenin Glucuronides by Human UDP-Glucuronosyltransferases

    Article • Journal of Agricultural and Food Chemistry, September 2019, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  33. Coagulopathy After Synthetic Cannabinoid Use: A Case Report

    Article • Annals of Internal Medicine, August 2019, American College of Physicians

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  34. Correction to The Multiple Biological Targets of Hops and Bioactive Compounds

    Article • Chemical Research in Toxicology, August 2019, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  35. Ion mobility‐mass spectrometry for the separation and analysis of procyanidins

    Article • Journal of Mass Spectrometry, June 2019, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  36. The Multiple Biological Targets of Hops and Bioactive Compounds

    Article • Chemical Research in Toxicology, January 2019, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  37. Rapid Determination of Procyanidins Using MALDI-ToF/ToF Mass Spectrometry

    Article • Journal of Agricultural and Food Chemistry, October 2018, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  38. Matrix-Assisted Laser Desorption/Ionization Imaging Portrays Locoregional Drug Delivery

    Article • Journal of Vascular and Interventional Radiology, August 2018, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  39. Standard Method Performance Requirements (SMPRs®) 2018.004: Determination of trans Resveratrol in Dietary Supplements and Dietary Ingredients

    Article • Journal of AOAC International, July 2018, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  40. Standard Method Performance Requirements (SMPRs®) 2018.006: Determination of Select Flavonoids from Skullcap

    Article • Journal of AOAC International, July 2018, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  41. Standard Method Performance Requirements (SMPRs®) 2018.007: Identification of Skullcap in Raw Materials, Skullcap-Based Dietary Ingredients, and Dietary Supplements

    Article • Journal of AOAC International, July 2018, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  42. The Bile Sequestrant Cholestyramine Increases Survival in a Rabbit Model of Brodifacoum Poisoning

    Article • Toxicological Sciences, June 2018, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  43. Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication

    Article • Journal of Natural Products, April 2018, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  44. Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe’s Disease after Global Gene Therapy

    Article • Molecular Therapy, March 2018, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  45. Analysis of age-related changes in psychosine metabolism in the human brain

    Article • PLoS ONE, February 2018, PLOS

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  46. Does doxorubicin survive thermal ablation? Results of an ex vivo bench top study

    Article • Diagnostic and Interventional Radiology, January 2018, Journal of Clinical Research of Pediatric Endocrinology

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  47. Treatment for long acting anticoagulant rodenticide poisoning – beyond INR monitoring?

    Article • Toxicology Communications, January 2018, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  48. Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry

    Article • Analytical and Bioanalytical Chemistry, November 2017, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  49. Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents

    Article • European Journal of Pharmaceutical Sciences, November 2017, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  50. Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats

    Article • The Journal of Steroid Biochemistry and Molecular Biology, November 2017, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  51. A standardized Humulus lupulus (L.) ethanol extract partially prevents ovariectomy-induced bone loss in the rat without induction of adverse effects in the uterus

    Article • Phytomedicine, October 2017, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  52. Isolation and structural characterization of dihydrobenzofuran congeners of licochalcone A

    Article • Fitoterapia, September 2017, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  53. DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women’s Health

    Article • Journal of Natural Products, August 2017, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  54. Collision‐induced dissociation of phenethylamides: role of ion‐neutral complexes

    Article • Rapid Communications in Mass Spectrometry, July 2017, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  55. Prostate Cancer Risk and DNA Methylation Signatures in Aging Rats following Developmental BPA Exposure: A Dose–Response Analysis

    Article • Environmental Health Perspectives, July 2017, Environmental Health Perspectives

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  56. The Long-Lasting Rodenticide Brodifacoum Induces Neuropathology in Adult Male Rats

    Article • Toxicological Sciences, June 2017, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  57. Psychosine enhances the shedding of membrane microvesicles: Implications in demyelination in Krabbe’s disease

    Article • PLoS ONE, May 2017, PLOS

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  58. Procyanidins: a comprehensive review encompassing structure elucidation via mass spectrometry

    Article • Phytochemistry Reviews, May 2017, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  59. Does doxorubicin survive thermal ablation? Results of an ex vivo bench top study

    Article • Journal of Vascular and Interventional Radiology, February 2017, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  60. AOAC SMPR 2016.017:Standard Method Performance Requirements (SMPRs)for Quantitative Measurement of Vitamin B12 in Dietary Supplements and Ingredients

    Article • Journal of AOAC International, January 2017, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  61. Role of ammonium in the ionization of phosphatidylcholines during electrospray mass spectrometry

    Article • Rapid Communications in Mass Spectrometry, December 2016, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  62. Development of a Magnetic Microbead Affinity Selection Screen (MagMASS) Using Mass Spectrometry for Ligands to the Retinoid X Receptor-α

    Article • Journal of the American Society for Mass Spectrometry, December 2016, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  63. Magnetic Microbead Affinity Selection Screening (MagMASS) of Botanical Extracts for Inhibitors of 15-Lipoxygenase

    Article • Journal of Natural Products, November 2016, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  64. Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS

    Article • Journal of Agricultural and Food Chemistry, October 2016, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  65. Sulfatides in extracellular vesicles isolated from plasma of multiple sclerosis patients

    Article • Journal of Neuroscience Research, August 2016, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  66. The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures

    Article • Annals of the New York Academy of Sciences, May 2016, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  67. Evidence supporting the conceptual framework of cancer chemoprevention in canines

    Article • Scientific Reports, May 2016, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  68. Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis

    Article • American Journal of Respiratory Cell and Molecular Biology, May 2016, American Thoracic Society

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  69. Comment on “Optimal Exposure Biomarkers for Nonpersistent Chemicals in Environmental Epidemiology”

    Article • Environmental Health Perspectives, April 2016, Environmental Health Perspectives

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  70. American Indian Botanicals As Possible Alternatives To Hormone Therapy During Menopause

    Article • Planta Medica, March 2016, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  71. Erratum to: A round robin approach to the analysis of bisphenol a (BPA) in human blood samples

    Article • Environmental Health, March 2016, Springer Science + Business Media

    Vasantha Padmanabhan, Professor of Pharmaceutical Sciences Richard B. van Breemen

  72. Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer

    Article • BMC Gastroenterology, February 2016, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  73. LC–MS-MS Analysis of Brodifacoum Isomers in Rat Tissue

    Article • Journal of Analytical Toxicology, February 2016, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  74. Improved Quantification of Free and Ester-Bound Gallic Acid in Foods and Beverages by UHPLC-MS/MS

    Article • Journal of Agricultural and Food Chemistry, February 2016, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  75. Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa

    Article • Journal of Natural Products, January 2016, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  76. Determination of bisphenol A‐glucuronide in human urine using ultrahigh‐pressure liquid chromatography/tandem mass spectrometry

    Article • Rapid Communications in Mass Spectrometry, January 2016, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  77. Standardized Grape Powder for Basic and Clinical Research

    Article • January 2016, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  78. Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women’s Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A

    Article • Chemical Research in Toxicology, November 2015, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  79. Botanical dietary supplements might enhance or diminish the efficacy of prescription drugs

    Article • Drug Metabolism and Disposition, October 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  80. A Phase II Randomized Trial of Lycopene-Rich Tomato Extract Among Men with High-Grade Prostatic Intraepithelial Neoplasia

    Article • Nutrition and Cancer, September 2015, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  81. High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions

    Article • Drug Metabolism and Disposition, August 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  82. Development of Safe and Effective Botanical Dietary Supplements

    Article • Journal of Medicinal Chemistry, July 2015, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  83. High throughput screening of natural products utilizing pulsed ultrafiltration or magnetic microbead affinity selection with UHPLC-MS/MS

    Article • Planta Medica, June 2015, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  84. Pharmacokinetic interactions between drugs and botanical dietary supplements

    Article • Planta Medica, June 2015, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  85. Pharmacokinetic interactions between drugs and botanical dietary supplements

    Article • Planta Medica, June 2015, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  86. A designer Licorice extract: Selective depletion of glabridin and congeneric metabolites by countercurrent separation

    Article • Planta Medica, June 2015, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  87. American Indian botanicals: possible alternatives to hormone therapy during menopause

    Article • Planta Medica, June 2015, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  88. Can women's health botanicals prevent estrogen carcinogenesis?

    Article • Planta Medica, June 2015, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  89. High-throughput cytochrome P450 inhibition cocktail assay for evaluating possible drug-botanical interactions: Application to licorice

    Article • Planta Medica, June 2015, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  90. Quantification of polyphenols in freeze-dried table grape powder

    Article • Planta Medica, June 2015, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  91. Quantitation of major indole and oxindole alkaloids from different kratom (Mitrigyna speciosa) strain extracts using UHPLC-MS/MS

    Article • Planta Medica, June 2015, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  92. Development of safe and effective botanical dietary supplements

    Article • Planta Medica, June 2015, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  93. Pharmacokinetic study of conventional sorafenib chemoembolization in a rabbit VX2 liver tumor model

    Article • Diagnostic and Interventional Radiology, May 2015, Journal of Clinical Research of Pediatric Endocrinology

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  94. Detection of Reactive Metabolites Using Isotope-Labeled Glutathione Trapping and Simultaneous Neutral Loss and Precursor Ion Scanning with Ultra-High-Pressure Liquid Chromatography Triple Quadruple Mass Spectrometry

    Article • Analytical Chemistry, March 2015, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  95. Dysfunction of Platelet-derived Growth Factor Receptor α (PDGFRα) Represses the Production of Oligodendrocytes from Arylsulfatase A-deficient Multipotential Neural Precursor Cells

    Article • Journal of Biological Chemistry, March 2015, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  96. Mechanism of Neuromuscular Dysfunction in Krabbe Disease

    Article • Journal of Neuroscience, January 2015, Society for Neuroscience

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  97. Nitrogen-Containing Constituents of Black Cohosh: Chemistry, Structure Elucidation, and Biological Activities

    Article • January 2015, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  98. Distribution of C16:0, C18:0, C24:1, and C24:0 sulfatides in central nervous system lipid rafts by quantitative ultra-high-pressure liquid chromatography tandem mass spectrometry

    Article • Analytical Biochemistry, December 2014, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  99. K-Targeted Metabolomic Analysis Extends Chemical Subtraction to DESIGNER Extracts: Selective Depletion of Extracts of Hops (Humulus lupulus)

    Article • Journal of Natural Products, December 2014, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  100. Pharmacokinetics of prenylated hop phenols in women following oral administration of a standardized extract of hops

    Article • Molecular Nutrition & Food Research, September 2014, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  101. Orthogonal Analysis Underscores the Relevance of Primary and Secondary Metabolites in Licorice

    Article • Journal of Natural Products, July 2014, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  102. UHPLC-MS/MS detection of reactive metabolites trapped as GSH conjugates from plant extracts

    Article • Planta Medica, July 2014, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  103. DART-MS analysis of Glycyrrhiza species

    Article • Planta Medica, July 2014, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  104. Development and application of a magnetic bead-based protein-ligand binding assay for screening of natural products

    Article • Planta Medica, July 2014, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  105. Safety of botanical dietary supplements used by menopausal women: In vitro investigations of drug-botanical interactions

    Article • Planta Medica, July 2014, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  106. Targeted purification of glabridin and congeneric metabolites from Glycyrrhiza glabra L.

    Article • Planta Medica, July 2014, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  107. Nature’s Palette: The Search for Natural Blue Colorants

    Article • Journal of Agricultural and Food Chemistry, July 2014, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  108. Antiproliferative and quinone reductase-inducing activities of withanolides derivatives

    Article • European Journal of Medicinal Chemistry, July 2014, Elsevier

    Dr. José M. Padrón, Professor of Pharmaceutical Sciences Richard B. van Breemen

  109. Biological and chemical standardization of a hop (Humulus lupulus) botanical dietary supplement

    Article • Biomedical Chromatography, May 2014, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  110. Metabolism of Nω‐methylserotonin, a serotonergic constituent of black cohosh (Cimicifuga racemosa, L. (Nutt.)), by human liver microsomes

    Article • Biomedical Chromatography, May 2014, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  111. A round robin approach to the analysis of bisphenol a (BPA) in human blood samples

    Article • Environmental Health, April 2014, Springer Science + Business Media

    Vasantha Padmanabhan, Professor of Pharmaceutical Sciences Richard B. van Breemen

  112. The potent and selective α 4 β 2*/ α 6*‐nicotinic acetylcholine receptor partial agonist 2‐[5‐[5‐(( S )Azetidin‐2‐ylmethoxy)‐3‐pyridinyl]‐3‐isoxazolyl]ethan...

    Article • Pharmacology Research & Perspectives, March 2014, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  113. Bisphenol A Promotes Human Prostate Stem-Progenitor Cell Self-Renewal and Increases In Vivo Carcinogenesis in Human Prostate Epithelium

    Article • Endocrinology, March 2014, Endocrine Society

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  114. Inhibition of human cytochrome P450 enzymes by hops (Humulus lupulus) and hop prenylphenols

    Article • European Journal of Pharmaceutical Sciences, March 2014, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  115. Neuronal inclusions of α‐synuclein contribute to the pathogenesis of Krabbe disease

    Article • The Journal of Pathology, February 2014, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  116. Food Matrix Effects on Bioaccessibility of β-Carotene Can be Measured in an in Vitro Gastrointestinal Model

    Article • Journal of Agricultural and Food Chemistry, January 2014, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  117. Bioactive Lysophosphatidylcholine 16:0 and 18:0 Are Elevated in Lungs of Asthmatic Subjects

    Article • Allergy Asthma and Immunology Research, January 2014, The Korean Academy of Asthma, Allergy and Clinical Immunology and The Korean Academy of Pediatric Al

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  118. Stimulated Bronchial Epithelial Cells Release Bioactive Lysophosphatidylcholine 16:0, 18:0, and 18:1

    Article • Allergy Asthma and Immunology Research, January 2014, The Korean Academy of Asthma, Allergy and Clinical Immunology and The Korean Academy of Pediatric Al

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  119. Lipidated steroid saponins from Dioscorea villosa (wild yam)

    Article • Fitoterapia, December 2013, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  120. Species-specific Standardisation of Licorice by Metabolomic Profiling of Flavanones and Chalcones

    Article • Phytochemical Analysis, November 2013, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  121. Photoreactive “Nanorulers” Detect a Novel Conformation of Full Length HDAC3-SMRT Complex in Solution

    Article • ACS Chemical Biology, October 2013, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  122. Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles

    Article • European Journal of Medicinal Chemistry, October 2013, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  123. Correction to Diarylheptanoids from Dioscorea villosa (Wild Yam)

    Article • Journal of Natural Products, October 2013, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  124. Flaxseed enriched diet-mediated reduction in ovarian cancer severity is correlated to the reduction of prostaglandin E2 in laying hen ovaries

    Article • Prostaglandins Leukotrienes and Essential Fatty Acids, September 2013, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  125. Best Practice in Mass Spectrometry for LC‐MS

    Article • August 2013, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  126. Quantitative Analysis of Phytosterols in Edible Oils Using APCI Liquid Chromatography–Tandem Mass Spectrometry

    Article • Lipids, July 2013, Wiley

    Dr Jeffrey Hurst, Professor of Pharmaceutical Sciences Richard B. van Breemen

  127. Evaluation of Estrogenic Activity of Licorice Species in Comparison with Hops Used in Botanicals for Menopausal Symptoms

    Article • PLoS ONE, July 2013, PLOS

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  128. Levels of plasma sulfatides C18 : 0 and C24 : 1 correlate with disease status in relapsing–remitting multiple sclerosis

    Article • Journal of Neurochemistry, July 2013, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  129. Dynamic Relationships between Bioactive 2'-Hydroxychalcones and their Flavanone Isomers in Licorice (Glycyrrhiza glabra L. and Glycyrrhiza uralensis Fisch. ex DC.)

    Article • Planta Medica, July 2013, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  130. Metabolomic Mining of the Botanical Dietary Supplement Wild Yam (Dioscorea villosa L.)

    Article • Planta Medica, July 2013, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  131. Structure Determination of Isoxanthohumol and 8-Prenylnaringenin Glucuronides Formed by Human Liver Microsomes

    Article • Planta Medica, July 2013, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  132. UHPLC with High Performance Tandem Mass Spectrometry for Studies of Botanical Dietary Supplement Safety and Efficacy

    Article • Planta Medica, July 2013, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  133. Effects of Lycopene on Protein Expression in Human Primary Prostatic Epithelial Cells

    Article • Cancer Prevention Research, May 2013, American Association for Cancer Research (AACR)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  134. Transarterial Sorafenib Chemoembolization: Preliminary Study of Technical Feasibility in a Rabbit Model

    Article • Journal of Vascular and Interventional Radiology, May 2013, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  135. Transarterial sorafenib chemoembolization: preliminary study of technical feasibility in a rabbit model

    Article • Journal of Vascular and Interventional Radiology, April 2013, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  136. Robert J. Cotter (1943–2012)

    Article • Journal of the American Society for Mass Spectrometry, March 2013, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  137. Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo

    Article • Molecular Nutrition & Food Research, March 2013, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  138. Up-Regulation of Neurotrophic Factors by Cinnamon and its Metabolite Sodium Benzoate: Therapeutic Implications for Neurodegenerative Disorders

    Article • Journal of Neuroimmune Pharmacology, March 2013, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  139. Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with Chemopreventive Potential

    Article • Journal of Medicinal Chemistry, March 2013, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  140. Analytical Methods for Quantitation of Prenylated Flavonoids from Hops

    Article • Current Analytical Chemistry, January 2013, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  141. Isolation and Characterization of Natural Blue Pigments from Underexplored Sources

    Article • January 2013, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  142. Method Development and Validation for Ultra-High Pressure Liquid Chromatography/Tandem Mass Spectrometry Determination of Multiple Prostanoids in Biological Samples

    Article • Journal of AOAC International, January 2013, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  143. Pharmacokinetics and brain penetration of LF-3-88, (2-[5-[5-(2(S)-azetidinylmethoxyl)-3-pyridyl]-3-isoxazolyl]ethanol), a selective α4β2-nAChR partial agonist and promising antidepressant

    Article • Journal of Chromatography B, January 2013, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  144. Diarylheptanoids from Dioscorea villosa (Wild Yam)

    Article • Journal of Natural Products, December 2012, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  145. Identification, Synthesis, and Biological Evaluation of Metabolites of the Experimental Cancer Treatment Drugs Indotecan (LMP400) and Indimitecan (LMP776) and Investigation of Isomerically Hydroxylated Indenoisoquinoline Analogues as Topoisomerase I Po...

    Article • Journal of Medicinal Chemistry, December 2012, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  146. Analytical Methods for Quantitation of Prenylated Flavonoids from Hops

    Article • Current Analytical Chemistry, December 2012, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  147. Analytical Methods for Quantitation of Prenylated Flavonoids from Hops

    Article • Current Analytical Chemistry, December 2012, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  148. Method Development and Validation for Ultra-High-Pressure LC/MS/MS Determination of Hop Prenylflavonoids in Human Serum

    Article • Journal of AOAC International, November 2012, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  149. Novel histone deacetylase 8 ligands without a zinc chelating group: Exploring an ‘upside-down’ binding pose

    Article • Bioorganic & Medicinal Chemistry Letters, November 2012, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  150. Pivotal Role of Reactive Oxygen Species in Differential Regulation of Lipopolysaccharide-Induced Prostaglandins Production in Macrophages

    Article • Molecular Pharmacology, October 2012, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  151. Oral toxicity and pharmacokinetic studies of SHetA2, a new chemopreventive agent, in rats and dogs

    Article • Drug and Chemical Toxicology, September 2012, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  152. ERRATUM

    Article • Archives of Pathology & Laboratory Medicine, September 2012, Archives of Pathology and Laboratory Medicine

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  153. Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2

    Article • Bioorganic & Medicinal Chemistry Letters, August 2012, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  154. Characterization of the purple vacuolar pigment of Zygogonium ericatorum alga

    Article • Planta Medica, July 2012, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  155. Chemical subtraction of bioactive prenylated phenols generates knock-out extracts of hops (Humulus lupulus L.)

    Article • Planta Medica, July 2012, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  156. Comparative metabolomic fractionation and characterization of licorice roots

    Article • Planta Medica, July 2012, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  157. Constituents from the botanical dietary supplement wild yam

    Article • Planta Medica, July 2012, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  158. Detection of the Neurotoxin Psychosine in Samples of Peripheral Blood: Application in Diagnostics and Follow-up of Krabbe Disease

    Article • Archives of Pathology & Laboratory Medicine, July 2012, Archives of Pathology and Laboratory Medicine

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  159. Quantitative analysis of epicatechin metabolites in human serum using UHPLC-MS-MS

    Article • Planta Medica, July 2012, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  160. Identification, Synthesis, and Biological Evaluation of the Metabolites of 3-Amino-6-(3′-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6–36), a Promising Rexinoid Lead Compound for the Development of Cancer Chemothera...

    Article • Journal of Medicinal Chemistry, June 2012, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  161. Abstract 3564: A Phase II randomized trial of lycopene-rich tomato extract among men with high-grade prostatic intraepithelial neoplasia (HGPIN)

    Article • Cancer Research, April 2012, American Association for Cancer Research (AACR)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  162. Abstract 4781: Analysis of a new chemopreventative agent SHetA2 and its metabolites in Beagle dog liver and plasma

    Article • Cancer Research, April 2012, American Association for Cancer Research (AACR)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  163. Abstract LB-217: Lycopene and gene expression in benign prostate: a phase II randomized trial

    Article • Cancer Research, April 2012, American Association for Cancer Research (AACR)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  164. Mass spectrometric dereplication of nitrogen-containing constituents of black cohosh (Cimicifuga racemosa L.)

    Article • Fitoterapia, April 2012, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  165. Confirmation of drug delivery after liver chemoembolization: direct tissue doxorubicin measurement by UHPLC-MS-MS

    Article • Biomedical Chromatography, March 2012, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  166. Abstract No. 236: Ethiodized oil uptake does not predict doxorubicin drug delivery after chemoembolization in VX2 liver tumors

    Article • Journal of Vascular and Interventional Radiology, March 2012, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  167. Novel Marine Phenazines as Potential Cancer Chemopreventive and Anti-Inflammatory Agents

    Article • Marine Drugs, February 2012, MDPI AG

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  168. Atmospheric pressure chemical ionization tandem mass spectrometry of carotenoids

    Article • International Journal of Mass Spectrometry, February 2012, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  169. Ethiodized Oil Uptake Does Not Predict Doxorubicin Drug Delivery after Chemoembolization in VX2 Liver Tumors

    Article • Journal of Vascular and Interventional Radiology, February 2012, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  170. Screening for natural chemoprevention agents that modify human Keap1

    Article • Analytical Biochemistry, February 2012, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  171. Special issue honoring Catherine Fenselau

    Article • International Journal of Mass Spectrometry, February 2012, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  172. Integrated standardization concept for Angelica botanicals using quantitative NMR

    Article • Fitoterapia, January 2012, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  173. Associations between functional polymorphisms in antioxidant defense genes and urinary oxidative stress biomarkers in healthy, premenopausal women

    Article • Genes & Nutrition, November 2011, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  174. Competitive Enzymatic Interactions Determine the Relative Amounts of Prostaglandins E2 and D2

    Article • Journal of Pharmacology and Experimental Therapeutics, August 2011, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  175. In vitrometabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4

    Article • Xenobiotica, August 2011, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  176. Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity

    Article • Molecular Nutrition & Food Research, June 2011, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  177. Phytoconstituents from Vitex agnus-castus fruits

    Article • Fitoterapia, June 2011, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  178. Correction to Screening Natural Products for Inhibitors of Quinone Reductase-2 Using Ultrafiltration LC–MS

    Article • Analytical Chemistry, May 2011, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  179. Antioxidant Effects of Lycopene in African American Men with Prostate Cancer or Benign Prostate Hyperplasia: A Randomized, Controlled Trial

    Article • Cancer Prevention Research, May 2011, American Association for Cancer Research (AACR)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  180. Induction of Retinoid X Receptor Activity and Consequent Upregulation of p21WAF1/CIP1 by Indenoisoquinolines in MCF7 Cells

    Article • Cancer Prevention Research, April 2011, American Association for Cancer Research (AACR)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  181. Modification of Keap1 Cysteine Residues by Sulforaphane

    Article • Chemical Research in Toxicology, March 2011, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  182. Axonopathy is a compounding factor in the pathogenesis of Krabbe disease

    Article • Acta Neuropathologica, March 2011, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  183. Bioactive Compounds from the Fern Lepisorus contortus

    Article • Journal of Natural Products, January 2011, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  184. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale)

    Article • Fitoterapia, January 2011, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  185. Measurement of cyclooxygenase inhibition using liquid chromatography–tandem mass spectrometry

    Article • Journal of Pharmaceutical and Biomedical Analysis, January 2011, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  186. Screening Natural Products for Inhibitors of Quinone Reductase-2 Using Ultrafiltration LC−MS

    Article • Analytical Chemistry, December 2010, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  187. Persistence of psychosine in brain lipid rafts is a limiting factor in the therapeutic recovery of a mouse model for Krabbe disease

    Article • Journal of Neuroscience Research, December 2010, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  188. Collision Cross-Section Determination and Tandem Mass Spectrometric Analysis of Isomeric Carotenoids Using Electrospray Ion Mobility Time-of-Flight Mass Spectrometry

    Article • Analytical Chemistry, October 2010, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  189. Mass Spectrometry and Drug Discovery

    Article • September 2010, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  190. Rapid quantitative analysis of 8-iso-prostaglandin-F2α using liquid chromatography–tandem mass spectrometry and comparison with an enzyme immunoassay method

    Article • Analytical Biochemistry, September 2010, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  191. Chromatography—Advances in Environmental and Natural Products, Chemical Analysis and Synthesis

    Article • August 2010, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  192. Disposition of hop prenylflavonoids in human breast tissue

    Article • Molecular Nutrition & Food Research, July 2010, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  193. Quantitative analysis of 3α,6α,24-trihydroxy-24,24-di(trifluoromethyl)-5β-cholane, a potent synthetic steroidal liver X receptor agonist in plasma using liquid chromatography–tandem mass spectrometry

    Article • Journal of Chromatography B, July 2010, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  194. Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites

    Article • Journal of Medicinal Chemistry, June 2010, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  195. Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation

    Article • Pharmacological Research, June 2010, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  196. Redox Cycling of Catechol Estrogens Generating Apurinic/Apyrimidinic Sites and 8-oxo-Deoxyguanosine via Reactive Oxygen Species Differentiates Equine and Human Estrogens

    Article • Chemical Research in Toxicology, May 2010, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  197. Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata

    Article • Phytochemistry, April 2010, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  198. Vitamin A equivalency and apparent absorption of β-carotene in ileostomy subjects using a dual-isotope dilution technique

    Article • British Journal Of Nutrition, February 2010, Cambridge University Press

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  199. Cancer Chemopreventive Activity and Metabolism of Isoliquiritigenin, a Compound Found in Licorice

    Article • Cancer Prevention Research, February 2010, American Association for Cancer Research (AACR)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  200. Editorial

    Article • Combinatorial Chemistry & High Throughput Screening, January 2010, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  201. Abstract A68: Aromatase inhibition and chemopreventive potential of novel resveratrol derivatives

    Article • Cancer Prevention Research, January 2010, American Association for Cancer Research (AACR)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  202. Pharmacokinetics of 23-Epi-26-Deoxyactein in Women After Oral Administration of a Standardized Extract of Black Cohosh

    Article • Clinical Pharmacology & Therapeutics, December 2009, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  203. Identification and Quantification of Gingerols and Related Compounds in Ginger Dietary Supplements Using High-Performance Liquid Chromatography−Tandem Mass Spectrometry

    Article • Journal of Agricultural and Food Chemistry, November 2009, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  204. Binding Ensemble Profiling with Photoaffinity Labeling (BEProFL) Approach: Mapping the Binding Poses of HDAC8 Inhibitors

    Article • Journal of Medicinal Chemistry, November 2009, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  205. Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms

    Article • Menopause, November 2009, Wolters Kluwer Health

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  206. From Serendipity to Rational Antituberculosis Drug Discovery of Mefloquine-Isoxazole Carboxylic Acid Esters

    Article • Journal of Medicinal Chemistry, October 2009, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  207. Black Cohosh

    Article • Nutrition Today, July 2009, Wolters Kluwer Health

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  208. Screening Antioxidants Using LC-MS: Case Study with Cocoa

    Article • Journal of Agricultural and Food Chemistry, June 2009, American Chemical Society (ACS)

    Dr Jeffrey Hurst, Professor of Pharmaceutical Sciences Richard B. van Breemen

  209. Psychosine Accumulates in Membrane Microdomains in the Brain of Krabbe Patients, Disrupting the Raft Architecture

    Article • Journal of Neuroscience, May 2009, Society for Neuroscience

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  210. Estrogen Receptor α Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus

    Article • Journal of Biological Chemistry, March 2009, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  211. Guanidine Alkaloids and Pictet−Spengler Adducts from Black Cohosh (Cimicifuga racemosa)

    Article • Journal of Natural Products, February 2009, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  212. Combined hematopoietic and lentiviral gene‐transfer therapies in newborn Twitcher mice reveal contemporaneous neurodegeneration and demyelination in Krabbe disease

    Article • Journal of Neuroscience Research, January 2009, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  213. Phytochemistry of cimicifugic acids and associated bases in Cimicifuga racemosa root extracts

    Article • Phytochemical Analysis, January 2009, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  214. In Vitro Serotonergic Activity of Black Cohosh and Identification of Nω-Methylserotonin as a Potential Active Constituent

    Article • Journal of Agricultural and Food Chemistry, December 2008, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  215. Vitamin A equivalency of β-carotene in healthy adults: limitation of the extrinsic dual-isotope dilution technique to measure matrix effect

    Article • British Journal Of Nutrition, November 2008, Cambridge University Press

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  216. Structural Modulation of Oxidative Metabolism in Design of Improved Benzothiophene Selective Estrogen Receptor Modulators

    Article • Drug Metabolism and Disposition, October 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  217. In vivo estrogenic comparisons of Trifolium pratense (red clover) Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin

    Article • Chemico-Biological Interactions, October 2008, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  218. Multitargeted therapy of cancer by lycopene

    Article • Cancer Letters, October 2008, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  219. Angelica sinensis and Its Alkylphthalides Induce the Detoxification Enzyme NAD(P)H: Quinone Oxidoreductase 1 by Alkylating Keap1

    Article • Chemical Research in Toxicology, September 2008, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  220. Determination of Absolute Configurations of 4-Hydroxyequilenin-Cytosine and -Adenine Adducts by Optical Rotatory Dispersion, Electronic Circular Dichroism, Density Functional Theory Calculations, and Mass Spectrometry

    Article • Chemical Research in Toxicology, August 2008, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  221. Biotransformation of the Chemopreventive Agent 2′,4′,4-Trihydroxychalcone (Isoliquiritigenin) by UDP-Glucuronosyltransferases

    Article • Drug Metabolism and Disposition, July 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  222. An experimental implementation of chemical subtraction

    Article • Journal of Pharmaceutical and Biomedical Analysis, March 2008, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  223. Editorial from Editor-in-Chief

    Article • Combinatorial Chemistry & High Throughput Screening, February 2008, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  224. Ensuring the safety of botanical dietary supplements

    Article • American Journal of Clinical Nutrition, February 2008, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  225. Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent

    Article • Chemical Research in Toxicology, February 2008, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  226. Development of a Screening Assay for Ligands to the Estrogen Receptor Based on Magnetic Microparticles and LC-MS

    Article • Combinatorial Chemistry & High Throughput Screening, January 2008, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  227. An improved LC–MS/MS method for the quantification of prostaglandins E2 and D2 production in biological fluids

    Article • Analytical Biochemistry, January 2008, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  228. Autonomic Denervation of Lymphoid Organs Leads to Epigenetic Immune Atrophy in a Mouse Model of Krabbe Disease

    Article • Journal of Neuroscience, December 2007, Society for Neuroscience

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  229. Sites of alkylation of human Keap1 by natural chemoprevention agents

    Article • Journal of the American Society for Mass Spectrometry, December 2007, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  230. In Vitro Metabolism of Isoliquiritigenin by Human Liver Microsomes

    Article • Drug Metabolism and Disposition, November 2007, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  231. Screening for Ligands of Human Retinoid X Receptor-α Using Ultrafiltration Mass Spectrometry

    Article • Analytical Chemistry, November 2007, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  232. Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent

    Article • Chemical Research in Toxicology, October 2007, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  233. Regulation of cyclooxygenase-2 expression by small GTPase Rac2 in bone marrow macrophages

    Article • AJP Lung Cellular and Molecular Physiology, September 2007, American Physiological Society

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  234. Secondary Metabolites from Andrographis paniculata.

    Article • ChemInform, August 2007, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  235. Binding of the hop (Humulus lupulus L.) chalcone xanthohumol to cytosolic proteins in Caco‐2 intestinal epithelial cells

    Article • Molecular Nutrition & Food Research, July 2007, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  236. Chlorination Diversifies Cimicifuga racemosa Triterpene Glycosides

    Article • Journal of Natural Products, June 2007, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  237. Inhibitory κB Kinase 2 Activates Airway Epithelial Cells to Stimulate Bone Marrow Macrophages

    Article • American Journal of Respiratory Cell and Molecular Biology, May 2007, American Thoracic Society

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  238. Systematic investigation of lycopene effects in LNCaP cells by use of novel large‐scale proteomic analysis software

    Article • PROTEOMICS - CLINICAL APPLICATIONS, May 2007, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  239. The Role of Quality Assurance and Standardization in the Safety of Botanical Dietary Supplements

    Article • Chemical Research in Toxicology, March 2007, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  240. Coumaroyl Iridoids and a Depside from Cranberry (Vaccinium macrocarpon)

    Article • Journal of Natural Products, February 2007, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  241. Editorial [Hot Topic: Combinatorial Heterogeneous Catalysis (Part 1) (Guest Editor: Jozsef L. Margitfalvi)]

    Article • Combinatorial Chemistry & High Throughput Screening, January 2007, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  242. Editorial [Hot Topic: Combinatorial Heterogeneous Catalysis (Part 1) (Guest Editor: Jozsef L. Margitfalvi)]

    Article • Combinatorial Chemistry & High Throughput Screening, January 2007, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  243. Secondary Metabolites from Andrographis paniculata

    Article • Chemical and Pharmaceutical Bulletin, January 2007, Pharmaceutical Society of Japan

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  244. The stability of Z-ligustilide and its relevance for the biological evaluation of Angelica botanicals

    Article • Planta Medica, January 2007, Thieme Publishing Group

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  245. Effects of oral dosing paradigms (gavage versus diet) on pharmacokinetics and pharmacodynamics

    Article • Chemico-Biological Interactions, December 2006, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  246. (±)-(1S,2R,5S)-5-Amino-2-fluorocyclohex-3-enecarboxylic Acid. A Potent GABA Aminotransferase Inactivator that Irreversibly Inhibits via an Elimination−Aromatization Pathway

    Article • Biochemistry, November 2006, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  247. Absorption and subcellular localization of lycopene in human prostate cancer cells

    Article • Molecular Cancer Therapeutics, November 2006, American Association for Cancer Research (AACR)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  248. Quantitative analyses of β‐carotene and retinol in serum and feces in support of clinical bioavailability studies

    Article • Rapid Communications in Mass Spectrometry, July 2006, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  249. In Vitro Studies of Intestinal Permeability and Hepatic and Intestinal Metabolism of 8-Prenylnaringenin, a Potent Phytoestrogen from Hops (Humulus lupulus L.)

    Article • Pharmaceutical Research, May 2006, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  250. IDENTIFICATION OF HUMAN HEPATIC CYTOCHROME P450 ENZYMES INVOLVED IN THE METABOLISM OF 8-PRENYLNARINGENIN AND ISOXANTHOHUMOL FROM HOPS (HUMULUS LUPULUS L.)

    Article • Drug Metabolism and Disposition, April 2006, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  251. Chemical and analytical screening of some edible mushrooms

    Article • Food Chemistry, March 2006, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  252. The Chemical and Biologic Profile of a Red Clover (Trifolium pratense L.) Phase II Clinical Extract

    Article • The Journal of Alternative and Complementary Medicine, March 2006, Mary Ann Liebert Inc

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  253. Serotonergic Activity-Guided Phytochemical Investigation of the Roots of Angelica sinensis

    Article • Journal of Natural Products, February 2006, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  254. Editorial

    Article • Combinatorial Chemistry & High Throughput Screening, January 2006, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  255. GABAergic phthalide dimers fromAngelica sinensis (Oliv.) Diels

    Article • Phytochemical Analysis, January 2006, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  256. Three New Pentacyclic Triterpenes and Some Flavonoids from the Fruits of an Indian Ayurvedic Plant Dendrophthoe falcata and Their Estrogen Receptor Binding Activity

    Article • Chemical and Pharmaceutical Bulletin, January 2006, Pharmaceutical Society of Japan

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  257. Characterization of two new variants of human catechol O-methyltransferase in vitro

    Article • Cancer Letters, December 2005, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  258. Mass Spectrometry-Based Screening for Inhibitors of β-Amyloid Protein Aggregation

    Article • Analytical Chemistry, October 2005, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  259. Screening Method for the Discovery of Potential Cancer Chemoprevention Agents Based on Mass Spectrometric Detection of Alkylated Keap1

    Article • Analytical Chemistry, September 2005, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  260. Analysis of Protein Covalent Modification by Xenobiotics Using a Covert Oxidatively Activated Tag:  Raloxifene Proof-of-Principle Study

    Article • Chemical Research in Toxicology, September 2005, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  261. Caco-2 cell permeability assays to measure drug absorption

    Article • Expert Opinion on Drug Metabolism & Toxicology, August 2005, Informa Healthcare

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  262. Cimipronidine, a Cyclic Guanidine Alkaloid from Cimicifuga racemosa

    Article • Journal of Natural Products, August 2005, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  263. How Do Intermediate Endpoint Markers Respond to Lycopene in Men with Prostate Cancer or Benign Prostate Hyperplasia?

    Article • Journal of Nutrition, August 2005, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  264. Resveratrol inhibits rhabdomyosarcoma cell proliferation

    Article • European Journal of Cancer Prevention, August 2005, Wolters Kluwer Health

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  265. Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase

    Article • Chemical Research in Toxicology, July 2005, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  266. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

    Article • Proceedings of the National Academy of Sciences, July 2005, Proceedings of the National Academy of Sciences

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  267. Comparison of the in Vitro Estrogenic Activities of Compounds from Hops (Humulus lupulus) and Red Clover (Trifolium pratense)

    Article • Journal of Agricultural and Food Chemistry, July 2005, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  268. Functional and structural comparisons of cysteine residues in the Val108 wild type and Met108 variant of human soluble catechol O-methyltransferase

    Article • Chemico-Biological Interactions, April 2005, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  269. The soy isoflavone daidzein improves the capacity of tamoxifen to prevent mammary tumours

    Article • European Journal of Cancer, March 2005, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  270. Analysis of Carotenoids Using Atmospheric Pressure Chemical Ionization Mass Spectrometry

    Article • February 2005, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  271. Liquid chromatography/electrospray tandem mass spectrometry of terpenoid lactones in Ginkgo biloba

    Article • Journal of Mass Spectrometry, February 2005, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  272. Metabolism of xanthohumol and isoxanthohumol, prenylated flavonoids from hops (Humulus lupulus L.), by human liver microsomes

    Article • Journal of Mass Spectrometry, February 2005, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  273. Editorial from Editor-in-Chief

    Article • Combinatorial Chemistry & High Throughput Screening, February 2005, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  274. Ultrafiltration tandem mass spectrometry of estrogens for characterization of structure and affinity for human estrogen receptors

    Article • Journal of the American Society for Mass Spectrometry, February 2005, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  275. Bioactivation of the Selective Estrogen Receptor Modulator Acolbifene to Quinone Methides

    Article • Chemical Research in Toxicology, January 2005, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  276. Bioactivation of the Selective Estrogen Receptor Modulator Desmethylated Arzoxifene to Quinoids:  4‘-Fluoro Substitution Prevents Quinoid Formation

    Article • Chemical Research in Toxicology, January 2005, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  277. A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: Identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C

    Article • Journal of Molecular and Cellular Cardiology, January 2005, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  278. Mechanism of Inactivation of Inducible Nitric Oxide Synthase by Amidines. Irreversible Enzyme Inactivation without Inactivator Modification

    Article • Journal of the American Chemical Society, December 2004, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  279. Confusion regarding anticoagulant coumarins in dietary supplements

    Article • Clinical Pharmacology & Therapeutics, December 2004, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  280. Estrogens and Congeners from Spent Hops (Humuluslupulus)

    Article • Journal of Natural Products, December 2004, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  281. Analysis of GAA/TTC DNA triplexes using nuclear magnetic resonance and electrospray ionization mass spectrometry

    Article • Analytical Biochemistry, November 2004, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  282. Chemical and Biological Characterization and Clinical Evaluation of Botanical Dietary Supplements: A Phase I Red Clover Extract as a Model

    Article • Current Medicinal Chemistry, June 2004, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  283. In vitroassessment of intestinal permeability and hepatic metabolism of 4′-bromoflavone, a promising cancer chemopreventive agent

    Article • Xenobiotica, June 2004, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  284. Oxidation of Raloxifene to Quinoids:  Potential Toxic Pathways via a Diquinone Methide and o-Quinones

    Article • Chemical Research in Toxicology, May 2004, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  285. NEW METABOLIC PATHWAYS FOR FLAVANONES CATALYZED BY RAT LIVER MICROSOMES

    Article • Drug Metabolism and Disposition, March 2004, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  286. Equine Catechol Estrogen 4-Hydroxyequilenin Is a More Potent Inhibitor of the Variant Form of Catechol-O-Methyltransferase

    Article • Chemical Research in Toxicology, March 2004, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  287. Preface

    Article • Combinatorial Chemistry & High Throughput Screening, February 2004, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  288. Enhanced Ionization of Phosphorylated Peptides during MALDI TOF Mass Spectrometry

    Article • Analytical Chemistry, January 2004, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  289. METABOLISM OF 8-PRENYLNARINGENIN, A POTENT PHYTOESTROGEN FROM HOPS (HUMULUS LUPULUS), BY HUMAN LIVER MICROSOMES

    Article • Drug Metabolism and Disposition, January 2004, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  290. Ethanol inhibits benzo[a]pyrene-DNA adduct removal and increases 8-oxo-deoxyguanosine formation in human mammary epithelial cells

    Article • Cancer Letters, January 2004, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  291. Evaluation of Major Caffeic Acid Derivatives inEchinacea purpureaDietary Supplements by HPLC with Photodiode Array Detection and Electrospray Mass Spectrometry

    Article • Journal of Liquid Chromatography &amp Related Technologies, January 2004, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  292. Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry)

    Article • Phytomedicine, January 2004, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  293. Lycopene, a Dietary Cancer Chemopreventive Agent

    Article • January 2004, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  294. Increasing the Throughput and Productivity of Caco-2 Cell Permeability Assays Using Liquid Chromatography-Mass Spectrometry: Application to Resveratrol Absorption and Metabolism

    Article • Combinatorial Chemistry & High Throughput Screening, December 2003, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  295. A mechanism for substrate-Induced formation of 6-Hydroxyflavin mononucleotide catalyzed by C30A trimethylamine dehydrogenase

    Article • Bioorganic & Medicinal Chemistry Letters, November 2003, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  296. Inhibition of Rat Mammary Tumorigenesis by Concord Grape Juice Constituents

    Article • Journal of Agricultural and Food Chemistry, November 2003, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  297. Resveratrol in Raw and Baked Blueberries and Bilberries

    Article • Journal of Agricultural and Food Chemistry, August 2003, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  298. Quantitative analysis of betulinic acid in mouse, rat and dog plasma using electrospray liquid chromatography/mass spectrometry

    Article • Rapid Communications in Mass Spectrometry, August 2003, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  299. Identification of photocatalytic degradation products of diazinon in TiO2 aqueous suspensions using GC/MS/MS and LC/MS with quadrupole time-of-flight mass spectrometry

    Article • Journal of the American Society for Mass Spectrometry, August 2003, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  300. Black Cohosh Acts as a Mixed Competitive Ligand and Partial Agonist of the Serotonin Receptor

    Article • Journal of Agricultural and Food Chemistry, July 2003, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  301. Extraction of Carotenoids from Feces, Enabling the Bioavailability of β-Carotene to Be Studied in Indonesian Children

    Article • Journal of Agricultural and Food Chemistry, July 2003, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  302. Isolation and Characterization of Miscellaneous Secondary Metabolites of Deprea subtriflora

    Article • Journal of Natural Products, July 2003, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  303. In Vitro Formation of Quinoid Metabolites of the Dietary Supplement Cimicifuga racemosa (Black Cohosh)

    Article • Chemical Research in Toxicology, May 2003, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  304. Effect of Halogenated Substituents on the Metabolism and Estrogenic Effects of the Equine Estrogen, Equilenin

    Article • Chemical Research in Toxicology, May 2003, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  305. NMR study of fumarprotocetraric acid, a complex lichen depsidone derivative from Cladonia furcata

    Article • Magnetic Resonance in Chemistry, March 2003, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  306. Identification of caffeic acid derivatives in Actea racemosa (Cimicifuga racemosa, black cohosh) by liquid chromatography/tandem mass spectrometry

    Article • Rapid Communications in Mass Spectrometry, March 2003, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  307. Activity-Guided Isolation of Novel Norwithanolides from Deprea subtriflora with Potential Cancer Chemopreventive Activity

    Article • The Journal of Organic Chemistry, February 2003, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  308. Preface

    Article • Combinatorial Chemistry & High Throughput Screening, February 2003, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  309. Quantitative Analysis of Lycopene Isomers in Human Plasma Using High-Performance Liquid Chromatography−Tandem Mass Spectrometry

    Article • Analytical Chemistry, January 2003, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  310. Mass Spectrometry and Drug Discovery

    Article • January 2003, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  311. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol‐3‐sulfate

    Article • Rapid Communications in Mass Spectrometry, January 2003, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  312. Minor Withanolides from Physalis philadelphica: Structures, Quinone Reductase Induction Activities, and Liquid Chromatography (LC)-MS-MS Investigation as Artifacts

    Article • Chemical and Pharmaceutical Bulletin, January 2003, Pharmaceutical Society of Japan

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  313. p-Hydroxybenzoic Acid Alkyl Esters in Andrographis paniculata Herbs, Commercial Extracts, and Formulated Products

    Article • Journal of Agricultural and Food Chemistry, December 2002, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  314. Black Cohosh (Cimicifuga racemosa L.) Protects against Menadione-Induced DNA Damage through Scavenging of Reactive Oxygen Species:  Bioassay-Directed Isolation and Characterization of Active Principles

    Article • Journal of Agricultural and Food Chemistry, October 2002, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  315. Quantitative Determination of N7-Methyldeoxyguanosine and O6-Methyldeoxyguanosine in DNA by LC−UV−MS−MS

    Article • Analytical Chemistry, September 2002, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  316. Retinoic Acid Receptors and Retinoids Are Up-Regulated in the Developing and Adult Rat Prostate by Neonatal Estrogen Exposure

    Article • Endocrinology, September 2002, Endocrine Society

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  317. Evaluation of Commercial Ginkgo and Echinacea Dietary Supplements for Colchicine Using Liquid Chromatography-Tandem Mass Spectrometry

    Article • Chemical Research in Toxicology, August 2002, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  318. Low-Energy, Low-Yield Photoionization, and Production of 8-Oxo-2‘-deoxyguanosine and Guanine from 2‘-Deoxyguanosine

    Article • The Journal of Physical Chemistry B, July 2002, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  319. Oxidative DNA Damage Induced by Equine Estrogen Metabolites:  Role of Estrogen Receptor α

    Article • Chemical Research in Toxicology, March 2002, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  320. Liquid Chromatography−Mass Spectrometry of cis- and all-trans-Lycopene in Human Serum and Prostate Tissue after Dietary Supplementation with Tomato Sauce

    Article • Journal of Agricultural and Food Chemistry, March 2002, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  321. Preface

    Article • Combinatorial Chemistry & High Throughput Screening, February 2002, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  322. Screening Drugs for Metabolic Stability Using Pulsed Ultrafiltration Mass Spectrometry

    Article • Combinatorial Chemistry & High Throughput Screening, February 2002, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  323. An LC-MS Method for Analyzing Total Resveratrol in Grape Juice, Cranberry Juice, and in Wine

    Article • Journal of Agricultural and Food Chemistry, January 2002, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  324. Applications of pulsed ultrafiltration‐mass spectrometry

    Article • Mass Spectrometry Reviews, January 2002, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  325. Article • Pharmaceutical Research, January 2002, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  326. Soy Protein Isolate Prevents Chemically-Induced Rat Mammary Tumors

    Article • Pharmaceutical Biology, January 2002, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  327. Oxidative DNA Damage in Prostate Cancer Patients Consuming Tomato Sauce-Based Entrees as a Whole-Food Intervention

    Article • JNCI Journal of the National Cancer Institute, December 2001, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  328. Equine Estrogen Metabolite 4-Hydroxyequilenin Induces DNA Damage in the Rat Mammary Tissues:  Formation of Single-Strand Breaks, Apurinic Sites, Stable Adducts, and Oxidized Bases

    Article • Chemical Research in Toxicology, November 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  329. Synthesis and Reactivity of Potential Toxic Metabolites of Tamoxifen Analogues:  Droloxifene and Toremifene o-Quinones

    Article • Chemical Research in Toxicology, November 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  330. Determination of Folates in Human Plasma Using Hydrophilic Interaction Chromatography−Tandem Mass Spectrometry

    Article • Analytical Chemistry, October 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  331. Screening Botanical Extracts for Quinoid Metabolites

    Article • Chemical Research in Toxicology, October 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  332. Analysis and screening of combinatorial libraries using mass spectrometry

    Article • Biopharmaceutics & Drug Disposition, October 2001, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  333. Mass Spectrometry of Chlorophylls

    Article • Current Protocols in Food Analytical Chemistry, August 2001, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  334. Simultaneous determination of all‐trans, 9‐cis, 13‐cis retinoic acid and retinol in rat prostate using liquid chromatography–mass spectrometry

    Article • Journal of Mass Spectrometry, August 2001, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  335. Inactivation of monoamine oxidase B by 1-phenylcyclopropylamine

    Article • Bioorganic & Medicinal Chemistry Letters, July 2001, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  336. Inactivation of C30A Trimethylamine Dehydrogenase by N-Cyclopropyl-α-methylbenzylamine, 1-Phenylcyclopropylamine, and Phenylhydrazine

    Article • Biochemistry, June 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  337. Synthesis and Reactivity of the Catechol Metabolites from the Equine Estrogen, 8,9-Dehydroestrone

    Article • Chemical Research in Toxicology, May 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  338. Spectrometric Evidence for the Flavin−1-Phenylcyclopropylamine Inactivator Adduct with Monoamine Oxidase N

    Article • Biochemistry, April 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  339. Mass Spectrometry of Carotenoids

    Article • Current Protocols in Food Analytical Chemistry, April 2001, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  340. Analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors using liquid chromatography–electrospray mass spectrometry

    Article • Journal of Chromatography B Biomedical Sciences and Applications, April 2001, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  341. Evaluation of Estrogenic Activity of Plant Extracts for the Potential Treatment of Menopausal Symptoms

    Article • Journal of Agricultural and Food Chemistry, March 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  342. Structural and Functional Consequences of Inactivation of Human Glutathione S-Transferase P1-1 Mediated by the Catechol Metabolite of Equine Estrogens, 4-Hydroxyequilenin

    Article • Biochemistry, March 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  343. DNA Oxidation Induced by Cyclooxygenase-2

    Article • Chemical Research in Toxicology, March 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  344. Comparison of negative and positive ion electrospray tandem mass spectrometry for the liquid chromatography tandem mass spectrometry analysis of oxidized deoxynucleosides

    Article • Journal of the American Society for Mass Spectrometry, January 2001, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  345. Unconventional Origin of Metal Ion Rescue in the Hammerhead Ribozyme Reaction:  Mn2+-Assisted Redox Conversion of 2‘-Mercaptocytidine to Cytidine

    Article • Journal of the American Chemical Society, November 2000, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  346. Activity-Guided Isolation of Antioxidative Constituents ofCotinuscoggygria

    Article • Journal of Natural Products, October 2000, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  347. Use of High-Performance Liquid Chromatography−Tandem Mass Spectrometry To Distinguish Panax ginseng C. A. Meyer (Asian Ginseng) and Panax quinquefolius L. (North American Ginseng)

    Article • Analytical Chemistry, October 2000, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  348. Effects of Ozone and Oxygen on the Degradation of Carotenoids in an Aqueous Model System

    Article • Journal of Agricultural and Food Chemistry, September 2000, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  349. A Liquid Chromatography−Mass Spectrometry Method for the Quantification of Bioavailability and Bioconversion of β-Carotene to Retinol in Humans

    Article • Analytical Chemistry, August 2000, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  350. Evaluation of Cyclooxygenase-2 Inhibitors Using Pulsed Ultrafiltration Mass Spectrometry

    Article • Analytical Chemistry, July 2000, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  351. Vitamin A and Carotenoids

    Article • April 2000, Taylor & Francis

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  352. A Metabolite of Equine Estrogens, 4-Hydroxyequilenin, Induces DNA Damage and Apoptosis in Breast Cancer Cell Lines

    Article • Chemical Research in Toxicology, April 2000, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  353. Preface

    Article • Combinatorial Chemistry & High Throughput Screening, February 2000, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  354. Synthesis and Reactivity of a Potential Carcinogenic Metabolite of Tamoxifen:  3,4-Dihydroxytamoxifen-o-quinone

    Article • Chemical Research in Toxicology, December 1999, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  355. Solubilization and stabilization of carotenoids using micelles: Delivery of lycopene to cells in culture

    Article • Lipids, October 1999, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  356. Carotenoid Composition of Marigold (Tagetes erecta) Flower Extract Used as Nutritional Supplement

    Article • Journal of Agricultural and Food Chemistry, September 1999, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  357. Mechanism of Inactivation of γ-Aminobutyric Acid Aminotransferase by (S)-4-Amino-4,5-dihydro-2-thiophenecarboxylic Acid

    Article • Journal of the American Chemical Society, August 1999, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  358. Mechanistic Studies of the Inactivation of Inducible Nitric Oxide Synthase by N5-(1-Iminoethyl)-l-ornithine (l-NIO)

    Article • Journal of the American Chemical Society, January 1999, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  359. The Major Metabolite of Equilin, 4-Hydroxyequilin, Autoxidizes to an o-Quinone Which Isomerizes to the Potent Cytotoxin 4-Hydroxyequilenin-o-quinone

    Article • Chemical Research in Toxicology, January 1999, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  360. Flavonoid Constituents of Chorizanthe diffusa with Potential Cancer Chemopreventive Activity

    Article • Journal of Agricultural and Food Chemistry, December 1998, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  361. The Equine Estrogen Metabolite 4-Hydroxyequilenin Causes DNA Single-Strand Breaks and Oxidation of DNA Bases in Vitro

    Article • Chemical Research in Toxicology, August 1998, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  362. Analysis, pharmacokinetics and therapeutic drug monitoring of mycophenolic acid

    Article • Clinical Biochemistry, July 1998, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  363. Inhibition of Glutathione S-Transferase Activity by the Quinoid Metabolites of Equine Estrogens

    Article • Chemical Research in Toxicology, June 1998, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  364. Immobilized thymine chromatography–mass spectrometry of oligonucleotides

    Article • Journal of Chromatography A, May 1998, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  365. ChemInform Abstract: Liquid Chromatography/Mass Spectrometry of Carotenoids

    Article • ChemInform, January 1998, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  366. Alkylation of 2‘-Deoxynucleosides and DNA by the Premarin Metabolite 4-Hydroxyequilenin Semiquinone Radical

    Article • Chemical Research in Toxicology, January 1998, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  367. Development of a method for quantitation of retinol and retinyl palmitate in human serum using high-performance liquid chromatography–atmospheric pressure chemical ionization–mass spectrometry

    Article • Journal of Chromatography A, January 1998, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  368. Screening Solution-Phase Combinatorial Libraries Using Pulsed Ultrafiltration/Electrospray Mass Spectrometry

    Article • Journal of Medicinal Chemistry, December 1997, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  369. Mechanism of Inactivation of Neuronal Nitric Oxide Synthase by Nω-Allyl-l-Arginine

    Article • Journal of the American Chemical Society, November 1997, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  370. Reaction of the Premarin Metabolite 4-Hydroxyequilenin Semiquinone Radical with 2‘-Deoxyguanosine:  Formation of Unusual Cyclic Adducts

    Article • Journal of the American Chemical Society, November 1997, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  371. The reactivity of o-quinones which do not isomerize to quinone methides correlates with alkylcatechol-induced toxicity in human melanoma cells

    Article • Chemico-Biological Interactions, September 1997, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  372. Pulsed Ultrafiltration Mass Spectrometry:  A New Method for Screening Combinatorial Libraries

    Article • Analytical Chemistry, June 1997, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  373. Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity

    Article • Carcinogenesis, May 1997, Oxford University Press (OUP)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  374. Liquid chromatography/mass spectrometry of carotenoids

    Article • Pure and Applied Chemistry, January 1997, De Gruyter

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  375. Electrospray Liquid Chromatography/Mass Spectrometry of Ginsenosides

    Article • Analytical Chemistry, November 1995, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  376. Electrospray Liquid Chromatography-Mass Spectrometry of Carotenoids

    Article • Analytical Chemistry, July 1995, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  377. Fast atom bombardment tandem mass spectrometry of the anti‐parasitic agent pentamidine and its oxygenated metabolites

    Article • Journal of Mass Spectrometry, April 1995, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  378. Fast Atom Bombardment Tandem Mass Spectrometry of Carotenoids

    Article • Journal of Agricultural and Food Chemistry, February 1995, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  379. High‐performance liquid chromatography with light‐scattering detection and desorption chemical‐ionization tandem mass spectrometry of milk fat triacylglycerols

    Article • Lipids, January 1995, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  380. Mass spectrometry

    Article • January 1995, Springer Science + Business Media

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  381. Photolytic Dechlorination of 4-Chlorophenol Using an ArF* Excimer Laser.

    Article • Holzforschung, January 1995, De Gruyter

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  382. Oxidation of dicyclopentadiene in surface water

    Article • Biological Mass Spectrometry, October 1993, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  383. Continuous-flow fast-atom-bombardment liquid chromatography/mass spectrometry of carotenoids

    Article • Analytical Chemistry, April 1993, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  384. Tritiated diimide: a regio- and stereo-selective tritium-labelling reagent

    Article • Journal of the Chemical Society Chemical Communications, January 1993, Royal Society of Chemistry

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  385. Rates of peptide proteolysis measured using liquid chromatography and continuous-flow fast atom bombardment mass spectrometry

    Article • Analytical Chemistry, October 1992, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  386. Characterization of oligomers of 3,3,3-trifluoro-1-phenylpropyne and 1-phenylpropyne by mass spectrometry

    Article • Journal of Fluorine Chemistry, February 1992, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  387. [30] Fast-atom bombardment and continuous-flow fast-atom bombardment mass spectrometry in carotenoid analysis

    Article • January 1992, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  388. Continuous-flow fast atom bombardment and field desorption mass spectrometry of oligomers of 3,3,3-trifluoro-1-phenylpropyne

    Article • Analytical Chemistry, November 1991, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  389. Identification of chlorophyll derivatives by mass spectrometry

    Article • Journal of Agricultural and Food Chemistry, August 1991, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  390. Continuous-flow fast atom bombardment mass spectrometry of oligonucleotides

    Article • Journal of the American Society for Mass Spectrometry, April 1991, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  391. Characterization of cisplatin adducts of oligonucleotides by fast atom bombardment mass spectrometry

    Article • Analytical Biochemistry, February 1991, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  392. High-performance liquid chromatography—continuous-flow fast atom bombardment mass spectrometry of chlorophyll derivatives

    Article • Journal of Chromatography A, January 1991, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  393. Matrix selection for the analysis of hydrophilic dyes by fast atom bombardment mass spectrometry

    Article • Dyes and Pigments, January 1991, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  394. Identification of carrot inositol phospholipids by fats atom bombardment mass spectrometry

    Article • Lipids, June 1990, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  395. Formylated peptides from cyanogen bromide digests identified by fast atom bombardment mass spectrometry

    Article • Analytical Biochemistry, April 1990, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  396. Formation of negative ions of monosubstituted group VIB pentacarbonyls during fast atom bombardment mass spectrometry

    Article • Organic Mass Spectrometry, January 1990, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  397. Enhanced sensitivity of peptide analysis by fast‐atom bombardment mass spectrometry using nitrocellulose as a substrate

    Article • Rapid Communications in Mass Spectrometry, February 1989, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  398. Characterization of acyl-linked glucuronides by electron impact and fast atom bombardment mass spectrometry

    Article • Biological Mass Spectrometry, August 1988, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  399. Comparison of electron impact, desorption chemical ionization, field desorption, and fast atom bombardment mass spectra of nine monosubstituted Group VI metal carbonyls

    Article • Analytical Chemistry, July 1988, American Chemical Society (ACS)

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  400. Derivatives of dicyclopentadiene in ground water

    Article • Journal of Mass Spectrometry, March 1987, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  401. Reaction of bilirubin glucuronides with serum albumin

    Article • Journal of Chromatography B Biomedical Sciences and Applications, January 1986, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  402. Characterization of oxygen-linked glucuronides by laser desorption mass spectrometry

    Article • Journal of Mass Spectrometry, June 1984, Wiley

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  403. Time-resolved laser desorption mass spectrometry. I. Desorption of preformed ions

    Article • International Journal of Mass Spectrometry and Ion Physics, March 1983, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  404. Thermal, laser, and fast atom desorption

    Article • International Journal of Mass Spectrometry and Ion Physics, January 1983, Elsevier

    Professor of Pharmaceutical Sciences Richard B. van Breemen

  405. Preface

    Article • Combinatorial Chemistry & High Throughput Screening, January 1970, Bentham Science Publishers

    Professor of Pharmaceutical Sciences Richard B. van Breemen