All Stories

  1. Polypurine Reverse Hoogsteen hairpins as a therapeutic tool for SARS-CoV-2 infection
  2. Surface decoration of PLGA nanoparticles enables efficient transport of floxuridine oligomers into mammalian cells
  3. The synthesis of solid supports carrying base labile linkers to generate 3′-phosphate oligonucleotides
  4. Engineering ternary systems as non-viral vehicles for transporting floxuridine oligomer
  5. Biophysical evaluation of antiparallel triplexes for biosensing and biomedical applications
  6. Defined covalent attachment of three cancer drugs to DNA origami increases cytotoxicity at nanomolar concentration
  7. Single‐Step Functionalization Strategy of Graphene Microtransistor Array with Chemically Modified Aptamers for Biosensing Applications
  8. Synthesis and Evaluation of 3′-Oleyl–Oligonucleotide Conjugates as Potential Cellular Uptake Enhancers
  9. Synthesis of 2′-O-Methyl/2′-O-MOE-L-Nucleoside Derivatives and Their Applications: Preparation of G-Quadruplexes, Their Characterization, and Stability Studies
  10. Special Issue “Frontiers in Nucleic Acid Chemistry—In Memory of Professor Enrique Pedroso for His Outstanding Contributions to Nucleic Acid Chemistry”
  11. Rapid and Highly Efficient Separation of i-Motif DNA Species by CE-UV and Multivariate Curve Resolution
  12. Site-directed cysteine coupling of disulfide-containing non-antibody carrier proteins (THIOCAPs)
  13. Detection of pyrimidine-rich DNA sequences based on the formation of parallel and antiparallel triplex DNA and fluorescent silver nanoclusters
  14. Exploring the stabilizing effect on the i-motif of neighboring structural motifs and drugs
  15. Stability of polymeric cationic niosomes and their plasmid DNA-based complexes as gene delivery carriers
  16. Evaluation of Poly(N-Ethyl Pyrrolidine Methacrylamide) (EPA) and Derivatives as Polymeric Vehicles for miRNA Delivery to Neural Cells
  17. Oligonucleotides Carrying Nucleoside Antimetabolites as Potential Prodrugs
  18. Lipid and Peptide-Oligonucleotide Conjugates for Therapeutic Purposes: From Simple Hybrids to Complex Multifunctional Assemblies
  19. Correction: Clua et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules 2022, 27, 3944
  20. Detection of SARS-CoV-2 Virus by Triplex Enhanced Nucleic Acid Detection Assay (TENADA)
  21. Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region
  22. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes
  23. Cover Picture: Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications (Chem. Rec. 4/2022)
  24. A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model
  25. Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications
  26. Correlation between Biophysical Properties of Niosomes Elaborated with Chloroquine and Different Tensioactives and Their Transfection Efficiency
  27. Investigation of the Complexes Formed between PARP1 Inhibitors and PARP1 G-Quadruplex at the Gene Promoter Region
  28. Rational engineering of a human GFP-like protein scaffold for humanized targeted nanomedicines
  29. Biodistribution of 68/67Ga-Radiolabeled Sphingolipid Nanoemulsions by PET and SPECT Imaging
  30. Exploring the Interaction of Curaxin CBL0137 with G-Quadruplex DNA Oligomers
  31. The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis
  32. Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake
  33. Structural Effects of Incorporation of 2'‐Deoxy‐2'2'‐Difluorodeoxycytidine (Gemcitabine) in A‐ and B‐Form Duplexes
  34. Parallel G-quadruplex Structures Increase Cellular Uptake and Cytotoxicity of 5-Fluoro-2′-deoxyuridine Oligomers in 5-Fluorouracil Resistant Cells
  35. Biomedical Applications of DNA-nanostructures
  36. EcoRII Restriction Endonuclease Forms Specific Contacts to the Bases of Its Target Sequence Flipped from DNA in a Transition Complex with Photoactivatable Substrates
  37. G-quadruplex binding properties of a potent PARP-1 inhibitor derived from 7-azaindole-1-carboxamide
  38. Oligonucleotides Containing 1-Aminomethyl or 1-Mercaptomethyl-2-deoxy-d-ribofuranoses: Synthesis, Purification, Characterization, and Conjugation with Fluorophores and Lipids
  39. Nanoparticles for Brain Drug Delivery
  40. Nucleic Acids Chemistry
  41. Preparation of Lipid-Conjugated siRNA Oligonucleotides for Enhanced Gene Inhibition in Mammalian Cells
  42. Studies on the interactions of Ag(i) with DNA and their implication on the DNA-templated synthesis of silver nanoclusters and on the interaction with complementary DNA and RNA sequences
  43. Design and engineering of tumor-targeted, dual-acting cytotoxic nanoparticles
  44. Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery
  45. Developing Protein–Antitumoral Drug Nanoconjugates as Bifunctional Antimicrobial Agents
  46. Triplex Hybridization-Based Nanosystem for the Rapid Screening of Pneumocystis Pneumonia in Clinical Samples
  47. Study of alkaloid berberine and its interaction with the human telomeric i-motif DNA structure
  48. Sorting hidden patterns in nanoparticle performance for glioblastoma using machine learning algorithms
  49. Non-viral mediated gene therapy in human cystic fibrosis airway epithelial cells recovers chloride channel functionality
  50. Influence of pH and a porphyrin ligand on the stability of a G-quadruplex structure within a duplex segment near the promoter region of the SMARCA4 gene
  51. Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins
  52. Fast and Accurate Pneumocystis Pneumonia Diagnosis in Human Samples Using a Label-Free Plasmonic Biosensor
  53. Brain Angiogenesis Induced by Nonviral Gene Therapy with Potential Therapeutic Benefits for Central Nervous System Diseases
  54. Niosome-Based Approach for In Situ Gene Delivery to Retina and Brain Cortex as Immune-Privileged Tissues
  55. Ethylcellulose nanoparticles as a new “in vitro” transfection tool for antisense oligonucleotide delivery
  56. Sulfonamide as amide isostere for fine-tuning the gelation properties of physical gels
  57. Liposomes‐ in ‐Chitosan Hydrogels: Challenges and Opportunities for Biomedical Applications
  58. Alginate Hydrogels as Scaffolds and Delivery Systems to Repair the Damaged Spinal Cord
  59. A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor
  60. Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41
  61. Aptamer-peptide conjugates as a new strategy to modulate human α-thrombin binding affinity
  62. Cationic niosome-based hBMP7 gene transfection of neuronal precursor NT2 cells to reduce the migration of glioma cells in vitro
  63. Study of conformational transitions of i-motif DNA using time-resolved fluorescence and multivariate analysis methods
  64. Gene delivery to the rat retina by non-viral vectors based on chloroquine-containing cationic niosomes
  65. The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry
  66. Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
  67. On the Race for More Stretchable and Tough Hydrogels
  68. Parallel Clamps and Polypurine Hairpins (PPRH) for Gene Silencing and Triplex‐Affinity Capture: Design, Synthesis, and Use
  69. Efficient bioactive oligonucleotide‐protein conjugation for cell‐targeted cancer therapy
  70. Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery
  71. Expanding the limits of amide–triazole isosteric substitution in bisamide-based physical gels
  72. Overview of DNA Self-Assembling: Progresses in Biomedical Applications
  73. Detection of a microRNA involved in human disease
  74. Detection of DNA methylation
  75. Gene transfer to rat cerebral cortex mediated by polysorbate 80 and poloxamer 188 nonionic surfactant vesicles
  76. Synthesis of Oligonucleotides Carrying Nucleic Acid Derivatives of Biomedical and Structural Interest
  77. Successful evaluation of a nanodrug against metastasis
  78. Preparation of new compounds with interesting porperties in biomedicine
  79. siRNA Modified with 2′-Deoxy-2′-C -methylpyrimidine Nucleosides
  80. Evaluation of the effect of polymorphism on G-quadruplex-ligand interaction by means of spectroscopic and chromatographic techniques
  81. Synthesis, Characterization, and Self-Assembly of a Tetrathiafulvalene (TTF)–Triglycyl Derivative
  82. Isosteric Substitution of 4H-1,2,4-Triazole by 1H-1,2,3-Triazole in Isophthalic Derivative Enabled Hydrogel Formation for Controlled Drug Delivery
  83. Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates
  84. Stem cell-based gene delivery mediated by cationic niosomes for bone regeneration
  85. Exploring PAZ/3′-overhang interaction to improve siRNA specificity. A combined experimental and modeling study
  86. DNA-based nanoscaffolds as vehicles for 5-fluoro-2′-deoxyuridine oligomers in colorectal cancer therapy
  87. Electrochemical and AFM Characterization of G-Quadruplex Electrochemical Biosensors and Applications
  88. Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies
  89. Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes
  90. Study of light-induced formation of photodimers in the i-motif nucleic acid structure by rapid-scan FTIR difference spectroscopy and hybrid hard- and soft-modelling
  91. AS1411-decorated niosomes as effective nanocarriers for Ru(iii)-based drugs in anticancer strategies
  92. Lipid-Oligonucleotide Conjugates Forming G-Quadruplexes (Lipoquads) as Potent Inhibitors of HIV Entry
  93. i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene
  94. DNA-Origami-Aided Lithography for Sub-10 Nanometer Pattern Printing
  95. Biochemistry of RNA Silencing
  96. Cover Picture: Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues (ChemBioChem 12/2017)
  97. Transfection of Antisense Oligonucleotides Mediated by Cationic Vesicles Based on Non-Ionic Surfactant and Polycations Bearing Quaternary Ammonium Moieties
  98. Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues
  99. The effect of l -thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures
  100. Erratum: Corrigendum: The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein
  101. Antiviral activity of lipid-DNA molecules
  102. DNA-Origami-Driven Lithography for Patterning on Gold Surfaces with Sub-10 nm Resolution
  103. Boronic acid-modified alginate enables direct formation of injectable, self-healing and multistimuli-responsive hydrogels
  104. Cationic nioplexes-in-polysaccharide-based hydrogels as versatile biodegradable hybrid materials to deliver nucleic acids
  105. Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms
  106. The impact of an extended nucleobase-2′-deoxyribose linker in the biophysical and biological properties of oligonucleotides
  107. Meet Our Editorial Board Member
  108. Controlling the Reversible Assembly of Liposomes through a Multistimuli Responsive Anchored DNA
  109. Glucose-Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA
  110. The role of helper lipids in the intracellular disposition and transfection efficiency of niosome formulations for gene delivery to retinal pigment epithelial cells
  111. The Effect of Small Cosolutes that Mimic Molecular Crowding Conditions on the Stability of Triplexes Involving Duplex DNA
  112. siRNA and RNAi optimization
  113. The influence of the polar head-group of synthetic cationic lipids on the transfection efficiency mediated by niosomes in rat retina and brain
  114. Biodegradable liposome-encapsulated hydrogels for biomedical applications: a marriage of convenience
  115. Cellular uptake studies of antisense oligonucleotides using G-quadruplex-nanostructures. The effect of cationic residue on the biophysical and biological properties
  116. Nioplexes encapsulated in supramolecular hybrid biohydrogels as versatile delivery platforms for nucleic acids
  117. Understanding the effect of the nature of the nucleobase in the loops on the stability of the i-motif structure
  118. Label-free electrochemical DNA sensor using “click”-functionalized PEDOT electrodes
  119. Sensitive and label-free detection of miRNA-145 by triplex formation
  120. Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers
  121. 1-[2,3-Bis(tetradecyloxy)propyl]-3-[2-(piperazin-1-yl)ethyl]urea
  122. New Insights into Gene Delivery to Human Neuronal Precursor NT2 Cells: A Comparative Study between Lipoplexes, Nioplexes, and Polyplexes
  123. Synthesis of oligonucleotides carrying fluorescently labelled O6-alkylguanine for measuring hAGT activity
  124. RNA modified with acyclic threoninol nucleic acids for RNA interference
  125. Protamine/DNA/Niosome Ternary Nonviral Vectors for Gene Delivery to the Retina: The Role of Protamine
  126. Atomic Force Microscopy and Voltammetric Investigation of Quadruplex Formation between a Triazole-Acridine Conjugate and Guanine-Containing Repeat DNA Sequences
  127. Modulation of the RNA Interference Activity Using Central Mismatched siRNAs and Acyclic Threoninol Nucleic Acids (aTNA) Units
  128. Glucose Conjugation of Anti-HIV-1 Oligonucleotides Containing Unmethylated CpG Motifs Reduces Their Immunostimulatory Activity
  129. Niosomes based on synthetic cationic lipids for gene delivery: the influence of polar head-groups on the transfection efficiency in HEK-293, ARPE-19 and MSC-D1 cells
  130. Novel non-viral gene delivery systems composed of carbosilane dendron functionalized nanoparticles prepared from nano-emulsions as non-viral carriers for antisense oligonucleotides
  131. The effect of a cytidine derivative on the stability of intramolecular i-motifs was investigated.
  132. RNA/aTNA Chimeras: RNAi Effects and Nucleases Resistance of Single and Double Stranded RNAs
  133. Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles
  134. Cationic vesicles based on non-ionic surfactant and synthetic aminolipids mediate delivery of antisense oligonucleotides into mammalian cells
  135. DNA Nanoarchitectures: Steps towards Biological Applications
  136. Quadruplex Nanostructures of d(TGGGGT): Influence of Sodium and Potassium Ions
  137. Oligonucleotide delivery: a patent review (2010 – 2013)
  138. Effects of Sugar Functional Groups, Hydrophobicity, and Fluorination on Carbohydrate–DNA Stacking Interactions in Water
  139. Direct Covalent Attachment of DNA Microarrays by Rapid Thiol–Ene “Click” Chemistry
  140. A Novel Formulation Based on 2,3-Di(tetradecyloxy)propan-1-amine Cationic Lipid Combined with Polysorbate 80 for Efficient Gene Delivery to the Retina
  141. to fold or to dimerize a dilema for modified TBA
  142. Fundamental aspects of the nucleic acid i-motif structures
  143. A novel cationic niosome formulation for gene delivery to the retina
  144. Challenges and Opportunities for Oligonucleotide-Based Therapeutics by Antisense and RNA Interference Mechanisms
  145. Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops
  146. Double-tailed lipid modification as a promising candidate for oligonucleotide delivery in mammalian cells
  147. Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates
  148. DNA Origami as a DNA Repair Nanosensor at the Single-Molecule Level
  149. Electrostatic Binding and Hydrophobic Collapse of Peptide–Nucleic Acid Aggregates Quantified Using Force Spectroscopy
  150. Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
  151. Efficient Self-Assembly in Water of Long Noncovalent Polymers by Nucleobase Analogues
  152. Functionalization of the 3′-Ends of DNA and RNA Strands with N-ethyl-N-coupled Nucleosides: A Promising Approach To Avoid 3′-Exonuclease-Catalyzed Hydrolysis of Therapeutic Oligonucleotides
  153. Carbohydrate-DNA Interactions at G-Quadruplexes: Folding and Stability Changes by Attaching Sugars at the 5′-End
  154. The detection of a protein involved in coagulation using fluorescence
  155. Self-assembled G-quadruplex nanostructures: AFM and voltammetric characterization
  156. Biophysical and RNA Interference Inhibitory Properties of Oligonucleotides Carrying Tetrathiafulvalene Groups at Terminal Positions
  157. 20 Supramolecular polymerization of nucleobase-like monomers in water
  158. Porphyrin binding mechanism is altered by protonation at the loops in G-quadruplex DNA formed near the transcriptional activation site of the human c-kit gene
  159. Oligonucleotide-Peptide Conjugates: Solid-Phase Synthesis under Acidic Conditions and Use in ELISA Assays
  160. Synthesis of Steroid–Oligonucleotide Conjugates for a DNA Site-Encoded SPR Immunosensor
  161. Receptor-Based Virtual Screening and Biological Characterization of Human Apurinic/Apyrimidinic Endonuclease (Ape1) Inhibitors
  162. Synthesis of Oligonucleotides Carrying Thiol Groups Using a Simple Reagent Derived from Threoninol
  163. Development of an impedimetric DNA-biosensor based on layered double hydroxide for the detection of long ssDNA sequences
  164. The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer
  165. Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives
  166. Impact of Methylation on the Physical Properties of DNA
  167. Structure of Triplex DNA in the Gas Phase
  168. Synthesis and Structural Characterization of Stable Branched DNA G-Quadruplexes Using the Trebler Phosphoramidite
  169. Synthesis and in vitro inhibition properties of oligonucleotide conjugates carrying amphipathic proline-rich peptide derivatives of the sweet arrow peptide (SAP)
  170. Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications
  171. Synthesis and in vitro Inhibition Properties of siRNA Conjugates Carrying Acridine and Quindoline Moieties
  172. Functionally Enhanced siRNA Targeting TNFα Attenuates DSS-induced Colitis and TLR-mediated Immunostimulation in Mice
  173. Facile Modification of Silica Substrates Provides a Platform for Direct‐Writing Surface Click Chemistry
  174. Sensitive and label-free biosensing of RNA with predicted secondary structures by a triplex affinity capture method
  175. Apolar carbohydrates as DNA capping agents
  176. Interstrand interactions on DNA duplexes modified by TTF units at the 3′ or 5′-ends
  177. Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5′-(C3TA2)4-3′ sequence of the human telomere
  178. Use of Oligonucleotides Carrying Photolabile Groups for the Control of the Deposition of Nanoparticles in Surfaces and Nanoparticle Association
  179. Functionalization of Surfaces with Synthetic Oligonucleotides
  180. Functionalization and Self-Assembly of DNA Bidimensional Arrays
  181. Acridine and quindoline oligomers linked through a 4-aminoproline backbone prefer G-quadruplex structures
  182. A Direct, Efficient Method for the Preparation of siRNAs Containing Ribo-likeNorthBicyclo[3.1.0]hexane Pseudosugars
  183. Synthesis and Properties of Oligodeoxynucleotides Carrying 2-Aminopurine
  184. Evaluation of the structure–activity relationship of thrombin with thrombin binding aptamers by voltammetry and atomic force microscopy
  185. Effect of North Bicyclo[3.1.0]hexane 2′-Deoxy-pseudosugars on RNA Interference: A Novel Class of siRNA Modification
  186. Highly Polar Carbohydrates Stack onto DNA Duplexes via CH/π Interactions
  187. Synthesis of Lipid-Oligonucleotide Conjugates for RNA Interference Studies
  188. Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations
  189. Branched RNA: A New Architecture for RNA Interference
  190. Synthesis of Oligonucleotide–Peptide Conjugates for Biomedical and Technological Applications
  191. Synthesis and properties of small interfering RNA duplexes carrying 5-ethyluridine residues
  192. Synthesis and structural properties of oligonucleotides covalently linked to acridine and quindoline derivatives through a threoninol linker
  193. Chemical equilibria studies using multivariate analysis methods
  194. Synthesis of Oligonucleotides Carrying Amino Lipid Groups at the 3′-End for RNA Interference Studies
  195. Synthesis and Properties of Oligonucleotides Carrying Isoquinoline Imidazo[1,2-a]azine Fluorescent Units
  196. Solid-Phase Synthesis of Oligodeoxynucleotides Containing N4-[2-(t-butyldisulfanyl)ethyl]-5-methylcytosine Moieties
  197. Synthesis, Cell-Surface Binding, and Cellular Uptake of Fluorescently Labeled Glucose−DNA Conjugates with Different Carbohydrate Presentation
  198. Stepwise synthesis of oligonucleotide–peptide conjugates containing guanidinium and lipophilic groups in their 3′-termini
  199. Spectrometric study of the oligodeoxyribonucleotide protonation in aqueous solution
  200. Fabrication of patterned surfaces by photolithographic exposure of DNA hairpins carrying a novel photolabile group
  201. Triplex-Stabilizing Properties of Parallel Clamps Carrying LNA Derivatives at theHoogsteenStrand
  202. Modified siRNAs for the study of the PAZ domain
  203. Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection ofO6-Alkylguanine-DNA Alkyltransferase Activity
  204. G-Quadruplex Nucleic Acids
  205. Structural Properties of G,T-Parallel Duplexes
  206. Synthesis and G-Quadruplex-Binding Properties of Defined Acridine Oligomers
  207. Thrombin-Binding Aptamer Quadruplex Formation: AFM and Voltammetric Characterization
  208. pH-Modulated Watson–Crick Duplex–Quadruplex Equilibria of Guanine-Rich and Cytosine-Rich DNA Sequences 140 Base Pairs Upstream of thec-kitTranscription Initiation Site
  209. Modified Oligonucleotides for Biosensing Applications
  210. Unique Tautomeric and Recognition Properties of Thioketothymines?
  211. DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site
  212. α,γ-Peptide Nanotube Templating of One-Dimensional Parallel Fullerene Arrangements
  213. Assembly of Two-Dimensional DNA Crystals CarryingN4-[2-(tert-Butyldisulfanyl)ethyl]cytosine Residues
  214. Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamer
  215. Targeting the G-quadruplex-forming region near the P1 promoter in the human BCL-2 gene with the cationic porphyrin TMPyP4 and with the complementary C-rich strand
  216. Fluorescence site-encoded DNA addressable hapten microarray for anabolic androgenic steroids
  217. Classification of nucleic acids structures by means of the chemometric analysis of circular dichroism spectra
  218. Photocleavage of Peptides and Oligodeoxynucleotides Carrying 2-Nitrobenzyl Groups
  219. Stepwise synthesis of RNA conjugates carrying peptide sequences for RNA interference studies
  220. Synthesis and Hybridization Properties of Modified Oligodeoxynucleotides Carrying Non-Natural Bases
  221. Amino-acids condensations in the preparation of Nα-9-fluorenylrnethyloxycarbonylamino-acids with 9-fluorenylmethylchloroformate
  222. Experimental Measurement of Carbohydrate-Aromatic Stacking in Water by Using a Dangling-Ended DNA Model System
  223. Study of the interaction between the G-quadruplex-forming thrombin-binding aptamer and the porphyrin 5,10,15,20-tetrakis-(N-methyl-4-pyridyl)-21,23H-porphyrin tetratosylate
  224. Design, synthesis and antiproliferative properties of oligomers with chromophore units linked by amide backbones
  225. Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones
  226. Incorporation of Zebularine from its 2′-Deoxyribonucleoside Triphosphate Derivative and Activity as a Template-Coding Nucleobase
  227. 8-Amino guanine accelerates tetramolecular G-quadruplex formation
  228. Synthesis of Oligonucleotide Derivatives Using ChemMatrix Supports
  229. Solution equilibria of the i-motif-forming region upstream of the B-cell lymphoma-2 P1 promoter
  230. Synthesis of Oligonucleotides Carrying 5′-5′ Linkages Using Copper-Catalyzed Cycloaddition Reactions
  231. A Flexible Method for the Fabrication of Gold Nanostructures Using Oligonucleotide Derivatives
  232. New developments in the synthesis of oligonucleotide-peptide conjugates
  233. Triplex Formation Using Oligonucleotide Clamps Carrying 8-Aminopurines
  234. ds-Oligonucleotide–Peptide Conjugates Featuring Peptides from the Leucine-Zipper Region of Fos as Switchable Receptors for the Oncoprotein Jun
  235. Analysis of Interaction between Dendriplexes and Bovine Serum Albumin
  236. Water-Soluble Carbosilane Dendrimers: Synthesis Biocompatibility and Complexation with Oligonucleotides; Evaluation for Medical Applications
  237. Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins
  238. First Characterization of a Biosensor for Large DNA Molecules using Quartz Crystal Microbalance and Impedance Spectroscopy
  239. Solid-Phase Synthesis of Modified Oligonucleotides
  240. Spectroscopic study of the interaction of actinomycin D with oligonucleotides carrying the central base sequences -XGCY- and -XGGCCY- using multivariate methods
  241. Erratum
  242. Trimethylguanosine Nucleoside Inhibits Cross-Linking Between Snurportin 1 and m3G-CAPPED U1 snRNA
  243. Efficient Sequence-Specific Purification of Listeria innocua mRNA Species by Triplex Affinity Capture with Parallel Tail-Clamps
  244. Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand
  245. DNA-templated assembly of nanoscale architectures for next-generation electronic devices
  246. Strand Displacement of Double-Stranded DNA by Triplex-Forming Antiparallel Purine-Hairpins
  247. Destabilization of Quadruplex DNA by 8-Aminoguanine
  248. Magnetically Trigged Direct Electrochemical Detection of DNA Hybridization Using Au67Quantum Dot as Electrical Tracer
  249. Toward an ICPMS-Linked DNA Assay Based on Gold Nanoparticles Immunoconnected through Peptide Sequences
  250. A Straightforward Synthesis of 5‘-Peptide Oligonucleotide Conjugates UsingNα-Fmoc-Protected Amino Acids
  251. DNA-templated assembly of nanoscale architectures
  252. “Parallel” and “Antiparallel Tail-Clamps” Increase the Efficiency of Triplex Formation with Structured DNA and RNA Targets
  253. Synthesis and Triplex-Forming Properties of Cyclic Oligonucleotides with (G,A)-Antiparallel Strands
  254. Hybridization and Melting Behavior of Peptide Nucleic Acid (PNA) Oligonucleotide Chimeras Conjugated to Gold Nanoparticles
  255. DNA-Templated Assembly of a Protein-Functionalized Nanogap Electrode
  256. Synthesis of OligonucleotidePeptide Conjugates Carrying the c-myc Peptide Epitope as Recognition System
  257. Synthesis and Triple-Helix-Stabilization Properties of Branched Oligonucleotides Carrying 8-Aminoadenine Moieties
  258. Synthesis and Properties of Oligonucleotides Carrying Cryptolepine Derivatives
  259. Synthesis of Oligoribonucleotides Containing 4‐Thiouridine Using the Convertible Nucleoside Approach and the 1‐(2‐Fluorophenyl)‐4‐Methoxypiperidin‐4‐yl Group
  260. Transgenic Rice Plants Expressing the Antifungal AFP Protein from Aspergillus Giganteus Show Enhanced Resistance to the Rice Blast Fungus Magnaporthe Grisea
  261. Antiparallel Triple Helices. Structural Characteristics and Stabilization by 8-Amino Derivatives
  262. Potent Inhibition ofHhaI DNA Methylase by the Aglycon of 2-(1H)-Pyrimidinone Riboside (Zebularine) at the GCGC Recognition Domain
  263. Properties of Triple Helices Formed by Oligonucleotides Containing 8-Aminopurines
  264. Synthesis of Branched Oligonucleotides as Templates for the Assembly of Nanomaterials
  265. Convenient Synthesis of 8-Amino-2′-deoxyadenosine
  266. Peptide–PNA Conjugates: Targeted Transport of Antisense Therapeutics into Tumors
  267. Imaging the DNA and nanoparticle components of a self-assembled nanoscale architecture
  268. Synthesis of labelled PNA oligomers by a post-synthetic modification approach
  269. Synthesis, stability, and protonation studies of a self-complementary dodecamer containing the modified nucleoside 2?-deoxyzebularine
  270. DNA-Controlled Assembly of Protein-Modified Gold Nanocrystals
  271. Synthesis and properties of radiolabeled CPTA-oligonucleotides
  272. Nanotechnology: Carbon nanotubes with DNA recognition
  273. DNA triple helices and biomedicine
  274. Biofunctionalization of Silica-Coated CdTe and Gold Nanocrystals
  275. Inhibition of HhaI DNA (Cytosine-C5) Methyltransferase by Oligodeoxyribonucleotides Containing 5-Aza-2′-deoxycytidine: Examination of the Intertwined Roles of Co-factor, Target, Transition State Structure and Enzyme Conformation
  276. Additional Binding Sites for Anionic Phospholipids and Calcium Ions in the Crystal Structures of Complexes of the C2 Domain of Protein Kinase Cα
  277. Iodouracil-mediated photocrosslinking of DNA to EcoRII restriction endonuclease in catalytic conditions
  278. Hoogsteen-Based Parallel-Stranded Duplexes of DNA. Effect of 8-Amino-purine Derivatives
  279. Plasmid transcriptional repressor CopG oligomerises to render helical superstructures unbound and in complexes with oligonucleotides
  280. Parallel-stranded hairpins containing 8-aminopurines. novel efficient probes for triple-helix formation
  281. SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES CONTAINING 8-BROMO-2′-DEOXYGUANOSINE
  282. AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES
  283. Preparation and Evaluation of Tumor-Targeting Peptide−Oligonucleotide Conjugates
  284. Synthesis and Hybridization Properties of DNA–PNA Chimeras Carrying 5-Bromouracil and 5-Methylcytosine
  285. Intracellular distribution of digoxigenin-labeled phosphorothioate oligonucleotides
  286. Synthesis and Binding Properties of Oligonucleotides Carrying Nuclear Localization Sequences
  287. “Action-at-a-Distance” Mutagenesis
  288. Theoretical calculations, synthesis and base pairing properties of oligonucleotides containing 8-amino-2'-deoxyadenosine
  289. The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator
  290. Synthesis of Oligodeoxynucleotides ContainingN4-Mercaptoethylcytosine and Their Use in the Preparation of Oligonucleotide−Peptide Conjugates Carrying c-mycTag-Sequence
  291. Triple helix stabilization properties of oligonucleotides containing 8-amino-2′-deoxyguanosine
  292. Biochemical basis of SOS-induced mutagenesis in Escherichia coli : Reconstitution of in vitro lesion bypass dependent on the UmuD′ 2 C mutagenic complex an...
  293. Exonuclease−Polymerase Active Site Partitioning of Primer−Template DNA Strands and Equilibrium Mg2+Binding Properties of Bacteriophage T4 DNA Polymerase†
  294. A Second-Step Splicing Activity Is Conserved from Yeast to Human
  295. 2′-O-Propargyl oligoribonucleotides: Synthesis and hybridisation
  296. Tandem 5′-GA:GA-3′ mismatches account for the high stability of the fold-back structures formed by the centromeric Drosophila dodeca-satellite 1 1Edited by I. Tinoco
  297. Preparation and Properties of Oligodeoxynucleotides Containing 5-Iodouracil and 5-Bromo- and 5-Iodocytosine
  298. Solid-phase synthesis of branched RNA and branched DNA/RNA chimeras
  299. Initiation of replication of plasmid pMV158: mechanisms of DNA strand-transfer reactions mediated by the initiator RepB protein
  300. A simple method for the synthesis of 2′-O-alkylguanosine derivatives
  301. Abasic Translesion Synthesis by DNA Polymerase β Violates the “A-rule”
  302. New carbamate supports for the preparation of 3′-amino-modified oligonucleotides
  303. Synthesis of 1,2-diacyl-sn-glycerophosphadidylserine from egg phosphatidylcholine by phosphoramidite Methodology
  304. NMR Study of the Conformation of the 2-Aminopurine:Cytosine Mismatch in DNA†
  305. Spectroscopic and Calorimetric Characterizations of DNA Duplexes Containing 2-Aminopurine†
  306. Divalent Zinc Cations Induce the Formation of Two Distinct Homoduplexes of a d(GA)20 DNA Sequence
  307. Preparation and properties of oligodeoxynucleotides containing 4-O-butylthymine, 2-fluorohypoxanthine and 5-azacytosine1
  308. Preparation of oligonucleotide-dexamethasone conjugates
  309. Preparation of Oligonucleotides Containing Non-natural Base Analogues
  310. Dam methylase fromEscherichia coli: kinetic studies using modified DNA oligomers: hemimethylated substrates
  311. Digoxigenin-Labeled Phosphorothioate Oligonucleotides: A New Tool for the Study of Cellular Uptake
  312. Synthesis and properties of oligonucleotides containing the mutagenic base O4-benzylthymidine
  313. Use of NPE-Protecting Groups for the Preparation of Oligonucleotides Without Using Nucleophiles During the Final Deprotection
  314. Use of oligonucleotide-alkaline phosphatase conjugates as non-radioactive probes for rapid analysis of a proteinase inhibitor gene fromZea mays
  315. Nucleotide Insertion and Primer Extension at Abasic Template Sites in Different Sequence Contexts
  316. Pre-Steady-State Kinetic Analysis of Sequence-Dependent Nucleotide Excision by the 3'-Exonuclease Activity of Bacteriophage T4 DNA Polymerase
  317. Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258
  318. Chemical synthesis of a fully active transcriptional repressor protein.
  319. Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids
  320. Synthesis of Oligodeoxyribonucleotides Containing 2,6-Diaminopurine
  321. Criteria for the economic large scale solid-phase synthesis of oligonucleotides
  322. Solid-phase N-glycopeptide synthesis using allyl side-chain protected Fmoc-amino acids
  323. A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides
  324. Gel-phase 31P-NMR. A new analytical tool to evaluate solid phase oligonucleoside synthesis.
  325. Both O4-methylthymine and O4-ethylthymine preferentially form alkyl T.G pairs that do not block in vitro replication in a defined sequence
  326. Detection of hepatitis B virus DNA in human serumsamples: Use of digoxigenin-labeled oligonucleotides as modified primers for the polymerase chain reaction
  327. -2-(2,4-dinitrophenyl)ethyloxycarbonyl-amino acids, new base labile protected derivatives suitable for solid-phase peptide synthesis.
  328. S-2-(2,4-dinitrophenyl)ethyl--cysteine: a new derivative for solid-phase peptide synthesis
  329. A synthetic procedure for the preparation of oligonucleotides without using ammonia and its application for the synthesis of oligonucleotides containing 0-4-alkyl thymidines.
  330. Preparation of oligonucleotides containing dAICA using an unexpected side-reaction observed on a protected derivative of 2-aza-2′-deoxyinosine.
  331. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides II. Synthesis of protected peptides
  332. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides I : Synthesis of the supports and their application to oligonucleotide synthesis.
  333. Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal sequence.
  334. Syhthesis of Oligonucleotides Containing 4-0-Ethylthymidine
  335. O-aryl phosphoramidites: synthesis, reactivity and evaluation of their use for solid-phase synthesis of oligonucleotides
  336. Synthesis and characterization of oligodeoxynucleotides containing the mutagenic base analogue 4-O-ethylthymine
  337. Characterization of the high pH wobble structure of the 2-aminopurine·cytosine mismatch by N-15 NMR spectroscopy
  338. Ionized and wobble base-pairing for bromouracil-guanine in equilibrium under physiological conditions
  339. Structural and Dynamic Properties of a Bromouracil-Adenine Base Pair in DNA Studied by Proton NMR
  340. NMR studies of the stable mismatch purine-thymine in the self-complementary d(CGPuAATTTCG) duplex in solution
  341. NMR studies on an oligodeoxynucleotide containing 2-aminopurine opposite adenine
  342. Synthesis of Oligonucleotides Containing the Abasic Site Model Compound 1,4-Anhydro-2-Deoxy-D-Ribitol
  343. An abasic site in DNA. Solution conformation determined by proton NMR and molecular mechanics calculations
  344. On the use of s-t-butylsulphenyl group for protection of cysteine in solid-phase peptide synthesis using fmoc-amino acids
  345. Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR.
  346. Convergent solid phase peptide synthesis-III
  347. Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine
  348. Synthesis and properties of oligonucleotides containing 2′-deoxynebularine and 2′-deoxyxanthosine
  349. Diketopiperazine formation in acetamido-and nitrobenzamido-bridgedpolymeric supports.