All Stories

  1. Conjugation strategy shapes antitumor efficacy and enables dose-sparing in non-antibody protein nanoconjugates
  2. Enhanced i‐Motif Stability through Consecutive 2′,2′‐Difluorocytidine Incorporation
  3. The Effect of 2′F-RNA on I-Motif Structure and Stability
  4. Resolution of complex mixtures of duplex and antiparallel triplex DNA structures by capillary electrophoresis and multivariate analysis
  5. Unraveling the Amplification-Free Quantitative Detection of Viral RNA in Nasopharyngeal Swab Samples Using a Compact Electrochemical Rapid Test Device
  6. Modified Bis-pyrimidine Clamps for Triplex Formation and Their Use in SARS-CoV-2 Detection
  7. Targeted Tumor Microenvironment Delivery of Floxuridine Prodrug via Soluble Silica Nanoparticles in Malignant Melanoma as a Model for Aggressive Cancer Treatment
  8. On the interaction of anticancer G-quadruplex ligands with GalNAc-functionalized G-quadruplex-forming carriers for selective recognition and treatment of hepatocellular carcinoma
  9. Targeted Tumor Microenvironment Delivery of Floxuridine ProdrugviaSoluble Silica Nanoparticles in Malignant Melanoma as a Model for Aggressive Cancer Treatment
  10. Assessment of methodologies based on the formation of antiparallel triplex DNA structures and fluorescent silver nanoclusters for the detection of pyrimidine-rich sequences
  11. Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism
  12. Manual and automated synthesis of modified oligonucleotides on core–shell solid supports
  13. Aptamer-Hytac Chimeras for Targeted Degradation of SARS-CoV-2 Spike-1
  14. Polypurine Reverse Hoogsteen hairpins as a therapeutic tool for SARS-CoV-2 infection
  15. Surface decoration of PLGA nanoparticles enables efficient transport of floxuridine oligomers into mammalian cells
  16. The synthesis of solid supports carrying base labile linkers to generate 3′-phosphate oligonucleotides
  17. DNA-directed immobilization fluorescent immunoarray for multiplexed antibiotic residue determination in milk
  18. Engineering ternary systems as non-viral vehicles for transporting floxuridine oligomer
  19. Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives
  20. Biophysical evaluation of antiparallel triplexes for biosensing and biomedical applications
  21. Defined covalent attachment of three cancer drugs to DNA origami increases cytotoxicity at nanomolar concentration
  22. Single‐Step Functionalization Strategy of Graphene Microtransistor Array with Chemically Modified Aptamers for Biosensing Applications
  23. Synthesis and Evaluation of 3′-Oleyl–Oligonucleotide Conjugates as Potential Cellular Uptake Enhancers
  24. Synthesis of 2′-O-Methyl/2′-O-MOE-L-Nucleoside Derivatives and Their Applications: Preparation of G-Quadruplexes, Their Characterization, and Stability Studies
  25. Special Issue “Frontiers in Nucleic Acid Chemistry—In Memory of Professor Enrique Pedroso for His Outstanding Contributions to Nucleic Acid Chemistry”
  26. Rapid and Highly Efficient Separation of i-Motif DNA Species by CE-UV and Multivariate Curve Resolution
  27. Site-directed cysteine coupling of disulfide-containing non-antibody carrier proteins (THIOCAPs)
  28. Detection of pyrimidine-rich DNA sequences based on the formation of parallel and antiparallel triplex DNA and fluorescent silver nanoclusters
  29. Exploring the stabilizing effect on the i-motif of neighboring structural motifs and drugs
  30. Stability of polymeric cationic niosomes and their plasmid DNA-based complexes as gene delivery carriers
  31. Evaluation of Poly(N-Ethyl Pyrrolidine Methacrylamide) (EPA) and Derivatives as Polymeric Vehicles for miRNA Delivery to Neural Cells
  32. Oligonucleotides Carrying Nucleoside Antimetabolites as Potential Prodrugs
  33. Lipid and Peptide-Oligonucleotide Conjugates for Therapeutic Purposes: From Simple Hybrids to Complex Multifunctional Assemblies
  34. Correction: Clua et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules 2022, 27, 3944
  35. Detection of SARS-CoV-2 Virus by Triplex Enhanced Nucleic Acid Detection Assay (TENADA)
  36. Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region
  37. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes
  38. Cover Picture: Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications (Chem. Rec. 4/2022)
  39. A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model
  40. Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications
  41. Correlation between Biophysical Properties of Niosomes Elaborated with Chloroquine and Different Tensioactives and Their Transfection Efficiency
  42. Investigation of the Complexes Formed between PARP1 Inhibitors and PARP1 G-Quadruplex at the Gene Promoter Region
  43. Rational engineering of a human GFP-like protein scaffold for humanized targeted nanomedicines
  44. Biodistribution of 68/67Ga-Radiolabeled Sphingolipid Nanoemulsions by PET and SPECT Imaging
  45. Exploring the Interaction of Curaxin CBL0137 with G-Quadruplex DNA Oligomers
  46. The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis
  47. Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake
  48. Structural Effects of Incorporation of 2'‐Deoxy‐2'2'‐Difluorodeoxycytidine (Gemcitabine) in A‐ and B‐Form Duplexes
  49. Parallel G-quadruplex Structures Increase Cellular Uptake and Cytotoxicity of 5-Fluoro-2′-deoxyuridine Oligomers in 5-Fluorouracil Resistant Cells
  50. Biomedical Applications of DNA-nanostructures
  51. EcoRII Restriction Endonuclease Forms Specific Contacts to the Bases of Its Target Sequence Flipped from DNA in a Transition Complex with Photoactivatable Substrates
  52. G-quadruplex binding properties of a potent PARP-1 inhibitor derived from 7-azaindole-1-carboxamide
  53. Oligonucleotides Containing 1-Aminomethyl or 1-Mercaptomethyl-2-deoxy-d-ribofuranoses: Synthesis, Purification, Characterization, and Conjugation with Fluorophores and Lipids
  54. Nanoparticles for Brain Drug Delivery
  55. Nucleic Acids Chemistry
  56. Preparation of Lipid-Conjugated siRNA Oligonucleotides for Enhanced Gene Inhibition in Mammalian Cells
  57. Studies on the interactions of Ag(i) with DNA and their implication on the DNA-templated synthesis of silver nanoclusters and on the interaction with complementary DNA and RNA sequences
  58. Design and engineering of tumor-targeted, dual-acting cytotoxic nanoparticles
  59. Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery
  60. Developing Protein–Antitumoral Drug Nanoconjugates as Bifunctional Antimicrobial Agents
  61. Triplex Hybridization-Based Nanosystem for the Rapid Screening of Pneumocystis Pneumonia in Clinical Samples
  62. Study of alkaloid berberine and its interaction with the human telomeric i-motif DNA structure
  63. Sorting hidden patterns in nanoparticle performance for glioblastoma using machine learning algorithms
  64. Non-viral mediated gene therapy in human cystic fibrosis airway epithelial cells recovers chloride channel functionality
  65. Influence of pH and a porphyrin ligand on the stability of a G-quadruplex structure within a duplex segment near the promoter region of the SMARCA4 gene
  66. Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins
  67. Fast and Accurate Pneumocystis Pneumonia Diagnosis in Human Samples Using a Label-Free Plasmonic Biosensor
  68. Brain Angiogenesis Induced by Nonviral Gene Therapy with Potential Therapeutic Benefits for Central Nervous System Diseases
  69. Niosome-Based Approach for In Situ Gene Delivery to Retina and Brain Cortex as Immune-Privileged Tissues
  70. Ethylcellulose nanoparticles as a new “in vitro” transfection tool for antisense oligonucleotide delivery
  71. Sulfonamide as amide isostere for fine-tuning the gelation properties of physical gels
  72. Liposomes‐ in ‐Chitosan Hydrogels: Challenges and Opportunities for Biomedical Applications
  73. Alginate Hydrogels as Scaffolds and Delivery Systems to Repair the Damaged Spinal Cord
  74. A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor
  75. Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41
  76. Aptamer-peptide conjugates as a new strategy to modulate human α-thrombin binding affinity
  77. Cationic niosome-based hBMP7 gene transfection of neuronal precursor NT2 cells to reduce the migration of glioma cells in vitro
  78. Study of conformational transitions of i-motif DNA using time-resolved fluorescence and multivariate analysis methods
  79. Gene delivery to the rat retina by non-viral vectors based on chloroquine-containing cationic niosomes
  80. The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry
  81. Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
  82. On the Race for More Stretchable and Tough Hydrogels
  83. Parallel Clamps and Polypurine Hairpins (PPRH) for Gene Silencing and Triplex‐Affinity Capture: Design, Synthesis, and Use
  84. Efficient bioactive oligonucleotide‐protein conjugation for cell‐targeted cancer therapy
  85. Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery
  86. Expanding the limits of amide–triazole isosteric substitution in bisamide-based physical gels
  87. Overview of DNA Self-Assembling: Progresses in Biomedical Applications
  88. Detection of a microRNA involved in human disease
  89. Detection of DNA methylation
  90. Gene transfer to rat cerebral cortex mediated by polysorbate 80 and poloxamer 188 nonionic surfactant vesicles
  91. Synthesis of Oligonucleotides Carrying Nucleic Acid Derivatives of Biomedical and Structural Interest
  92. Successful evaluation of a nanodrug against metastasis
  93. Preparation of new compounds with interesting porperties in biomedicine
  94. siRNA Modified with 2′-Deoxy-2′-C -methylpyrimidine Nucleosides
  95. Evaluation of the effect of polymorphism on G-quadruplex-ligand interaction by means of spectroscopic and chromatographic techniques
  96. Synthesis, Characterization, and Self-Assembly of a Tetrathiafulvalene (TTF)–Triglycyl Derivative
  97. Isosteric Substitution of 4H-1,2,4-Triazole by 1H-1,2,3-Triazole in Isophthalic Derivative Enabled Hydrogel Formation for Controlled Drug Delivery
  98. Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates
  99. Stem cell-based gene delivery mediated by cationic niosomes for bone regeneration
  100. Exploring PAZ/3′-overhang interaction to improve siRNA specificity. A combined experimental and modeling study
  101. DNA-based nanoscaffolds as vehicles for 5-fluoro-2′-deoxyuridine oligomers in colorectal cancer therapy
  102. Electrochemical and AFM Characterization of G-Quadruplex Electrochemical Biosensors and Applications
  103. Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies
  104. Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes
  105. Study of light-induced formation of photodimers in the i-motif nucleic acid structure by rapid-scan FTIR difference spectroscopy and hybrid hard- and soft-modelling
  106. AS1411-decorated niosomes as effective nanocarriers for Ru(iii)-based drugs in anticancer strategies
  107. Lipid-Oligonucleotide Conjugates Forming G-Quadruplexes (Lipoquads) as Potent Inhibitors of HIV Entry
  108. i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene
  109. DNA-Origami-Aided Lithography for Sub-10 Nanometer Pattern Printing
  110. Biochemistry of RNA Silencing
  111. Cover Picture: Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues (ChemBioChem 12/2017)
  112. Transfection of Antisense Oligonucleotides Mediated by Cationic Vesicles Based on Non-Ionic Surfactant and Polycations Bearing Quaternary Ammonium Moieties
  113. Stabilization of Telomeric I-Motif Structures by (2′S )-2′-Deoxy-2′-C -Methylcytidine Residues
  114. The effect of l -thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures
  115. Erratum: Corrigendum: The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein
  116. Antiviral activity of lipid-DNA molecules
  117. DNA-Origami-Driven Lithography for Patterning on Gold Surfaces with Sub-10 nm Resolution
  118. Boronic acid-modified alginate enables direct formation of injectable, self-healing and multistimuli-responsive hydrogels
  119. Cationic nioplexes-in-polysaccharide-based hydrogels as versatile biodegradable hybrid materials to deliver nucleic acids
  120. Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms
  121. The impact of an extended nucleobase-2′-deoxyribose linker in the biophysical and biological properties of oligonucleotides
  122. Meet Our Editorial Board Member
  123. Controlling the Reversible Assembly of Liposomes through a Multistimuli Responsive Anchored DNA
  124. Glucose-Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA
  125. The role of helper lipids in the intracellular disposition and transfection efficiency of niosome formulations for gene delivery to retinal pigment epithelial cells
  126. The Effect of Small Cosolutes that Mimic Molecular Crowding Conditions on the Stability of Triplexes Involving Duplex DNA
  127. siRNA and RNAi optimization
  128. The influence of the polar head-group of synthetic cationic lipids on the transfection efficiency mediated by niosomes in rat retina and brain
  129. Biodegradable liposome-encapsulated hydrogels for biomedical applications: a marriage of convenience
  130. Cellular uptake studies of antisense oligonucleotides using G-quadruplex-nanostructures. The effect of cationic residue on the biophysical and biological properties
  131. Nioplexes encapsulated in supramolecular hybrid biohydrogels as versatile delivery platforms for nucleic acids
  132. Understanding the effect of the nature of the nucleobase in the loops on the stability of the i-motif structure
  133. Label-free electrochemical DNA sensor using “click”-functionalized PEDOT electrodes
  134. Sensitive and label-free detection of miRNA-145 by triplex formation
  135. Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers
  136. 1-[2,3-Bis(tetradecyloxy)propyl]-3-[2-(piperazin-1-yl)ethyl]urea
  137. New Insights into Gene Delivery to Human Neuronal Precursor NT2 Cells: A Comparative Study between Lipoplexes, Nioplexes, and Polyplexes
  138. Synthesis of oligonucleotides carrying fluorescently labelled O6-alkylguanine for measuring hAGT activity
  139. RNA modified with acyclic threoninol nucleic acids for RNA interference
  140. Protamine/DNA/Niosome Ternary Nonviral Vectors for Gene Delivery to the Retina: The Role of Protamine
  141. Atomic Force Microscopy and Voltammetric Investigation of Quadruplex Formation between a Triazole-Acridine Conjugate and Guanine-Containing Repeat DNA Sequences
  142. Modulation of the RNA Interference Activity Using Central Mismatched siRNAs and Acyclic Threoninol Nucleic Acids (aTNA) Units
  143. Glucose Conjugation of Anti-HIV-1 Oligonucleotides Containing Unmethylated CpG Motifs Reduces Their Immunostimulatory Activity
  144. Niosomes based on synthetic cationic lipids for gene delivery: the influence of polar head-groups on the transfection efficiency in HEK-293, ARPE-19 and MSC-D1 cells
  145. Novel non-viral gene delivery systems composed of carbosilane dendron functionalized nanoparticles prepared from nano-emulsions as non-viral carriers for antisense oligonucleotides
  146. The effect of a cytidine derivative on the stability of intramolecular i-motifs was investigated.
  147. RNA/aTNA Chimeras: RNAi Effects and Nucleases Resistance of Single and Double Stranded RNAs
  148. Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles
  149. Cationic vesicles based on non-ionic surfactant and synthetic aminolipids mediate delivery of antisense oligonucleotides into mammalian cells
  150. DNA Nanoarchitectures: Steps towards Biological Applications
  151. Quadruplex Nanostructures of d(TGGGGT): Influence of Sodium and Potassium Ions
  152. Oligonucleotide delivery: a patent review (2010 – 2013)
  153. Effects of Sugar Functional Groups, Hydrophobicity, and Fluorination on Carbohydrate–DNA Stacking Interactions in Water
  154. Direct Covalent Attachment of DNA Microarrays by Rapid Thiol–Ene “Click” Chemistry
  155. A Novel Formulation Based on 2,3-Di(tetradecyloxy)propan-1-amine Cationic Lipid Combined with Polysorbate 80 for Efficient Gene Delivery to the Retina
  156. to fold or to dimerize a dilema for modified TBA
  157. Fundamental aspects of the nucleic acid i-motif structures
  158. A novel cationic niosome formulation for gene delivery to the retina
  159. Challenges and Opportunities for Oligonucleotide-Based Therapeutics by Antisense and RNA Interference Mechanisms
  160. Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops
  161. Double-tailed lipid modification as a promising candidate for oligonucleotide delivery in mammalian cells
  162. Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates
  163. DNA Origami as a DNA Repair Nanosensor at the Single-Molecule Level
  164. Electrostatic Binding and Hydrophobic Collapse of Peptide–Nucleic Acid Aggregates Quantified Using Force Spectroscopy
  165. Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
  166. Efficient Self-Assembly in Water of Long Noncovalent Polymers by Nucleobase Analogues
  167. Functionalization of the 3′-Ends of DNA and RNA Strands with N-ethyl-N-coupled Nucleosides: A Promising Approach To Avoid 3′-Exonuclease-Catalyzed Hydrolysis of Therapeutic Oligonucleotides
  168. Carbohydrate-DNA Interactions at G-Quadruplexes: Folding and Stability Changes by Attaching Sugars at the 5′-End
  169. The detection of a protein involved in coagulation using fluorescence
  170. Self-assembled G-quadruplex nanostructures: AFM and voltammetric characterization
  171. Biophysical and RNA Interference Inhibitory Properties of Oligonucleotides Carrying Tetrathiafulvalene Groups at Terminal Positions
  172. 20 Supramolecular polymerization of nucleobase-like monomers in water
  173. Porphyrin binding mechanism is altered by protonation at the loops in G-quadruplex DNA formed near the transcriptional activation site of the human c-kit gene
  174. Oligonucleotide-Peptide Conjugates: Solid-Phase Synthesis under Acidic Conditions and Use in ELISA Assays
  175. Synthesis of Steroid–Oligonucleotide Conjugates for a DNA Site-Encoded SPR Immunosensor
  176. Receptor-Based Virtual Screening and Biological Characterization of Human Apurinic/Apyrimidinic Endonuclease (Ape1) Inhibitors
  177. Synthesis of Oligonucleotides Carrying Thiol Groups Using a Simple Reagent Derived from Threoninol
  178. Development of an impedimetric DNA-biosensor based on layered double hydroxide for the detection of long ssDNA sequences
  179. The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer
  180. Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives
  181. Impact of Methylation on the Physical Properties of DNA
  182. Structure of Triplex DNA in the Gas Phase
  183. Synthesis and Structural Characterization of Stable Branched DNA G-Quadruplexes Using the Trebler Phosphoramidite
  184. Synthesis and in vitro inhibition properties of oligonucleotide conjugates carrying amphipathic proline-rich peptide derivatives of the sweet arrow peptide (SAP)
  185. Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications
  186. Synthesis and in vitro Inhibition Properties of siRNA Conjugates Carrying Acridine and Quindoline Moieties
  187. Functionally Enhanced siRNA Targeting TNFα Attenuates DSS-induced Colitis and TLR-mediated Immunostimulation in Mice
  188. Facile Modification of Silica Substrates Provides a Platform for Direct‐Writing Surface Click Chemistry
  189. Sensitive and label-free biosensing of RNA with predicted secondary structures by a triplex affinity capture method
  190. Apolar carbohydrates as DNA capping agents
  191. Interstrand interactions on DNA duplexes modified by TTF units at the 3′ or 5′-ends
  192. Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5′-(C3TA2)4-3′ sequence of the human telomere
  193. Use of Oligonucleotides Carrying Photolabile Groups for the Control of the Deposition of Nanoparticles in Surfaces and Nanoparticle Association
  194. Functionalization of Surfaces with Synthetic Oligonucleotides
  195. Functionalization and Self-Assembly of DNA Bidimensional Arrays
  196. Acridine and quindoline oligomers linked through a 4-aminoproline backbone prefer G-quadruplex structures
  197. A Direct, Efficient Method for the Preparation of siRNAs Containing Ribo-likeNorthBicyclo[3.1.0]hexane Pseudosugars
  198. Synthesis and Properties of Oligodeoxynucleotides Carrying 2-Aminopurine
  199. Evaluation of the structure–activity relationship of thrombin with thrombin binding aptamers by voltammetry and atomic force microscopy
  200. Effect of North Bicyclo[3.1.0]hexane 2′-Deoxy-pseudosugars on RNA Interference: A Novel Class of siRNA Modification
  201. Highly Polar Carbohydrates Stack onto DNA Duplexes via CH/π Interactions
  202. Synthesis of Lipid-Oligonucleotide Conjugates for RNA Interference Studies
  203. Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations
  204. Branched RNA: A New Architecture for RNA Interference
  205. Synthesis of Oligonucleotide–Peptide Conjugates for Biomedical and Technological Applications
  206. Synthesis and properties of small interfering RNA duplexes carrying 5-ethyluridine residues
  207. Synthesis and structural properties of oligonucleotides covalently linked to acridine and quindoline derivatives through a threoninol linker
  208. Chemical equilibria studies using multivariate analysis methods
  209. Synthesis of Oligonucleotides Carrying Amino Lipid Groups at the 3′-End for RNA Interference Studies
  210. Synthesis and Properties of Oligonucleotides Carrying Isoquinoline Imidazo[1,2-a]azine Fluorescent Units
  211. Solid-Phase Synthesis of Oligodeoxynucleotides Containing N4-[2-(t-butyldisulfanyl)ethyl]-5-methylcytosine Moieties
  212. Synthesis, Cell-Surface Binding, and Cellular Uptake of Fluorescently Labeled Glucose−DNA Conjugates with Different Carbohydrate Presentation
  213. Stepwise synthesis of oligonucleotide–peptide conjugates containing guanidinium and lipophilic groups in their 3′-termini
  214. Spectrometric study of the oligodeoxyribonucleotide protonation in aqueous solution
  215. Fabrication of patterned surfaces by photolithographic exposure of DNA hairpins carrying a novel photolabile group
  216. Triplex-Stabilizing Properties of Parallel Clamps Carrying LNA Derivatives at theHoogsteenStrand
  217. Modified siRNAs for the study of the PAZ domain
  218. Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection ofO6-Alkylguanine-DNA Alkyltransferase Activity
  219. G-Quadruplex Nucleic Acids
  220. Structural Properties of G,T-Parallel Duplexes
  221. Synthesis and G-Quadruplex-Binding Properties of Defined Acridine Oligomers
  222. Thrombin-Binding Aptamer Quadruplex Formation: AFM and Voltammetric Characterization
  223. pH-Modulated Watson–Crick Duplex–Quadruplex Equilibria of Guanine-Rich and Cytosine-Rich DNA Sequences 140 Base Pairs Upstream of thec-kitTranscription Initiation Site
  224. Modified Oligonucleotides for Biosensing Applications
  225. Unique Tautomeric and Recognition Properties of Thioketothymines?
  226. DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site
  227. α,γ-Peptide Nanotube Templating of One-Dimensional Parallel Fullerene Arrangements
  228. Assembly of Two-Dimensional DNA Crystals CarryingN4-[2-(tert-Butyldisulfanyl)ethyl]cytosine Residues
  229. Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamer
  230. Targeting the G-quadruplex-forming region near the P1 promoter in the human BCL-2 gene with the cationic porphyrin TMPyP4 and with the complementary C-rich strand
  231. Fluorescence site-encoded DNA addressable hapten microarray for anabolic androgenic steroids
  232. Classification of nucleic acids structures by means of the chemometric analysis of circular dichroism spectra
  233. Photocleavage of Peptides and Oligodeoxynucleotides Carrying 2-Nitrobenzyl Groups
  234. Stepwise synthesis of RNA conjugates carrying peptide sequences for RNA interference studies
  235. Synthesis and Hybridization Properties of Modified Oligodeoxynucleotides Carrying Non-Natural Bases
  236. Amino-acids condensations in the preparation of Nα-9-fluorenylrnethyloxycarbonylamino-acids with 9-fluorenylmethylchloroformate
  237. Experimental Measurement of Carbohydrate-Aromatic Stacking in Water by Using a Dangling-Ended DNA Model System
  238. Study of the interaction between the G-quadruplex-forming thrombin-binding aptamer and the porphyrin 5,10,15,20-tetrakis-(N-methyl-4-pyridyl)-21,23H-porphyrin tetratosylate
  239. Design, synthesis and antiproliferative properties of oligomers with chromophore units linked by amide backbones
  240. Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones
  241. Incorporation of Zebularine from its 2′-Deoxyribonucleoside Triphosphate Derivative and Activity as a Template-Coding Nucleobase
  242. 8-Amino guanine accelerates tetramolecular G-quadruplex formation
  243. Synthesis of Oligonucleotide Derivatives Using ChemMatrix Supports
  244. Solution equilibria of the i-motif-forming region upstream of the B-cell lymphoma-2 P1 promoter
  245. Synthesis of Oligonucleotides Carrying 5′-5′ Linkages Using Copper-Catalyzed Cycloaddition Reactions
  246. A Flexible Method for the Fabrication of Gold Nanostructures Using Oligonucleotide Derivatives
  247. New developments in the synthesis of oligonucleotide-peptide conjugates
  248. Triplex Formation Using Oligonucleotide Clamps Carrying 8-Aminopurines
  249. ds-Oligonucleotide–Peptide Conjugates Featuring Peptides from the Leucine-Zipper Region of Fos as Switchable Receptors for the Oncoprotein Jun
  250. Analysis of Interaction between Dendriplexes and Bovine Serum Albumin
  251. Water-Soluble Carbosilane Dendrimers: Synthesis Biocompatibility and Complexation with Oligonucleotides; Evaluation for Medical Applications
  252. Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins
  253. First Characterization of a Biosensor for Large DNA Molecules using Quartz Crystal Microbalance and Impedance Spectroscopy
  254. Solid-Phase Synthesis of Modified Oligonucleotides
  255. Spectroscopic study of the interaction of actinomycin D with oligonucleotides carrying the central base sequences -XGCY- and -XGGCCY- using multivariate methods
  256. Erratum
  257. Trimethylguanosine Nucleoside Inhibits Cross-Linking Between Snurportin 1 and m3G-CAPPED U1 snRNA
  258. Efficient Sequence-Specific Purification of Listeria innocua mRNA Species by Triplex Affinity Capture with Parallel Tail-Clamps
  259. Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand
  260. DNA-templated assembly of nanoscale architectures for next-generation electronic devices
  261. Strand Displacement of Double-Stranded DNA by Triplex-Forming Antiparallel Purine-Hairpins
  262. Destabilization of Quadruplex DNA by 8-Aminoguanine
  263. Magnetically Trigged Direct Electrochemical Detection of DNA Hybridization Using Au67Quantum Dot as Electrical Tracer
  264. Toward an ICPMS-Linked DNA Assay Based on Gold Nanoparticles Immunoconnected through Peptide Sequences
  265. A Straightforward Synthesis of 5‘-Peptide Oligonucleotide Conjugates UsingNα-Fmoc-Protected Amino Acids
  266. DNA-templated assembly of nanoscale architectures
  267. “Parallel” and “Antiparallel Tail-Clamps” Increase the Efficiency of Triplex Formation with Structured DNA and RNA Targets
  268. Synthesis and Triplex-Forming Properties of Cyclic Oligonucleotides with (G,A)-Antiparallel Strands
  269. Hybridization and Melting Behavior of Peptide Nucleic Acid (PNA) Oligonucleotide Chimeras Conjugated to Gold Nanoparticles
  270. DNA-Templated Assembly of a Protein-Functionalized Nanogap Electrode
  271. Synthesis of OligonucleotidePeptide Conjugates Carrying the c-myc Peptide Epitope as Recognition System
  272. Synthesis and Triple-Helix-Stabilization Properties of Branched Oligonucleotides Carrying 8-Aminoadenine Moieties
  273. Synthesis and Properties of Oligonucleotides Carrying Cryptolepine Derivatives
  274. Synthesis of Oligoribonucleotides Containing 4‐Thiouridine Using the Convertible Nucleoside Approach and the 1‐(2‐Fluorophenyl)‐4‐Methoxypiperidin‐4‐yl Group
  275. Transgenic Rice Plants Expressing the Antifungal AFP Protein from Aspergillus Giganteus Show Enhanced Resistance to the Rice Blast Fungus Magnaporthe Grisea
  276. Antiparallel Triple Helices. Structural Characteristics and Stabilization by 8-Amino Derivatives
  277. Potent Inhibition ofHhaI DNA Methylase by the Aglycon of 2-(1H)-Pyrimidinone Riboside (Zebularine) at the GCGC Recognition Domain
  278. Properties of Triple Helices Formed by Oligonucleotides Containing 8-Aminopurines
  279. Synthesis of Branched Oligonucleotides as Templates for the Assembly of Nanomaterials
  280. Convenient Synthesis of 8-Amino-2′-deoxyadenosine
  281. Peptide–PNA Conjugates: Targeted Transport of Antisense Therapeutics into Tumors
  282. Imaging the DNA and nanoparticle components of a self-assembled nanoscale architecture
  283. Synthesis of labelled PNA oligomers by a post-synthetic modification approach
  284. Synthesis, stability, and protonation studies of a self-complementary dodecamer containing the modified nucleoside 2?-deoxyzebularine
  285. DNA-Controlled Assembly of Protein-Modified Gold Nanocrystals
  286. Synthesis and properties of radiolabeled CPTA-oligonucleotides
  287. Nanotechnology: Carbon nanotubes with DNA recognition
  288. DNA triple helices and biomedicine
  289. Biofunctionalization of Silica-Coated CdTe and Gold Nanocrystals
  290. Inhibition of HhaI DNA (Cytosine-C5) Methyltransferase by Oligodeoxyribonucleotides Containing 5-Aza-2′-deoxycytidine: Examination of the Intertwined Roles of Co-factor, Target, Transition State Structure and Enzyme Conformation
  291. Additional Binding Sites for Anionic Phospholipids and Calcium Ions in the Crystal Structures of Complexes of the C2 Domain of Protein Kinase Cα
  292. Iodouracil-mediated photocrosslinking of DNA to EcoRII restriction endonuclease in catalytic conditions
  293. Hoogsteen-Based Parallel-Stranded Duplexes of DNA. Effect of 8-Amino-purine Derivatives
  294. Plasmid transcriptional repressor CopG oligomerises to render helical superstructures unbound and in complexes with oligonucleotides
  295. Parallel-stranded hairpins containing 8-aminopurines. novel efficient probes for triple-helix formation
  296. SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES CONTAINING 8-BROMO-2′-DEOXYGUANOSINE
  297. AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES
  298. Preparation and Evaluation of Tumor-Targeting Peptide−Oligonucleotide Conjugates
  299. Synthesis and Hybridization Properties of DNA–PNA Chimeras Carrying 5-Bromouracil and 5-Methylcytosine
  300. Intracellular distribution of digoxigenin-labeled phosphorothioate oligonucleotides
  301. Synthesis and Binding Properties of Oligonucleotides Carrying Nuclear Localization Sequences
  302. “Action-at-a-Distance” Mutagenesis
  303. Theoretical calculations, synthesis and base pairing properties of oligonucleotides containing 8-amino-2'-deoxyadenosine
  304. The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator
  305. Synthesis of Oligodeoxynucleotides ContainingN4-Mercaptoethylcytosine and Their Use in the Preparation of Oligonucleotide−Peptide Conjugates Carrying c-mycTag-Sequence
  306. Triple helix stabilization properties of oligonucleotides containing 8-amino-2′-deoxyguanosine
  307. Biochemical basis of SOS-induced mutagenesis in Escherichia coli : Reconstitution of in vitro lesion bypass dependent on the UmuD′ 2 C mutagenic complex an...
  308. Exonuclease−Polymerase Active Site Partitioning of Primer−Template DNA Strands and Equilibrium Mg2+Binding Properties of Bacteriophage T4 DNA Polymerase†
  309. A Second-Step Splicing Activity Is Conserved from Yeast to Human
  310. 2′-O-Propargyl oligoribonucleotides: Synthesis and hybridisation
  311. Tandem 5′-GA:GA-3′ mismatches account for the high stability of the fold-back structures formed by the centromeric Drosophila dodeca-satellite 1 1Edited by I. Tinoco
  312. Preparation and Properties of Oligodeoxynucleotides Containing 5-Iodouracil and 5-Bromo- and 5-Iodocytosine
  313. Solid-phase synthesis of branched RNA and branched DNA/RNA chimeras
  314. Initiation of replication of plasmid pMV158: mechanisms of DNA strand-transfer reactions mediated by the initiator RepB protein
  315. A simple method for the synthesis of 2′-O-alkylguanosine derivatives
  316. Abasic Translesion Synthesis by DNA Polymerase β Violates the “A-rule”
  317. New carbamate supports for the preparation of 3′-amino-modified oligonucleotides
  318. Synthesis of 1,2-diacyl-sn-glycerophosphadidylserine from egg phosphatidylcholine by phosphoramidite Methodology
  319. NMR Study of the Conformation of the 2-Aminopurine:Cytosine Mismatch in DNA†
  320. Spectroscopic and Calorimetric Characterizations of DNA Duplexes Containing 2-Aminopurine†
  321. Divalent Zinc Cations Induce the Formation of Two Distinct Homoduplexes of a d(GA)20 DNA Sequence
  322. Preparation and properties of oligodeoxynucleotides containing 4-O-butylthymine, 2-fluorohypoxanthine and 5-azacytosine1
  323. Preparation of oligonucleotide-dexamethasone conjugates
  324. Preparation of Oligonucleotides Containing Non-natural Base Analogues
  325. Dam methylase fromEscherichia coli: kinetic studies using modified DNA oligomers: hemimethylated substrates
  326. Digoxigenin-Labeled Phosphorothioate Oligonucleotides: A New Tool for the Study of Cellular Uptake
  327. Synthesis and properties of oligonucleotides containing the mutagenic base O4-benzylthymidine
  328. Use of NPE-Protecting Groups for the Preparation of Oligonucleotides Without Using Nucleophiles During the Final Deprotection
  329. Use of oligonucleotide-alkaline phosphatase conjugates as non-radioactive probes for rapid analysis of a proteinase inhibitor gene fromZea mays
  330. Nucleotide Insertion and Primer Extension at Abasic Template Sites in Different Sequence Contexts
  331. Pre-Steady-State Kinetic Analysis of Sequence-Dependent Nucleotide Excision by the 3'-Exonuclease Activity of Bacteriophage T4 DNA Polymerase
  332. Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258
  333. Chemical synthesis of a fully active transcriptional repressor protein.
  334. Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids
  335. Synthesis of Oligodeoxyribonucleotides Containing 2,6-Diaminopurine
  336. Criteria for the economic large scale solid-phase synthesis of oligonucleotides
  337. Solid-phase N-glycopeptide synthesis using allyl side-chain protected Fmoc-amino acids
  338. A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides
  339. Gel-phase 31P-NMR. A new analytical tool to evaluate solid phase oligonucleoside synthesis.
  340. Both O4-methylthymine and O4-ethylthymine preferentially form alkyl T.G pairs that do not block in vitro replication in a defined sequence
  341. Detection of hepatitis B virus DNA in human serumsamples: Use of digoxigenin-labeled oligonucleotides as modified primers for the polymerase chain reaction
  342. -2-(2,4-dinitrophenyl)ethyloxycarbonyl-amino acids, new base labile protected derivatives suitable for solid-phase peptide synthesis.
  343. S-2-(2,4-dinitrophenyl)ethyl--cysteine: a new derivative for solid-phase peptide synthesis
  344. A synthetic procedure for the preparation of oligonucleotides without using ammonia and its application for the synthesis of oligonucleotides containing 0-4-alkyl thymidines.
  345. Preparation of oligonucleotides containing dAICA using an unexpected side-reaction observed on a protected derivative of 2-aza-2′-deoxyinosine.
  346. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides II. Synthesis of protected peptides
  347. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides I : Synthesis of the supports and their application to oligonucleotide synthesis.
  348. Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal sequence.
  349. Syhthesis of Oligonucleotides Containing 4-0-Ethylthymidine
  350. O-aryl phosphoramidites: synthesis, reactivity and evaluation of their use for solid-phase synthesis of oligonucleotides
  351. Synthesis and characterization of oligodeoxynucleotides containing the mutagenic base analogue 4-O-ethylthymine
  352. Characterization of the high pH wobble structure of the 2-aminopurine·cytosine mismatch by N-15 NMR spectroscopy
  353. Ionized and wobble base-pairing for bromouracil-guanine in equilibrium under physiological conditions
  354. Structural and Dynamic Properties of a Bromouracil-Adenine Base Pair in DNA Studied by Proton NMR
  355. NMR studies of the stable mismatch purine-thymine in the self-complementary d(CGPuAATTTCG) duplex in solution
  356. NMR studies on an oligodeoxynucleotide containing 2-aminopurine opposite adenine
  357. Synthesis of Oligonucleotides Containing the Abasic Site Model Compound 1,4-Anhydro-2-Deoxy-D-Ribitol
  358. An abasic site in DNA. Solution conformation determined by proton NMR and molecular mechanics calculations
  359. On the use of s-t-butylsulphenyl group for protection of cysteine in solid-phase peptide synthesis using fmoc-amino acids
  360. Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR.
  361. Convergent solid phase peptide synthesis-III
  362. Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine
  363. Synthesis and properties of oligonucleotides containing 2′-deoxynebularine and 2′-deoxyxanthosine
  364. Diketopiperazine formation in acetamido-and nitrobenzamido-bridgedpolymeric supports.