All Stories

  1. P4‐213: REDUCTION OF β‐AMYLOID AND PHOSPHO‐TAU IN TRANSGENIC MICE BY A NOVEL FUSION PROTEIN BIVALENT FOR A GENERAL AMYLOID INTERACTION MOTIF (GAIM)

    Article • Alzheimer s & Dementia, July 2014, Wiley

    Dr Rajaraman Krishnan

  2. P2‐067: IMMUNOGLOBULIN‐GENERAL AMYLOID INTERACTION MOTIF (IG‐GAIM) MOLECULES TARGET BETA AMYLOID AND NEUROFIBRILLARY TANGLES IN VITRO AND IN VIVO

    Article • Alzheimer s & Dementia, July 2014, Wiley

    Dr Rajaraman Krishnan

  3. A Bacteriophage Capsid Protein Provides a General Amyloid Interaction Motif (GAIM) That Binds and Remodels Misfolded Protein Assemblies

    Article • Journal of Molecular Biology, June 2014, Elsevier

    Dr Rajaraman Krishnan, Professor D.A. Kirschner

  4. P2–050: A novel mechanism that targets misfolded protein assemblies

    Article • Alzheimer s & Dementia, July 2013, Wiley

    Dr Rajaraman Krishnan

  5. P4–290: Novel fusion protein bivalent for a general amyloid interaction motif reduces beta‐amyloid aggregates in transgenic mice

    Article • Alzheimer s & Dementia, July 2013, Wiley

    Dr Rajaraman Krishnan

  6. Conserved features of intermediates in amyloid assembly determine their benign or toxic states

    Article • Proceedings of the National Academy of Sciences, June 2012, Proceedings of the National Academy of Sciences

    Dr Rajaraman Krishnan

  7. P4‐412: NPT001: A candidate therapeutic for clearance of beta‐amyloid and tau aggregates in Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2011, Wiley

    Dr Rajaraman Krishnan, Professor D.A. Kirschner

  8. P2‐456: NPT001: A candidate therapeutic for clearance of β‐amyloid and tau aggregates in Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2011, Wiley

    Dr Rajaraman Krishnan, Professor D.A. Kirschner

  9. Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered Proteins

    Article • Molecular Cell, July 2011, Elsevier

    Dr Rajaraman Krishnan

  10. The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

    Article • The EMBO Journal, March 2011, Springer Science + Business Media

    Dr Rajaraman Krishnan

  11. A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures

    Article • Proceedings of the National Academy of Sciences, February 2007, Proceedings of the National Academy of Sciences

    Dr Rajaraman Krishnan

  12. Structural insights into a yeast prion illuminate nucleation and strain diversity

    Article • June 2005

    Dr Rajaraman Krishnan

  13. Effects of Q/N-rich, polyQ, and non-polyQ amyloids on thede novoformation of the [PSI+] prion in yeast and aggregation of Sup35in vitro

    Article • Proceedings of the National Academy of Sciences, August 2004, Proceedings of the National Academy of Sciences

    Dr Rajaraman Krishnan

  14. Interaction of human recombinant αA‐ and αB‐crystallins with early and late unfolding intermediates of citrate synthase on its thermal denaturation

    Article • FEBS Letters, May 2001, Wiley

    Dr Rajaraman Krishnan

  15. Structural perturbation of α-crystallin and its chaperone-like activity

    Article • International Journal of Biological Macromolecules, May 1998, Elsevier

    Dr Rajaraman Krishnan

  16. Molten-Globule State of Carbonic Anhydrase Binds to the Chaperone-like  -Crystallin

    Article • Journal of Biological Chemistry, November 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Rajaraman Krishnan