All Stories

  1. Discovery of new piperaquine hybrid analogs linked by triazolopyrimidine and pyrazolopyrimidine scaffolds with antiplasmodial and transmission blocking activities

    Article • European Journal of Medicinal Chemistry, March 2024, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  2. Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi

    Article • Scientific Reports, October 2023, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  3. Using molecular networking and docking to explore arginase inhibitors among Drimys brasiliensis chemical constituents

    Article • Medicinal Chemistry Research, July 2023, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  4. Editorial: Antimalarial chemotherapy in the XXIst century, volume II

    Article • Frontiers in Pharmacology, June 2023, Frontiers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  5. Polyketide- and Terpenoid-Derived Metabolites Produced by a Marine-Derived Fungus, Peroneutypa sp.

    Article • Journal of Natural Products, June 2023, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  6. Copper-Catalyzed Synthesis of Pyrrolo[1,2-c]quinazolines and Pyrrolo[2,1-a]isoquinolines and Antiplasmodial Evaluation

    Article • The Journal of Organic Chemistry, June 2023, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  7. Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease

    Article • Journal of Biological Chemistry, March 2023, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  8. Inhibition of 3-Hydroxykynurenine Transaminase from Aedes aegypti and Anopheles gambiae: A Mosquito-Specific Target to Combat the Transmission of Arboviruses

    Article • ACS Bio & Med Chem Au, February 2023, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  9. Effects of Dimerization, Dendrimerization, and Chirality in p-BthTX-I Peptide Analogs on the Antibacterial Activity and Enzymatic Inhibition of the SARS-CoV-2 PLpro Protein

    Article • Pharmaceutics, January 2023, MDPI AG

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  10. Discovery of aminothiazole derivatives as a chemical scaffold for glutaminase inhibition

    Article • Results in Chemistry, January 2023, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  11. Editorial: Antimalarial chemotherapy in the XXIst century

    Article • Frontiers in Pharmacology, December 2022, Frontiers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  12. Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues

    Article • International Journal for Parasitology Drugs and Drug Resistance, December 2022, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  13. New Strategies for Novel Drugs: Antimicrobial Peptides Containing Ferrocene with Improved Antifungal and Antiplasmodial Biological Activity

    Article • Protein and Peptide Letters, December 2022, Bentham Science Publishers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  14. Natural Compounds as Non-Nucleoside Inhibitors of Zika Virus Polymerase through Integration of In Silico and In Vitro Approaches

    Article • Pharmaceuticals, November 2022, MDPI AG

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  15. Discovery of New Zika Protease and Polymerase Inhibitors through the Open Science Collaboration Project OpenZika

    Article • Journal of Chemical Information and Modeling, October 2022, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  16. Structural basis of nirmatrelvir and ensitrelvir resistance profiles against SARS-CoV-2 Main Protease naturally occurring polymorphisms

    Article • September 2022, Cold Spring Harbor Laboratory Press

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  17. Antimicrobial activity of some celastroloids and their derivatives

    Article • Medicinal Chemistry Research, July 2022, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  18. Synthesis, Structure–Activity Relationships, and Parasitological Profiling of Brussonol Derivatives as New Plasmodium falciparum Inhibitors

    Article • Pharmaceuticals, June 2022, MDPI AG

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  19. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

    Article • Nature Communications, April 2022, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  20. Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins

    Article • Bioorganic Chemistry, March 2022, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  21. Discovery of (E)-4-styrylphenoxy-propanamide: A dual PPARα/γ partial agonist that regulates high-density lipoprotein-cholesterol levels, modulates adipogenesis, and improves glucose tolerance in diet-induced obese mice

    Article • Bioorganic Chemistry, March 2022, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  22. Synthesis and antiplasmodial assessment of nitazoxanide and analogs as new antimalarial candidates

    Article • Medicinal Chemistry Research, January 2022, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  23. New Isoquinoline Alkaloids from Paraphaeosphaeria sporulosa F03, a Fungal Endophyte Isolated from Paepalanthus planifolius

    Article • Planta Medica, January 2022, Thieme Publishing Group

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  24. High-Throughput Screening Reveals New Glutaminase Inhibitor Molecules

    Article • ACS Pharmacology & Translational Science, December 2021, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  25. Parasitological profiling shows 4(1H)-quinolone derivatives as new lead candidates for malaria

    Article • European Journal of Medicinal Chemistry Reports, December 2021, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  26. The Methionine 549 and Leucine 552 Residues of Friedelin Synthase from Maytenus ilicifolia Are Important for Substrate Binding Specificity

    Article • Molecules, November 2021, MDPI AG

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  27. ‘Molecular constipation’ caused by a new antimalarial drug candidate.

    Article • Proceedings of the National Academy of Sciences, September 2021, Proceedings of the National Academy of Sciences

    Leann Tilley, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  28. Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors

    Article • Molecules, August 2021, MDPI AG

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  29. Anthelmintic activity of a nanoformulation based on thiophenes identified in Tagetes patula L. (Asteraceae) against the small ruminant nematode Haemonchus contortus

    Article • Acta Tropica, July 2021, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  30. Antiprotozoal and Antibacterial Activity of Ravenelin, a Xanthone Isolated from the Endophytic Fungus Exserohilum rostratum

    Article • Molecules, June 2021, MDPI AG

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  31. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  32. Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors

    Article • ACS Infectious Diseases, April 2021, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  33. Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

    Article • Journal of Medicinal Chemistry, April 2021, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  34. Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors

    Article • Bioorganic Chemistry, April 2021, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  35. 3-aryl-indolinones derivatives as antiplasmodial agents: synthesis, biological activity and computational analysis

    Article • Natural Product Research, March 2021, Taylor & Francis

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  36. Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors

    Article • European Journal of Medicinal Chemistry, January 2021, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  37. A novel scaffold to fight Pseudomonas aeruginosa pyocyanin production: early steps to novel antivirulence drugs

    Article • Future Medicinal Chemistry, August 2020, Future Science

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  38. Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 in vitro infection using a phenotypic screening strategy and network-analysis to predict their potential to treat covid-19

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  39. QSAR studies on benzothiophene derivatives as Plasmodium falciparum N‐myristoyltransferase inhibitors: Molecular insights into affinity and selectivity

    Article • Drug Development Research, February 2020, Wiley

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  40. Chemical Prospection of Qualea grandiflora Mart. Fruit and Stem Extracts and Their in vitro and in vivo Antiplasmodial Activity

    Article • Journal of the Brazilian Chemical Society, January 2020, Sociedade Brasileira de Quimica (SBQ)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  41. Discovery of 1,2,4-oxadiazole derivatives as a novel class of noncompetitive inhibitors of 3-hydroxykynurenine transaminase (HKT) from Aedes aegypti

    Article • Bioorganic & Medicinal Chemistry, January 2020, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  42. Antiplasmodial profile of selected compounds from Malaria Box: in vitro evaluation, speed of action and drug combination studies

    Article • Malaria Journal, December 2019, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  43. Structural and mechanistic insight from antiviral and antiparasitic enzyme drug targets for tropical infectious diseases

    Article • Current Opinion in Structural Biology, December 2019, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  44. New Molecular Targets and Strategies for Antimalarial Discovery

    Article • Current Medicinal Chemistry, October 2019, Bentham Science Publishers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  45. Organocatalytic asymmetric vinylogous 1,4-addition of α,α-Dicyanoolefins to chalcones under a bio-based reaction media: Discovery of new Michael adducts with antiplasmodial activity

    Article • Tetrahedron, June 2019, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  46. In vitro bioassay guided anti-dermatophyte and cytotoxic activities from Piper umbellatum L. Miq. led to 4-nerolidylcatechol

    Article • Natural Product Research, February 2019, Taylor & Francis

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO, Rosemeire Pietro

  47. In vitro Antiplasmodial Activities of Alkaloids Isolated from Roots of Worsleya procera (Lem.) Traub (Amaryllidaceae)

    Article • Journal of the Brazilian Chemical Society, January 2019, Sociedade Brasileira de Quimica (SBQ)

    Prof. Javier Alcides Ellena, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  48. Synthesis, Profiling, and in Vivo Evaluation of Cyclopeptides Containing N-Methyl Amino Acids as Antiplasmodial Agents

    Article • ACS Medicinal Chemistry Letters, December 2018, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  49. Dimeric chalcones from Myracrodruon urundeuva act as cathepsin V inhibitors

    Article • Phytochemistry, October 2018, Elsevier

    Dr Elenilson Godoy Alves Filho, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  50. Phthalimide Derivatives with Bioactivity against Plasmodium falciparum: Synthesis, Evaluation, and Computational Studies Involving bc1 Cytochrome Inhibition

    Article • ACS Omega, August 2018, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  51. Molecular Cloning and Biochemical Characterization of Iron Superoxide Dismutase from Leishmania braziliensis

    Article • Molecular Biotechnology, June 2018, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  52. Discovery of Marinoquinolines as Potent and Fast-Acting Plasmodium falciparum Inhibitors with in Vivo Activity

    Article • Journal of Medicinal Chemistry, June 2018, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  53. Ceratocystis cacaofunesta genome analysis reveals a large expansion of extracellular phosphatidylinositol-specific phospholipase-C genes (PI-PLC)

    Article • BMC Genomics, January 2018, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  54. Isolation, Derivative Synthesis, and Structure–Activity Relationships of Antiparasitic Bromopyrrole Alkaloids from the Marine Sponge Tedania brasiliensis

    Article • Journal of Natural Products, January 2018, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  55. PERSPECTIVAS DA QUÍMICA MEDICINAL PARA O SÉCULO XXI: DESAFIOS E OPORTUNIDADES

    Article • Química Nova, January 2018, Sociedade Brasileira de Quimica (SBQ)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  56. A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K

    Article • PLoS ONE, October 2017, PLOS

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  57. A evolução da Química Medicinal no Brasil: avanços nos 40 anos da Sociedade Brasileira de Química

    Article • Química Nova, July 2017, Sociedade Brasileira de Quimica (SBQ)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  58. Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase

    Article • Nature Communications, March 2017, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  59. Chemical Composition, Antiprotozoal and Cytotoxic Activities of Indole Alkaloids and Benzofuran Neolignan of Aristolochia cordigera

    Article • Planta Medica, March 2017, Thieme Publishing Group

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  60. Friedelin Synthase from Maytenus ilicifolia: Leucine 482 Plays an Essential Role in the Production of the Most Rearranged Pentacyclic Triterpene

    Article • Scientific Reports, November 2016, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  61. Insecticidal activity of an essential oil of Tagetes patula L. (Asteraceae) on common bed bug Cimex lectularius L. and molecular docking of major compounds at the catalytic site of ClAChE1

    Article • Parasitology Research, November 2016, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  62. Biliverdin targets enolase and eukaryotic initiation factor 2 (eIF2α) to reduce the growth of intraerythrocytic development of the malaria parasite Plasmodium falciparum

    Article • Scientific Reports, February 2016, Springer Science + Business Media

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  63. Isolation of Tiliroside from Spiranthera odoratissima as Inhibitor of Trypanosoma cruzi Glyceraldehyde-3-phosphate Dehydrogenase by Using Bioactivity-Guided Fractionation

    Article • Journal of the Brazilian Chemical Society, January 2016, Sociedade Brasileira de Quimica (SBQ)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  64. HTP-OligoDesigner: An Online Primer Design Tool for High-Throughput Gene Cloning and Site-Directed Mutagenesis

    Article • Journal of Computational Biology, January 2016, Mary Ann Liebert Inc

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  65. A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K

    Article • British Journal of Pharmacology, December 2015, Wiley

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  66. The (5Z)-5-Pentacosenoic and 5-Pentacosynoic Acids Inhibit the HIV-1 Reverse Transcriptase

    Article • Lipids, September 2015, Wiley

    Doctor Nestor Manuel Carballeira, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  67. REPLY to Nanomedicine: NMB, 2015; 11:1035

    Article • Nanomedicine Nanotechnology Biology and Medicine, May 2015, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  68. Encapsulation of metalloporphyrins improves their capacity to block the viability of the human malaria parasite Plasmodium falciparum

    Article • Nanomedicine Nanotechnology Biology and Medicine, February 2015, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  69. Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor

    Article • Biochemical Journal, December 2014, Portland Press Ltd.

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  70. 2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes

    Article • Bioorganic & Medicinal Chemistry Letters, September 2014, Elsevier

    Doctor Nestor Manuel Carballeira, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  71. Pattern Recognition Techniques Applied to the Study of Leishmanial Glyceraldehyde-3-Phosphate Dehydrogenase Inhibition

    Article • International Journal of Molecular Sciences, February 2014, MDPI AG

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  72. A pharmacophore-based virtual screening approach for the discovery of Trypanosoma cruzi GAPDH inhibitors

    Article • Future Medicinal Chemistry, November 2013, Future Science

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  73. Discovery of New Inhibitors of Mycobacterium tuberculosis InhA Enzyme Using Virtual Screening and a 3D-Pharmacophore-Based Approach

    Article • Journal of Chemical Information and Modeling, August 2013, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  74. Synthetic chalcones and sulfonamides as new classes of Yersinia enterocolitica YopH tyrosine phosphatase inhibitors

    Article • European Journal of Medicinal Chemistry, June 2013, Elsevier

    Professor Hernan Terenzi, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  75. Identification of Electronic and Structural Descriptors of Adenosine Analogues Related to Inhibition of Leishmanial Glyceraldehyde-3-Phosphate Dehydrogenase

    Article • Molecules, April 2013, MDPI AG

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  76. Doenças tropicais negligenciadas: uma nova era de desafios e oportunidades

    Article • Química Nova, January 2013, FapUNIFESP (SciELO)

    Professor Luiz C Dias, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  77. Molecular Features for Antitrypanosomal Activity of Thiosemicarbazones Revealed by OPS-PLS QSAR Studies

    Article • Medicinal Chemistry, September 2012, Bentham Science Publishers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  78. Theoretical models for the antitrypanosomal activity of thiosemicarbazone derivatives

    Article • International Journal of Quantum Chemistry, June 2012, Wiley

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  79. Structure- and ligand-based drug design approaches for neglected tropical diseases

    Article • Pure and Applied Chemistry, May 2012, De Gruyter

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  80. Synthesis, Biological Evaluation, And Molecular Modeling of Chalcone Derivatives As Potent Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatases (PtpA and PtpB)

    Article • Journal of Medicinal Chemistry, December 2011, American Chemical Society (ACS)

    Professor Hernan Terenzi, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  81. Modern Drug Discovery Technologies: Opportunities and Challenges in Lead Discovery

    Article • Combinatorial Chemistry & High Throughput Screening, December 2011, Bentham Science Publishers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  82. Quantitative Structure-Activity Studies on a Series of Migrastatin Analogs as Inhibitors of Cancer Cell Metastasis

    Article • Medicinal Chemistry, May 2011, Bentham Science Publishers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  83. In silicoscreening strategies for novel inhibitors of parasitic diseases

    Article • Expert Opinion on Drug Discovery, March 2011, Informa Healthcare

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  84. Acridone alkaloids as potent inhibitors of cathepsin V

    Article • Bioorganic & Medicinal Chemistry, February 2011, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  85. Sulfonyl-hydrazones of cyclic imides derivatives as potent inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase B (PtpB)

    Article • MedChemComm, January 2011, Royal Society of Chemistry

    Professor Hernan Terenzi, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  86. Discovery of New Inhibitors of Schistosoma mansoni PNP by Pharmacophore-Based Virtual Screening

    Article • Journal of Chemical Information and Modeling, August 2010, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  87. Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: Kinetics, molecular modeling, toxicity and effect on growth

    Article • Bioorganic & Medicinal Chemistry, June 2010, Elsevier

    Professor Yossef Av-Gay, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  88. Planejamento de fármacos, biotecnologia e química medicinal: aplicações em doenças infecciosas

    Article • Estudos Avançados, January 2010, FapUNIFESP (SciELO)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  89. Quantitative structure–activity relationships for a series of inhibitors of cruzain from Trypanosoma cruzi: Molecular modeling, CoMFA and CoMSIA studies

    Article • Journal of Molecular Graphics and Modelling, August 2009, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  90. Structure-Based Drug Discovery for Tropical Diseases

    Article • Current Topics in Medicinal Chemistry, June 2009, Bentham Science Publishers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  91. Kinetic and Crystallographic Studies on Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in Complex with Iodoacetate

    Article • Letters in Drug Design & Discovery, April 2009, Bentham Science Publishers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  92. Classical and Hologram QSAR Studies on a Series of Inhibitors of Trypanosomatid Glyceraldehyde‐3‐Phosphate Dehydrogenase

    Article • QSAR & Combinatorial Science, June 2008, Wiley

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  93. Structural Basis for Selective Inhibition of Trypanosomatid Glyceraldehyde-3-Phosphate Dehydrogenase: Molecular Docking and 3D QSAR Studies

    Article • Journal of Chemical Information and Modeling, February 2008, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  94. The development of an immobilized enzyme reactor containing glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi: the effect of species' specific differences on the immobilization

    Article • The Analyst, January 2008, Royal Society of Chemistry

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  95. Virtual Screening and Its Integration with Modern Drug Design Technologies

    Article • Current Medicinal Chemistry, January 2008, Bentham Science Publishers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  96. Enzymatic Inhibitory Activity and Trypanocidal Effects of Extracts and Compounds from Siphoneugena densiflora O. Berg and Vitex polygama Cham.

    Article • Zeitschrift für Naturforschung C, January 2008, De Gruyter

    Professor Alan H Fairlamb, Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  97. Structure-activity relationships for a class of selective inhibitors of the major cysteine protease from Trypanosoma cruzi

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2008, Taylor & Francis

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  98. 2D Quantitative structure–activity relationship studies on a series of cholesteryl ester transfer protein inhibitors

    Article • Bioorganic & Medicinal Chemistry, September 2007, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  99. Classical and Hologram QSAR Studies on a Series of Tacrine Derivatives as Butyrylcholinesterase Inhibitors

    Article • Letters in Drug Design & Discovery, March 2007, Bentham Science Publishers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  100. Advances in Prodrug Design

    Article • Mini-Reviews in Medicinal Chemistry, October 2005, Bentham Science Publishers

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO

  101. Synthesis and in vitro evaluation of potential antichagasic hydroxymethylnitrofurazone (NFOH-121): a new nitrofurazone prodrug

    Article • Bioorganic & Medicinal Chemistry, November 2003, Elsevier

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO