All Stories

  1. 9‐Azahomocubane

    Article • Chemistry - A European Journal, November 2023, Wiley

    Dr Gregory Paul Savage

  2. Interrogating Aptamer Chemical Space Through Modified Nucleotide Substitution Facilitated by Enzymatic DNA Synthesis

    Article • ChemBioChem, October 2023, Wiley

    Dr Gregory Paul Savage

  3. seco-1-Azacubane-2-carboxylic acid–Amide Bond Comparison to Proline

    Article • The Journal of Organic Chemistry, August 2023, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  4. Cubane and Cyclooctatetraene Pirfenidones – Synthesis and Biological Evaluation

    Article • Asian Journal of Organic Chemistry, July 2023, Wiley

    Dr Gregory Paul Savage

  5. 1-Benzyloxy-5-phenyltetrazole derivatives highly active against androgen receptor-dependent prostate cancer cells

    Article • European Journal of Medicinal Chemistry, January 2023, Elsevier

    Dr Gregory Paul Savage

  6. Photochemical generation of the 2-azabicyclo[4.2.0]octa-4,7-diene skeleton

    Article • Australian Journal of Chemistry, August 2022, CSIRO Publishing

    Dr Gregory Paul Savage

  7. The (±)-6-Aza[1.0]triblattane Skeleton: Contraction beyond the Wilder–Culberson Ring System

    Article • Organic Letters, January 2022, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  8. A novel vitamin K derived anticoagulant tolerant to genetic variations of vitamin K epoxide reductase

    Article • Journal of Thrombosis and Haemostasis, March 2021, Elsevier

    Dr Gregory Paul Savage

  9. Enone-promoted decarboxylation of trans-4-hydroxy-l-proline in flow: a side-by-side comparison to batch

    Article • Reaction Chemistry & Engineering, January 2021, Royal Society of Chemistry

    Dr Gregory Paul Savage

  10. Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials

    Article • Journal of Medicinal Chemistry, July 2020, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  11. Evolution of abiotic cubane modified aptamers as potent biomarkers

    Article • Proceedings of the National Academy of Sciences, July 2020, Proceedings of the National Academy of Sciences

    Marcel Hollenstein, Dr Gregory Paul Savage

  12. Relay Cross Metathesis for the Iterative Construction of Terpenoids and Synthesis of a Diterpene-Benzoate Macrolide of Biogenetic Relevance to the Bromophycolides

    Article • Organic Letters, March 2020, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  13. A Relay Strategy Actuates Pre-Existing Trisubstituted Olefins in Monoterpenoids for Cross-Metathesis with Trisubstituted Alkenes

    Article • The Journal of Organic Chemistry, March 2020, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  14. Rearrangement-Free Hydroxylation of Methylcubanes by a Cytochrome P450: The Case for Dynamical Coupling of C–H Abstraction and Rebound

    Article • Journal of the American Chemical Society, November 2019, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  15. Determining the necessity of phenyl ring π-character in warfarin

    Article • Bioorganic & Medicinal Chemistry Letters, August 2019, Elsevier

    Dr Gregory Paul Savage

  16. Cyclooctatetraenes through Valence Isomerization of Cubanes: Scope and Limitations

    Article • Chemistry - A European Journal, January 2019, Wiley

    Dr Gregory Paul Savage

  17. Cyclooctatetraene: A Bioactive Cubane Paradigm Complement

    Article • Chemistry - A European Journal, January 2019, Wiley

    Dr Gregory Paul Savage

  18. A Scalable, Combined-Batch, and Continuous-Flow Synthesis of a Bio-Inspired UV-B Absorber

    Article • Australian Journal of Chemistry, January 2019, CSIRO Publishing

    Dr Gregory Paul Savage

  19. Enantioselective synthesis of (R)-2-cubylglycine including unprecedented rhodium mediated C–H insertion of cubane

    Article • Organic & Biomolecular Chemistry, January 2019, Royal Society of Chemistry

    Dr Gregory Paul Savage

  20. The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement

    Article • Organic & Biomolecular Chemistry, January 2019, Royal Society of Chemistry

    Dr Gregory Paul Savage

  21. Synthesis of the seco‐Limonoid BCD Ring System Identifies a Hsp90 Chaperon Machinery (p23) Inhibitor

    Article • Chemistry - A European Journal, December 2018, Wiley

    Dr Gregory Paul Savage

  22. Kinetic Benchmarking Reveals the Competence of Prenyl Groups in Ring-Closing Metathesis

    Article • Organic Letters, September 2017, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  23. Towards the Total Synthesis of Gedunin: Construction of the Fully Elaborated ABC Ring System

    Article • Asian Journal of Organic Chemistry, March 2017, Wiley

    Dr Gregory Paul Savage

  24. Inverse hexagonal and cubic micellar lyotropic liquid crystalline phase behaviour of novel double chain sugar-based amphiphiles

    Article • Colloids and Surfaces B Biointerfaces, March 2017, Elsevier

    Dr Gregory Paul Savage

  25. Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

    Article • Angewandte Chemie, February 2016, Wiley

    Professor Dave A Winkler, Dr Gregory Paul Savage

  26. Total synthesis of a biotinylated rocaglate: Selective targeting of the translation factors eIF4AI/II

    Article • Bioorganic & Medicinal Chemistry Letters, January 2016, Elsevier

    Dr Gregory Paul Savage

  27. Cubane: 50 Years Later

    Article • Chemical Reviews, June 2015, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  28. The direct α-C(sp3)–H functionalisation of N-aryl tetrahydroisoquinolines via an iron-catalysed aerobic nitro-Mannich reaction and continuous flow processing

    Article • Chemical Communications, January 2015, Royal Society of Chemistry

    Dr Gregory Paul Savage

  29. Unexpected Isomerisation of a Fragment Analogue During Fragment-Based Screening of HIV Integrase Catalytic Core Domain

    Article • Australian Journal of Chemistry, January 2015, CSIRO Publishing

    Dr Gregory Paul Savage

  30. Rapid Microwave-Assisted Synthesis of N-Aryl 1,2,3,4-Tetrahydroisoquinolines

    Article • Australian Journal of Chemistry, January 2015, CSIRO Publishing

    Dr Gregory Paul Savage

  31. Porous Double-Layer Polymer Tubing for the Potential Use in Heterogeneous Continuous Flow Reactions

    Article • ACS Applied Materials & Interfaces, December 2014, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  32. An Efficient Fmoc Solid-Phase Synthesis of an Amphiphile of the Neuroprotective Agent Glycyl-prolyl-glutamic Acid

    Article • Synlett, August 2014, Thieme Publishing Group

    Dr Gregory Paul Savage

  33. The search for new amphiphiles: synthesis of a modular, high-throughput library

    Article • Beilstein Journal of Organic Chemistry, July 2014, Beilstein Institut

    Dr Gregory Paul Savage

  34. The High‐Throughput Synthesis and Phase Characterisation of Amphiphiles: A Sweet Case Study

    Article • Chemistry - A European Journal, February 2014, Wiley

    Dr Gregory Paul Savage

  35. Design, synthesis and binding properties of a fluorescent α9β1/α4β1integrin antagonist and its application as anin vivoprobe for bone marrow haemopoietic stem cells

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Dr Gregory Paul Savage

  36. Benzonitrile Oxide Cycloadditions with Exocyclic Methylene Benzothiazepine Dioxides

    Article • Australian Journal of Chemistry, January 2014, CSIRO Publishing

    Dr Gregory Paul Savage

  37. What's in a Name? Moving Towards a Limited Vocabulary for Macromolecular Crystallisation

    Article • Australian Journal of Chemistry, January 2014, CSIRO Publishing

    Dr Gregory Paul Savage

  38. Pilot-Scale Production of Dimethyl 1,4-Cubanedicarboxylate

    Article • Organic Process Research & Development, November 2013, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  39. Chloroform as a Hydrogen Atom Donor in Barton Reductive Decarboxylation Reactions

    Article • The Journal of Organic Chemistry, June 2013, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  40. Synthesis of Biotinylated Episilvestrol: Highly Selective Targeting of the Translation Factors eIF4AI/II

    Article • Organic Letters, March 2013, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  41. Hyperconjugation involving strained carbon–carbon bonds. Application of the variable oxygen probe to ester and ether derivatives of cubylmethanol

    Article • Organic & Biomolecular Chemistry, January 2013, Royal Society of Chemistry

    Dr Gregory Paul Savage, Professor Jonathan White

  42. Synthesis and Self-Assembly of a Peptide - Amphiphile as a Drug Delivery Vehicle

    Article • Australian Journal of Chemistry, January 2013, CSIRO Publishing

    Dr Gregory Paul Savage

  43. N-Aryl Atropisomerism Induces Facial Selectivity in Benzonitrile Oxide Cycloadditions with Exocyclic Methylene Benzosultams

    Article • Australian Journal of Chemistry, January 2013, CSIRO Publishing

    Dr Gregory Paul Savage

  44. A Multi-Step Continuous Flow Process for the N-Demethylation of Alkaloids

    Article • Australian Journal of Chemistry, January 2013, CSIRO Publishing

    Dr Gregory Paul Savage

  45. Construction of the CSIRO Fragment Library

    Article • Australian Journal of Chemistry, January 2013, CSIRO Publishing

    Dr Gregory Paul Savage

  46. Evaluation of a chiral cubane-based Schiff base ligand in asymmetric catalysis reactions

    Article • Beilstein Journal of Organic Chemistry, October 2012, Beilstein Institut

    Dr Gregory Paul Savage

  47. Click-Chemistry as a Mix-and-Match Kit for Amphiphile Synthesis

    Article • ACS Combinatorial Science, September 2012, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  48. N‐Alkylsulfonylimines as Dipolarophiles in Cycloaddition Reactions

    Article • Chemistry - An Asian Journal, September 2012, Wiley

    Dr Gregory Paul Savage

  49. Total Synthesis of 2‴,5‴-Diepisilvestrol and Its C1‴ Epimer: Key Structure Activity Relationships at C1‴ and C2‴

    Article • Journal of Natural Products, July 2012, American Chemical Society (ACS)

    Dr Gregory Paul Savage, Professor Jonathan White

  50. Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design

    Article • PLoS ONE, July 2012, PLOS

    Dr Gregory Paul Savage

  51. Aryl nitrile oxide cycloaddition reactions in the presence of pinacol boronic acid ester

    Article • Beilstein Journal of Organic Chemistry, April 2012, Beilstein Institut

    Dr Gregory Paul Savage

  52. Facial selectivity induced by N-aryl atropisomerism in benzonitrile oxide cycloadditions with 4-methylene-2-oxazolidinones

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Dr Gregory Paul Savage

  53. Cage opening and rearrangement of 1-iodocubane-4-carboxaldehyde

    Article • Tetrahedron Letters, November 2011, Elsevier

    Dr Gregory Paul Savage

  54. Atropisomerism-Induced Facial Selectivity in Nitrile Oxide Cycloadditions with 5-Methylenehydantoins

    Article • The Journal of Organic Chemistry, July 2011, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  55. A Concise Route to Dihydrobenzo[b]furans: Formal Total Synthesis of (+)-Lithospermic Acid

    Article • Organic Letters, June 2011, American Chemical Society (ACS)

    Dr Gregory Paul Savage, Associate Professor Mark J Coster

  56. Reducing the Cost, Smell, and Toxicity of the Barton Reductive Decarboxylation: Chloroform as the Hydrogen Atom Source

    Article • Organic Letters, March 2011, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  57. Studies on the Synthesis of cis-4-Hydroxy-L-proline

    Article • Australian Journal of Chemistry, January 2011, CSIRO Publishing

    Dr Gregory Paul Savage

  58. Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design

    Article • Antiviral Chemistry and Chemotherapy, January 2011, International Medical Press

    Dr Gregory Paul Savage, Dr Thomas S Peat

  59. Nitrile Oxide 1,3-Dipolar Cycloaddition by Dehydration of Nitromethane Derivatives Under Continuous Flow Conditions

    Article • Australian Journal of Chemistry, January 2011, CSIRO Publishing

    Dr Gregory Paul Savage

  60. Spiro Isoxazolines via Nitrile Oxide 1,3-Dipolar Cycloaddition Reactions

    Article • Current Organic Chemistry, August 2010, Bentham Science Publishers

    Dr Gregory Paul Savage

  61. Thermochemical properties of iodinated cubane derivatives

    Article • Thermochimica Acta, February 2010, Elsevier

    Dr Gregory Paul Savage

  62. Cubane: A New NMR Internal Standard

    Article • Australian Journal of Chemistry, January 2010, CSIRO Publishing

    Dr Gregory Paul Savage

  63. Spiroheterocycles via Regioselective Cycloaddition Reactions of Nitrile Oxides with 5-Methylene-1 H -pyrrol-2(5 H )-ones

    Article • Australian Journal of Chemistry, January 2010, CSIRO Publishing

    Dr Gregory Paul Savage

  64. Synthesis of a Novel Chiral Cubane-Based Schiff Base Ligand and Its Application in Asymmetric Nitro-Aldol (Henry) Reactions

    Article • Synthesis, October 2009, Thieme Publishing Group

    Dr Gregory Paul Savage

  65. Total Synthesis of the Potent Anticancer Aglaia Metabolites (−)-Silvestrol and (−)-Episilvestrol and the Active Analogue (−)-4′-Desmethoxyepisilvestrol

    Article • Journal of the American Chemical Society, January 2009, American Chemical Society (ACS)

    Dr Gregory Paul Savage

  66. Free-Radical Polymerization and Ring-Expansion of a Cubane Acrylate: a Unique Low-Shrink Polymer

    Article • Australian Journal of Chemistry, January 2009, CSIRO Publishing

    Dr Gregory Paul Savage

  67. Regioselective 1,3-Dipolar Cycloaddition Reactions of 4-Methylene-2-oxazolidinones with Benzonitrile Oxide

    Article • Australian Journal of Chemistry, January 2008, CSIRO Publishing

    Dr Gregory Paul Savage

  68. Nitrile Oxide Cycloaddition Chemistry Using Benzotriazole as a Steric Auxiliary.

    Article • ChemInform, May 2006, Wiley

    Dr Gregory Paul Savage

  69. Methyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptors

    Article • Bioorganic & Medicinal Chemistry, July 2005, Elsevier

    Dr Gregory Paul Savage

  70. An enantioselective total synthesis of the stilbenolignan (−)-aiphanol and the determination of its absolute stereochemistry

    Article • Tetrahedron Asymmetry, May 2005, Elsevier

    Dr Gregory Paul Savage

  71. Nitrile Oxide Cycloaddition Chemistry Using Benzotriazole as a Steric Auxiliary

    Article • Australian Journal of Chemistry, January 2005, CSIRO Publishing

    Dr Gregory Paul Savage, Professor Dave A Winkler

  72. Synthesis of tricyclic analogues of methyllycaconitine using ring closing metathesis to append a B ring to an AE azabicyclic fragment

    Article • Organic & Biomolecular Chemistry, January 2004, Royal Society of Chemistry

    Dr Gregory Paul Savage

  73. Convergent synthesis and preliminary biological evaluations of the stilbenolignan (±)-aiphanol and various congeners

    Article • Organic & Biomolecular Chemistry, January 2003, Royal Society of Chemistry

    Dr Gregory Paul Savage

  74. ChemInform Abstract: Electrochemical and Yeast‐Catalyzed Ring‐Opening of Isoxazoles in the Synthesis of Analogues of the Herbicide Grasp®.

    Article • ChemInform, December 2001, Wiley

    Dr Gregory Paul Savage

  75. Electrochemical and yeast-catalysed ring-opening of isoxazoles in the synthesis of analogues of the herbicide Grasp ®

    Article • Journal of the Chemical Society Perkin Transactions 1, January 2001, Royal Society of Chemistry

    Dr Gregory Paul Savage

  76. Dipolar Cycloaddition Reactions of Nitrilimines

    Article • Australian Journal of Chemistry, January 1998, CSIRO Publishing

    Dr Gregory Paul Savage

  77. Exploiting the 1,3-dithiane of 2-oxopropanenitrile oxide to limit competing dimerization in 1,3-dipolar cycloaddition reactions

    Article • Tetrahedron Letters, March 1997, Elsevier

    Dr Gregory Paul Savage

  78. Perfluorohexane As a Novel Reaction Medium For Bromination Reactions

    Article • Synthetic Communications, April 1995, Taylor & Francis

    Dr Gregory Paul Savage

  79. Aryl nitrile oxide cycloaddition reactions in the presence of baker's yeast and β-cyclodextrin

    Article • Tetrahedron Letters, January 1995, Elsevier

    Dr Gregory Paul Savage

  80. Synthesis of unsymmetrically 4-substituted 2,2′-bipyridines

    Article • Tetrahedron Letters, January 1995, Elsevier

    Dr Gregory Paul Savage

  81. Reversal of regiochemistry in the synthesis of isoxazoles by nitrile oxide cycloadditions

    Article • Tetrahedron Letters, May 1994, Elsevier

    Dr Gregory Paul Savage

  82. Yeast-catalysed reductive ring-opening of isoxazoles

    Article • Journal of the Chemical Society Chemical Communications, January 1994, Royal Society of Chemistry

    Dr Gregory Paul Savage

  83. Asymmetric Synthesis of a Homochiral D2-Isoxazoline Amino Acid Derivative

    Article • Heterocycles, January 1994, CLOCKSS Archive

    Dr Gregory Paul Savage

  84. Cycloaddition Reactions of Nitrile Oxides with Alkenes

    Article • January 1994, Elsevier

    Dr Gregory Paul Savage