All Stories

  1. 9‐Azahomocubane
  2. Interrogating Aptamer Chemical Space Through Modified Nucleotide Substitution Facilitated by Enzymatic DNA Synthesis
  3. seco-1-Azacubane-2-carboxylic acid–Amide Bond Comparison to Proline
  4. Cubane and Cyclooctatetraene Pirfenidones – Synthesis and Biological Evaluation
  5. 1-Benzyloxy-5-phenyltetrazole derivatives highly active against androgen receptor-dependent prostate cancer cells
  6. Photochemical generation of the 2-azabicyclo[4.2.0]octa-4,7-diene skeleton
  7. The (±)-6-Aza[1.0]triblattane Skeleton: Contraction beyond the Wilder–Culberson Ring System
  8. A novel vitamin K derived anticoagulant tolerant to genetic variations of vitamin K epoxide reductase
  9. Enone-promoted decarboxylation of trans-4-hydroxy-l-proline in flow: a side-by-side comparison to batch
  10. Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials
  11. Evolution of abiotic cubane modified aptamers as potent biomarkers
  12. Relay Cross Metathesis for the Iterative Construction of Terpenoids and Synthesis of a Diterpene-Benzoate Macrolide of Biogenetic Relevance to the Bromophycolides
  13. A Relay Strategy Actuates Pre-Existing Trisubstituted Olefins in Monoterpenoids for Cross-Metathesis with Trisubstituted Alkenes
  14. Rearrangement-Free Hydroxylation of Methylcubanes by a Cytochrome P450: The Case for Dynamical Coupling of C–H Abstraction and Rebound
  15. Determining the necessity of phenyl ring π-character in warfarin
  16. Cyclooctatetraenes through Valence Isomerization of Cubanes: Scope and Limitations
  17. Cyclooctatetraene: A Bioactive Cubane Paradigm Complement
  18. A Scalable, Combined-Batch, and Continuous-Flow Synthesis of a Bio-Inspired UV-B Absorber
  19. Enantioselective synthesis of (R)-2-cubylglycine including unprecedented rhodium mediated C–H insertion of cubane
  20. The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement
  21. Synthesis of the seco‐Limonoid BCD Ring System Identifies a Hsp90 Chaperon Machinery (p23) Inhibitor
  22. Kinetic Benchmarking Reveals the Competence of Prenyl Groups in Ring-Closing Metathesis
  23. Towards the Total Synthesis of Gedunin: Construction of the Fully Elaborated ABC Ring System
  24. Inverse hexagonal and cubic micellar lyotropic liquid crystalline phase behaviour of novel double chain sugar-based amphiphiles
  25. Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere
  26. Total synthesis of a biotinylated rocaglate: Selective targeting of the translation factors eIF4AI/II
  27. Cubane: 50 Years Later
  28. The direct α-C(sp3)–H functionalisation of N-aryl tetrahydroisoquinolines via an iron-catalysed aerobic nitro-Mannich reaction and continuous flow processing
  29. Unexpected Isomerisation of a Fragment Analogue During Fragment-Based Screening of HIV Integrase Catalytic Core Domain
  30. Rapid Microwave-Assisted Synthesis of N-Aryl 1,2,3,4-Tetrahydroisoquinolines
  31. Porous Double-Layer Polymer Tubing for the Potential Use in Heterogeneous Continuous Flow Reactions
  32. An Efficient Fmoc Solid-Phase Synthesis of an Amphiphile of the Neuroprotective Agent Glycyl-prolyl-glutamic Acid
  33. The search for new amphiphiles: synthesis of a modular, high-throughput library
  34. The High‐Throughput Synthesis and Phase Characterisation of Amphiphiles: A Sweet Case Study
  35. Design, synthesis and binding properties of a fluorescent α9β1/α4β1integrin antagonist and its application as anin vivoprobe for bone marrow haemopoietic stem cells
  36. Benzonitrile Oxide Cycloadditions with Exocyclic Methylene Benzothiazepine Dioxides
  37. What's in a Name? Moving Towards a Limited Vocabulary for Macromolecular Crystallisation
  38. Pilot-Scale Production of Dimethyl 1,4-Cubanedicarboxylate
  39. Chloroform as a Hydrogen Atom Donor in Barton Reductive Decarboxylation Reactions
  40. Synthesis of Biotinylated Episilvestrol: Highly Selective Targeting of the Translation Factors eIF4AI/II
  41. Hyperconjugation involving strained carbon–carbon bonds. Application of the variable oxygen probe to ester and ether derivatives of cubylmethanol
  42. Synthesis and Self-Assembly of a Peptide - Amphiphile as a Drug Delivery Vehicle
  43. N-Aryl Atropisomerism Induces Facial Selectivity in Benzonitrile Oxide Cycloadditions with Exocyclic Methylene Benzosultams
  44. A Multi-Step Continuous Flow Process for the N-Demethylation of Alkaloids
  45. Construction of the CSIRO Fragment Library
  46. Evaluation of a chiral cubane-based Schiff base ligand in asymmetric catalysis reactions
  47. Click-Chemistry as a Mix-and-Match Kit for Amphiphile Synthesis
  48. N‐Alkylsulfonylimines as Dipolarophiles in Cycloaddition Reactions
  49. Total Synthesis of 2‴,5‴-Diepisilvestrol and Its C1‴ Epimer: Key Structure Activity Relationships at C1‴ and C2‴
  50. Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design
  51. Aryl nitrile oxide cycloaddition reactions in the presence of pinacol boronic acid ester
  52. Facial selectivity induced by N-aryl atropisomerism in benzonitrile oxide cycloadditions with 4-methylene-2-oxazolidinones
  53. Cage opening and rearrangement of 1-iodocubane-4-carboxaldehyde
  54. Atropisomerism-Induced Facial Selectivity in Nitrile Oxide Cycloadditions with 5-Methylenehydantoins
  55. A Concise Route to Dihydrobenzo[b]furans: Formal Total Synthesis of (+)-Lithospermic Acid
  56. Reducing the Cost, Smell, and Toxicity of the Barton Reductive Decarboxylation: Chloroform as the Hydrogen Atom Source
  57. Studies on the Synthesis of cis-4-Hydroxy-L-proline
  58. Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design
  59. Nitrile Oxide 1,3-Dipolar Cycloaddition by Dehydration of Nitromethane Derivatives Under Continuous Flow Conditions
  60. Spiro Isoxazolines via Nitrile Oxide 1,3-Dipolar Cycloaddition Reactions
  61. Thermochemical properties of iodinated cubane derivatives
  62. Cubane: A New NMR Internal Standard
  63. Spiroheterocycles via Regioselective Cycloaddition Reactions of Nitrile Oxides with 5-Methylene-1 H -pyrrol-2(5 H )-ones
  64. Synthesis of a Novel Chiral Cubane-Based Schiff Base Ligand and Its Application in Asymmetric Nitro-Aldol (Henry) Reactions
  65. Total Synthesis of the Potent Anticancer Aglaia Metabolites (−)-Silvestrol and (−)-Episilvestrol and the Active Analogue (−)-4′-Desmethoxyepisilvestrol
  66. Free-Radical Polymerization and Ring-Expansion of a Cubane Acrylate: a Unique Low-Shrink Polymer
  67. Regioselective 1,3-Dipolar Cycloaddition Reactions of 4-Methylene-2-oxazolidinones with Benzonitrile Oxide
  68. Nitrile Oxide Cycloaddition Chemistry Using Benzotriazole as a Steric Auxiliary.
  69. Methyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptors
  70. An enantioselective total synthesis of the stilbenolignan (−)-aiphanol and the determination of its absolute stereochemistry
  71. Nitrile Oxide Cycloaddition Chemistry Using Benzotriazole as a Steric Auxiliary
  72. Synthesis of tricyclic analogues of methyllycaconitine using ring closing metathesis to append a B ring to an AE azabicyclic fragment
  73. Convergent synthesis and preliminary biological evaluations of the stilbenolignan (±)-aiphanol and various congeners
  74. ChemInform Abstract: Electrochemical and Yeast‐Catalyzed Ring‐Opening of Isoxazoles in the Synthesis of Analogues of the Herbicide Grasp®.
  75. Electrochemical and yeast-catalysed ring-opening of isoxazoles in the synthesis of analogues of the herbicide Grasp ®
  76. Dipolar Cycloaddition Reactions of Nitrilimines
  77. Exploiting the 1,3-dithiane of 2-oxopropanenitrile oxide to limit competing dimerization in 1,3-dipolar cycloaddition reactions
  78. Perfluorohexane As a Novel Reaction Medium For Bromination Reactions
  79. Aryl nitrile oxide cycloaddition reactions in the presence of baker's yeast and β-cyclodextrin
  80. Synthesis of unsymmetrically 4-substituted 2,2′-bipyridines
  81. Reversal of regiochemistry in the synthesis of isoxazoles by nitrile oxide cycloadditions
  82. Yeast-catalysed reductive ring-opening of isoxazoles
  83. Asymmetric Synthesis of a Homochiral D2-Isoxazoline Amino Acid Derivative
  84. Cycloaddition Reactions of Nitrile Oxides with Alkenes