All Stories

  1. Dissecting the Interaction Domains of SARS-CoV-2 Nucleocapsid Protein and Human RNA Helicase DDX3X and Search for Potential Inhibitors
  2. Post-Translational Modifications Remodel Proteome-Wide Ligandability
  3. Light-mediated activation/deactivation control and in vitro ADME-Tox profiling of a donepezil-like Dual AChE/MAO-B Inhibitor
  4. Corrigendum to “Applying molecular hybridization to design a new class of pyrazolo[3,4-d] pyrimidines as Src inhibitors active in hepatocellular carcinoma” [Eur. J. Med. Chem. 280 (2024) 116929]
  5. Morita–Baylis–Hillman Adduct Chemistry as a Tool for the Design of Lysine-Targeted Covalent Ligands
  6. A Standardized Extract of Zingiber officinale Roscoe Regulates Clinical and Biological Outcomes in Two Different EAE Mouse Models
  7. Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma
  8. Hylotelephium telephium (L) H. Ohba leaves juice improves herpetic lesions: new findings from in vitro investigations
  9. Author Correction: Enhanced mapping of small-molecule binding sites in cells
  10. Enhanced mapping of small-molecule binding sites in cells
  11. Benzenesulfonamide decorated dihydropyrimidin(thi)ones: carbonic anhydrase profiling and antiproliferative activity
  12. Consensus screening for a challenging target: the quest for P-glycoprotein inhibitors
  13. Consensus screening for a challenging target: the quest for P-glycoprotein inhibitors
  14. Helichrysum stoechas (L.) Moench reduces body weight gain and modulates mood disorders via inhibition of silent information regulator 1 (SIRT1) by arzanol
  15. Antiviral Activity of Cannabidiolic Acid and Its Methyl Ester against SARS-CoV-2
  16. Effect of in vitro simulated digestion on the anti- Helicobacter Pylori activity of different Propolis extracts
  17. Zingiberene, a non-zinc-binding class I HDAC inhibitor: A novel strategy for the management of neuropathic pain
  18. A Novel Perilla frutescens (L.) Britton Cell-Derived Phytocomplex Regulates Keratinocytes Inflammatory Cascade and Barrier Function and Preserves Vaginal Mucosal Integrity In Vivo
  19. Cannabidiol‐rich non‐psychotropic Cannabis sativa L. oils attenuate peripheral neuropathy symptoms by regulation of CB2‐mediated microglial neuroinflammation
  20. Anti-inflammatory activity of a fixed combination of probiotics and herbal extract in an in-vitro model of intestinal inflammation by stimulating Caco-2 cells with LPS-conditioned THP-1 cells medium
  21. Investigation on the neuroprotective effect of a cannabidiol-enriched non-psychotropic Cannabis sativa L. extract in an in vitro model of excitotoxicity
  22. Quinolines and Oxazino-quinoline Derivatives as Small Molecule GLI1 Inhibitors Identified by Virtual Screening
  23. Survey on the Recent Advances in 4-Hydroxyphenylpyruvate Dioxygenase (HPPD) Inhibition by Diketone and Triketone Derivatives and Congeneric Compounds: Structural Analysis of HPPD/Inhibitor Complexes and Structure–Activity Relationship Considerations
  24. Non‐psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors‐, endocannabinoids‐, and NF‐κB‐mediated signaling
  25. Recent research results have converted gp120 binders to a therapeutic option for the treatment of HIV-1 infection. A medicinal chemistry point of view
  26. In Vitro Cell Culture of Rhus coriaria L.: A Standardized Phytocomplex Rich of Gallic Acid Derivatives with Antioxidant and Skin Repair Activity
  27. The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme
  28. Effects of in vitro simulated digestion on the antioxidant activity of different Camellia sinensis (L.) Kuntze leaves extracts
  29. A honokiol-enriched Magnolia officinalis Rehder & E.H. Wilson. bark extract possesses anxiolytic-like activity with neuroprotective effect through the modulation of CB1 receptor
  30. FFAR1/GPR40: One target, different binding sites, many agonists, no drugs, but a continuous and unprofitable tug-of-war between ligand lipophilicity, activity, and toxicity
  31. Cannabidiol Isolated From Cannabis sativa L. Protects Intestinal Barrier From In Vitro Inflammation and Oxidative Stress
  32. Pinocembrin and its linolenoyl ester derivative induce wound healing activity in HaCaT cell line potentially involving a GPR120/FFA4 mediated pathway
  33. Zingiber officinale Roscoe rhizome extract alleviates neuropathic pain by inhibiting neuroinflammation in mice
  34. Novel Therapeutic Approach for the Management of Mood Disorders: In Vivo and In Vitro Effect of a Combination of L-Theanine, Melissa officinalis L. and Magnolia officinalis Rehder & E.H. Wilson
  35. Mantonico and Pecorello Grape Seed Extracts: Chemical Characterization and Evaluation of In Vitro Wound-Healing and Anti-Inflammatory Activities
  36. Rhodiola rosea L. modulates inflammatory processes in a CRH-activated BV2 cell model
  37. Sangiovese cv Pomace Seeds Extract-Fortified Kefir Exerts Anti-Inflammatory Activity in an In Vitro Model of Intestinal Epithelium Using Caco-2 Cells
  38. Cannabidiol-enriched Cannabis sativa L. extract modulates inflammatory-induced human peripheral mononuclear cells response
  39. Anti-inflammatory effect of euro-asiatic poplar propolis compared to flurbiprofen
  40. Medicinal Chemistry of Neglected and Tropical Diseases
  41. Quercetin‐3‐Oleate Contributes to Skin Wound Healing Targeting FFA1/GPR40
  42. Cannabis sativa L. Constituents and Their Role in Neuroinflammation
  43. Copaifera langsdorffii Desf.: in vitro investigation on anti-Helicobacter pylori and anti-inflammatory activities of oleoresin and fruit methanolic extract
  44. Comparison of the in vitro wound healing activity of diffetent Calabrian honey
  45. Characterization and in vitro antiradical and wound healing activity of five Italian Sedum species
  46. Evaluation of the activity of Curcuma longa and Boswellia serrata extracts in a model of IBD
  47. Probiotics and herbal extract protect intestinal barrier from in vitro inflammatory stimulation
  48. Effects of Boswellia serrata Roxb. and Curcuma longa L. in an In Vitro Intestinal Inflammation Model Using Immune Cells and Caco-2
  49. Medicinal plants with evidence-based effectiveness in the management of diabetes
  50. Phytotherapy in the Management of Diabetes: A Review
  51. A Fixed Combination of Probiotics and Herbal Extracts Attenuates Intestinal Barrier Dysfunction from Inflammatory Stress
  52. Phytotherapy in the Management of Diabetes: A Review
  53. Ethnobotanical study of medicinal plants used for wound healing in Greece and Italy
  54. Molecular interaction between Serenoa repens constituents and the active site of 5alpha-reductase
  55. Normative overview of the herbal products market in Italy
  56. Herbal Products in Italy: The Thin Line between Phytotherapy, Nutrition and Parapharmaceuticals; a Normative Overview of the Fastest Growing Market in Europe
  57. Effectiveness of 5-Pyrrolidone-2-carboxylic Acid and Copper Sulfate Pentahydrate Association against Drug Resistant Staphylococcus Strains