All Stories

  1. RNA Sequencing Reveals Diverse Functions of Amniotic Fluid Neutrophils and Monocytes/Macrophages in Intra-Amniotic Infection

    Article • Journal of Innate Immunity, November 2020, Karger Publishers

    Nardhy Gomez-Lopez

  2. Pregnancy-specific transcriptional changes upon endotoxin exposure in mice

    Article • Journal of Perinatal Medicine, August 2020, De Gruyter

    Nardhy Gomez-Lopez

  3. Cellular immune responses in amniotic fluid of women with preterm prelabor rupture of membranes

    Article • Journal of Perinatal Medicine, March 2020, De Gruyter

    Dr Roberto Romero, Nardhy Gomez-Lopez

  4. Microbial burden and inflammasome activation in amniotic fluid of patients with preterm prelabor rupture of membranes

    Article • Journal of Perinatal Medicine, January 2020, De Gruyter

    Nardhy Gomez-Lopez, Dr Roberto Romero

  5. Cellular immune responses in amniotic fluid of women with preterm clinical chorioamnionitis

    Article • Inflammation Research, January 2020, Springer Science + Business Media

    Nardhy Gomez-Lopez

  6. Preterm labor is characterized by a high abundance of amniotic fluid prostaglandins in patients with intra-amniotic infection or sterile intra-amniotic inflammation

    Article • The Journal of Maternal-Fetal & Neonatal Medicine, December 2019, Taylor & Francis

    Nardhy Gomez-Lopez

  7. No consistent evidence for microbiota in murine placental and fetal tissues

    Article • December 2019, Cold Spring Harbor Laboratory Press

    Nardhy Gomez-Lopez

  8. Single cell transcriptional signatures of the human placenta in term and preterm parturition

    Article • eLife, December 2019, eLife

    Nardhy Gomez-Lopez

  9. Inflammasomes: Their Role in Normal and Complicated Pregnancies

    Article • The Journal of Immunology, November 2019, The American Association of Immunologists

    Nardhy Gomez-Lopez

  10. Gasdermin D: Evidence of pyroptosis in spontaneous preterm labor with sterile intra‐amniotic inflammation or intra‐amniotic infection

    Article • American Journal of Reproductive Immunology, September 2019, Wiley

    Nardhy Gomez-Lopez

  11. The origin of amniotic fluid monocytes/macrophages in women with intra-amniotic inflammation or infection

    Article • Journal of Perinatal Medicine, September 2019, De Gruyter

    Nardhy Gomez-Lopez, Dr Roberto Romero

  12. Fetal T Cell Activation in the Amniotic Cavity during Preterm Labor: A Potential Mechanism for a Subset of Idiopathic Preterm Birth

    Article • The Journal of Immunology, September 2019, The American Association of Immunologists

    Nardhy Gomez-Lopez

  13. Cellular immune responses in amniotic fluid of women with preterm labor and intra‐amniotic infection or intra‐amniotic inflammation

    Article • American Journal of Reproductive Immunology, September 2019, Wiley

    Nardhy Gomez-Lopez

  14. Single Cell Transcriptional Signatures of the Human Placenta in Term and Preterm Parturition

    Article • August 2019, Cold Spring Harbor Laboratory Press

    Nardhy Gomez-Lopez

  15. Separating the signal from the noise in metagenomic cell-free DNA sequencing

    Article • August 2019, Cold Spring Harbor Laboratory Press

    Nardhy Gomez-Lopez

  16. Exhausted and Senescent T Cells at the Maternal-Fetal Interface in Preterm and Term Labor

    Article • Journal of Immunology Research, May 2019, Hindawi Publishing Corporation

    Dr Roberto Romero, Nardhy Gomez-Lopez

  17. Gasdermin D: in vivo evidence of pyroptosis in spontaneous labor at term

    Article • The Journal of Maternal-Fetal & Neonatal Medicine, May 2019, Taylor & Francis

    Nardhy Gomez-Lopez, Dr Roberto Romero

  18. Clinical chorioamnionitis at term IX: in vivo evidence of intra-amniotic inflammasome activation

    Article • Journal of Perinatal Medicine, April 2019, De Gruyter

    Nardhy Gomez-Lopez, Dr Roberto Romero

  19. Human β-defensin-3 participates in intra-amniotic host defense in women with labor at term, spontaneous preterm labor and intact membranes, and preterm prelabor rupture of membranes

    Article • The Journal of Maternal-Fetal & Neonatal Medicine, April 2019, Taylor & Francis

    Dr Roberto Romero, Nardhy Gomez-Lopez

  20. Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth and adverse neonatal outcomes†

    Article • Biology of Reproduction, December 2018, Oxford University Press (OUP)

    Nardhy Gomez-Lopez

  21. Inflammation-Induced Intra-Amniotic inflammation induces preterm birth by Activating the NLRP3 inflammasome†

    Article • Biology of Reproduction, December 2018, Oxford University Press (OUP)

    Nardhy Gomez-Lopez

  22. Cover

    Article • American Journal of Reproductive Immunology, October 2018, Wiley

    Nardhy Gomez-Lopez

  23. Inflammasome activation during spontaneous preterm labor with intra-amniotic infection or sterile intra-amniotic inflammation

    Article • American Journal of Reproductive Immunology, September 2018, Wiley

    Nardhy Gomez-Lopez

  24. Human β-defensin-1: A natural antimicrobial peptide present in amniotic fluid that is increased in spontaneous preterm labor with intra-amniotic infection

    Article • American Journal of Reproductive Immunology, August 2018, Wiley

    Nardhy Gomez-Lopez

  25. Cover

    Article • American Journal of Reproductive Immunology, June 2018, Wiley

    Nardhy Gomez-Lopez

  26. Extracellular vesicles generated by placental tissues ex vivo: A transport system for immune mediators and growth factors

    Article • American Journal of Reproductive Immunology, May 2018, Wiley

    Nardhy Gomez-Lopez

  27. Cover

    Article • American Journal of Reproductive Immunology, March 2018, Wiley

    Nardhy Gomez-Lopez

  28. The immunophenotype of amniotic fluid leukocytes in normal and complicated pregnancies

    Article • American Journal of Reproductive Immunology, March 2018, Wiley

    Nardhy Gomez-Lopez

  29. Innate lymphoid cells at the human maternal-fetal interface in spontaneous preterm labor

    Article • American Journal of Reproductive Immunology, February 2018, Wiley

    Nardhy Gomez-Lopez

  30. CD71+ erythroid cells from neonates born to women with preterm labor regulate cytokine and cellular responses

    Article • Journal of Leukocyte Biology, February 2018, Wiley

    Nardhy Gomez-Lopez

  31. In vivo evidence of inflammasome activation during spontaneous labor at term

    Article • The Journal of Maternal-Fetal & Neonatal Medicine, January 2018, Taylor & Francis

    Nardhy Gomez-Lopez, Dr Roberto Romero

  32. Preterm labor in the absence of acute histologic chorioamnionitis is characterized by cellular senescence of the chorioamniotic membranes

    Article • American Journal of Obstetrics and Gynecology, November 2017, Elsevier

    Nardhy Gomez-Lopez

  33. Are amniotic fluid neutrophils in women with intraamniotic infection and/or inflammation of fetal or maternal origin?

    Article • American Journal of Obstetrics and Gynecology, September 2017, Elsevier

    Nardhy Gomez-Lopez

  34. Mutations in fetal genes involved in innate immunity and host defense against microbes increase risk of preterm premature rupture of membranes (PPROM)

    Article • Molecular Genetics & Genomic Medicine, August 2017, Wiley

    Nardhy Gomez-Lopez

  35. Amniotic fluid neutrophils can phagocytize bacteria: A mechanism for microbial killing in the amniotic cavity

    Article • American Journal of Reproductive Immunology, July 2017, Wiley

    Nardhy Gomez-Lopez

  36. The cytokine network in women with an asymptomatic short cervix and the risk of preterm delivery

    Article • American Journal of Reproductive Immunology, June 2017, Wiley

    Nardhy Gomez-Lopez

  37. Twenty-four percent of patients with clinical chorioamnionitis in preterm gestations have no evidence of either culture-proven intraamniotic infection or intraamniotic inflammation

    Article • American Journal of Obstetrics and Gynecology, June 2017, Elsevier

    Nardhy Gomez-Lopez

  38. In vivo activation of invariant natural killer T cells induces systemic and local alterations in T-cell subsets prior to preterm birth

    Article • Clinical & Experimental Immunology, May 2017, Wiley

    Nardhy Gomez-Lopez

  39. Rosiglitazone Regulates TLR4 and Rescues HO-1 and NRF2 Expression in Myometrial and Decidual Macrophages in Inflammation-Induced Preterm Birth

    Article • Reproductive Sciences, March 2017, SAGE Publications

    Nardhy Gomez-Lopez

  40. Inflammasome assembly in the chorioamniotic membranes during spontaneous labor at term

    Article • American Journal of Reproductive Immunology, February 2017, Wiley

    Nardhy Gomez-Lopez

  41. Cover

    Article • American Journal of Reproductive Immunology, February 2017, Wiley

    Nardhy Gomez-Lopez

  42. A Role for the Inflammasome in Spontaneous Preterm Labor With Acute Histologic Chorioamnionitis

    Article • Reproductive Sciences, January 2017, SAGE Publications

    Dr Roberto Romero, Nardhy Gomez-Lopez

  43. Neutrophil extracellular traps in acute chorioamnionitis: A mechanism of host defense

    Article • American Journal of Reproductive Immunology, January 2017, Wiley

    Nardhy Gomez-Lopez

  44. Clinical chorioamnionitis at term VII: the amniotic fluid cellular immune response

    Article • Journal of Perinatal Medicine, January 2017, De Gruyter

    Nardhy Gomez-Lopez

  45. Neutrophil Extracellular Traps in the Amniotic Cavity of Women with Intra-Amniotic Infection: A New Mechanism of Host Defense

    Article • Reproductive Sciences, November 2016, SAGE Publications

    Dr Roberto Romero, Nardhy Gomez-Lopez

  46. A Role for the Inflammasome in Spontaneous Labor at Term with Acute Histologic Chorioamnionitis

    Article • Reproductive Sciences, November 2016, SAGE Publications

    Dr Roberto Romero, Nardhy Gomez-Lopez

  47. In vivo T-cell activation by a monoclonal αCD3ε antibody induces preterm labor and birth

    Article • American Journal of Reproductive Immunology, September 2016, Wiley

    Nardhy Gomez-Lopez

  48. Umbilical cord CD71+ erythroid cells are reduced in neonates born to women in spontaneous preterm labor

    Article • American Journal of Reproductive Immunology, September 2016, Wiley

    Nardhy Gomez-Lopez

  49. Folate receptor targeted three-layered micelles and hydrogels for gene delivery to activated macrophages

    Article • Journal of Controlled Release, August 2016, Elsevier

    Nardhy Gomez-Lopez

  50. Innate Lymphoid Cells Type 3 are Increased in Spontaneous Preterm Labor

    Article • Journal of Reproductive Immunology, June 2016, Elsevier

    Nardhy Gomez-Lopez

  51. Innate lymphoid cells type 3 are increased in spontaneous preterm labor

    Article • Journal of Reproductive Immunology, June 2016, Elsevier

    Nardhy Gomez-Lopez

  52. Human Chorionic Gonadotropin Has Anti-Inflammatory Effects at the Maternal-Fetal Interface and Prevents Endotoxin-Induced Preterm Birth, but Causes Dystocia and Fetal Compromise in Mice

    Article • Biology of Reproduction, May 2016, Society for the Study of Reproduction

    Nardhy Gomez-Lopez

  53. A Role for the Inflammasome in Spontaneous Labor at Term

    Article • American Journal of Reproductive Immunology, March 2016, Wiley

    Nardhy Gomez-Lopez

  54. An M1-like Macrophage Polarization in Decidual Tissue during Spontaneous Preterm Labor That Is Attenuated by Rosiglitazone Treatment

    Article • The Journal of Immunology, February 2016, The American Association of Immunologists

    Nardhy Gomez-Lopez

  55. Development and Validation of a Rex1-RFP Potency Activity Reporter Assay That Quantifies Stress-Forced Potency Loss in Mouse Embryonic Stem Cells

    Article • Stem Cells and Development, February 2016, Mary Ann Liebert Inc

    Nardhy Gomez-Lopez

  56. Invariant NKT Cell Activation Induces Late Preterm Birth That Is Attenuated by Rosiglitazone

    Article • The Journal of Immunology, January 2016, The American Association of Immunologists

    Nardhy Gomez-Lopez

  57. Intra-Amniotic Administration of HMGB1 Induces Spontaneous Preterm Labor and Birth

    Article • American Journal of Reproductive Immunology, December 2015, Wiley

    Nardhy Gomez-Lopez

  58. Vaginal progesterone, but not 17α-hydroxyprogesterone caproate, has antiinflammatory effects at the murine maternal-fetal interface

    Article • American Journal of Obstetrics and Gynecology, December 2015, Elsevier

    Nardhy Gomez-Lopez

  59. Interleukin-6 controls uterine Th9 cells and CD8+ T regulatory cells to accelerate parturition in mice

    Article • Immunology and Cell Biology, June 2015, Nature

    Nardhy Gomez-Lopez

  60. Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface

    Article • Journal of Visualized Experiments, May 2015, MyJove Corporation

    Nardhy Gomez-Lopez

  61. Isolation of Leukocytes from the Human Maternal-fetal Interface

    Article • Journal of Visualized Experiments, May 2015, MyJove Corporation

    Nardhy Gomez-Lopez

  62. An imbalance between innate and adaptive immune cells at the maternal–fetal interface occurs prior to endotoxin-induced preterm birth

    Article • Cellular and Molecular Immunology, April 2015, Nature

    Nardhy Gomez-Lopez

  63. Transcriptomics of Maternal and Fetal Membranes Can Discriminate between Gestational-Age Matched Preterm Neonates with and without Cognitive Impairment Diagnosed at 18–24 Months

    Article • PLoS ONE, March 2015, PLOS

    Nardhy Gomez-Lopez

  64. Evaluation of reference genes for expression studies in leukocytes from term human pregnancy

    Article • Placenta, February 2015, Elsevier

    Nardhy Gomez-Lopez

  65. Chemotactic Activity of Gestational Tissues Through Late Pregnancy, Term Labor, and RU486-Induced Preterm Labor in Guinea Pigs

    Article • American Journal of Reproductive Immunology, October 2014, Wiley

    Nardhy Gomez-Lopez

  66. Immune cells in term and preterm labor

    Article • Cellular and Molecular Immunology, June 2014, Nature

    Nardhy Gomez-Lopez

  67. 737: Activation of the fetal but not maternal adaptive immune system in preterm premature rupture of membranes (PPROM)

    Article • American Journal of Obstetrics and Gynecology, January 2014, Elsevier

    Nardhy Gomez-Lopez

  68. Choriodecidual Cells From Term Human Pregnancies Show Distinctive Functional Properties Related to the Induction of Labor

    Article • American Journal of Reproductive Immunology, November 2013, Wiley

    Nardhy Gomez-Lopez

  69. The apoptotic pathway in fertile and subfertile men: a case-control and prospective study to examine the impact of merocyanine 540 bodies on ejaculated spermatozoa

    Article • Fertility and Sterility, April 2013, Elsevier

    Nardhy Gomez-Lopez

  70. Evidence for a Role for the Adaptive Immune Response in Human Term Parturition

    Article • American Journal of Reproductive Immunology, January 2013, Wiley

    Nardhy Gomez-Lopez

  71. Maternal circulating leukocytes display early chemotactic responsiveness during late gestation

    Article • BMC Pregnancy and Childbirth, January 2013, Springer Science + Business Media

    Nardhy Gomez-Lopez

  72. Working memory performance in young adults is associated to the AATn polymorphism of the CNR1 gene

    Article • Behavioural Brain Research, January 2013, Elsevier

    Nardhy Gomez-Lopez

  73. Faculty of 1000 evaluation for Pregnancy imprints regulatory memory that sustains anergy to fetal antigen.

    Article • November 2012, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  74. T regulatory cells: regulating both term and preterm labor?

    Article • Immunology and Cell Biology, October 2012, Nature

    Nardhy Gomez-Lopez

  75. Faculty of 1000 evaluation for Chemokine gene silencing in decidual stromal cells limits T cell access to the maternal-fetal interface.

    Article • September 2012, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  76. Interleukin-6 in pregnancy and gestational disorders

    Article • Journal of Reproductive Immunology, September 2012, Elsevier

    Nardhy Gomez-Lopez

  77. The Pathophysiology of Preeclampsia Involves Altered Levels of Angiogenic Factors Promoted by Hypoxia and Autoantibody-Mediated Mechanisms1

    Article • Biology of Reproduction, August 2012, Oxford University Press (OUP)

    Nardhy Gomez-Lopez

  78. Normal and Premature Rupture of Fetal Membranes at Term Delivery Differ in Regional Chemotactic Activity and Related Chemokine/Cytokine Production

    Article • Reproductive Sciences, July 2012, SAGE Publications

    Nardhy Gomez-Lopez

  79. Combined Boyden-Flow Cytometry Assay Improves Quantification and Provides Phenotypification of Leukocyte Chemotaxis

    Article • PLoS ONE, December 2011, PLOS

    Nardhy Gomez-Lopez

  80. Specific inflammatory microenvironments in the zones of the fetal membranes at term delivery

    Article • American Journal of Obstetrics and Gynecology, September 2011, Elsevier

    Nardhy Gomez-Lopez

  81. Re: The Effect of Paternal Age on Assisted Reproduction Outcome

    Article • The Journal of Urology, September 2011, Elsevier

    Nardhy Gomez-Lopez

  82. Faculty of 1000 evaluation for Progesterone increases systemic and local uterine proportions of CD4+CD25+ Treg cells during midterm pregnancy in mice.

    Article • August 2011, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  83. Involvement of the AATn polymorphism of the CNR1 gene in the efficiency of procedural learning in humans

    Article • Neuroscience Letters, May 2011, Elsevier

    Nardhy Gomez-Lopez

  84. Choriodecidua and amnion exhibit selective leukocyte chemotaxis during term human labor

    Article • American Journal of Obstetrics and Gynecology, April 2011, Elsevier

    Nardhy Gomez-Lopez

  85. Faculty of 1000 evaluation for GM-CSF is an essential regulator of T cell activation competence in uterine dendritic cells during early pregnancy in mice.

    Article • February 2011, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  86. An immunological insight into the origins of pre-eclampsia

    Article • Human Reproduction Update, December 2010, Oxford University Press (OUP)

    Nardhy Gomez-Lopez

  87. The effect of age on the expression of apoptosis biomarkers in human spermatozoa

    Article • Fertility and Sterility, December 2010, Elsevier

    Nardhy Gomez-Lopez

  88. Faculty of 1000 evaluation for Temporal changes in myeloid cells in the cervix during pregnancy and parturition.

    Article • November 2010, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  89. Interaction between Pathogenic Bacteria and Intrauterine Leukocytes Triggers Alternative Molecular Signaling Cascades Leading to Labor in Women

    Article • Infection and Immunity, August 2010, ASM Journals

    Nardhy Gomez-Lopez

  90. Faculty of 1000 evaluation for Characterization of the transcriptome of chorioamniotic membranes at the site of rupture in spontaneous labor at term.

    Article • June 2010, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  91. Invasion of the leukocytes into the fetal-maternal interface during pregnancy

    Article • Journal of Leukocyte Biology, June 2010, Society for Leukocyte Biology

    Nardhy Gomez-Lopez

  92. The Role of Chemokines in Term and Premature Rupture of the Fetal Membranes: A Review1

    Article • Biology of Reproduction, May 2010, Oxford University Press (OUP)

    Nardhy Gomez-Lopez

  93. An immunological insight into the origins of pre-eclampsia

    Article • Human Reproduction Update, April 2010, Oxford University Press (OUP)

    Nardhy Gomez-Lopez

  94. Faculty of 1000 evaluation for Pro-inflammatory and anti-inflammatory cytokines in human preterm and term cervical ripening.

    Article • March 2010, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  95. Faculty of 1000 evaluation for A role for IL-17 in induction of an inflammation at the fetomaternal interface in preterm labour.

    Article • February 2010, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  96. Placental blood leukocytes are functional and phenotypically different than peripheral leukocytes during human labor

    Article • Journal of Reproductive Immunology, January 2010, Elsevier

    Nardhy Gomez-Lopez

  97. Faculty of 1000 evaluation for Prevention of inflammatory activation of human gestational membranes in an ex vivo model using a pharmacological NF-kappaB inhibitor.

    Article • December 2009, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  98. Faculty of 1000 evaluation for Fetal-maternal HLA-C mismatch is associated with decidual T cell activation and induction of functional T regulatory cells.

    Article • December 2009, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  99. Faculty of 1000 evaluation for Leukocytes are primed in peripheral blood for activation during term and preterm labour.

    Article • October 2009, Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  100. Fetal membranes exhibit selective leukocyte chemotaxic activity during human labor

    Article • Journal of Reproductive Immunology, June 2009, Elsevier

    Nardhy Gomez-Lopez

  101. Faculty of 1000 evaluation for A distinct subset of HLA-DR+-regulatory T cells is involved in the induction of preterm labor during pregnancy and in the induction of organ rejection after transplantation.

    Article • Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  102. Faculty of 1000 evaluation for Seminal fluid regulates accumulation of FOXP3+ regulatory T Cells in the preimplantation mouse uterus through expanding the FOXP3+ cell pool and CCL19-mediated recruitment.

    Article • Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez

  103. Faculty of 1000 evaluation for Systemic increase in the ratio between Foxp3+ and IL-17-producing CD4+ T cells in healthy pregnancy but not in preeclampsia.

    Article • Faculty of 1000, Ltd.

    Nardhy Gomez-Lopez