All Stories

  1. Synthesis, antifungal evaluation and in silico study of novel Schiff bases derived from 4-amino-5(3,5-dimethoxy-phenyl)-4H-1,2,4-triazol-3-thiol

    Article • Arabian Journal of Chemistry, May 2017, Elsevier

    Dr N.S. Hari Narayana moorthy

  2. A new simple and rapid validated RP-HPLC method for determination of ziprasidone in ziprasidone capsules

    Article • Journal of Saudi Chemical Society, September 2016, Elsevier

    Dr N.S. Hari Narayana moorthy, Chandrabose Karthikeyan

  3. Fused Aryl-Phenazines: Scaffold for the Development of Bioactive Molecules

    Article • Current Drug Targets, June 2014, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  4. Binding mode prediction and identification of new lead compounds from natural products as renin and angiotensin converting enzyme inhibitors

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Dr N.S. Hari Narayana moorthy

  5. Analysis of surface area features of structurally diverse molecules for Bcr/Abl kinase inhibitory activity and antiproliferative activity

    Article • Medicinal Chemistry Research, October 2013, Springer Science + Business Media

    Dr N.S. Hari Narayana moorthy

  6. Development of Ribonucleotide Reductase Inhibitors: A Review on Structure Activity Relationships

    Article • Mini-Reviews in Medicinal Chemistry, October 2013, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  7. Synthesis and evaluation of some amino acid conjugates of pirprofen

    Article • Biomedicine & Preventive Nutrition, July 2013, Elsevier

    Dr N.S. Hari Narayana moorthy

  8. Synthesis and evaluation of some amino acid conjugates of suprofen

    Article • Biomedicine & Preventive Nutrition, July 2013, Elsevier

    Dr N.S. Hari Narayana moorthy

  9. 6H-Indolo[2,3-b]Quinoxalines: DNA and Protein Interacting Scaffold for Pharmacological Activities

    Article • Mini-Reviews in Medicinal Chemistry, July 2013, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  10. Atom based 3D-QSAR study of 1,4-benzodiazepine-2-ones as potent anti-trypanosomal agents and its validation

    Article • Medicinal Chemistry Research, June 2013, Springer Science + Business Media

    Dr N.S. Hari Narayana moorthy

  11. Aryl- and Heteroaryl-Thiosemicarbazone Derivatives and Their Metal Complexes: A Pharmacological Template

    Article • Recent Patents on Anti-Cancer Drug Discovery, May 2013, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  12. Predictive QSAR models development and validation for human ether-a-go-go related gene (hERG) blockers using newer tools

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, April 2013, Taylor & Francis

    Dr N.S. Hari Narayana moorthy

  13. QSAR and Pharmacophore Analysis of a Series of Piperidinyl Urea Derivatives as hERG Blockers and H3 Antagonists

    Article • Current Drug Discovery Technologies, March 2013, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  14. Design, synthesis and biological evaluation of novel arylidine-malononitrile derivatives as non-carboxylic inhibitors of protein tyrosine phosphatase 1B

    Article • Medicinal Chemistry Research, February 2013, Springer Science + Business Media

    Dr N.S. Hari Narayana moorthy, Chandrabose Karthikeyan

  15. Aryl- and Heteroaryl-Thiosemicarbazone Derivatives and Their Metal Complexes: A Pharmacological Template

    Article • Recent Patents on Anti-Cancer Drug Discovery, February 2013, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  16. QSAR and Pharmacophore Analysis of a Series of Piperidinyl Urea Derivatives as hERG Blockers and H3 Antagonists

    Article • Current Drug Discovery Technologies, January 2013, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  17. Combined ligand and structure based binding mode analysis of oxidosqualene cyclase inhibitors

    Article • RSC Advances, January 2013, Royal Society of Chemistry

    Dr N.S. Hari Narayana moorthy, Professor Pedro Alexandrino Fernandes

  18. Human Ether-a-Go-Go-Related Gene Channel Blockers and its Structural Analysis for Drug Design

    Article • Current Drug Targets, January 2013, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  19. Human Ether-a-Go-Go-Related Gene Channel Blockers and its Structural Analysis for Drug Design

    Article • Current Drug Targets, December 2012, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  20. In silico Based Structural Analysis of Some Piperidine Analogs as Farnesyltransferase Inhibitors

    Article • Medicinal Chemistry, September 2012, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  21. Synthesis, Characterization, Biological Evaluation and Docking of Coumarin Coupled Thiazolidinedione Derivatives and its Bioisosteres as PPARγ Agonists

    Article • Medicinal Chemistry, September 2012, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  22. Structural Analysis of 2-Piperidin-4-yl-Actamide Derivatives for hERG Blocking and MCH R1 Antagonistic Activities

    Article • Current Drug Discovery Technologies, March 2012, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  23. Modeling VEGFR kinase inhibition of aminopyrazolopyridine urea derivatives using topological and physicochemical descriptors: a quantitative structure activity analysis study

    Article • Medicinal Chemistry Research, December 2011, Springer Science + Business Media

    Dr N.S. Hari Narayana moorthy, Chandrabose Karthikeyan

  24. Structural analysis of α-glucosidase inhibitors by validated QSAR models using topological and hydrophobicity based descriptors

    Article • Chemometrics and Intelligent Laboratory Systems, December 2011, Elsevier

    Dr N.S. Hari Narayana moorthy

  25. Analysis of the α-Glucosidase Inhibitory Activity of Chromenone Derivatives Based on their Molecular Features: A Computational Study

    Article • Medicinal Chemistry, November 2011, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  26. Comparative Structural Analysis of α‐Glucosidase Inhibitors on Difference Species: A Computational Study

    Article • Archiv der Pharmazie, October 2011, Wiley

    Dr N.S. Hari Narayana moorthy

  27. COMPARATIVE STUDY OF FORCED DEGRADATION BEHAVIOR OF PRASUGREL BY UPLC AND HPLC AND THE DEVELOPMENT OF VALIDATED STABILITY INDICATING ASSAY METHOD

    Article • Journal of Liquid Chromatography &amp Related Technologies, October 2011, Taylor & Francis

    Dr N.S. Hari Narayana moorthy

  28. In Silico–Based Structural Analysis of Arylthiophene Derivatives for FTase Inhibitory Activity, hERG, and Other Toxic Effects

    Article • SLAS DISCOVERY, October 2011, Elsevier

    Dr N.S. Hari Narayana moorthy

  29. Structural analysis of structurally diverse α-glucosidase inhibitors for active site feature analysis

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, September 2011, Taylor & Francis

    Dr N.S. Hari Narayana moorthy

  30. A Validated UPLC Method Used for the Determination of Trandolapril and its Degradation Products as per ICH Guidelines

    Article • Current Pharmaceutical Analysis, August 2011, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy, Chandrabose Karthikeyan

  31. Design, synthesis and biological evaluation of some novel 3-cinnamoyl-4-hydroxy-2H-chromen-2-ones as antimalarial agents

    Article • Medicinal Chemistry Research, June 2011, Springer Science + Business Media

    Dr N.S. Hari Narayana moorthy, Chandrabose Karthikeyan, Viswas Raja Solomon

  32. Synthesis, in silico metabolic and toxicity prediction of some novel imidazolinones derivatives as potent anticonvulsant agents

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, June 2011, Taylor & Francis

    Dr N.S. Hari Narayana moorthy

  33. Synthesis of Some Coumarinyl Chalcones and their Antiproliferative Activity Against Breast Cancer Cell Lines

    Article • Letters in Drug Design & Discovery, May 2011, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy, Chandrabose Karthikeyan, Viswas Raja Solomon

  34. Structural feature study of benzofuran derivatives as farnesyltransferase inhibitors

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, March 2011, Taylor & Francis

    Dr N.S. Hari Narayana moorthy

  35. QSAR and pharmacophore analysis of thiosemicarbazone derivatives as ribonucleotide reductase inhibitors

    Article • Medicinal Chemistry Research, February 2011, Springer Science + Business Media

    Dr N.S. Hari Narayana moorthy

  36. Topological, hydrophobicity, and other descriptors on α-glucosidase inhibition: a QSAR study on xanthone derivatives

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, February 2011, Taylor & Francis

    Dr N.S. Hari Narayana moorthy

  37. hERG binding feature analysis of structurally diverse compounds by QSAR and fragmental analysis

    Article • RSC Advances, January 2011, Royal Society of Chemistry

    Dr N.S. Hari Narayana moorthy

  38. QSAR Analysis of Isosteviol Derivatives as α-Glucosidase Inhibitors with Element Count and Other Descriptors

    Article • Letters in Drug Design & Discovery, January 2011, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  39. Prediction of the relationship between the structural features of andrographolide derivatives and α-glucosidase inhibitory activity: A quantitative structure-activity relationship (QSAR) Study

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, December 2010, Taylor & Francis

    Dr N.S. Hari Narayana moorthy

  40. QSAR analysis of 2-benzoxazolyl hydrazone derivatives for anticancer activity and its possible target prediction

    Article • Medicinal Chemistry Research, December 2010, Springer Science + Business Media

    Dr N.S. Hari Narayana moorthy

  41. 3D QSAR of Aminophenyl Benzamide Derivatives as Histone Deacetylase Inhibitors

    Article • Medicinal Chemistry, September 2010, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  42. A new approach for PEGylation of dendrimers

    Article • Bioorganic & Medicinal Chemistry Letters, July 2010, Elsevier

    Dr N.S. Hari Narayana moorthy

  43. Design, synthesis, cytotoxic evaluation, and QSAR study of some 6H-indolo[2,3-b]quinoxaline derivatives

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, March 2010, Taylor & Francis

    Dr N.S. Hari Narayana moorthy

  44. Synthesis, Cytotoxic Evaluation and In Silico Pharmacokinetic Prediction of Some Benzo[a]Phenazine-5-sulfonic acid Derivatives

    Article • Medicinal Chemistry, November 2009, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  45. QSAR study on N- (Aryl)-4-(Azolylethyl) Thiazole-5-Carboxamides: Novel Potent Inhibitors of VEGF Receptors I and II

    Article • Medicinal Chemistry, September 2009, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  46. QSAR study of substituted 2-pyridinyl guanidines as selective urokinase-type plasminogen activator (uPA) inhibitors

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, February 2009, Taylor & Francis

    Dr N.S. Hari Narayana moorthy

  47. Quantitative Structure Activity Analysis of 2-Alkoxydihydrocinnamates as PPARα /γ Dual Agonist

    Article • Medicinal Chemistry, May 2008, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  48. Synthesis and Anti-microbial Evaluation of Some 3, 4-Dihydro Pyrimidine-2-one Derivatives

    Article • Trends in Applied Sciences Research, February 2008, Science Alert

    Dr N.S. Hari Narayana moorthy

  49. Quantitative Structure Activity Relationship Analysis of Some Diarylsulphonylurea Derivatives as Tubulin Binding Agents

    Article • International Journal of Cancer Research, January 2008, Science Alert

    Dr N.S. Hari Narayana moorthy

  50. Synthesis, Biological Evaluation and in silico Metabolic and Toxicity Prediction of Some Flavanone Derivatives.

    Article • ChemInform, March 2007, Wiley

    Dr N.S. Hari Narayana moorthy

  51. QSAR Studies of 6‐Amino Uracil Base Analogues: A Thymidine Phosphorylase Inhibitor in Cancer Therapy

    Article • Journal of Chemistry, February 2007, Wiley

    Dr N.S. Hari Narayana moorthy

  52. Synthesis and Physicochemical Characterization of Mutual Prodrug of Indomethacin

    Article • Trends in Applied Sciences Research, February 2007, Science Alert

    Dr N.S. Hari Narayana moorthy

  53. Synthesis and Characterization of Some Chalcone Derivatives

    Article • Trends in Applied Sciences Research, January 2007, Science Alert

    Dr N.S. Hari Narayana moorthy

  54. Insulin like Growth Factor-1 Receptor: An Anticancer Target Waiting for Hit

    Article • International Journal of Cancer Research, January 2007, Science Alert

    Dr N.S. Hari Narayana moorthy

  55. Comparative Studies on Conventional and Microwave Assisted Synthesis of Benzimidazole and Their 2-Substituted Derivative with the Effect of Salt Form of Reactant

    Article • Chemical and Pharmaceutical Bulletin, January 2007, Pharmaceutical Society of Japan

    Dr N.S. Hari Narayana moorthy

  56. QSAR Analysis of HIV-1 Reverse Transcriptase Inhibitory 5-Alkyl-2- [(Aryl and Alkyloxylcarbonylmethyl) Thio]-6- (1-Napthylmethyl) Pyrimidin-4 (3H)-Ones

    Article • International Journal of Virology, January 2007, Science Alert

    Dr N.S. Hari Narayana moorthy

  57. QSAR analysis of some 5-amino-2-mercapto-1,3,4-thiadiazole based inhibitors of matrix metalloproteinases and bacterial collagenase

    Article • Bioorganic & Medicinal Chemistry Letters, July 2006, Elsevier

    Dr N.S. Hari Narayana moorthy

  58. 2-(4-Aminophenyl) Benzothiazole: A Potent and Selective Pharmacophore with Novel Mechanistic Action Towards Various Tumour Cell Lines

    Article • Mini-Reviews in Medicinal Chemistry, June 2006, Bentham Science Publishers

    Dr N.S. Hari Narayana moorthy

  59. Quantitative Structure Activity Relationships of Some Selective Inhibitors of Glucagon Receptor: A Hansch Approach

    Article • Asian Journal of Biochemistry, April 2006, Science Alert

    Dr N.S. Hari Narayana moorthy

  60. QSAR Studies on Some GSK-3a Inhibitory 6-aryl-pyrazolo (3,4-b) pyridines

    Article • Asian Journal of Biochemistry, March 2006, Science Alert

    Dr N.S. Hari Narayana moorthy

  61. Synthesis, Biological Evaluation and In Silico Metabolic and Toxicity Prediction of Some Flavanone Derivatives

    Article • Chemical and Pharmaceutical Bulletin, January 2006, Pharmaceutical Society of Japan

    Dr N.S. Hari Narayana moorthy

  62. Quantitative Structure–Activity Relationships of Selective Antagonists of Glucagon Receptor Using QuaSAR Descriptors

    Article • Chemical and Pharmaceutical Bulletin, January 2006, Pharmaceutical Society of Japan

    Dr N.S. Hari Narayana moorthy, Chandrabose Karthikeyan

  63. Dihydrofolate Reductase Enzyme: A Potent Target for Antimalarial Research

    Article • Asian Journal of Cell Biology, January 2006, Science Alert

    Dr N.S. Hari Narayana moorthy

  64. QSAR modelling of HIV-1 reverse transcriptase inhibition by benzoxazinones using a combination of P_VSA and pharmacophore feature descriptors

    Article • Bioorganic & Medicinal Chemistry Letters, December 2004, Elsevier

    Dr N.S. Hari Narayana moorthy