All Stories

  1. Oral lactate slows gastric emptying and suppresses appetite in young males
  2. Dicarbonyl derived post-translational modifications: chemistry bridging biology and aging-related disease
  3. Methylglyoxal Metabolism and Aging-Related Disease: Moving from Correlation toward Causation
  4. Non-enzymatic Lysine Lactoylation of Glycolytic Enzymes
  5. ReactELISA method for quantifying methylglyoxal levels in plasma and cell cultures
  6. STEFs: Activated Vinylogous Protein-Reactive Electrophiles
  7. Sensitive determination of monoamine neurotransmitters, their main metabolites and precursor amino acids in different mouse brain components by liquid chromatography-electrospray tandem mass spectrometry after selective sample clean-up
  8. Profiling of Methylglyoxal Blood Metabolism and Advanced Glycation End-Product Proteome Using a Chemical Probe
  9. Substrate metabolism, hormone and cytokine levels and adipose tissue signalling in individuals with type 1 diabetes after insulin withdrawal and subsequent insulin therapy to model the initiating steps of ketoacidosis
  10. Effects of 3-hydroxybutyrate and free fatty acids on muscle protein kinetics and signaling during LPS-induced inflammation in humans: anticatabolic impact of ketone bodies
  11. APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells
  12. cGAS is activated by DNA in a length‐dependent manner
  13. Ketone Body Acetoacetate Buffers Methylglyoxal via a Non-enzymatic Conversion during Diabetic and Dietary Ketosis
  14. ReactELISA: Monitoring a Carbon Nucleophilic Metabolite by ELISA—a Study of Lipid Metabolism
  15. Untargeted metabolomics reveals a mild impact of remote ischemic conditioning on the plasma metabolome and α-hydroxybutyrate as a possible cardioprotective factor and biomarker of tissue ischemia
  16. IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP
  17. Untargeted Metabolomics Analysis of ABCC6-Deficient Mice Discloses an Altered Metabolic Liver Profile
  18. Citric Acid Cycle Metabolites Predict the Severity of Myocardial Stunning and Mortality in Newborn Pigs
  19. Synthesis of ent-BE-43547A1 reveals a potent hypoxia-selective anticancer agent and uncovers the biosynthetic origin of the APD-CLD natural products
  20. Effects of insulin-induced hypoglycaemia on lipolysis rate, lipid oxidation and adipose tissue signalling in human volunteers: a randomised clinical study
  21. Reply: Letter to the editor – A dietary amino acid load causes a transient decrease in the function of human neutrophil granulocytes
  22. Untargeted Metabolomics Analysis Reveals a Link between ETHE1-Mediated Disruptive Redox State and Altered Metabolic Regulation
  23. Anabolic effects of leucine-rich whey protein, carbohydrate, and soy protein with and without β-hydroxy-β-methylbutyrate (HMB) during fasting-induced catabolism: A human randomized crossover trial
  24. Amino acid supplementation is anabolic during the acute phase of endotoxin-induced inflammation: A human randomized crossover trial
  25. Combined Insulin Deficiency and Endotoxin Exposure Stimulate Lipid Mobilization and Alter Adipose Tissue Signaling in an Experimental Model of Ketoacidosis in Subjects With Type 1 Diabetes: A Randomized Controlled Crossover Trial
  26. A Metabolomics Study of Retrospective Forensic Data from Whole Blood Samples of Humans Exposed to 3,4-Methylenedioxymethamphetamine: A New Approach for Identifying Drug Metabolites and Changes in Metabolism Related to Drug Consumption
  27. In vivo drug release behavior and osseointegration of a doxorubicin-loaded tissue-engineered scaffold
  28. The natural product brartemicin is a high affinity ligand for the carbohydrate-recognition domain of the macrophage receptor mincle
  29. A cleavable azide resin for direct click chemistry mediated enrichment of alkyne-labeled proteins
  30. Remote ischemic preconditioning with – but not without – metabolic support protects the neonatal porcine heart against ischemia-reperfusion injury
  31. Simultaneous determination of β-hydroxybutyrate and β-hydroxy-β-methylbutyrate in human whole blood using hydrophilic interaction liquid chromatography electrospray tandem mass spectrometry
  32. Protection against Myocardial Ischemia-Reperfusion Injury at Onset of Type 2 Diabetes in Zucker Diabetic Fatty Rats Is Associated with Altered Glucose Oxidation
  33. Development of a chemical probe for identifying protein targets of α-oxoaldehydes
  34. Screening analysis for medicinal drugs and drugs of abuse in whole blood using ultra-performance liquid chromatography time-of-flight mass spectrometry (UPLC–TOF-MS)—Toxicological findings in cases of alleged sexual assault
  35. Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway
  36. A UPLC–MS/MS application for profiling of intermediary energy metabolites in microdialysis samples—A method for high-throughput
  37. Inhibition of the malate–aspartate shuttle by pre-ischaemic aminooxyacetate loading of the heart induces cardioprotection
  38. ChemInform Abstract: Catalytic Enantioselective Aza Diels-Alder Reactions of Imino Dienophiles.
  39. ChemInform Abstract: A Highly Enantioselective Hetero-Diels-Alder Reaction Catalyzed by Chiral Polybinaphthyl-Aluminum Complexes.
  40. ChemInform Abstract: Catalytic Asymmetric Addition Reactions of Carbonyls. A Common Catalytic Approach
  41. ChemInform Abstract: Catalytic Approach for the Formation of Optically Active Allyl α-Amino Acids by Addition of Allylic Metal Compounds to α-Imino Esters.
  42. ChemInform Abstract: An Enantioselective Synthesis of Heteroaromatic N-Tosyl α-Amino Acids.
  43. ChemInform Abstract: Synthesis and First Application of a New Family of Monophosphine Ferrocene Ligands (MOPF).
  44. ChemInform Abstract: An Enantioselective Synthesis of Optically Pure Azaferrocenyl Anions - First General and Practical Approach to Chiral Azaferrocenes.
  45. ChemInform Abstract: A Novel Stereoselective Synthesis of N-Heterocycles by Intramolecular Hydrovinylation.
  46. ChemInform Abstract: Highly Enantioselective Hydrosilylation of Aromatic Alkenes.
  47. ChemInform Abstract: Organocatalysis with Endogenous Compounds: Towards Novel Nonenyzmatic Reactions.
  48. Organocatalysis with endogenous compounds: Towards novel non-enzymatic reactions
  49. A fatal poisoning involving Bromo-Dragonfly
  50. Synthesis and Application of Aryl-Ferrocenyl (Pseudo-Biarylic) Complexes. Part 5. Design and Synthesis of a New Type of Ferrocene-Based Planar Chiral DMAP Analogues. A New Catalyst System for Asymmetric Nucleophilic Catalysis.
  51. Design and Synthesis of a New Type of Ferrocene-Based Planar Chiral DMAP Analogues. A New Catalyst System for Asymmetric Nucleophilic Catalysis.
  52. Design and Synthesis of a New Type of Ferrocene-Based Planar Chiral DMAP Analogues. A New Catalyst System for Asymmetric Nucleophilic Catalysis
  53. Synthesis and Application of Aryl-Ferrocenyl (Pseudo-Biarylic) Complexes. Part 4. New Air-Stable Planar Chiral Ferrocenyl Monophosphine Ligands: Suzuki Cross-Coupling of Aryl Chlorides and Bromides.
  54. New Air-Stable Planar Chiral Ferrocenyl Monophosphine Ligands:  Suzuki Cross-Coupling of Aryl Chlorides and Bromides
  55. Synthesis and Application of Arylmonophosphinoferrocene Ligands: Ultrafast Asymmetric Hydrosilylation of Styrene.
  56. Pentamethylated and Pentaphenylated Azaferro- and Azaruthenocenes:  Simple and General Methodology for the Preparation of Enantiopure Derivatives
  57. Modular Approach to Novel Chiral Aryl-Ferrocenyl Phosphines by Suzuki Cross-Coupling
  58. Synthesis and Application of Arylmonophosphinoferrocene Ligands:  Ultrafast Asymmetric Hydrosilylation of Styrene
  59. Highly Enantioselective Hydrosilylation of Aromatic Alkenes
  60. A novel stereoselective synthesis of N-heterocycles by intramolecular hydrovinylationElectronic supplementary information (ESI) available: 1H and 13C NMR spectra of compounds 1a–f, 2a–d, 3–5, 8–10. See http://www.rsc.org/suppdata/p1/b1/b108310d/
  61. An Enantioselective Synthesis of Optically Pure Azaferrocenyl AnionsFirst General and Practical Approach to Chiral Azaferrocenes
  62. Catalytic Approach for the Formation of Optically Active Allyl α-Amino Acids by Addition of Allylic Metal Compounds to α-Imino Esters
  63. Catalytic Asymmetric Addition Reactions of Carbonyls. A Common Catalytic Approach
  64. An enantioselective synthesis of heteroaromatic N-tosyl α-amino acids
  65. Synthesis and first application of a new family of monophosphine ferrocene ligands (MOPF)
  66. A Highly Enantioselective Hetero-Diels−Alder Reaction Catalyzed by Chiral Polybinaphthyl−Aluminum Complexes
  67. Catalytic Enantioselective Aza Diels-Alder Reactions of Imino Dienophiles
  68. Katalytische enantioselektive Aza-Diels-Alder-Reaktionen von Imino-Dienophilen
  69. Katalytische enantioselektive Aza-Diels-Alder-Reaktionen von Imino-Dienophilen
  70. Highly Enantioselective Catalytic Hetero-Diels-Alder Reaction with Inverse Electron Demand
  71. Hochenantioselektive katalytische Hetero-Diels-Alder-Reaktion mit inversem Elektronenbedarf
  72. Catalytic Asymmetric Hetero-Diels−Alder Reactions of Ketones:  Chemzymatic Reactions
  73. Synthesis and Application of the First Chiral and Highly Lewis Acidic Silyl Cationic Catalyst
  74. Allylic Amination
  75. Metal-catalyzed asymmetric hetero-DielsAlder reactions of unactivated dienes with glyoxylates
  76. Total Synthesis of (R)-Dihydroactinidiolide and (R)-Actinidiolide Using Asymmetric Catalytic Hetero-Diels−Alder Methodology
  77. The first highly enantioselective catalytic hetero-Diels–Alder reaction of ketones
  78. Zinc(II)-catalysed asymmetric hetero-Diels–Alder reactions of conjugated dienes with glyoxylate
  79. Solvent vs. counterion acceleration of enantioselective carbo and hetero Diels–Alder reactions
  80. Solvent effects in asymmetric hetero Diels-Alder and ene reactions
  81. A highly chemo- and enantio-selective hetero-Diels–Alder reaction catalysed by chiral aluminium complexes
  82. Mechanistic aspects of iron-catalyzed allylic amination
  83. Asymmetric hetero Diels-Alder reactions and ene reactions catalyzed by chiral copper(II) complexes
  84. Iron-catalyzed allylic amination