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  1. Neutron diffraction from a microgravity-grown crystal reveals the active site hydrogens of the internal aldimine form of tryptophan synthase

    Article • Cell Reports Physical Science, February 2024, Elsevier

    Dr Matthew P Blakeley

  2. Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography

    Article • Communications Chemistry, August 2023, Springer Science + Business Media

    Dr Matthew P Blakeley

  3. Perdeuterated GbpA Enables Neutron Scattering Experiments of a Lytic Polysaccharide Monooxygenase

    Article • ACS Omega, July 2023, American Chemical Society (ACS)

    Dr Matthew P Blakeley

  4. Microgravity crystallization and neutron diffraction of perdeuterated tryptophan synthase

    Article • Acta Crystallographica Section A Foundations and Advances, July 2022, International Union of Crystallography

    Dr Matthew P Blakeley

  5. Microgravity crystallization of perdeuterated tryptophan synthase for neutron diffraction

    Article • npj Microgravity, May 2022, Springer Science + Business Media

    Dr Matthew P Blakeley

  6. Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease

    Article • Nature Communications, April 2022, Springer Science + Business Media

    Dr Matthew P Blakeley

  7. Neutron crystallography reveals mechanisms used by Pseudomonas aeruginosa for host-cell binding

    Article • Nature Communications, January 2022, Springer Science + Business Media

    Dr Matthew P Blakeley

  8. An N⋯H⋯N low-barrier hydrogen bond preorganizes the catalytic site of aspartate aminotransferase to facilitate the second half-reaction

    Article • Chemical Science, January 2022, Royal Society of Chemistry

    Dr Matthew P Blakeley

  9. Human myelin protein P2: From crystallography to time‐lapse membrane imaging and neuropathy‐associated variants

    Article • European Journal of Biochemistry, June 2021, Wiley

    Dr Matthew P Blakeley

  10. Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps

    Article • IUCrJ, June 2021, International Union of Crystallography

    Dr Matthew P Blakeley, rik wierenga

  11. Visualization of hydrogen atoms in a perdeuterated lectin-fucose complex reveals key details of protein-carbohydrate interactions

    Article • Structure, March 2021, Elsevier

    Dr Matthew P Blakeley

  12. Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis

    Article • IUCrJ, January 2021, International Union of Crystallography

    Roberto Steiner, Dr Matthew P Blakeley

  13. Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure

    Article • Current Research in Structural Biology, January 2021, Elsevier

    Dr Matthew P Blakeley

  14. Production of perdeuterated fucose from glyco-engineered bacteria

    Article • Glycobiology, June 2020, Oxford University Press (OUP)

    Dr Matthew P Blakeley

  15. Visualizing Tetrahedral Oxyanion Bound in HIV-1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design

    Article • ACS Omega, May 2020, American Chemical Society (ACS)

    Dr Matthew P Blakeley

  16. Visualizing the protons in a metalloenzyme electron proton transfer pathway

    Article • Proceedings of the National Academy of Sciences, March 2020, Proceedings of the National Academy of Sciences

    Dr Matthew P Blakeley

  17. Protein kinase A in the neutron beam: Insights for catalysis from directly observing protons

    Article • January 2020, Elsevier

    Dr Matthew P Blakeley

  18. Proton transfer and drug binding details revealed in neutron diffraction studies of wild-type and drug resistant HIV-1 protease

    Article • January 2020, Elsevier

    Dr Matthew P Blakeley

  19. Heme peroxidase—Trapping intermediates by cryo neutron crystallography

    Article • January 2020, Elsevier

    Dr Matthew P Blakeley

  20. Catalytically important damage-free structures of a copper nitrite reductase obtained by femtosecond X-ray laser and room-temperature neutron crystallography

    Article • IUCrJ, June 2019, International Union of Crystallography

    Professor Samar Hasnain, Dr Matthew P Blakeley

  21. Perdeuteration, large crystal growth and neutron data collection ofLeishmania mexicanatriose-phosphate isomerase E65Q variant

    Article • Acta Crystallographica Section F Structural Biology Communications, April 2019, International Union of Crystallography

    Dr Matthew P Blakeley

  22. Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex

    Article • Science Advances, March 2019, American Association for the Advancement of Science

    Dr Matthew P Blakeley

  23. A molecular mechanism for transthyretin amyloidogenesis

    Article • Nature Communications, February 2019, Springer Science + Business Media

    Dr Matthew P Blakeley, Dr Matthew W Bowler

  24. Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative

    Article • Journal of Structural Biology, February 2019, Elsevier

    Dr Matthew P Blakeley

  25. Temperature-Induced Replacement of Phosphate Proton with Metal Ion Captured in Neutron Structures of A-DNA

    Article • Structure, September 2018, Elsevier

    Dr Matthew P Blakeley

  26. Joint X-ray and neutron protein crystallography for the study of enzyme-isoform selectivity by small-molecule inhibitors

    Article • Acta Crystallographica Section A Foundations and Advances, August 2018, International Union of Crystallography

    Dr Matthew P Blakeley

  27. The missing atom in function: reliability of the determination of hydrogen positions in protein structures.

    Article • Acta Crystallographica Section A Foundations and Advances, July 2018, International Union of Crystallography

    Dr Matthew P Blakeley

  28. Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design

    Article • Journal of Medicinal Chemistry, May 2018, American Chemical Society (ACS)

    Dr Matthew P Blakeley

  29. Neutron Crystallography Detects Differences in Protein Dynamics: Structure of the PKG II Cyclic Nucleotide Binding Domain in Complex with an Activator

    Article • Biochemistry, March 2018, American Chemical Society (ACS)

    Dr Matthew P Blakeley

  30. "To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation

    Article • Structure, March 2018, Elsevier

    Dr Matthew P Blakeley

  31. Neutron macromolecular crystallography

    Article • Emerging Topics in Life Sciences, February 2018, Portland Press Ltd.

    Dr Matthew P Blakeley

  32. Neutron crystallography of insulin using a radically small-volume crystal

    Article • Acta Crystallographica Section A Foundations and Advances, December 2017, International Union of Crystallography

    Dr Matthew P Blakeley

  33. Unravelling transthyretin amyloidosis by neutron crystallography

    Article • Acta Crystallographica Section A Foundations and Advances, December 2017, International Union of Crystallography

    Dr Matthew P Blakeley

  34. Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme

    Article • Nature Communications, October 2017, Nature

    Dr Matthew P Blakeley

  35. Direct observation of protonation states in a PLP-dependent enzyme by neutron crystallography

    Article • Acta Crystallographica Section A Foundations and Advances, May 2017, International Union of Crystallography

    Dr Matthew P Blakeley

  36. Neutron crystallographic and scattering studies of function and inhibition of HIV-1 protease

    Article • Acta Crystallographica Section A Foundations and Advances, May 2017, International Union of Crystallography

    Dr Matthew P Blakeley

  37. Back-exchange of deuterium in neutron crystallography: characterization by IR spectroscopy

    Article • Journal of Applied Crystallography, March 2017, International Union of Crystallography

    Dr Matthew P Blakeley

  38. Room Temperature Neutron Crystallography of Drug Resistant HIV-1 Protease Uncovers Limitations of X-ray Structural Analysis at 100 K

    Article • Journal of Medicinal Chemistry, February 2017, American Chemical Society (ACS)

    Dr Matthew P Blakeley

  39. An extended N-H bond, driven by a conserved second-order interaction, orients the flavin N5 orbital in cholesterol oxidase

    Article • Scientific Reports, January 2017, Nature

    Dr Matthew P Blakeley

  40. Direct visualization of a Fe(IV)–OH intermediate in a heme enzyme

    Article • Nature Communications, November 2016, Nature

    Dr Matthew P Blakeley

  41. Perdeuteration, crystallization, data collection and comparison of five neutron diffraction data sets of complexes of human galectin-3C

    Article • Acta Crystallographica Section D Structural Biology, October 2016, International Union of Crystallography

    Dr Matthew P Blakeley, Dr Derek T Logan

  42. Neutron crystallography aids in drug design

    Article • IUCrJ, August 2016, International Union of Crystallography

    Dr Matthew P Blakeley

  43. An ab initio fully deuterated tiny crystal (1x0.25x0.20mm) allows neutron data collection at room temperature up to 1.90Å

    Article • Acta Crystallographica Section A Foundations and Advances, August 2016, International Union of Crystallography

    Dr Matthew P Blakeley

  44. High resolution neutron and X-ray diffraction RT studies of an H-FABP – Oleic acid complex: study of the internal water cluster and the ligand binding by a transferred multipolar electron density distribution

    Article • Acta Crystallographica Section A Foundations and Advances, August 2016, International Union of Crystallography

    Dr Matthew P Blakeley

  45. Targeting transthyretin amyloidosis: joint neutron and X-ray diffraction analysis of a pathogenic protein

    Article • Acta Crystallographica Section A Foundations and Advances, August 2016, International Union of Crystallography

    Dr Matthew P Blakeley

  46. Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site

    Article • Angewandte Chemie, March 2016, Wiley

    Dr Matthew P Blakeley

  47. High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP–oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution

    Article • IUCrJ, January 2016, International Union of Crystallography

    Dr Matthew P Blakeley

  48. Production, crystallization and neutron diffraction of fully deuterated human myelin peripheral membrane protein P2

    Article • Acta Crystallographica Section F Structural Biology Communications, October 2015, International Union of Crystallography

    Dr Matthew P Blakeley

  49. Neutron macromolecular crystallography at the Institut Laue-Langevin

    Article • Acta Crystallographica Section A Foundations and Advances, August 2015, International Union of Crystallography

    Dr Matthew P Blakeley

  50. Sub-atomic resolution X-ray crystallography and neutron crystallography: promise, challenges and potential

    Article • IUCrJ, June 2015, International Union of Crystallography

    Dr Matthew P Blakeley, Dr Svetlana Antonyuk

  51. Perdeuteration: improved visualization of solvent structure in neutron macromolecular crystallography

    Article • Acta Crystallographica Section D Biological Crystallography, November 2014, International Union of Crystallography

    Dr Matthew P Blakeley

  52. Neutron Diffraction Reveals Hydrogen Bonds Critical for cGMP-Selective Activation: Insights for cGMP-Dependent Protein Kinase Agonist Design

    Article • Biochemistry, November 2014, American Chemical Society (ACS)

    Dr Matthew P Blakeley

  53. Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein

    Article • IUCrJ, October 2014, International Union of Crystallography

    Dr Matthew P Blakeley

  54. L-Arabinose Binding, Isomerization, and Epimerization by D-Xylose Isomerase: X-Ray/Neutron Crystallographic and Molecular Simulation Study

    Article • Structure, September 2014, Elsevier

    Dr Matthew P Blakeley

  55. Mechanism of IPPase shown by high resolution Neutron and X-ray crystallography

    Article • Acta Crystallographica Section A Foundations and Advances, August 2014, International Union of Crystallography

    Dr Matthew P Blakeley

  56. Perdeuteration: Vital to visualising solvent in neutron crystallography?

    Article • Acta Crystallographica Section A Foundations and Advances, August 2014, International Union of Crystallography

    Dr Matthew P Blakeley

  57. UHR PX and NPC studies of H-FABP water network with tiny perdeuterated crystals

    Article • Acta Crystallographica Section A Foundations and Advances, August 2014, International Union of Crystallography

    Dr Matthew P Blakeley

  58. Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase

    Article • Science, July 2014, American Association for the Advancement of Science

    Dr Matthew P Blakeley

  59. The Neutron Structure of Urate Oxidase Resolves a Long-Standing Mechanistic Conundrum and Reveals Unexpected Changes in Protonation

    Article • PLoS ONE, January 2014, PLOS

    Dr Matthew P Blakeley

  60. Joint X-ray/Neutron Crystallographic Study of HIV-1 Protease with Clinical Inhibitor Amprenavir: Insights for Drug Design

    Article • Journal of Medicinal Chemistry, July 2013, American Chemical Society (ACS)

    Dr Matthew P Blakeley

  61. Near-Atomic Resolution Neutron Crystallography on PerdeuteratedPyrococcus furiosusRubredoxin: Implication of Hydronium Ions and Protonation State Equilibria in Redox Changes

    Article • Angewandte Chemie, December 2012, Wiley

    Dr Matthew P Blakeley

  62. Inorganic pyrophosphatase crystals fromThermococcus thioreducensfor X-ray and neutron diffraction

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, November 2012, International Union of Crystallography

    Dr Matthew P Blakeley

  63. Inhibition ofD-xylose isomerase by polyols: atomic details by joint X-ray/neutron crystallography

    Article • Acta Crystallographica Section D Biological Crystallography, August 2012, International Union of Crystallography

    Dr Matthew P Blakeley

  64. A joint neutron/X-ray crystallographic study on the mechanism of pectate lyase

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2012, International Union of Crystallography

    Dr Matthew P Blakeley

  65. Determining protonation states in proteins using high-resolution X-ray crystallography

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2012, International Union of Crystallography

    Dr Matthew P Blakeley

  66. Neutron data collection at room temperature with tiny crystals of perdeuterated proteins

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2012, International Union of Crystallography

    Dr Matthew P Blakeley

  67. Neutrons on the loose: tracking down weaknesses in the hydrogen network of transthyretin

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2012, International Union of Crystallography

    Dr Matthew P Blakeley

  68. Protein neutron crystallography with 'tiny' crystals of fully deuterated proteins

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2012, International Union of Crystallography

    Dr Matthew P Blakeley

  69. Surprising protonation states in urate oxidase – combining X-ray and neutron crystallography with QM/MM

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2012, International Union of Crystallography

    Dr Matthew P Blakeley

  70. Neutron protein crystallography at ultra-low (<15 K) temperatures

    Article • Journal of Applied Crystallography, June 2012, International Union of Crystallography

    Dr Matthew P Blakeley

  71. Protonation-state determination in proteins using high-resolution X-ray crystallography: effects of resolution and completeness

    Article • Acta Crystallographica Section D Biological Crystallography, June 2012, International Union of Crystallography

    Professor John Richard Helliwell, Dr Matthew P Blakeley

  72. Rapid visualization of hydrogen positions in protein neutron crystallographic structures

    Article • Acta Crystallographica Section D Biological Crystallography, December 2011, International Union of Crystallography

    Dr Matthew P Blakeley

  73. Preliminary neutron crystallographic study of human transthyretin

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, October 2011, International Union of Crystallography

    Dr Matthew P Blakeley

  74. Active site protonation states of perdeuterated Toho-1 beta lactamase

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2011, International Union of Crystallography

    Dr Matthew P Blakeley

  75. High-resolution neutron diffraction on a tiny perdeuterated crystal

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2011, International Union of Crystallography

    Dr Matthew P Blakeley

  76. Large volume crystal growth in restricted geometry for neutron crystallography

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2011, International Union of Crystallography

    Dr Matthew P Blakeley

  77. Neutron high-resolution crystallographic study of perdeuteratedPyrococcus furiosusrubredoxin

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2011, International Union of Crystallography

    Dr Matthew P Blakeley

  78. Neutron structure of type-III antifreeze protein leads to ice interface model

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2011, International Union of Crystallography

    Dr Matthew P Blakeley

  79. Transthyretin amyloidosis – insights from neutron crystallography

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2011, International Union of Crystallography

    Dr Matthew P Blakeley

  80. X-ray and neutron crystallographic structure-based mechanism of archaeal inorganic pyrophophatase fromThermococcus thioreducins

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2011, International Union of Crystallography

    Dr Matthew P Blakeley

  81. Identification of the Elusive Hydronium Ion Exchanging Roles with a Proton in an Enzyme at Lower pH Values

    Article • Angewandte Chemie, May 2011, Wiley

    Dr Matthew P Blakeley

  82. Neutron structure of type-III antifreeze protein allows the reconstruction of AFP-ice interface

    Article • Journal of Molecular Recognition, April 2011, Wiley

    Dr Matthew P Blakeley

  83. The active site protonation states of perdeuterated Toho-1 β-lactamase determined by neutron diffraction support a role for Glu166 as the general base in acylation

    Article • FEBS Letters, December 2010, Wiley

    Dr Matthew P Blakeley

  84. Combined neutron and X-ray diffraction studies of DNA in crystals and solutions

    Article • Acta Crystallographica Section D Biological Crystallography, October 2010, International Union of Crystallography

    Dr Matthew P Blakeley

  85. Neutron macromolecular crystallography with LADI-III

    Article • Acta Crystallographica Section D Biological Crystallography, October 2010, International Union of Crystallography

    Dr Matthew P Blakeley

  86. Sweet neutron crystallography

    Article • Acta Crystallographica Section D Biological Crystallography, October 2010, International Union of Crystallography

    Dr Matthew P Blakeley

  87. Neutron diffraction structure of antifreeze protein leads to ice-binding model

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2010, International Union of Crystallography

    Dr Matthew P Blakeley

  88. Metal Ion Roles and the Movement of Hydrogen during Reaction Catalyzed by D-Xylose Isomerase: A Joint X-Ray and Neutron Diffraction Study

    Article • Structure, June 2010, Elsevier

    Dr Matthew P Blakeley

  89. Incorporation of methyl-protonated valine and leucine residues into deuterated ocean pout type III antifreeze protein: expression, crystallization and preliminary neutron diffraction studies

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, May 2010, International Union of Crystallography

    Dr Matthew P Blakeley

  90. Unambiguous determination of H-atom positions: comparing results from neutron and high-resolution X-ray crystallography

    Article • Acta Crystallographica Section D Biological Crystallography, April 2010, International Union of Crystallography

    Dr Matthew P Blakeley

  91. Neutron Diffraction Studies of a Class A β-Lactamase Toho-1 E166A/R274N/R276N Triple Mutant

    Article • Journal of Molecular Biology, March 2010, Elsevier

    Dr Pavel Afonine, Dr Matthew P Blakeley

  92. High-resolution X-ray and neutron data collection on antifreeze protein

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2009, International Union of Crystallography

    Dr Matthew P Blakeley

  93. Protonation state determination in proteins using high-resolution protein X-ray crystallography: effects of resolution and completeness

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2009, International Union of Crystallography

    Dr Matthew P Blakeley

  94. What is so sweet about neutron crystallography?

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2009, International Union of Crystallography

    Dr Matthew P Blakeley

  95. Characterization of image plates for neutron diffraction

    Article • Journal of Applied Crystallography, August 2009, International Union of Crystallography

    Dr Matthew P Blakeley

  96. Large crystal growth by thermal control allows combined X-ray and neutron crystallographic studies to elucidate the protonation states in Aspergillus flavus urate oxidase

    Article • Journal of The Royal Society Interface, July 2009, Royal Society Publishing

    Dr Matthew P Blakeley, Francoise Bonneté

  97. Neutron macromolecular crystallography

    Article • Crystallography Reviews, June 2009, Taylor & Francis

    Dr Matthew P Blakeley

  98. Perdeuteration, purification, crystallization and preliminary neutron diffraction of an ocean pout type III antifreeze protein

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, March 2009, International Union of Crystallography

    Dr Matthew P Blakeley

  99. A preliminary neutron diffraction study of γ-chymotrypsin

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, February 2009, International Union of Crystallography

    Dr Matthew P Blakeley

  100. A preliminary neutron crystallographic study of an A-DNA crystal

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, February 2009, International Union of Crystallography

    Dr Matthew P Blakeley

  101. A preliminary neutron crystallographic study of proteinase K at pD 6.5

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, January 2009, International Union of Crystallography

    Dr Matthew P Blakeley

  102. Neutron crystallography: opportunities, challenges, and limitations

    Article • Current Opinion in Structural Biology, October 2008, Elsevier

    Dr Matthew P Blakeley

  103. Joint neutron and X-ray diffraction studies at 293 K of antifreeze protein

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2008, International Union of Crystallography

    Dr Matthew P Blakeley

  104. Neutron crystallographic analysis of deuterated and selectively CH3-protonated deuterated rubredoxin

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2008, International Union of Crystallography

    Dr Matthew P Blakeley

  105. Neutron macromolecular crystallography using the Laue diffractometer LADI-III

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2008, International Union of Crystallography

    Dr Matthew P Blakeley

  106. Preliminary neutron crystallographic analysis of selectively CH3-protonated deuterated rubredoxin fromPyrococcus furiosus

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, May 2008, International Union of Crystallography

    Dr Matthew P Blakeley

  107. A preliminary neutron crystallographic study of thaumatin

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, April 2008, International Union of Crystallography

    Dr Matthew P Blakeley

  108. New sources and instrumentation for neutrons in biology

    Article • Chemical Physics, April 2008, Elsevier

    Dr Matthew P Blakeley

  109. Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase

    Article • Proceedings of the National Academy of Sciences, February 2008, Proceedings of the National Academy of Sciences

    Dr Pavel Afonine, Dr Matthew P Blakeley

  110. The determination of protonation states in proteins

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2007, International Union of Crystallography

    Dr Matthew P Blakeley

  111. The determination of protonation states in proteins

    Article • Acta Crystallographica Section D Biological Crystallography, July 2007, International Union of Crystallography

    Professor John Richard Helliwell, Dr Matthew P Blakeley

  112. Ultra high resolution X-ray and neutron diffraction studies of fully deuterated aldose reductase show a catalytic proton pathway

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2006, International Union of Crystallography

    Dr Matthew P Blakeley

  113. Neutron Laue macromolecular crystallography

    Article • European Biophysics Journal, August 2006, Springer Science + Business Media

    Dr Matthew P Blakeley

  114. Comparison of hydrogen determination with X-ray and neutron crystallography in a human aldose reductase–inhibitor complex

    Article • European Biophysics Journal, April 2006, Springer Science + Business Media

    Dr Matthew P Blakeley

  115. A preliminary neutron diffraction study of rasburicase, a recombinant urate oxidase enzyme, complexed with 8-azaxanthin

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, February 2006, International Union of Crystallography

    Dr Matthew P Blakeley, Francoise Bonneté

  116. High-resolution neutron protein crystallography with radically small crystal volumes: application of perdeuteration to human aldose reductase

    Article • Acta Crystallographica Section D Biological Crystallography, September 2005, International Union of Crystallography

    Dr Matthew P Blakeley

  117. Neutron cryocrystallography of proteins

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2005, International Union of Crystallography

    Dr Matthew P Blakeley

  118. Neutron protein crystallography (nPX) development: higher molecular weight capability

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2005, International Union of Crystallography

    Dr Matthew P Blakeley

  119. Structural studies on human α-thrombin

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2005, International Union of Crystallography

    Dr Matthew P Blakeley

  120. The 15-K neutron structure of saccharide-free concanavalin A

    Article • Proceedings of the National Academy of Sciences, November 2004, Proceedings of the National Academy of Sciences

    Professor John Richard Helliwell, Dr Matthew P Blakeley

  121. Neutron diffraction structure of fully deuterated aldose reductase: a necessary complement to X-ray ultra-high-resolution structures

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2004, International Union of Crystallography

    Dr Matthew P Blakeley

  122. Neutron protein structures at 12 K

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2004, International Union of Crystallography

    Dr Matthew P Blakeley

  123. Synchrotron and neutron techniques in biological crystallography

    Article • Chemical Society Reviews, January 2004, Royal Society of Chemistry

    Professor John Richard Helliwell, Dr Matthew P Blakeley