All Stories

  1. An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein

    Article • PLoS ONE, August 2017, PLOS

    Matteo Stravalaci

  2. Humanin Specifically Interacts with Amyloid-β Oligomers and Counteracts Their in vivo Toxicity

    Article • Journal of Alzheimer’s Disease, April 2017, IOS Press

    Matteo Stravalaci

  3. Fingolimod Limits Acute Aβ Neurotoxicity and Promotes Synaptic Versus Extrasynaptic NMDA Receptor Functionality in Hippocampal Neurons

    Article • Scientific Reports, January 2017, Nature

    Matteo Stravalaci

  4. An antibody specific for prion protein detects toxic amyloid-beta oligomers

    Article • Journal of Alzheimer’s Disease, August 2016, IOS Press

    Matteo Stravalaci, Dr. Marco Gobbi

  5. A relevant pharmacological target in TBI

    Article • Journal of Cerebral Blood Flow & Metabolism, July 2016, SAGE Publications

    Maria-Grazia De Simoni, Matteo Stravalaci, Professor Anna Bernardi

  6. A New Surface Plasmon Resonance Assay for In Vitro Screening of Mannose-Binding Lectin Inhibitors

    Article • SLAS DISCOVERY, July 2016, SAGE Publications

    Matteo Stravalaci, Dr. Marco Gobbi, Professor Anna Bernardi

  7. The new β amyloid-derived peptide Aβ1–6A2V-TAT(D) prevents Aβ oligomer formation and protects transgenic C. elegans from Aβ toxicity

    Article • Neurobiology of Disease, April 2016, Elsevier

    Matteo Stravalaci

  8. A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein

    Article • Scientific Reports, March 2016, Nature

    Matteo Stravalaci

  9. Clusterin Binds to Aβ1–42Oligomers with High Affinity and Interferes with Peptide Aggregation by Inhibiting Primary and Secondary Nucleation

    Article • Journal of Biological Chemistry, February 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Matteo Stravalaci

  10. Scaffold Optimisation of Tetravalent Antagonists of the Mannose Binding Lectin

    Article • Chemistry - A European Journal, January 2016, Wiley

    Professor Anna Bernardi, Matteo Stravalaci

  11. Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: a novel pharmacological strategy against brain injury

    Article • Cell Death and Disease, August 2015, Nature

    Matteo Stravalaci

  12. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode

    Article • Journal of Experimental Medicine, May 2015, Rockefeller University Press

    Matteo Stravalaci

  13. CLUSTERIN REDUCES THE FORMATION OF BIOLOGICAL RELEVANT TOXIC SOLUBLE ABETA1-42 OLIGOMERS

    Article • Alzheimer s & Dementia, July 2014, Elsevier

    Matteo Stravalaci

  14. A New Surface Plasmon Resonance-Based Immunoassay for Rapid, Reproducible and Sensitive Quantification of Pentraxin-3 in Human Plasma

    Article • Sensors, June 2014, MDPI AG

    Matteo Stravalaci

  15. Expression of A2V-mutated Aβ in Caenorhabditis elegans results in oligomer formation and toxicity

    Article • Neurobiology of Disease, February 2014, Elsevier

    Matteo Stravalaci

  16. Novel approaches for studying amyloidogenic peptides/proteins

    Article • Current Opinion in Pharmacology, October 2013, Elsevier

    Matteo Stravalaci

  17. Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases

    Article • Biochemical Journal, September 2013, Portland Press Ltd.

    Matteo Stravalaci

  18. New insights into the molecular mechanisms underlying sensitivity/resistance to the atypical retinoid ST1926 in acute myeloid leukaemia cells: The role of histone H2A.Z, cAMP-dependent protein kinase A and the proteasome

    Article • European Journal of Cancer, April 2013, Elsevier

    Matteo Stravalaci

  19. An N-terminal Fragment of the Prion Protein Binds to Amyloid-β Oligomers and Inhibits Their Neurotoxicityin Vivo

    Article • Journal of Biological Chemistry, January 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Matteo Stravalaci

  20. Good gene, bad gene: New APP variant may be both

    Article • Progress in Neurobiology, December 2012, Elsevier

    Matteo Stravalaci

  21. Applications of Surface Plasmon Resonance (SPR) for the Characterization of Nanoparticles Developed for Biomedical Purposes

    Article • Sensors, November 2012, MDPI AG

    Matteo Stravalaci

  22. Targeting Mannose-Binding Lectin Confers Long-Lasting Protection With a Surprisingly Wide Therapeutic Window in Cerebral Ischemia

    Article • Circulation, August 2012, Wolters Kluwer Health

    Professor Anna Bernardi, Matteo Stravalaci

  23. Detection of toxic amyloid beta oligomers by a novel Surface Plasmon Resonance-based immunoassay

    Article • Journal of Biological Chemistry, June 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Matteo Stravalaci

  24. Alternative Pathway Activation of Complement by Shiga Toxin Promotes Exuberant C3a Formation That Triggers Microvascular Thrombosis

    Article • The Journal of Immunology, June 2011, The American Association of Immunologists

    Matteo Stravalaci

  25. A modified protocol to prepare seed-free starting solutions of amyloid-β (Aβ)1–40 and Aβ1–42 from the corresponding depsipeptides

    Article • Analytical Biochemistry, April 2011, Elsevier

    Matteo Stravalaci

  26. Use of surface plasmon resonance to study the elongation kinetics and the binding properties of the highly amyloidogenic Aβ1–42 peptide, synthesized by depsi-peptide technique

    Article • Biosensors and Bioelectronics, January 2011, Elsevier

    Matteo Stravalaci

  27. Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin‐binding adhesins fibronectin‐binding protein A and fibronectin‐binding protein B from Staphylococcus aureus

    Article • FEBS Journal, September 2010, Wiley

    Pietro Speziale, Matteo Stravalaci

  28. Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein

    Article • Proceedings of the National Academy of Sciences, January 2010, Proceedings of the National Academy of Sciences

    Matteo Stravalaci

  29. Non-peptidic Thrombospondin-1 Mimics as Fibroblast Growth Factor-2 Inhibitors

    Article • Journal of Biological Chemistry, January 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Matteo Stravalaci

  30. Immunopurification of Pathological Prion Protein Aggregates

    Article • PLoS ONE, November 2009, PLOS

    Matteo Stravalaci

  31. Recombinant C1 inhibitor in brain ischemic injury

    Article • Annals of Neurology, September 2009, Wiley

    Matteo Stravalaci