All Stories

  1. Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules

    Article • Nature Immunology, January 2022, Springer Science + Business Media

    Mariagrazia Uguccioni

  2. Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases

    Article • Scientific Reports, November 2021, Springer Science + Business Media

    Mariagrazia Uguccioni

  3. Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction

    Article • Journal of Medicinal Chemistry, September 2021, American Chemical Society (ACS)

    Mariagrazia Uguccioni

  4. HMGB1 promotes CXCL12‐dependent egress of murine B cells from Peyer's patches in homeostasis

    Article • European Journal of Immunology, June 2021, Wiley

    Mariagrazia Uguccioni

  5. Risk assessment and seroprevalence of SARS-CoV-2 infection in healthcare workers of COVID-19 and non-COVID-19 hospitals in Southern Switzerland

    Article • The Lancet Regional Health - Europe, February 2021, Elsevier

    Mariagrazia Uguccioni

  6. B cell zone reticular cell microenvironments shape CXCL13 gradient formation

    Article • Nature Communications, July 2020, Springer Science + Business Media

    Professor Daniel F Legler, Mariagrazia Uguccioni

  7. ACKR4 Recruits GRK3 Prior to β-Arrestins but Can Scavenge Chemokines in the Absence of β-Arrestins

    Article • Frontiers in Immunology, April 2020, Frontiers

    Professor Daniel F Legler, Mariagrazia Uguccioni

  8. Oxidation State Dependent Conformational Changes of HMGB1 Regulate the Formation of the CXCL12/HMGB1 Heterocomplex

    Article • Computational and Structural Biotechnology Journal, January 2019, Elsevier

    Mariagrazia Uguccioni

  9. Lidocaine inhibits cytoskeletal remodelling and human breast cancer cell migration

    Article • British Journal of Anaesthesia, October 2018, Elsevier

    Mariagrazia Uguccioni

  10. Chemokine Heterocomplexes and Cancer: A Novel Chapter to Be Written in Tumor Immunity

    Article • Frontiers in Immunology, September 2018, Frontiers

    Mariagrazia Uguccioni

  11. Redox-Mediated Mechanisms Fuel Monocyte Responses to CXCL12/HMGB1 in Active Rheumatoid Arthritis

    Article • Frontiers in Immunology, September 2018, Frontiers

    Mariagrazia Uguccioni

  12. Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis

    Article • June 2018, Springer Science + Business Media

    Mariagrazia Uguccioni

  13. Insight on the regulation of chemokine activities

    Article • Journal of Leukocyte Biology, April 2018, Wiley

    Mariagrazia Uguccioni

  14. Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination

    Article • Frontiers in Immunology, November 2017, Frontiers

    Mariagrazia Uguccioni

  15. Chemokine activity modulation

    Article • The FASEB Journal, July 2017, Federation of American Societies For Experimental Biology (FASEB)

    Cesar Santiago, Mariagrazia Uguccioni, Dr Yoan R. Monneau, Professor Daniel F Legler, Mario Melado

  16. Editorial: Regulation of Inflammation, Its Resolution and Therapeutic Targeting

    Article • Frontiers in Immunology, April 2017, Frontiers

    Mariagrazia Uguccioni

  17. Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes Dendritic Cell Function in the Draining Lymph Node

    Article • Cell Reports, March 2017, Elsevier

    Mariagrazia Uguccioni

  18. Impairment of CCR6 + and CXCR3 + Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization

    Article • The Journal of Immunology, November 2016, The American Association of Immunologists

    Mariagrazia Uguccioni

  19. Modulation of Chemokine Responses: Synergy and Cooperativity

    Article • Frontiers in Immunology, May 2016, Frontiers

    Mariagrazia Uguccioni

  20. Potential of PEGylated Toll-Like Receptor 7 Ligands for Controlling Inflammation and Functional Changes in Mouse Models of Asthma and Silicosis

    Article • Frontiers in Immunology, March 2016, Frontiers

    Mariagrazia Uguccioni

  21. Function of Chemokines and Their Receptors in Immunity

    Article • January 2016, Elsevier

    Mariagrazia Uguccioni

  22. Chemokine interaction with synergy-inducing molecules: fine tuning modulation of cell trafficking

    Article • Journal of Leukocyte Biology, December 2015, Society for Leukocyte Biology

    Mariagrazia Uguccioni

  23. Immune Cells, Recruitment and Localization of

    Article • June 2015, Springer Science + Business Media

    Mariagrazia Uguccioni

  24. Innate immune cells express IL-17A/F in acute generalized exanthematous pustulosis and generalized pustular psoriasis

    Article • Archives of Dermatological Research, July 2014, Springer Science + Business Media

    Mariagrazia Uguccioni

  25. HMGB1 and leukocyte migration during trauma and sterile inflammation

    Article • Molecular Immunology, August 2013, Elsevier

    Mariagrazia Uguccioni

  26. Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

    Article • The Journal of Experimental Medicine, August 2012, Rockefeller University Press

    Mariagrazia Uguccioni

  27. Chemokines in immunopathology: From dark sides to clinical translation

    Article • Immunology Letters, July 2012, Elsevier

    Mariagrazia Uguccioni

  28. Possible mechanisms involved in chemokine synergy fine tuning the inflammatory response

    Article • Immunology Letters, July 2012, Elsevier

    Mariagrazia Uguccioni

  29. Role of lymphoid chemokines in the development of functional ectopic lymphoid structures in rheumatic autoimmune diseases

    Article • Immunology Letters, July 2012, Elsevier

    Mariagrazia Uguccioni

  30. HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

    Article • The Journal of Experimental Medicine, February 2012, Rockefeller University Press

    Mariagrazia Uguccioni

  31. Perivascular expression of CXCL9 and CXCL12 in primary central nervous system lymphoma: T-cell infiltration and positioning of malignant B cells

    Article • International Journal of Cancer, April 2010, Wiley

    Dr Francesco Bertoni, Mariagrazia Uguccioni

  32. Synthetic Double-Stranded RNAs Are Adjuvants for the Induction of T Helper 1 and Humoral Immune Responses to Human Papillomavirus in Rhesus Macaques

    Article • PLoS Pathogens, April 2009, PLOS

    Mariagrazia Uguccioni

  33. Synergy-inducing chemokines enhance CCR2 ligand activities on monocytes

    Article • European Journal of Immunology, April 2009, Wiley

    Mariagrazia Uguccioni

  34. Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint

    Article • Arthritis & Rheumatism, November 2008, Wiley

    Mariagrazia Uguccioni

  35. Identification of CXCL13 as a new marker for follicular dendritic cell sarcoma

    Article • The Journal of Pathology, November 2008, Wiley

    Mariagrazia Uguccioni

  36. Lymphocyte homing and immunology of extranodal lymphoid tissues

    Article • July 2008, Taylor & Francis

    Mariagrazia Uguccioni

  37. The central nervous system in mucosal vaccination of rhesus macaques with simian immunodeficiency virus Δnef

    Article • Neuropathology and Applied Neurobiology, December 2007, Wiley

    Mariagrazia Uguccioni

  38. CCL21 Expression Pattern of Human Secondary Lymphoid Organ Stroma Is Conserved in Inflammatory Lesions with Lymphoid Neogenesis

    Article • American Journal Of Pathology, November 2007, Elsevier

    Mariagrazia Uguccioni

  39. A single vaccination with attenuated SIVmac 239 via the tonsillar route confers partial protection against challenge with SIVmac 251 at a distant mucosal site, the rectum

    Article • Frontiers in Bioscience, January 2007, IMR Press

    Mariagrazia Uguccioni

  40. CD molecules 2005: human cell differentiation molecules

    Article • Blood, November 2005, American Society of Hematology

    Mariagrazia Uguccioni

  41. Systematic microanatomical analysis of CXCL13 and CCL21in situ production and progressive lymphoid organization in rheumatoid synovitis

    Article • European Journal of Immunology, May 2005, Wiley

    Mariagrazia Uguccioni

  42. A rich chemokine environment strongly enhances leukocyte migration and activities

    Article • Blood, May 2005, American Society of Hematology

    Mariagrazia Uguccioni

  43. CCL22-induced responses are powerfully enhanced by synergy inducing chemokines via CCR4: evidence for the involvement of first ?-strand of chemokine

    Article • European Journal of Immunology, March 2005, Wiley

    Mariagrazia Uguccioni

  44. Prostaglandin E2 modulates the functional responsiveness of human monocytes to chemokines

    Article • European Journal of Immunology, December 2004, Wiley

    Mariagrazia Uguccioni

  45. I-TAC/CXCL11 is a natural antagonist for CCR5

    Article • Journal of Leukocyte Biology, June 2004, Oxford University Press (OUP)

    Mariagrazia Uguccioni

  46. Eotaxin-3/CCL26 Is a Natural Antagonist for CC Chemokine Receptors 1 and 5

    Article • Journal of Biological Chemistry, March 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Mariagrazia Uguccioni

  47. CXC and CC chemokine expression in inflamed and noninflamed pelvic ileal pouch tissue

    Article • International Journal of Colorectal Disease, March 2004, Springer Science + Business Media

    Mariagrazia Uguccioni

  48. Secondary Lymphoid Tissue Chemokine (CCL21) Is Upregulated in Allergic Contact Dermatitis

    Article • International Archives of Allergy and Immunology, February 2004, Karger Publishers

    Mariagrazia Uguccioni

  49. A role for chemokines in the induction of chondrocyte phenotype modulation

    Article • Arthritis & Rheumatism, January 2004, Wiley

    Mariagrazia Uguccioni

  50. Regulation of Dendritic Cell Migration to the Draining Lymph Node

    Article • The Journal of Experimental Medicine, August 2003, Rockefeller University Press

    Mariagrazia Uguccioni

  51. Eotaxin-3 is a natural antagonist for CCR2 and exerts a repulsive effect on human monocytes

    Article • Blood, August 2003, American Society of Hematology

    Mariagrazia Uguccioni

  52. Expression of CS-1 fibronectin precedes monocyte chemoattractant protein-1 production during elicitation of allergic contact dermatitis

    Article • Clinical & Experimental Allergy, August 2003, Wiley

    Mariagrazia Uguccioni

  53. Chronic ‘Immunological’ Rhinosinusitis: General Aspects, Cytokines, Chemokines and Possible Therapeutic Consequences

    Article • Oto-Rhino-Laryngologia Nova, July 2003, Karger Publishers

    Mariagrazia Uguccioni

  54. Macrophages exposed to Mycobacterium tuberculosis release chemokines able to recruit selected leucocyte subpopulations: focus on gammadelta cells

    Article • Immunology, March 2003, Wiley

    Mariagrazia Uguccioni

  55. Expression of B-cell–attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma

    Article • Blood, February 2003, American Society of Hematology

    Mariagrazia Uguccioni

  56. Growth-related oncogene ? induction of apoptosis in osteoarthritis chondrocytes

    Article • Arthritis & Rheumatism, December 2002, Wiley

    Mariagrazia Uguccioni

  57. CD antigens 2002

    Article • Blood, May 2002, American Society of Hematology

    Mariagrazia Uguccioni

  58. CD Antigens 2001

    Article • Modern Pathology, January 2002, Nature

    Mariagrazia Uguccioni

  59. CD antigens 2001

    Article • Tissue Antigens, December 2001, Wiley

    Mariagrazia Uguccioni

  60. CD Antigens 2001: Aims and Results of HLDA Workshops

    Article • Stem Cells, November 2001, Wiley

    Mariagrazia Uguccioni

  61. CD antigens 2001

    Article • European Journal of Immunology, October 2001, Wiley

    Mariagrazia Uguccioni

  62. CD antigens 2001

    Article • International Immunology, September 2001, Oxford University Press (OUP)

    Mariagrazia Uguccioni

  63. CD antigens 2001

    Article • Immunology, August 2001, Wiley

    Mariagrazia Uguccioni

  64. CD Antigens 2001

    Article • Cellular Immunology, August 2001, Elsevier

    Mariagrazia Uguccioni

  65. Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5

    Article • Blood, April 2001, American Society of Hematology

    Mariagrazia Uguccioni

  66. CC chemokines and the receptors CCR3 and CCR5 are differentially expressed in the nonneoplastic leukocytic infiltrates of Hodgkin disease

    Article • Blood, March 2001, American Society of Hematology

    Mariagrazia Uguccioni

  67. Cell cycle–dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity

    Article • Journal of Clinical Investigation, January 2001, American Society for Clinical Investigation

    Mariagrazia Uguccioni

  68. Macrophages infiltrating the tissue in chronic pancreatitis express the chemokine receptor CCR5

    Article • Surgery, November 2000, Elsevier

    Mariagrazia Uguccioni

  69. Chemokine expression in pouchitis

    Article • Digestive and Liver Disease, November 2000, Elsevier

    Mariagrazia Uguccioni

  70. Human chondrocytes express functional chemokine receptors and release matrix-degrading enzymes in response to C-X-C and C-C chemokines

    Article • Arthritis & Rheumatism, August 2000, Wiley

    Mariagrazia Uguccioni

  71. MCP-3 in inflammatory bowel disease Reply

    Article • Gut, July 2000, BMJ

    Mariagrazia Uguccioni

  72. Chemokine expression in pouchitis

    Article • Digestive and Liver Disease, May 2000, Elsevier

    Mariagrazia Uguccioni

  73. CXC and CC chemokine expression in inflamed and non-inflamed pelvic ileal pouch tissue

    Article • Gastroenterology, April 2000, Elsevier

    Mariagrazia Uguccioni

  74. Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation

    Article • Current Biology, March 2000, Elsevier

    Mariagrazia Uguccioni

  75. BCA-1 is highly expressed in Helicobacter pylori–induced mucosa-associated lymphoid tissue and gastric lymphoma

    Article • Journal of Clinical Investigation, November 1999, American Society for Clinical Investigation

    Mariagrazia Uguccioni

  76. Increased Expression of IP-10, IL-8, MCP-1, and MCP-3 in Ulcerative Colitis

    Article • American Journal Of Pathology, August 1999, Elsevier

    Mariagrazia Uguccioni

  77. Enhanced Expression of Eotaxin and CCR3 in Atopic Dermatitis

    Article • Journal of Investigative Dermatology, July 1999, Elsevier

    Mariagrazia Uguccioni

  78. Chemokines and chemokine receptors in allergic diseases

    Article • Pediatric Pulmonology, January 1999, Wiley

    Mariagrazia Uguccioni

  79. Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis

    Article • Arthritis & Rheumatism, December 1998, Wiley

    Mariagrazia Uguccioni

  80. Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis

    Article • Arthritis & Rheumatism, December 1998, Wiley

    Mariagrazia Uguccioni

  81. CXC and CC chemokine expression in ulcerative colitis

    Article • Gastroenterology, April 1998, Elsevier

    Mariagrazia Uguccioni

  82. Chemokine Expression in Heart Transplantation

    Article • Journal of the American College of Cardiology, February 1998, Elsevier

    Mariagrazia Uguccioni

  83. Chemokines and Chemokine Receptors in Allergic Inflammation

    Article • January 1998, Elsevier

    Mariagrazia Uguccioni

  84. CCR5 is characteristic of Th1 lymphocytes

    Article • Nature, January 1998, Springer Science + Business Media

    Mariagrazia Uguccioni

  85. Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils

    Article • Current Biology, November 1997, Elsevier

    Mariagrazia Uguccioni

  86. High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines.

    Article • Journal of Clinical Investigation, September 1997, American Society for Clinical Investigation

    Mariagrazia Uguccioni

  87. Eotaxin-2, a Novel CC Chemokine that Is Selective for the Chemokine Receptor CCR3, and Acts Like Eotaxin on Human Eosinophil and Basophil Leukocytes

    Article • The Journal of Experimental Medicine, June 1997, Rockefeller University Press

    Mariagrazia Uguccioni

  88. CKβ8, a novel CC chemokine that predominantly acts on monocytes

    Article • FEBS Letters, May 1997, Wiley

    Mariagrazia Uguccioni

  89. Synovial expression of cell adhesion molecules in polymyalgia rheumatica

    Article • Clinical & Experimental Immunology, March 1997, Oxford University Press (OUP)

    Mariagrazia Uguccioni

  90. Leukocyte infiltration in synovial tissue from the shoulder of patients with polymyalgia rheumatica. Quantitative analysis and influence of corticosteroid treatment

    Article • Arthritis & Rheumatism, July 1996, Wiley

    Mariagrazia Uguccioni

  91. RANTES and MCP-3 Antagonists Bind Multiple Chemokine Receptors

    Article • Journal of Biological Chemistry, May 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Mariagrazia Uguccioni

  92. Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin

    Article • The Journal of Experimental Medicine, May 1996, Rockefeller University Press

    Mariagrazia Uguccioni

  93. Deletion of the NH2-terminal residue converts monocyte chemotactic protein 1 from an activator of basophil mediator release to an eosinophil chemoattractant.

    Article • The Journal of Experimental Medicine, February 1996, Rockefeller University Press

    Mariagrazia Uguccioni

  94. HCC-1, a novel chemokine from human plasma.

    Article • The Journal of Experimental Medicine, January 1996, Rockefeller University Press

    Mariagrazia Uguccioni

  95. PI 3-Kinase-Dependent and Independent Chemotaxis of Human Neutrophil Leukocytes

    Article • Biochemical and Biophysical Research Communications, December 1995, Elsevier

    Mariagrazia Uguccioni

  96. Endothelin-1 in idiopathic pulmonary fibrosis.

    Article • Journal of Clinical Pathology, April 1995, BMJ

    Mariagrazia Uguccioni

  97. Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1α and MIP-1β on human monocytes

    Article • European Journal of Immunology, January 1995, Wiley

    Mariagrazia Uguccioni

  98. Cytokine Production in Felty’s Syndrome

    Article • January 1993, Springer Science + Business Media

    Mariagrazia Uguccioni

  99. IL-8 Concentration in β-Thalassaemia and After Bone Marrow Transplantation

    Article • January 1993, Springer Science + Business Media

    Mariagrazia Uguccioni

  100. Serum markers of immune activation and liver allograft rejection

    Article • Digestive Diseases and Sciences, July 1992, Springer Science + Business Media

    Mariagrazia Uguccioni, Enzo Lalli

  101. Intracellular nucleotides of lymphocytes and granulocytes from normal ageing subjects

    Article • Mechanisms of Ageing and Development, June 1992, Elsevier

    Mariagrazia Uguccioni

  102. Serum amyloid A protein concentration in bone marrow transplantation for beta thalassaemia.

    Article • Journal of Clinical Pathology, April 1992, BMJ

    Mariagrazia Uguccioni

  103. T-CELL RECEPTOR GAMMA-DELTA POSITIVE LYMPHOCYTES IN SYNOVIAL MEMBRANE

    Article • Rheumatology, January 1992, Oxford University Press (OUP)

    Mariagrazia Uguccioni

  104. Increased serum concentrations of tumour necrosis factor in beta thalassaemia: effect of bone marrow transplantation.

    Article • Journal of Clinical Pathology, January 1992, BMJ

    Mariagrazia Uguccioni

  105. Natural chemokine antagonism and synergism

    Article • Springer Science + Business Media

    Mariagrazia Uguccioni