All Stories

  1. Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses

    Article • Proceedings of the National Academy of Sciences, March 2024, Proceedings of the National Academy of Sciences

    Professor Masao Matsuoka

  2. In vivo dynamics and adaptation of HTLV-1-infected clones under different clinical conditions

    Article • PLoS Pathogens, February 2021, PLOS

    Professor Masao Matsuoka

  3. HTLV-1 bZIP factor: the key viral gene for pathogenesis

    Article • Retrovirology, January 2020, Springer Science + Business Media

    Professor Masao Matsuoka

  4. Clinical potential of dual-energy cardiac CT in cardiac amyloidosis

    Article • Amyloid, March 2019, Taylor & Francis

    Kenichi Tsujita, Professor Masao Matsuoka

  5. The history and future of HTLV-1 research

    Article • F1000Research, February 2019, Faculty of 1000, Ltd.

    Professor Masao Matsuoka, Dr. Yutaka Tagaya

  6. CADM1 is a diagnostic marker in early-stage mycosis fungoides: Multicenter study of 58 cases

    Article • Journal of the American Academy of Dermatology, December 2018, Elsevier

    Professor Masao Matsuoka

  7. Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate

    Article • Scientific Reports, October 2018, Springer Science + Business Media

    Professor Masao Matsuoka

  8. Safety of mogamulizumab for relapsed ATL after allogeneic hematopoietic cell transplantation

    Article • Bone Marrow Transplantation, August 2018, Springer Science + Business Media

    Professor Masao Matsuoka

  9. Pancytopenia and Myelodysplastic Changes in Aceruloplasminemia: A Case with a Novel Pathogenic Variant in the Ceruloplasmin Gene

    Article • Internal Medicine, July 2018, Japanese Society of Internal Medicine

    Professor Masao Matsuoka

  10. HTLV-1 Alters T Cells for Viral Persistence and Transmission

    Article • Frontiers in Microbiology, March 2018, Frontiers

    Professor Masao Matsuoka

  11. Mogamulizumab (Anti-CCR4) in HTLV-1–Associated Myelopathy

    Article • New England Journal of Medicine, February 2018, New England Journal of Medicine (NEJM/MMS)

    Professor Masao Matsuoka

  12. Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells

    Article • Proceedings of the National Academy of Sciences, January 2018, Proceedings of the National Academy of Sciences

    Professor Masao Matsuoka

  13. Isolated Pancreatic Myeloid Sarcoma Associated with t(8;21)/RUNX1-RUNX1T1 Rearrangement

    Article • Internal Medicine, January 2018, Japanese Society of Internal Medicine

    Professor Masao Matsuoka

  14. Oncogenic spiral by infectious pathogens: Cooperation of multiple factors in cancer development

    Article • Cancer Science, December 2017, Wiley

    Professor Masao Matsuoka

  15. Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway

    Article • Nature Communications, December 2017, Springer Science + Business Media

    Professor Masao Matsuoka

  16. Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo

    Article • PLoS Pathogens, November 2017, PLOS

    Professor Masao Matsuoka

  17. Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma

    Article • Blood, October 2017, American Society of Hematology

    Professor Masao Matsuoka

  18. HTLV-1 bZIP factor suppresses TDP1 expression through inhibition of NRF-1 in adult T-cell leukemia

    Article • Scientific Reports, October 2017, Springer Science + Business Media

    Professor Masao Matsuoka

  19. Human T-cell leukaemia virus type 1: parasitism and pathogenesis

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, September 2017, Royal Society Publishing

    Professor Masao Matsuoka

  20. HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors

    Article • PLoS Pathogens, January 2017, PLOS

    Professor Masao Matsuoka

  21. Reducing the global burden of HTLV-1 infection: An agenda for research and action

    Article • Antiviral Research, January 2017, Elsevier

    Professor Masao Matsuoka

  22. Screening transplant donors for HTLV-1 and -2

    Article • Blood, November 2016, American Society of Hematology

    Professor Masao Matsuoka

  23. An IL‐27/Stat3 axis induces expression of programmed cell death 1 ligands ( PD ‐L1/2) on infiltrating macrophages in lymphoma

    Article • Cancer Science, November 2016, Wiley

    Professor Masao Matsuoka

  24. Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors

    Article • Retrovirology, September 2016, Springer Science + Business Media

    Professor Masao Matsuoka

  25. HTLV-1 Viral Factor HBZ Induces CCR4 to Promote T-cell Migration and Proliferation

    Article • Cancer Research, July 2016, American Association for Cancer Research (AACR)

    Professor Masao Matsuoka

  26. TIM-3 expression in lymphoma cells predicts chemoresistance in patients with adult T-cell leukemia/lymphoma

    Article • Oncology Letters, June 2016, Spandidos Publications

    Professor Masao Matsuoka

  27. Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse model

    Article • Oncotarget, June 2016, Impact Journals, LLC

    Professor Masao Matsuoka

  28. Enhancement of anti-STLV-1/HTLV-1 immune responses through multimodal effects of anti-CCR4 antibody

    Article • Scientific Reports, June 2016, Springer Science + Business Media

    Professor Masao Matsuoka

  29. Multifaceted functions and roles of HBZ in HTLV-1 pathogenesis

    Article • Retrovirology, March 2016, Springer Science + Business Media

    Professor Masao Matsuoka

  30. Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour

    Article • Nature Communications, February 2016, Springer Science + Business Media

    Professor Masao Matsuoka

  31. HTLV-1 bZIP factor protein targets the Rb/E2F-1 pathway to promote proliferation and apoptosis of primary CD4+ T cells

    Article • Oncogene, January 2016, Springer Science + Business Media

    Professor Masao Matsuoka

  32. HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT)

    Article • PLoS Pathogens, January 2016, PLOS

    Professor Masao Matsuoka

  33. HTLV-1 subgroups associated with the risk of HAM/TSP are related to viral and host gene expression in peripheral blood mononuclear cells, independent of the transactivation functions of the viral factors

    Article • Journal of NeuroVirology, December 2015, Springer Science + Business Media

    Professor Masao Matsuoka

  34. Correction: Interferon-γ Promotes Inflammation and Development of T-Cell Lymphoma in HTLV-1 bZIP Factor Transgenic Mice

    Article • PLoS Pathogens, October 2015, PLOS

    Professor Masao Matsuoka

  35. Integrated molecular analysis of adult T cell leukemia/lymphoma

    Article • Nature Genetics, October 2015, Springer Science + Business Media

    Professor Masao Matsuoka

  36. Impact of HIV-1 infection pathways on susceptibility to antiviral drugs and on virus spread

    Article • Virology, October 2015, Elsevier

    Kazuya SHIMURA, Professor Masao Matsuoka

  37. HTLV-1 bZIP Factor RNA and Protein Impart Distinct Functions on T-cell Proliferation and Survival

    Article • Cancer Research, September 2015, American Association for Cancer Research (AACR)

    Professor Masao Matsuoka

  38. Experimental evaluation of the zoonotic infection potency of simian retrovirus type 4 using humanized mouse model

    Article • Scientific Reports, September 2015, Springer Science + Business Media

    Professor Masao Matsuoka

  39. Interferon-γ Promotes Inflammation and Development of T-Cell Lymphoma in HTLV-1 bZIP Factor Transgenic Mice

    Article • PLoS Pathogens, August 2015, PLOS

    Professor Masao Matsuoka

  40. Protective effect of cytotoxic T lymphocytes targeting HTLV-1 bZIP factor

    Article • Blood, June 2015, American Society of Hematology

    Professor Masao Matsuoka

  41. Identification of anti-HIV agents with a novel benzo[4,5]isothiazolo[2,3-a]pyrimidine scaffold

    Article • Bioorganic & Medicinal Chemistry, April 2015, Elsevier

    Kazuya SHIMURA, Professor Masao Matsuoka

  42. Human T ‐cell leukemia virus type 1 T ax oncoprotein represses the expression of the BCL 11 B tumor suppressor in T ‐cells

    Article • Cancer Science, March 2015, Wiley

    Professor Masao Matsuoka

  43. TCF1 and LEF1 act as T-cell intrinsic HTLV-1 antagonists by targeting Tax

    Article • Proceedings of the National Academy of Sciences, February 2015, Proceedings of the National Academy of Sciences

    Professor Masao Matsuoka

  44. Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study

    Article • British Journal of Haematology, January 2015, Wiley

    Professor Masao Matsuoka

  45. Investigations of possible prodrug structures for 2-(2-mercaptophenyl)tetrahydropyrimidines: reductive conversion from anti-HIV agents with pyrimidobenzothiazine and isothiazolopyrimidine scaffolds

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Dr Shinya Oishi, Professor Masao Matsuoka

  46. Reevaluation of confirmatory tests for human T-cell leukemia virus Type 1 using a luciferase immunoprecipitation system in blood donors

    Article • Transfusion, November 2014, Wiley

    Professor Masao Matsuoka

  47. A Critical Role for IL-17RB Signaling in HTLV-1 Tax-Induced NF-κB Activation and T-Cell Transformation

    Article • PLoS Pathogens, October 2014, PLOS

    Professor Masao Matsuoka

  48. Development of T cell lymphoma in HTLV-1 bZIP factor and Tax double transgenic mice

    Article • Archives of Virology, May 2014, Springer Science + Business Media

    Professor Masao Matsuoka

  49. Human T-cell leukemia virus type 1 and Foxp3 expression: viral strategy in vivo

    Article • International Immunology, May 2014, Oxford University Press (OUP)

    Professor Masao Matsuoka

  50. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma

    Article • Blood, April 2014, American Society of Hematology

    Professor Masao Matsuoka

  51. Conference Highlights of the 16th International Conference on Human Retrovirology: HTLV and Related Retroviruses, 26–30 June 2013, Montreal, Canada

    Article • Retrovirology, February 2014, Springer Science + Business Media

    Dr Kathryn S Jones, Professor Masao Matsuoka

  52. Epstein–Barr Viral Load is Associated to Response in AIDS-Related Lymphomas

    Article • Indian Journal of Hematology and Blood Transfusion, February 2014, Springer Science + Business Media

    Professor Masao Matsuoka

  53. Involvement of double-stranded RNA-dependent protein kinase and antisense viral RNA in the constitutive NFκB activation in adult T-cell leukemia/lymphoma cells

    Article • Leukemia, January 2014, Springer Science + Business Media

    Professor Masao Matsuoka

  54. Controlling leucine-zipper partner recognition in cells through modification of a–g interactions

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Katja Arndt, Professor Masao Matsuoka

  55. HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP

    Article • Virology Journal, January 2014, Springer Science + Business Media

    Professor Masao Matsuoka

  56. Human T-Cell Leukemia Virus Type 1: Pathogenesis and Host Immune Response

    Article • January 2014, Springer Science + Business Media

    Professor Masao Matsuoka

  57. HIV-1 Vpr Accelerates Viral Replication during Acute Infection by Exploitation of Proliferating CD4+ T Cells In Vivo

    Article • PLoS Pathogens, December 2013, PLOS

    Professor Masao Matsuoka

  58. HTLV-1 bZIP factor supports proliferation of adult T cell leukemia cells through suppression of C/EBPα signaling

    Article • Retrovirology, December 2013, Springer Science + Business Media

    Professor Masao Matsuoka

  59. Human T-cell leukemia virus type 1: replication, proliferation and propagation by Tax and HTLV-1 bZIP factor

    Article • Current Opinion in Virology, December 2013, Elsevier

    Professor Masao Matsuoka

  60. HTLV-1 bZIP Factor Suppresses Apoptosis by Attenuating the Function of FoxO3a and Altering Its Localization

    Article • Cancer Research, October 2013, American Association for Cancer Research (AACR)

    Professor Masao Matsuoka

  61. HTLV-1 bZIP Factor Induces Inflammation through Labile Foxp3 Expression

    Article • PLoS Pathogens, September 2013, PLOS

    Professor Masao Matsuoka

  62. Structure–activity relationship study of phenylpyrazole derivatives as a novel class of anti-HIV agents

    Article • Bioorganic & Medicinal Chemistry Letters, August 2013, Elsevier

    Kazuya SHIMURA, Professor Masao Matsuoka

  63. HIV-1 Resistance Mechanism to an Electrostatically Constrained Peptide Fusion Inhibitor That Is Active against T-20-Resistant Strains

    Article • Antimicrobial Agents and Chemotherapy, May 2013, ASM Journals

    Eiichi Kodama, Professor Masao Matsuoka

  64. Virological and immunological mechanisms in the pathogenesis of human T-cell leukemia virus type 1

    Article • Reviews in Medical Virology, April 2013, Wiley

    Professor Masao Matsuoka

  65. Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 404182

    Article • Bioorganic & Medicinal Chemistry, April 2013, Elsevier

    Kazuya SHIMURA, Professor Masao Matsuoka

  66. Mechanism of resistance to S138A substituted enfuvirtide and its application to peptide design

    Article • The International Journal of Biochemistry & Cell Biology, April 2013, Elsevier

    Kazuya SHIMURA, Professor Masao Matsuoka

  67. Comprehensive In Vitro Analysis of Simian Retrovirus Type 4 Susceptibility to Antiretroviral Agents

    Article • Journal of Virology, January 2013, ASM Journals

    Kazuya SHIMURA, Professor Masao Matsuoka

  68. Characterization of simian T-cell leukemia virus type 1 in naturally infected Japanese macaques as a model of HTLV-1 infection

    Article • Retrovirology, January 2013, Springer Science + Business Media

    Professor Masao Matsuoka

  69. Structure–activity relationship study of pyrimido[1,2-c][1,3]benzothiazin-6-imine derivatives for potent anti-HIV agents

    Article • Bioorganic & Medicinal Chemistry, November 2012, Elsevier

    Kazuya SHIMURA, Professor Masao Matsuoka

  70. CXCR4 Stimulates Macropinocytosis: Implications for Cellular Uptake of Arginine-Rich Cell-Penetrating Peptides and HIV

    Article • Chemistry & Biology, November 2012, Elsevier

    Kazuya SHIMURA, Professor Masao Matsuoka

  71. HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells

    Article • Oncogene, October 2012, Springer Science + Business Media

    Professor Masao Matsuoka

  72. A simple, rapid, and sensitive system for the evaluation of anti-viral drugs in rats

    Article • Biochemical and Biophysical Research Communications, July 2012, Elsevier

    Professor Masao Matsuoka

  73. Human T-Cell Leukemia Virus Type 1 (HTLV-1) bZIP Factor Requires Cellular Transcription Factor JunD To Upregulate HTLV-1 Antisense Transcription from the 3' Long Terminal Repeat

    Article • Journal of Virology, June 2012, ASM Journals

    Professor Masao Matsuoka

  74. HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+T cells in virus-infected individuals

    Article • Retrovirology, May 2012, Springer Science + Business Media

    Professor Masao Matsuoka

  75. Development and application of fluorescent SDF-1 derivatives

    Article • Future Medicinal Chemistry, May 2012, Future Science

    Professor Masao Matsuoka

  76. FOXP3+ regulatory and TIA-1+ cytotoxic T lymphocytes in HIV-associated Hodgkin lymphoma

    Article • Pathology International, January 2012, Wiley

    Professor Masao Matsuoka

  77. Concise synthesis and anti-HIV activity of pyrimido[1,2-c][1,3]benzothiazin-6-imines and related tricyclic heterocycles

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Kazuya SHIMURA, Professor Masao Matsuoka

  78. HBZ and its roles in HTLV-1 oncogenesis

    Article • Frontiers in Microbiology, January 2012, Frontiers

    Professor Masao Matsuoka

  79. The 2011 Retrovirology Prize winner Masao Matsuoka: forward looking and antisense

    Article • Retrovirology, December 2011, Springer Science + Business Media

    Professor Masao Matsuoka

  80. HTLV-1 bZIP factor impairs cell-mediated immunity by suppressing production of Th1 cytokines

    Article • Blood, November 2011, American Society of Hematology

    Professor Masao Matsuoka

  81. HTLV-2 APH-2 Expression Is Correlated With Proviral Load but APH-2 Does Not Promote Lymphocytosis

    Article • The Journal of Infectious Diseases, November 2011, Oxford University Press (OUP)

    Professor Masao Matsuoka

  82. Guest editorial: a new era of ATL and HTLV-1 research

    Article • International Journal of Hematology, October 2011, Springer Science + Business Media

    Professor Masao Matsuoka

  83. Potent Anti-HIV-1 Activity of N-HR-Derived Peptides Including a Deep Pocket-Forming Region without Antagonistic Effects on T-20

    Article • Antiviral Chemistry and Chemotherapy, October 2011, SAGE Publications

    Professor Masao Matsuoka

  84. Molecular mechanisms of HTLV-1 infection and pathogenesis

    Article • International Journal of Hematology, September 2011, Springer Science + Business Media

    Professor Masao Matsuoka

  85. HTLV-1 bZIP factor enhances TGF-  signaling through p300 coactivator

    Article • Blood, June 2011, American Society of Hematology

    Professor Masao Matsuoka

  86. Detection of HTLV-1 by means of HBZ gene in situ hybridization in formalin-fixed and paraffin-embedded tissues

    Article • Cancer Science, May 2011, Wiley

    Professor Masao Matsuoka

  87. A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized mice

    Article • Blood, April 2011, American Society of Hematology

    Professor Masao Matsuoka

  88. Potent CXCR4 Antagonists Containing Amidine Type Peptide Bond Isosteres

    Article • ACS Medicinal Chemistry Letters, March 2011, American Chemical Society (ACS)

    Kazuya SHIMURA, Professor Masao Matsuoka

  89. HTLV-1 bZIP Factor Induces T-Cell Lymphoma and Systemic Inflammation In Vivo

    Article • PLoS Pathogens, February 2011, PLOS

    Dr Masahiro Ono, Professor Masao Matsuoka

  90. ATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells

    Article • Retrovirology, January 2011, Springer Science + Business Media

    Professor Masao Matsuoka

  91. Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy

    Article • Oncogene, November 2010, Springer Science + Business Media

    Professor Masao Matsuoka

  92. Revisiting Human IL-12Rβ1 Deficiency

    Article • Medicine, November 2010, Wolters Kluwer Health

    Professor Masao Matsuoka

  93. Resistance Profiles of Novel Electrostatically Constrained HIV-1 Fusion Inhibitors

    Article • Journal of Biological Chemistry, October 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Masao Matsuoka

  94. HTLV-1 bZIP factor gene: Its roles in HTLV-1 pathogenesis

    Article • Molecular Aspects of Medicine, October 2010, Elsevier

    Professor Masao Matsuoka

  95. Rev-derived peptides inhibit HIV-1 replication by antagonism of Rev and a co-receptor, CXCR4

    Article • The International Journal of Biochemistry & Cell Biology, September 2010, Elsevier

    Professor Masao Matsuoka

  96. Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino-terminal heptad repeat

    Article • Antiviral Research, August 2010, Elsevier

    Kazuya SHIMURA, Professor Masao Matsuoka

  97. APOBEC3G Generates Nonsense Mutations in Human T-Cell Leukemia Virus Type 1 Proviral Genomes In Vivo

    Article • Journal of Virology, May 2010, ASM Journals

    Professor Masao Matsuoka

  98. Binding of anionic porphyrins with V3 Loop fragments of HIV-1 envelope

    Article • Chemistry - An Asian Journal, April 2010, Wiley

    Dr Katsumi Iga, Professor Masao Matsuoka

  99. Affinity selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors directed at the drug-resistant variants

    Article • MedChemComm, January 2010, Royal Society of Chemistry

    Professor Masao Matsuoka

  100. Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres

    Article • Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry

    Professor Masao Matsuoka

  101. Multi-Step Aberrant CpG Island Hyper-Methylation Is Associated with the Progression of Adult T–Cell Leukemia/Lymphoma

    Article • American Journal Of Pathology, January 2010, Elsevier

    Professor Masao Matsuoka

  102. Bioorganic synthesis of a recombinant HIV-1 fusion inhibitor, SC35EK, with an N-terminal pyroglutamate capping group

    Article • Bioorganic & Medicinal Chemistry, December 2009, Elsevier

    Professor Masao Matsuoka

  103. Bioorganic synthesis of end-capped anti-HIV peptides by simultaneous cyanocysteine-mediated cleavages of recombinant proteins

    Article • Bioorganic & Medicinal Chemistry, November 2009, Elsevier

    Professor Masao Matsuoka

  104. Mechanism of Inhibition of HIV-1 Reverse Transcriptase by 4′-Ethynyl-2-fluoro-2′-deoxyadenosine Triphosphate, a Translocation-defective Reverse Transcriptase Inhibitor

    Article • Journal of Biological Chemistry, October 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Masao Matsuoka

  105. X-ray Crystallographic Study of an HIV-1 Fusion Inhibitor with the gp41 S138A Substitution

    Article • Journal of Molecular Biology, September 2009, Elsevier

    Professor Masao Matsuoka

  106. The HBZ gene, a key player in HTLV-1 pathogenesis

    Article • Retrovirology, August 2009, Springer Science + Business Media

    Professor Masao Matsuoka

  107. Design and synthesis of membrane fusion inhibitors against the feline immunodeficiency virus

    Article • Bioorganic & Medicinal Chemistry, July 2009, Elsevier

    Professor Masao Matsuoka

  108. Clinical relevance of substitutions in the connection subdomain and RNase H domain of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naïve patients

    Article • Antiviral Research, June 2009, Elsevier

    Professor Masao Matsuoka

  109. HBZ is an immunogenic protein, but not a target antigen for human T-cell leukemia virus type 1-specific cytotoxic T lymphocytes

    Article • Journal of General Virology, May 2009, Society for General Microbiology

    Professor Masao Matsuoka

  110. Synonymous mutations in stem-loop III of Rev responsive elements enhance HIV-1 replication impaired by primary mutations for resistance to enfuvirtide

    Article • Antiviral Research, April 2009, Elsevier

    Kazuya SHIMURA, Professor Masao Matsuoka

  111. Electrostatically constrained α-helical peptide inhibits replication of HIV-1 resistant to enfuvirtide

    Article • The International Journal of Biochemistry & Cell Biology, April 2009, Elsevier

    Professor Masao Matsuoka

  112. In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

    Article • Retrovirology, February 2009, Springer Science + Business Media

    Professor Masao Matsuoka

  113. Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF- B

    Article • Blood, January 2009, American Society of Hematology

    Professor Masao Matsuoka

  114. Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of α-helical anti-HIV peptide analogues

    Article • Organic & Biomolecular Chemistry, January 2009, Royal Society of Chemistry

    Professor Masao Matsuoka

  115. Maximizing Functional Photoreceptor Differentiation from Adult Human Retinal Stem Cells

    Article • Stem Cells, January 2009, Wiley

    Professor Masao Matsuoka

  116. DNA double strand break repair enzymes function at multiple steps in retroviral infection

    Article • Retrovirology, January 2009, Springer Science + Business Media

    Professor Masao Matsuoka

  117. Development of a Novel Fusion Inhibitor against T-20-resistant HIV-1

    Article • January 2009, Springer Science + Business Media

    Professor Masao Matsuoka

  118. SC29EK, a Peptide Fusion Inhibitor with Enhanced α-Helicity, Inhibits Replication of Human Immunodeficiency Virus Type 1 Mutants Resistant to Enfuvirtide

    Article • Antimicrobial Agents and Chemotherapy, December 2008, ASM Journals

    Professor Masao Matsuoka

  119. Design of Peptide-based Inhibitors for Human Immunodeficiency Virus Type 1 Strains Resistant to T-20

    Article • Journal of Biological Chemistry, December 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Masao Matsuoka

  120. SKI and MEL1 Cooperate to Inhibit Transforming Growth Factor-β Signal in Gastric Cancer Cells

    Article • Journal of Biological Chemistry, December 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Masao Matsuoka

  121. Roles for MicroRNAs, miR-93 and miR-130b, and Tumor Protein 53–Induced Nuclear Protein 1 Tumor Suppressor in Cell Growth Dysregulation by Human T-Cell Lymphotrophic Virus 1

    Article • Cancer Research, October 2008, American Association for Cancer Research (AACR)

    Professor Masao Matsuoka

  122. Identification of minimal sequence for HIV-1 fusion inhibitors

    Article • Bioorganic & Medicinal Chemistry, October 2008, Elsevier

    Professor Masao Matsuoka

  123. Novel screening systems for HIV-1 fusion mediated by two extra-virion heptad repeats of gp41

    Article • Antiviral Research, October 2008, Elsevier

    Professor Masao Matsuoka

  124. Transcriptional Control of Spliced and Unspliced Human T-Cell Leukemia Virus Type 1 bZIP Factor (HBZ) Gene

    Article • Journal of Virology, July 2008, ASM Journals

    Professor Masao Matsuoka

  125. A Potential Link between Alternative Splicing of theNBS1Gene and DNA Damage/Environmental Stress

    Article • Radiation Research, July 2008, Radiation Research Society

    Professor Masao Matsuoka

  126. Identification of novel non-peptide CXCR4 antagonists by ligand-based design approach

    Article • Bioorganic & Medicinal Chemistry Letters, July 2008, Elsevier

    Professor Masao Matsuoka

  127. Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced-Intensity Conditioning for Adult T Cell Leukemia/Lymphoma: Impact of Antithymocyte Globulin on Clinical Outcome

    Article • Biology of Blood and Marrow Transplantation, June 2008, Elsevier

    Professor Masao Matsuoka

  128. Synthesis and Application of Fluorescein- and Biotin-Labeled Molecular Probes for the Chemokine Receptor CXCR4

    Article • ChemBioChem, May 2008, Wiley

    Professor Masao Matsuoka

  129. Design of a Novel HIV-1 Fusion Inhibitor That Displays a Minimal Interface for Binding Affinity

    Article • Journal of Medicinal Chemistry, February 2008, American Chemical Society (ACS)

    Professor Masao Matsuoka

  130. Amino Acid Mutation N348I in the Connection Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confers Multiclass Resistance to Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitors

    Article • Journal of Virology, January 2008, ASM Journals

    Professor Masao Matsuoka

  131. 2′-Deoxy-4′-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants

    Article • The International Journal of Biochemistry & Cell Biology, January 2008, Elsevier

    Professor Masao Matsuoka

  132. Dual-Reporter Phenotypic Assay for Human Immunodeficiency Viruses

    Article • Journal of Clinical Microbiology, December 2007, ASM Journals

    Professor Masao Matsuoka

  133. 2′-Deoxy-4′-C-Ethynyl-2-Fluoroadenosine: A Nucleoside Reverse Transcriptase Inhibitor with Highly Potent Activity Against Wide Spectrum of HIV-1 Strains, Favorable Toxic Profiles, and Stability in Plasma

    Article • Nucleosides Nucleotides & Nucleic Acids, November 2007, Taylor & Francis

    Professor Masao Matsuoka

  134. Meeting Report on the 13th International Conference on Human Retrovirology: Human T-Cell Leukemia Virus Research 30 Years after Adult T-Cell Leukemia

    Article • Cancer Research, November 2007, American Association for Cancer Research (AACR)

    Professor Masao Matsuoka

  135. Broad Antiretroviral Activity and Resistance Profile of the Novel Human Immunodeficiency Virus Integrase Inhibitor Elvitegravir (JTK-303/GS-9137)

    Article • Journal of Virology, October 2007, ASM Journals

    Kazuya SHIMURA, Professor Masao Matsuoka

  136. Heptad Repeat-Derived Peptides Block Protease-Mediated Direct Entry from the Cell Surface of Severe Acute Respiratory Syndrome Coronavirus but Not Entry via the Endosomal Pathway

    Article • Journal of Virology, October 2007, ASM Journals

    Professor Masao Matsuoka

  137. GANP suppresses DNA recombination, measured by direct-repeat ?-galactosidase gene construct, but does not suppress the type of recombination applying to immunoglobulin genes in mammalian cells

    Article • Genes to Cells, October 2007, Wiley

    Professor Masao Matsuoka

  138. Cooperation of NF-κB2/p100 Activation and the PDZ Domain Binding Motif Signal in Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax1 but Not HTLV-2 Tax2 Is Crucial for Interleukin-2-Independent Growth Transformation of a T-Cell Line

    Article • Journal of Virology, August 2007, ASM Journals

    Professor Masao Matsuoka

  139. Implication of the HTLV-I bZIP Factor Gene in the Leukemogenesis of Adult T-Cell Leukemia

    Article • International Journal of Hematology, August 2007, Springer Science + Business Media

    Professor Masao Matsuoka

  140. Activity against Human Immunodeficiency Virus Type 1, Intracellular Metabolism, and Effects on Human DNA Polymerases of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine

    Article • Antimicrobial Agents and Chemotherapy, June 2007, ASM Journals

    Dr Masayuki Amano, Professor Masao Matsuoka

  141. Development of adult T-cell leukemia in donor-derived human T-cell leukemia virus type I-infected T cells after allogeneic bone marrow transplantation

    Article • Leukemia, April 2007, Springer Science + Business Media

    Professor Masao Matsuoka

  142. Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation

    Article • Nature Reviews Cancer, April 2007, Springer Science + Business Media

    Professor Masao Matsuoka

  143. Preferential Selection of Human T-Cell Leukemia Virus Type 1 Provirus Lacking the 5′ Long Terminal Repeat during Oncogenesis

    Article • Journal of Virology, March 2007, ASM Journals

    Professor Masao Matsuoka

  144. Phenotypic and Genotypic Comparisons of Human T-Cell Leukemia Virus Type 1 Reverse Transcriptases from Infected T-Cell Lines and Patient Samples

    Article • Journal of Virology, February 2007, ASM Journals

    Professor Masao Matsuoka

  145. Leukaemogenic mechanism of human T-cell leukaemia virus type I

    Article • Reviews in Medical Virology, January 2007, Wiley

    Professor Masao Matsuoka

  146. Chromosomal abnormalities in non-hodgkin lymphoma with peripheral t-cell type: Effect of HTLV-I infection

    Article • Hematological Oncology, October 2006, Wiley

    Professor Masao Matsuoka

  147. De Novo Human T-Cell Leukemia Virus Type 1 Infection of Human Lymphocytes in NOD-SCID, Common γ-Chain Knockout Mice

    Article • Journal of Virology, August 2006, ASM Journals

    Professor Masao Matsuoka

  148. EGFRMutations in Small-Cell Lung Cancers in Patients Who Have Never Smoked

    Article • New England Journal of Medicine, July 2006, New England Journal of Medicine (NEJM/MMS)

    Professor Masao Matsuoka

  149. Correction for Satou et al., HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells

    Article • Proceedings of the National Academy of Sciences, June 2006, Proceedings of the National Academy of Sciences

    Professor Masao Matsuoka

  150. Donor-Derived T-Cell Leukemia after Bone Marrow Transplantation

    Article • New England Journal of Medicine, April 2006, New England Journal of Medicine (NEJM/MMS)

    Professor Masao Matsuoka

  151. Ars Insulator Identified in Sea Urchin Possesses an Activity to Ensure the Transgene Expression in Mouse Cells

    Article • The Journal of Biochemistry, April 2006, Oxford University Press (OUP)

    Professor Masao Matsuoka

  152. Sea Urchin Arylsulfatase Insulator Exerts its Anti-silencing Effect without Interacting with the Nuclear Matrix

    Article • Journal of Molecular Biology, March 2006, Elsevier

    Professor Masao Matsuoka

  153. Novel HIV-1 Integrase Inhibitors Derived from Quinolone Antibiotics

    Article • Journal of Medicinal Chemistry, March 2006, American Chemical Society (ACS)

    Professor Masao Matsuoka

  154. HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells

    Article • Proceedings of the National Academy of Sciences, January 2006, Proceedings of the National Academy of Sciences

    Professor Masao Matsuoka

  155. Article • Uirusu, January 2006, Japanese Association of Virology

    Professor Masao Matsuoka

  156. Non-Hodgkin's Lymphomas of Childhood

    Article • January 2006, Elsevier

    Professor Masao Matsuoka

  157. Loss of interleukin-2-dependency in HTLV-I-infected T cells on gene silencing of thioredoxin-binding protein-2

    Article • Oncogene, November 2005, Springer Science + Business Media

    Professor Masao Matsuoka

  158. Natural history of adult T-cell leukemia/lymphoma and approaches to therapy

    Article • Oncogene, September 2005, Springer Science + Business Media

    Professor Masao Matsuoka

  159. Halogenated Thymidine Analogues Restore the Expression of Silenced Genes without Demethylation

    Article • Cancer Research, August 2005, American Association for Cancer Research (AACR)

    Professor Masao Matsuoka

  160. Human T-Cell Leukemia Virus Type I at Age 25: A Progress Report: Figure 1.

    Article • Cancer Research, June 2005, American Association for Cancer Research (AACR)

    Professor Masao Matsuoka

  161. Preferential selection of human T-cell leukemia virus type I provirus integration sites in leukemic versus carrier states

    Article • Blood, April 2005, American Society of Hematology

    Professor Masao Matsuoka

  162. Studies of non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Synthesis and structure–activity relationships of 2-cyano and 2-hydroxy thiazolidenebenzenesulfonamide derivatives

    Article • Bioorganic & Medicinal Chemistry, February 2005, Elsevier

    Professor Masao Matsuoka

  163. Mutations Conferring Resistance to Human Immunodeficiency Virus Type 1 Fusion Inhibitors Are Restricted by gp41 and Rev-Responsive Element Functions

    Article • Journal of Virology, January 2005, ASM Journals

    Professor Masao Matsuoka

  164. Article • Retrovirology, January 2005, Springer Science + Business Media

    Professor Masao Matsuoka

  165. RNase S complex bearing arginine-rich peptide and anti-HIV activity

    Article • Journal of Molecular Recognition, January 2005, Wiley

    Professor Masao Matsuoka

  166. Article • Retrovirology, January 2005, Springer Science + Business Media

    Professor Masao Matsuoka

  167. Design, Efficient Synthesis, and Anti‐HIV Activity of 4′‐C‐Cyano‐ and 4′‐C‐Ethynyl‐2′‐deoxy Purine Nucleosides

    Article • Nucleosides Nucleotides & Nucleic Acids, December 2004, Taylor & Francis

    Professor Masao Matsuoka

  168. Studies of nonnucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Design and synthesis of thiazolidenebenzenesulfonamides

    Article • Bioorganic & Medicinal Chemistry, December 2004, Elsevier

    Professor Masao Matsuoka

  169. Novel patterns of nevirapine resistance-associated mutations of human immunodeficiency virus type 1 in treatment-naïve patients

    Article • Virology, October 2004, Elsevier

    Professor Masao Matsuoka

  170. Identification of Aberrantly Methylated Genes in Association with Adult T-Cell Leukemia

    Article • Cancer Research, September 2004, American Association for Cancer Research (AACR)

    Professor Masao Matsuoka

  171. Proteasome inhibitor, bortezomib, potently inhibits the growth of adult T-cell leukemia cells both in vivo and in vitro

    Article • Leukemia, June 2004, Springer Science + Business Media

    Professor Masao Matsuoka

  172. Role of HTLV-1 proviral DNA load and clonality in the development of adult T-cell leukemia/lymphoma in asymptomatic carriers

    Article • International Journal of Cancer, April 2004, Wiley

    Professor Masao Matsuoka

  173. Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells

    Article • Blood, April 2004, American Society of Hematology

    Professor Masao Matsuoka

  174. Sea urchin insulator protects lentiviral vector from silencing by maintaining active chromatin structure

    Article • Gene Therapy, February 2004, Springer Science + Business Media

    Professor Masao Matsuoka

  175. Genetic and epigenetic inactivation oftax gene in adult T-cell leukemia cells

    Article • International Journal of Cancer, January 2004, Wiley

    Professor Masao Matsuoka

  176. Synthesis of 4′-C-Ethynyl and 4′-C-Cyano Purine Nucleosides from Natural Nucleosides and Their Anti-HIV Activity

    Article • Nucleosides Nucleotides & Nucleic Acids, October 2003, Taylor & Francis

    Professor Masao Matsuoka

  177. Human T-cell leukemia virus type I and adult T-cell leukemia

    Article • Oncogene, August 2003, Springer Science + Business Media

    Professor Masao Matsuoka

  178. Influence of cytokine and mannose binding protein gene polymorphisms on human t-cell leukemia virus type i (hTLV-i) provirus load in HTLV-I asymptomatic carriers

    Article • Human Immunology, April 2003, Elsevier

    Professor Masao Matsuoka

  179. Association between interleukin-6 gene polymorphism and human T-Cell leukemia virus type I associated myelopathy

    Article • Human Immunology, August 2002, Elsevier

    Professor Masao Matsuoka

  180. Central nervous system lesions in adult T-cell leukaemia: MRI and pathology

    Article • Neuroradiology, July 2002, Springer Science + Business Media

    Professor Masao Matsuoka

  181. Involvement of IL-2/IL-2R system activation by parasite antigen in polyclonal expansion of CD4+25+ HTLV-1-infected T-cells in human carriers of both HTLV-1 and S. stercoralis

    Article • Oncogene, April 2002, Springer Science + Business Media

    Professor Masao Matsuoka

  182. Genetic Evidence of Transmission of Human T Cell Lymphotropic Virus Type 1 between Spouses

    Article • The Journal of Infectious Diseases, March 2002, Oxford University Press (OUP)

    Professor Masao Matsuoka

  183. Mechanism of hypercalcemia in adult T-cell leukemia: overexpression of receptor activator of nuclear factor kappa B ligand on adult T-cell leukemia cells

    Article • Blood, January 2002, American Society of Hematology

    Professor Masao Matsuoka

  184. Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140

    Article • Bioorganic & Medicinal Chemistry Letters, July 2001, Elsevier

    Professor Masao Matsuoka

  185. Synthetic peptide-based electrochemiluminescence immunoassay for anti-Borna disease virus p40 and p24 antibodies in rat and horse serum

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, July 2001, SAGE Publications

    Professor Masao Matsuoka

  186. Impaired production of naive T lymphocytes in human T-cell leukemia virus type I-infected individuals: its implications in the immunodeficient state

    Article • Blood, May 2001, American Society of Hematology

    Professor Masao Matsuoka

  187. 4′-Ethynyl Nucleoside Analogs: Potent Inhibitors of Multidrug-Resistant Human Immunodeficiency Virus Variants In Vitro

    Article • Antimicrobial Agents and Chemotherapy, May 2001, ASM Journals

    Professor Masao Matsuoka

  188. Missense mutation of the interleukin-12 receptor beta1 chain-encoding gene is associated with impaired immunity against Mycobacterium avium complex infection

    Article • Blood, May 2001, American Society of Hematology

    Professor Masao Matsuoka

  189. Sequential Change of Virus Markers in Seroconverters with Community‐Acquired Infection of Human T Lymphotropic Virus Type I

    Article • The Journal of Infectious Diseases, April 2001, Oxford University Press (OUP)

    Professor Masao Matsuoka

  190. The possible involvement of CXCR4 in the inhibition of HIV-1 infection mediated by DP178/gp41

    Article • FEBS Letters, December 2000, Wiley

    Professor Masao Matsuoka

  191. Tumor necrosis factor, tumor necrosis factor receptors type 1 and 2, lymphotoxin-α, and HLA-DRB1 gene polymorphisms in human T-Cell lymphotropic virus type I associated myelopathy

    Article • Human Immunology, December 2000, Elsevier

    Hideshi Kawakami, Professor Masao Matsuoka

  192. Syntheses of 4‘-C-Ethynyl-β-d-arabino-and 4‘-C-Ethynyl-2‘-deoxy-β-d-ribo-pentofuranosylpyrimidines and -purines and Evaluation of Their Anti-HIV Activity

    Article • Journal of Medicinal Chemistry, November 2000, American Chemical Society (ACS)

    Professor Masao Matsuoka

  193. Identification of Human Autoantibodies to the Transcriptional Repressor ZF5

    Article • Journal of Autoimmunity, August 2000, Elsevier

    Professor Masao Matsuoka

  194. Polymorphism of the 5′‐Flanking Region of the Tumor Necrosis Factor (TNF)–α Gene and Susceptibility to Human T‐Cell Lymphotropic Virus Type I (HTLV‐I) Uveitis

    Article • The Journal of Infectious Diseases, September 1999, Oxford University Press (OUP)

    Professor Masao Matsuoka

  195. Rapid quantification of HTLV-I provirus load: Detection of monoclonal proliferation of HTLV-I-infected cells among blood donors

    Article • International Journal of Cancer, June 1999, Wiley

    Professor Masao Matsuoka

  196. Random integration of HTLV-I provirus; increasing chromosomal instability

    Article • Cancer Letters, October 1998, Elsevier

    Professor Masao Matsuoka

  197. Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins

    Article • Proceedings of the National Academy of Sciences, December 1997, Proceedings of the National Academy of Sciences

    Professor Masao Matsuoka

  198. DNA Diagnosis of HTLV-I

    Article • Intervirology, January 1996, Karger Publishers

    Professor Masao Matsuoka

  199. The 3′ enhancer region determines the B/T specificity and pro-B/pre-B specificity of immunoglobulin Vκ-Jκ joining

    Article • Cell, December 1995, Elsevier

    Professor Masao Matsuoka

  200. Deregulated c-fos Modulates B Cell Responses to Switch Mediators

    Article • Cellular Immunology, June 1993, Elsevier

    Professor Masao Matsuoka

  201. Immunoglobulin switch circular DNA in the mouse infected with Nippostrongylus brasiliensis: evidence for successive class switching from mu to epsilon via gamma 1.

    Article • Proceedings of the National Academy of Sciences, October 1990, Proceedings of the National Academy of Sciences

    Professor Masao Matsuoka

  202. A B-CELL LINE HAVING CHROMOSOME 14 ABERRATION AT BREAK BAND qll DERIVED FROM AN ADULT T-CELL LEUKEMIA PATIENT

    Article • Japanese Journal of Cancer Research, January 1988, Wiley

    Professor Masao Matsuoka

  203. Expression of the HT462 antigen on fresh leukemic T cells and on cells of HTLV-I infected lines

    Article • Leukemia Research, January 1987, Elsevier

    Professor Masao Matsuoka

  204. T Cell γ Chain Gene Rearrangement without T Cell Receptor β Chain Gene Rearrangement in Two Cases of Non-Hodgkin’s Lymphoma

    Article • Acta Haematologica, January 1987, Karger Publishers

    Professor Masao Matsuoka

  205. Analysis of anti-HTLV-I antibody by strip radioimmunoassay—comparison with indirect immunofluorescence assay, enzyme-linked immunosorbent assay and membrane immunofluorescence assay

    Article • Leukemia Research, January 1986, Elsevier

    Professor Masao Matsuoka

  206. Expression of tac antigen on human immature B-cell lineage leukemic cells

    Article • Leukemia Research, January 1986, Elsevier

    Professor Masao Matsuoka

  207. HTLV-III Infection and Epitope Recognition by OKT4 Monoclonal Antibody

    Article • New England Journal of Medicine, December 1985, New England Journal of Medicine (NEJM/MMS)

    Professor Masao Matsuoka